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Most cited papers from Istituto Oncologico Veneto

What are the most cited papers from Istituto Oncologico Veneto?

The most cited paper from Istituto Oncologico Veneto is "Five-Year Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma" (James Larkin et al., 2019), with 3,784 citations. Next come "Olaparib for Metastatic Breast Cancer in Patients with a Germline BRCA Mutation" (3,322) and "Dabrafenib in BRAF-mutated metastatic melanoma: a multicentre, open-label, phase 3 randomised controlled trial" (3,009).

Showing 50 of 60 papers. Every paper with more than 672 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Five-Year Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma James Larkin et al. · New England Journal of Medicine Open access 28 Sep 2019 3,784
2 Olaparib for Metastatic Breast Cancer in Patients with a Germline BRCA Mutation Mark E. Robson, Seock‐Ah Im, Elżbieta Senkus et al. · New England Journal of Medicine Open access 4 Jun 2017 3,322
3 Dabrafenib in BRAF-mutated metastatic melanoma: a multicentre, open-label, phase 3 randomised controlled trial Axel Hauschild et al. · The Lancet 25 Jun 2012 3,009
4 Nivolumab in patients with metastatic DNA mismatch repair-deficient or microsatellite instability-high colorectal cancer (CheckMate 142): an open-label, multicentre, phase 2 study Michael James Overman, Ray McDermott, Joseph L. Leach et al. · The Lancet Oncology Open access 19 Jul 2017 2,883
5 Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards Vincenzo Bronte, Sven Brandau, Shu‐Hsia Chen et al. · Nature Communications Open access 6 Jul 2016 2,806
6 Improved Overall Survival in Melanoma with Combined Dabrafenib and Trametinib Caroline Robert et al. · New England Journal of Medicine Open access 16 Nov 2014 2,718
7 Alpelisib for PIK3CA -Mutated, Hormone Receptor–Positive Advanced Breast Cancer Fabrice André, Eva M. Ciruelos, Gábor Rubovszky et al. · New England Journal of Medicine Open access 15 May 2019 2,660
8 Pembrolizumab in patients with advanced hepatocellular carcinoma previously treated with sorafenib (KEYNOTE-224): a non-randomised, open-label phase 2 trial Andrew Xiuxuan Zhu et al. · The Lancet Oncology 3 Jun 2018 2,555
9 Cabozantinib in Patients with Advanced and Progressing Hepatocellular Carcinoma Ghassan K. Abou‐Alfa et al. · New England Journal of Medicine Open access 4 Jul 2018 2,386
10 PD-L1 is a novel direct target of HIF-1α, and its blockade under hypoxia enhanced MDSC-mediated T cell activation Muhammad Zaeem Noman, Giacomo Desantis, Bassam Janji et al. · The Journal of Experimental Medicine Open access 28 Apr 2014 2,205
11 Durable Clinical Benefit With Nivolumab Plus Ipilimumab in DNA Mismatch Repair–Deficient/Microsatellite Instability–High Metastatic Colorectal Cancer Michael James Overman, Sara Lonardi, Ka Yeung Mark Wong et al. · Journal of Clinical Oncology Open access 20 Jan 2018 2,121
12 Ribociclib as First-Line Therapy for HR-Positive, Advanced Breast Cancer Gabriel N. Hortobágyi et al. · New England Journal of Medicine Open access 8 Oct 2016 2,066
13 Osimertinib in Resected EGFR -Mutated Non–Small-Cell Lung Cancer Yi-Long Lung Cancer Wu et al. · New England Journal of Medicine Open access 19 Sep 2020 1,809
14 Nivolumab plus Cabozantinib versus Sunitinib for Advanced Renal-Cell Carcinoma Toni K. Choueiri et al. · New England Journal of Medicine Open access 3 Mar 2021 1,801
15 Encorafenib, Binimetinib, and Cetuximab in BRAF V600E–Mutated Colorectal Cancer Scott Kopetz et al. · New England Journal of Medicine Open access 30 Sep 2019 1,500
16 Nivolumab plus ipilimumab or nivolumab alone versus ipilimumab alone in advanced melanoma (CheckMate 067): 4-year outcomes of a multicentre, randomised, phase 3 trial Frank Stephen Hodi, Vanna Chiarion‐Sileni, Rene C. Gonzalez et al. · The Lancet Oncology 22 Oct 2018 1,426
