Institution · Japan Science and Technology Agency
Most cited papers from Japan Science and Technology Agency
What are the most cited papers from Japan Science and Technology Agency?
The most cited paper from Japan Science and Technology Agency is "Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors" (Kazutoshi Takahashi, Shinya Yamanaka, 2006), with 26,957 citations. Next come "Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors" (20,424) and "Pathogen Recognition and Innate Immunity" (12,064).
Showing 50 of 60 papers. Every paper with more than 2,409 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors Kazutoshi Takahashi, Shinya Yamanaka · Cell | Aug 2006 | 26,957 |
| 2 | Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors Kazutoshi Takahashi, Koji Tanabe, Mari Ohnuki et al. · Cell | Nov 2007 | 20,424 |
| 3 | Pathogen Recognition and Innate Immunity Shizuo Akira, Satoshi Uematsu, Osamu Takeuchi · Cell | Feb 2006 | 12,064 |
| 4 | Construction of Escherichia coli K‐12 in‐frame, single‐gene knockout mutants: the Keio collection Tomoya Baba, Takeshi Ara, Miki Launois Hasegawa et al. · Molecular Systems Biology | 21 Feb 2006 | 8,362 |
| 5 | Toll-like receptor signalling Shizuo Akira, Kiyoshi Takeda · Nature reviews. Immunology | 30 Jun 2004 | 8,340 |
| 6 | KEGG for linking genomes to life and the environment Minoru I. Kanehisa, Michihiro Araki, Susumu Goto et al. · Nucleic Acids Research | 12 Dec 2007 | 7,126 |
| 7 | LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing Yukihiro Kabeya, Noboru Mizushima, Takashi Ueno et al. · The EMBO Journal | Nov 2000 | 6,650 |
| 8 | A Toll-like receptor recognizes bacterial DNA Hiroaki Hemmi, Osamu Takeuchi, Taro Kawai et al. · Nature | 7 Dec 2000 | 6,498 |
| 9 | Superconductivity at 39 K in magnesium diboride Jun Nagamatsu, Norimasa Nakagawa, Takahiro Muranaka et al. · Nature | Mar 2001 | 6,487 |
| 10 | Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells Yukihiro Furusawa et al. · Nature | 13 Nov 2013 | 5,575 |
| 11 | Identification of the transforming EML4–ALK fusion gene in non-small-cell lung cancer Manabu Soda, Young Lim Choi, Munehiro Enomoto et al. · Nature | 11 Jul 2007 | 5,494 |
| 12 | Regulatory T Cells and Immune Tolerance Shimon Sakaguchi, Tomoyuki Yamaguchi, Takashi Nomura et al. · Cell | May 2008 | 5,393 |
| 13 | Increased oxidative stress in obesity and its impact on metabolic syndrome Shigetada Furukawa, Takuya Fujita, Michio Shimabukuro et al. · Journal of Clinical Investigation | 15 Dec 2004 | 5,349 |
| 14 | Protocol for micro-purification, enrichment, pre-fractionation and storage of peptides for proteomics using StageTips Juri Rappsilber, Matthias Mann, Yasushi Ishihama · Nature Protocols | Aug 2007 | 5,019 |
| 15 | Nanoionics-based resistive switching memories Rainer M. Waser, Masakazu Aono · Nature Materials | Nov 2007 | 4,903 |
| 16 | Toll-like receptors: critical proteins linking innate and acquired immunity Shizuo Akira, Kiyoshi Takeda, Tsuneyasu Kaisho · Nature Immunology | Aug 2001 | 4,814 |
| 17 | A high-mobility electron gas at the LaAlO3/SrTiO3 heterointerface Akira Ohtomo, Harold Y. Hwang · Nature | 28 Jan 2004 | 4,735 |
| 18 | Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria Ivaylo I. Ivanov, Koji Atarashi, Nicolas Manel et al. · Cell | Oct 2009 | 4,598 |
| 19 | Global Hydrological Cycles and World Water Resources Taikan Oki, Shinjiro Kanae · Science | 24 Aug 2006 | 4,472 |
| 20 | Global variation in copy number in the human genome Richard Redon et al. · Nature | Nov 2006 | 4,397 |
| 21 | Generation of germline-competent induced pluripotent stem cells Keisuke Okita, Tomoko Ichisaka, Shinya Yamanaka · Nature | 6 Jun 2007 | 4,268 |
| 22 | Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase Toshimasa Yamauchi, Junji Kamon, Yasuhiko Minokoshi et al. · Nature Medicine | 7 Oct 2002 | 4,251 |
| 23 | An Nrf2/Small Maf Heterodimer Mediates the Induction of Phase II Detoxifying Enzyme Genes through Antioxidant Response Elements Ken Itoh, Tomoki Chiba, Satoru Takahashi et al. · Biochemical and Biophysical Research Communications | Jul 1997 | 4,013 |
| 24 | Autophagy: process and function Noboru Mizushima · Genes & Development | 15 Nov 2007 | 4,008 |
