Most cited papers from Janelia Research Campus
What are the most cited papers from Janelia Research Campus?
The most cited paper from Janelia Research Campus is "Imaging Intracellular Fluorescent Proteins at Nanometer Resolution" (Eric Betzig, George H. Patterson, Rachid Sougrat et al., 2006), with 9,061 citations. Next come "Accelerated Profile HMM Searches" (7,781) and "Ultrasensitive fluorescent proteins for imaging neuronal activity" (7,242).
Showing 50 of 60 papers. Every paper with more than 998 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Imaging Intracellular Fluorescent Proteins at Nanometer Resolution Eric Betzig, George H. Patterson, Rachid Sougrat et al. · Science | 10 Aug 2006 | 9,061 |
| 2 | Accelerated Profile HMM Searches Sean R. Eddy · PLoS Computational Biology | 20 Oct 2011 | 7,781 |
| 3 | Ultrasensitive fluorescent proteins for imaging neuronal activity Tsai‐Wen Chen, Trevor J. Wardill, Yi Sun et al. · Nature | 16 Jul 2013 | 7,242 |
| 4 | Pfam: the protein families database ROBERT FINN, Alex Bateman, Jody Clements et al. · Nucleic Acids Research | 27 Nov 2013 | 6,604 |
| 5 | HMMER web server: interactive sequence similarity searching ROBERT FINN, Jody Clements, Sean R. Eddy · Nucleic Acids Research | 18 May 2011 | 6,555 |
| 6 | CTFFIND4: Fast and accurate defocus estimation from electron micrographs Alexis L. Rohou, Nikolaus Grigorieff · Journal of Structural Biology | 13 Aug 2015 | 5,758 |
| 7 | An improved Greengenes taxonomy with explicit ranks for ecological and evolutionary analyses of bacteria and archaea Daniel T. McDonald, Morgan N. Price, Julia K. Goodrich et al. · The ISME Journal | Dec 2011 | 5,371 |
| 8 | Cellpose: a generalist algorithm for cellular segmentation Carsen Stringer, Tim Wang, Michalis Michaelos et al. · Nature Methods | 14 Dec 2020 | 4,662 |
| 9 | Infernal 1.1: 100-fold faster RNA homology searches Eric P. Nawrocki, Sean R. Eddy · Bioinformatics | 4 Sep 2013 | 4,029 |
| 10 | ilastik: interactive machine learning for (bio)image analysis Stuart Berg, Dominik Kutra, Thorben Kroeger et al. · Nature Methods | 30 Sep 2019 | 3,760 |
| 11 | Predicting the Functional Effect of Amino Acid Substitutions and Indels Yongwook Choi, Gregory E. Sims, Sean V. Murphy et al. · PLoS ONE | 8 Oct 2012 | 3,048 |
| 12 | The Pfam protein families database ROBERT FINN, Jaina Mistry, John G. Tate et al. · Nucleic Acids Research | 17 Nov 2009 | 2,733 |
| 13 | Trainable Weka Segmentation: a machine learning tool for microscopy pixel classification Ignacio Arganda‐Carreras, Verena Kaynig, Curtis Rueden et al. · Bioinformatics | 28 Mar 2017 | 2,553 |
| 14 | Fully integrated silicon probes for high-density recording of neural activity James Jaeyoon Jun et al. · Nature | 7 Nov 2017 | 2,453 |
| 15 | Opportunities and obstacles for deep learning in biology and medicine Travers H. Ching et al. · Journal of The Royal Society Interface | Apr 2018 | 2,322 |
| 16 | Evolution of genes and genomes on the Drosophila phylogeny Andrew G. Clark et al. · Nature | Nov 2007 | 2,132 |
| 17 | Lattice light-sheet microscopy: Imaging molecules to embryos at high spatiotemporal resolution Bi‐Chang Chen et al. · Science | 23 Oct 2014 | 2,103 |
| 18 | Shared and distinct transcriptomic cell types across neocortical areas Bosiljka Tasic et al. · Nature | 25 Oct 2018 | 2,028 |
| 19 | Experience-dependent structural synaptic plasticity in the mammalian brain Anthony J. D. G. Holtmaat, Karel Svoboda · Nature reviews. Neuroscience | 20 Aug 2009 | 2,009 |
| 20 | Challenges in homology search: HMMER3 and convergent evolution of coiled-coil regions Jaina Mistry, ROBERT FINN, Sean R. Eddy et al. · Nucleic Acids Research | 17 Apr 2013 | 1,924 |
| 21 | Neuromorphic Silicon Neuron Circuits Giacomo Indiveri, B. Linares-Barranco, Tara Julia Hamilton et al. · Frontiers in Neuroscience | 2011 | 1,844 |
| 22 | Spontaneous behaviors drive multidimensional, brainwide activity Carsen Stringer, Marius Pachitariu, Nicholas A. Steinmetz et al. · Science | 19 Apr 2019 | 1,768 |
| 23 | Reconstruction and Simulation of Neocortical Microcircuitry Henry Markram et al. · Cell | Oct 2015 | 1,703 |
| 24 | A GAL4-Driver Line Resource for Drosophila Neurobiology Arnim Jenett et al. · Cell Reports | Oct 2012 | 1,670 |