17 Dabrafenib and trametinib versus dabrafenib and placebo for Val600 BRAF-mutant melanoma: a multicentre, double-blind, phase 3 randomised controlled trial Georgina Venetia Long et al. · The Lancet 31 May 2015 1,419
18 Completion Dissection or Observation for Sentinel-Node Metastasis in Melanoma Mark B. Faries et al. · New England Journal of Medicine Open access 7 Jun 2017 1,415
19 The Hippo Transducer TAZ Confers Cancer Stem Cell-Related Traits on Breast Cancer Cells Michelangelo Cordenonsi, Francesca Zanconato, Luca Azzolin et al. · Cell Open access Nov 2011 1,415
20 Five-Year Outcomes with Dabrafenib plus Trametinib in Metastatic Melanoma Caroline Robert et al. · New England Journal of Medicine Open access 4 Jun 2019 1,412
21 Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth Francesca Zanconato, Mattia Forcato, Giusy Battilana et al. · Nature Cell Biology Open access 10 Aug 2015 1,309
22 Everolimus for the treatment of advanced, non-functional neuroendocrine tumours of the lung or gastrointestinal tract (RADIANT-4): a randomised, placebo-controlled, phase 3 study James C. Yao et al. · The Lancet Open access 17 Dec 2015 1,288
23 Adjuvant ipilimumab versus placebo after complete resection of high-risk stage III melanoma (EORTC 18071): a randomised, double-blind, phase 3 trial Alexander M.M. Eggermont et al. · The Lancet Oncology 5 Apr 2015 1,266
24 Altered macrophage differentiation and immune dysfunction in tumor development Antonio Sica, Vincenzo Bronte · Journal of Clinical Investigation Open access May 2007 1,247
25 Long-Term Outcomes With Nivolumab Plus Ipilimumab or Nivolumab Alone Versus Ipilimumab in Patients With Advanced Melanoma Jedd D. Wolchok et al. · Journal of Clinical Oncology Open access 24 Nov 2021 1,144
26 FOLFOXIRI plus bevacizumab versus FOLFIRI plus bevacizumab as first-line treatment of patients with metastatic colorectal cancer: updated overall survival and molecular subgroup analyses of the open-label, phase 3 TRIBE study Chiara Cremolini, Fotios Loupakis, Carlotta Antoniotti et al. · The Lancet Oncology Open access 31 Aug 2015 1,111
27 Encorafenib plus binimetinib versus vemurafenib or encorafenib in patients with BRAF-mutant melanoma (COLUMBUS): a multicentre, open-label, randomised phase 3 trial Reinhard Dummer, Paolo A. Ascierto, Helen J Gogas et al. · The Lancet Oncology Open access 21 Mar 2018 1,040
28 Abemaciclib Combined With Endocrine Therapy for the Adjuvant Treatment of HR+, HER2−, Node-Positive, High-Risk, Early Breast Cancer (monarchE) Stephen R.D. Johnston et al. · Journal of Clinical Oncology Open access 20 Sep 2020 1,037
29 Dual-targeted therapy with trastuzumab and lapatinib in treatment-refractory, KRAS codon 12/13 wild-type, HER2-positive metastatic colorectal cancer (HERACLES): a proof-of-concept, multicentre, open-label, phase 2 trial Andrea Sartore Bianchi et al. · The Lancet Oncology Open access 26 Apr 2016 1,032
30 The Effect of Abemaciclib Plus Fulvestrant on Overall Survival in Hormone Receptor–Positive, ERBB2-Negative Breast Cancer That Progressed on Endocrine Therapy—MONARCH 2 George W. Sledge, Masakazu Toi, Patrick Neven et al. · JAMA Oncology Open access 29 Sep 2019 1,016
31 Early breast cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up Sibylle Loibl et al. · Annals of Oncology Open access 13 Dec 2023 991
32 Ramucirumab versus placebo in combination with second-line FOLFIRI in patients with metastatic colorectal carcinoma that progressed during or after first-line therapy with bevacizumab, oxaliplatin, and a fluoropyrimidine (RAISE): a randomised, double-blind, multicentre, phase 3 study Josep M. Tabernero, Takayuki Yoshino, Allen Lee Cohn et al. · The Lancet Oncology 12 Apr 2015 967
33 Association Between BRAF V600E Mutation and Mortality in Patients With Papillary Thyroid Cancer Mingzhao Xing et al. · JAMA Open access 9 Apr 2013 943
