| 1 |
Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK
Merryn Voysey et al. · The Lancet
Open access765 authors |
8 Dec 2020 |
5,030 |
| 2 |
VaxiJen: a server for prediction of protective antigens, tumour antigens and subunit vaccines
Irini Atanas Doytchinova, Darren R. Flower · BMC Bioinformatics
Open access |
5 Jan 2007 |
3,092 |
| 3 |
Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial
Pedro M. Folegatti et al. · The Lancet
Open access365 authors |
20 Jul 2020 |
2,629 |
| 4 |
Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial
Maheshi N Ramasamy et al. · The Lancet
Open access421 authors |
19 Nov 2020 |
1,415 |
| 5 |
Efficacy of the ChAdOx1 nCoV-19 Covid-19 Vaccine against the B.1.351 Variant
Shabir Ahmed Madhi et al. · New England Journal of Medicine
Open access |
16 Mar 2021 |
1,322 |
| 6 |
Targeting bromodomains: epigenetic readers of lysine acetylation
P. Filippakopoulos, Stefan Knapp · Nature Reviews Drug Discovery
Review |
22 Apr 2014 |
1,267 |
| 7 |
Correlates of protection against symptomatic and asymptomatic SARS-CoV-2 infection
Shuo Feng et al. · Nature Medicine
Open access |
29 Sep 2021 |
1,247 |
| 8 |
Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials
Merryn Voysey et al. · The Lancet
Open access766 authors |
21 Feb 2021 |
1,213 |
| 9 |
Evidence of escape of SARS-CoV-2 variant B.1.351 from natural and vaccine-induced sera
Daming Zhou et al. · Cell
Open access |
23 Feb 2021 |
1,157 |
| 10 |
Safety and efficacy of MVA85A, a new tuberculosis vaccine, in infants previously vaccinated with BCG: a randomised, placebo-controlled phase 2b trial
Michele D. Tameris, Mark Hatherill, Bernard Landry et al. · The Lancet
Open access |
4 Feb 2013 |
1,060 |
| 11 |
SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses
Wanwisa Dejnirattisai et al. · Cell
Open access466 authors |
3 Jan 2022 |
1,027 |
| 12 |
Dectin-1 Is A Major β-Glucan Receptor On Macrophages
Gordon D. Brown, Philip R. Taylor, Delyth M. Reid et al. · The Journal of Experimental Medicine
Open access |
29 Jul 2002 |
1,018 |
| 13 |
ChAdOx1 nCoV-19 vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques
Neeltje van Doremalen et al. · Nature
Open access |
30 Jul 2020 |
992 |
| 14 |
Type I Interferons Potently Enhance Humoral Immunity and Can Promote Isotype Switching by Stimulating Dendritic Cells In Vivo
Agnès Le Bon, Giovanna Schiavoni, Giuseppina D’Agostino et al. · Immunity
Open access |
Apr 2001 |
974 |
| 15 |
Incorporating outlier detection and replacement into a non-parametric framework for movement and distortion correction of diffusion MR images
Jesper Andersson, Mark S. Graham, Enikő Zsoldos et al. · NeuroImage
Open access |
6 Jul 2016 |
882 |
| 16 |
The lipocalin protein family: structural and sequence overview
Darren R. Flower, Anthony C.T. North, Clare Sansom · Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology
|
Oct 2000 |
877 |
| 17 |
The immune response during acute HIV-1 infection: clues for vaccine development
Andrew James McMichael, Persephone Borrow, Georgia D. Tomaras et al. · Nature reviews. Immunology
ReviewOpen access |
11 Dec 2009 |
874 |
| 18 |
COVID-19 vaccine hesitancy in the UK: the Oxford coronavirus explanations, attitudes, and narratives survey (Oceans) II
Daniel H. Freeman, Bao Sheng Loe, Andrew T. Chadwick et al. · Psychological Medicine
Open access |
11 Dec 2020 |
816 |
| 19 |
Cross-priming of CD8+ T cells stimulated by virus-induced type I interferon
Agnès Le Bon, Nathalie Etchart, Cornelia Rossmann et al. · Nature Immunology
|
21 Sep 2003 |
812 |
| 20 |
Induction of a Striking Systemic Cytokine Cascade prior to Peak Viremia in Acute Human Immunodeficiency Virus Type 1 Infection, in Contrast to More Modest and Delayed Responses in Acute Hepatitis B and C Virus Infections
Andrea Stacey, Philip J. Norris, Qin Li et al. · Journal of Virology
Open access |
28 Jan 2009 |
766 |
| 21 |
Reduced neutralization of SARS-CoV-2 B.1.617 by vaccine and convalescent serum
Chang Liu et al. · Cell
Open access |
17 Jun 2021 |
752 |
| 22 |
Safety and immunogenicity of seven COVID-19 vaccines as a third dose (booster) following two doses of ChAdOx1 nCov-19 or BNT162b2 in the UK (COV-BOOST): a blinded, multicentre, randomised, controlled, phase 2 trial
Alasdair P S Munro et al. · The Lancet
Open access308 authors |
Dec 2021 |
699 |
| 23 |