| 25 | A general method to improve fluorophores for live-cell and single-molecule microscopy Jonathan B. Grimm, Brian P. English, Jiji Chen et al. · Nature Methods | 19 Jan 2015 | 1,668 |
| 26 | Nanoscale architecture of integrin-based cell adhesions Pakorn Kanchanawong, Gleb E. Shtengel, Ana M. Pasapera et al. · Nature | Nov 2010 | 1,625 |
| 27 | Hidden Markov model speed heuristic and iterative HMM search procedure L. Steven Johnson, Sean R. Eddy, Elon Portugaly · BMC Bioinformatics | 18 Aug 2010 | 1,554 |
| 28 | A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing Linda Madisen et al. · Nature Neuroscience | 25 Mar 2012 | 1,547 |
| 29 | Infernal 1.0: inference of RNA alignments Eric P. Nawrocki, Diana L. Kolbe, Sean R. Eddy · Bioinformatics | 23 Mar 2009 | 1,508 |
| 30 | Cellpose 2.0: how to train your own model Marius Pachitariu, Carsen Stringer · Nature Methods | 7 Nov 2022 | 1,507 |
| 31 | Whole-brain functional imaging at cellular resolution using light-sheet microscopy Misha B. Ahrens, Michael B. Orger, Drew N. Robson et al. · Nature Methods | 18 Mar 2013 | 1,502 |
| 32 | A Designer AAV Variant Permits Efficient Retrograde Access to Projection Neurons D. Gowanlock R. Tervo, Bum‐Yeol Hwang, Sarada Viswanathan et al. · Neuron | Oct 2016 | 1,350 |
| 33 | High-performance calcium sensors for imaging activity in neuronal populations and microcompartments Hod Dana, Yi Sun, Boaz Mohar et al. · Nature Methods | 17 Jun 2019 | 1,347 |
| 34 | Refinement of Tools for Targeted Gene Expression in Drosophila Barret D. Pfeiffer, Teri-T B Ngo, Karen L Hibbard et al. · Genetics | 9 Aug 2010 | 1,311 |
| 35 | Optimization of a GCaMP Calcium Indicator for Neural Activity Imaging Jasper Akerboom et al. · Journal of Neuroscience | 3 Oct 2012 | 1,302 |
| 36 | Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection Alexandra East-Seletsky, Mitchell R. O’Connell, Spencer C. Knight et al. · Nature | 23 Sep 2016 | 1,276 |
| 37 | A connectome and analysis of the adult Drosophila central brain Louis K. Scheffer et al. · eLife | 3 Sep 2020 | 1,264 |
| 38 | High-density mapping of single-molecule trajectories with photoactivated localization microscopy Suliana Manley, Jennifer M. Gillette, George H. Patterson et al. · Nature Methods | 13 Jan 2008 | 1,264 |
| 39 | Optimized CRISPR/Cas tools for efficient germline and somatic genome engineering in Drosophila Fillip Port, Hui-Min Chen, Tzumin Lee et al. · Proceedings of the National Academy of Sciences | 7 Jul 2014 | 1,224 |
| 40 | Simultaneous Denoising, Deconvolution, and Demixing of Calcium Imaging Data Eftychios A. Pnevmatikakis, Daniel Soudry, Yuanjun Gao et al. · Neuron | 2016 | 1,205 |
| 41 | The neuronal architecture of the mushroom body provides a logic for associative learning Yoshinori Aso, Daisuke Hattori, Yang Yu et al. · eLife | 22 Dec 2014 | 1,194 |
| 42 | A Complete Electron Microscopy Volume of the Brain of Adult Drosophila melanogaster Zhihao Zheng et al. · Cell | Jul 2018 | 1,191 |
| 43 | AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training Yexica Aponte, Deniz Atasoy, Scott M. Sternson · Nature Neuroscience | 5 Jan 2011 | 1,189 |
| 44 | Applying systems-level spectral imaging and analysis to reveal the organelle interactome Alex M. Valm, Sarah Cohen, Wesley R. Legant et al. · Nature | 23 May 2017 | 1,180 |
| 45 | Rfam 12.0: updates to the RNA families database Eric P. Nawrocki, Sarah Burge, Alex Bateman et al. · Nucleic Acids Research | 11 Nov 2014 | 1,167 |
| 46 | Neuropixels 2.0: A miniaturized high-density probe for stable, long-term brain recordings Nicholas A. Steinmetz et al. · Science | 15 Apr 2021 | 1,165 |
| 47 | Sensitive red protein calcium indicators for imaging neural activity Hod Dana, Boaz Mohar, Yi Sun et al. · eLife | 24 Mar 2016 | 1,163 |
| 48 | Rapid three-dimensional isotropic imaging of living cells using Bessel beam plane illumination Thomas A. Planchon, Liang Gao, Daniel E. Milkie et al. · Nature Methods | 4 Mar 2011 | 1,150 |
| 49 | The subcellular organization of neocortical excitatory connections Leopoldo Petreanu, Tianyi Mao, Scott M. Sternson et al. · Nature | 18 Jan 2009 | 1,137 |
| 50 | A new generation of homology search tools based on probabilistic inference. Sean R. Eddy · PubMed | Oct 2009 | 1,116 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.