34 Efficacy of human papillomavirus testing for the detection of invasive cervical cancers and cervical intraepithelial neoplasia: a randomised controlled trial Guglielmo Ronco, Paolo Giorgi Rossi, Francesca Carozzi et al. · The Lancet Oncology 19 Jan 2010 941
35 Tumor-Infiltrating Lymphocytes and Prognosis: A Pooled Individual Patient Analysis of Early-Stage Triple-Negative Breast Cancers Sherene Loi et al. · Journal of Clinical Oncology Open access 16 Jan 2019 930
36 Updated results from MONALEESA-2, a phase III trial of first-line ribociclib plus letrozole versus placebo plus letrozole in hormone receptor-positive, HER2-negative advanced breast cancer Gabriel N. Hortobágyi et al. · Annals of Oncology Open access 25 Apr 2018 893
37 Tepotinib in Non–Small-Cell Lung Cancer with MET Exon 14 Skipping Mutations Paul K. Paik et al. · New England Journal of Medicine Open access 28 May 2020 891
38 Tumor-Induced Tolerance and Immune Suppression Depend on the C/EBPβ Transcription Factor Ilaria Marigo, Erika Bosio, Samantha Solito et al. · Immunity Open access Jun 2010 854
39 Ramucirumab versus placebo as second-line treatment in patients with advanced hepatocellular carcinoma following first-line therapy with sorafenib (REACH): a randomised, double-blind, multicentre, phase 3 trial Andrew Xiuxuan Zhu, Joon Oh Park, Baek‐Yeol Ryoo et al. · The Lancet Oncology Open access 18 Jun 2015 850
40 Clinical validity of circulating tumour cells in patients with metastatic breast cancer: a pooled analysis of individual patient data François‐Clément Bidard et al. · The Lancet Oncology 11 Mar 2014 848
41 MGMT Promoter Methylation Status Can Predict the Incidence and Outcome of Pseudoprogression After Concomitant Radiochemotherapy in Newly Diagnosed Glioblastoma Patients Alba Ariela Brandes, Enrico Franceschi, Alicia Tosoni et al. · Journal of Clinical Oncology 29 Apr 2008 842
42 The Terminology Issue for Myeloid-Derived Suppressor Cells Dmitry I. Gabrilovich, Vincenzo Bronte, Shu‐Hsia Chen et al. · Cancer Research Open access 2007 827
43 Assessing Tumor-Infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method from the International Immuno-Oncology Biomarkers Working Group: Part 2: TILs in Melanoma, Gastrointestinal Tract Carcinomas, Non–Small Cell Lung Carcinoma and Mesothelioma, Endometrial and Ovarian Carcinomas, Squamous Cell Carcinoma of the Head and Neck, Genitourina Shona A. Hendry et al. · Advances in Anatomic Pathology Open access100 authors 2 Aug 2017 816
44 Cyclin G1 Is a Target of miR-122a, a MicroRNA Frequently Down-regulated in Human Hepatocellular Carcinoma Laura Gramantieri, Manuela Ferracin, Francesca Fornari et al. · Cancer Research Open access Jul 2007 816
45 Chemotherapy for Elderly Patients With Advanced Non-Small-Cell Lung Cancer: The Multicenter Italian Lung Cancer in the Elderly Study (MILES) Phase III Randomized Trial C. Gridelli et al. · JNCI Journal of the National Cancer Institute Open access 4 Mar 2003 799
46 Metabolic control of YAP and TAZ by the mevalonate pathway Giovanni Sorrentino, Naomi Ruggeri, Valeria Specchia et al. · Nature Cell Biology 23 Mar 2014 795
47 Screening tools for multidimensional health problems warranting a geriatric assessment in older cancer patients: an update on SIOG recommendations Lore Decoster, Katrien Van Puyvelde, Supriya Gupta Mohile et al. · Annals of Oncology Open access 17 Jun 2014 794
48 Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival Steffen Walter et al. · Nature Medicine 29 Jul 2012 793
49 A Mutant-p53/Smad Complex Opposes p63 to Empower TGFβ-Induced Metastasis Maddalena Adorno, Michelangelo Cordenonsi, Marco Montagner et al. · Cell Open access Apr 2009 790
50 Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells Giovanna Gallina, Luigi Dolcetti, Paolo Serafini et al. · Journal of Clinical Investigation Open access 2 Oct 2006 789

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.