| 25 | Species-Specific Recognition of Single-Stranded RNA via Toll-like Receptor 7 and 8 Florian Heil, Hiroaki Hemmi, Hubertus Hochrein et al. · Science | 23 Feb 2004 | 3,973 |
| 26 | Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses Hiroki Kato, Osamu Takeuchi, Shintaro Sato et al. · Nature | 9 Apr 2006 | 3,913 |
| 27 | Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice Taichi Hara, Kenji D. Nakamura, Makoto Matsui et al. · Nature | 19 Apr 2006 | 3,905 |
| 28 | The BDNF val66met Polymorphism Affects Activity-Dependent Secretion of BDNF and Human Memory and Hippocampal Function Michael F. Egan, Masami Kojima, Joseph H. Callicott et al. · Cell | 2003 | 3,902 |
| 29 | Photoluminescence from Chemically Exfoliated MoS 2 Goki Eda, Hisato Yamaguchi, Damien Voiry et al. · Nano Letters | 28 Oct 2011 | 3,868 |
| 30 | The repertoire of mutational signatures in human cancer Ludmil B. Alexandrov et al. · Nature | 5 Feb 2020 | 3,854 |
| 31 | Nano‐photocatalytic Materials: Possibilities and Challenges Hua Tong, Shuxin Ouyang, Yingpu Bi et al. · Advanced Materials | 4 Oct 2011 | 3,833 |
| 32 | Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species Koji Atarashi, Takeshi Tanoue, Tatsuichiro Shima et al. · Science | 23 Dec 2010 | 3,724 |
| 33 | MS-DIAL: data-independent MS/MS deconvolution for comprehensive metabolome analysis Hiroshi Tsugawa, Tomáš Čajka, Tobias Kind et al. · Nature Methods | 4 May 2015 | 3,549 |
| 34 | Bcl-2 Antiapoptotic Proteins Inhibit Beclin 1-Dependent Autophagy Sophie Pattingre, Amina Tassa, Xueping Qu et al. · Cell | Sep 2005 | 3,541 |
| 35 | Real-space observation of a two-dimensional skyrmion crystal Xiuzhen Yu, Y. Onose, Naoya Kanazawa et al. · Nature | Jun 2010 | 3,507 |
| 36 | Innate Antiviral Responses by Means of TLR7-Mediated Recognition of Single-Stranded RNA Sandra S. Diebold, Tsuneyasu Kaisho, Hiroaki Hemmi et al. · Science | 23 Feb 2004 | 3,453 |
| 37 | Differential Roles of TLR2 and TLR4 in Recognition of Gram-Negative and Gram-Positive Bacterial Cell Wall Components Osamu Takeuchi, Katsuaki Hoshino, Taro Kawai et al. · Immunity | Oct 1999 | 3,391 |
| 38 | Cutting Edge: Toll-Like Receptor 4 (TLR4)-Deficient Mice Are Hyporesponsive to Lipopolysaccharide: Evidence for TLR4 as the Lps Gene Product Katsuaki Hoshino, Osamu Takeuchi, Taro Kawai et al. · The Journal of Immunology | Apr 1999 | 3,391 |
| 39 | Pan-cancer analysis of whole genomes Lauri A. Aaltonen et al. · Nature | 5 Feb 2020 | 3,360 |
| 40 | Architecture of the Photosynthetic Oxygen-Evolving Center Kristina N. Ferreira, T.M. Iverson, Karim Maghlaoui et al. · Science | 9 Feb 2004 | 3,351 |
| 41 | Variational quantum algorithms M. Cerezo, Andrew Arrasmith, Ryan Babbush et al. · Nature Reviews Physics | 12 Aug 2021 | 3,280 |
| 42 | A stretchable carbon nanotube strain sensor for human-motion detection Takeo Yamada, Yuhei Hayamizu, Yuki Yamamoto et al. · Nature Nanotechnology | 27 Mar 2011 | 3,247 |
| 43 | Biogenesis of small RNAs in animals V. Narry Kim, Jinju Han, Mikiko C. Siomi · Nature Reviews Molecular Cell Biology | 23 Jan 2009 | 3,201 |
| 44 | Cloning of adiponectin receptors that mediate antidiabetic metabolic effects Toshimasa Yamauchi et al. · Nature | 11 Jun 2003 | 3,196 |
| 45 | Covalent organic frameworks Xiao Zhen Feng, Xuesong Ding, Donglin Jiang · Chemical Society Reviews | 2012 | 3,099 |
| 46 | TRANSCRIPTIONAL REGULATORY NETWORKS IN CELLULAR RESPONSES AND TOLERANCE TO DEHYDRATION AND COLD STRESSES Kazuko Yamaguchi‐Shinozaki, Kazuo Shinozaki · Annual Review of Plant Biology | 7 Apr 2006 | 3,044 |
| 47 | Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota Koji Atarashi et al. · Nature | 9 Jul 2013 | 2,965 |
| 48 | CTLA-4 Control over Foxp3 + Regulatory T Cell Function Kajsa Wing, Yasushi Onishi, Paz Prieto-Martin et al. · Science | 10 Oct 2008 | 2,938 |
| 49 | The role of autophagy during the early neonatal starvation period Akiko Kuma, Masahiko Hatano, Makoto Matsui et al. · Nature | 3 Nov 2004 | 2,878 |
| 50 | Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts Masato Nakagawa, Michiyo Koyanagi, Koji Tanabe et al. · Nature Biotechnology | 30 Nov 2007 | 2,802 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.