What defines an efficacious COVID-19 vaccine? A review of the challenges assessing the clinical efficacy of vaccines against SARS-CoV-2
Susanne H. C. Hodgson, Kushal Mansatta, Garry Mallett et al. · The Lancet Infectious Diseases
Open access |
27 Oct 2020 |
673 |
| 24 |
Antibody evasion by the P.1 strain of SARS-CoV-2
Wanwisa Dejnirattisai et al. · Cell
Open access |
30 Mar 2021 |
661 |
| 25 |
The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection
Nilu P Goonetilleke et al. · The Journal of Experimental Medicine
Open access |
Jun 2009 |
655 |
| 26 |
Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 variant of concern 202012/01 (B.1.1.7): an exploratory analysis of a randomised controlled trial
Katherine R. W. Emary et al. · The Lancet
Open access |
30 Mar 2021 |
652 |
| 27 |
The β-Glucan Receptor, Dectin-1, Is Predominantly Expressed on the Surface of Cells of the Monocyte/Macrophage and Neutrophil Lineages
Philip R. Taylor, Gordon D. Brown, Delyth M. Reid et al. · The Journal of Immunology
Open access |
Oct 2002 |
651 |
| 28 |
T cell and antibody responses induced by a single dose of ChAdOx1 nCoV-19 (AZD1222) vaccine in a phase 1/2 clinical trial
Katie Ewer et al. · Nature Medicine
Open access284 authors |
17 Dec 2020 |
646 |
| 29 |
The biology of platelet-rich plasma and its application in trauma and orthopaedic surgery
Joseph Alsousou, Mark S. Thompson, P A Hulley et al. · Journal of Bone and Joint Surgery - British Volume
Open access |
Aug 2009 |
600 |
| 30 |
Links between innate and adaptive immunity via type I interferon
Agnès Le Bon, David F. Tough · Current Opinion in Immunology
Review |
Aug 2002 |
588 |
| 31 |
Viral infection switches non-plasmacytoid dendritic cells into high interferon producers
Sandra S. Diebold, María Montoya, Hermann Unger et al. · Nature
|
22 Jun 2003 |
580 |
| 32 |
Major findings and recent advances in virus–like particle (VLP)-based vaccines
Mona Omar Mohsen, Lisha Zha, Gustavo Cabral‐Miranda et al. · Seminars in Immunology
|
5 Sep 2017 |
571 |
| 33 |
Safety and immunogenicity of heterologous versus homologous prime-boost schedules with an adenoviral vectored and mRNA COVID-19 vaccine (Com-COV): a single-blind, randomised, non-inferiority trial
Xinxue Liu et al. · The Lancet
Open access |
6 Aug 2021 |
552 |
| 34 |
Natural History, Quality of Life, and Outcome in Cardiac Transthyretin Amyloidosis
Thirusha Lane et al. · Circulation
Open access |
21 May 2019 |
542 |
| 35 |
Reduced neutralization of SARS-CoV-2 B.1.1.7 variant by convalescent and vaccine sera
Piyada Supasa et al. · Cell
Open access |
18 Feb 2021 |
529 |
| 36 |
Human CD4+ CD25hi Foxp3+ regulatory T cells are derived by rapid turnover of memory populations in vivo
Milica Vukmanovic‐Stejic, Yan Zhang, Joanne E. Cook et al. · Journal of Clinical Investigation
Open access |
Sep 2006 |
491 |
| 37 |
Maintaining protection against invasive bacteria with protein–polysaccharide conjugate vaccines
Andrew John Pollard, Kirsten P. Perrett, Peter C. L. Beverley · Nature reviews. Immunology
Review |
13 Feb 2009 |
487 |
| 38 |
Comprehensive, Quantitative Mapping of T Cell Epitopes in Gluten in Celiac Disease
Jason A. Tye–Din, Jessica A. Stewart, James A. Dromey et al. · Science Translational Medicine
|
21 Jul 2010 |
476 |
| 39 |
Efficacy of a low-dose candidate malaria vaccine, R21 in adjuvant Matrix-M, with seasonal administration to children in Burkina Faso: a randomised controlled trial
Mehreen S. Datoo et al. · The Lancet
Open access |
May 2021 |
473 |
| 40 |
Initial T cell frequency dictates memory CD8+ T cell lineage commitment
Amanda Lee Marzo, Kimberly D. Klonowski, Agnès Le Bon et al. · Nature Immunology
Open access |
17 Jul 2005 |
468 |
| 41 |
Emerging COVID-19 variants and their impact on SARS-CoV-2 diagnosis, therapeutics and vaccines
Queenie Fernandes, Varghese Philipose Inchakalody, Maysaloun Merhi et al. · Annals of Medicine
Open access |
8 Feb 2022 |
462 |
| 42 |
IL-15 Is Expressed by Dendritic Cells in Response to Type I IFN, Double-Stranded RNA, or Lipopolysaccharide and Promotes Dendritic Cell Activation
Fabrizio Mattei, Giovanna Schiavoni, Filippo Belardelli et al. · The Journal of Immunology
Open access |
Aug 2001 |
458 |
| 43 |
Developmental kinetics and lifespan of dendritic cells in mouse lymphoid organs
Arun T. Kamath, Sandrine Henri, Frank L. Battye et al. · Blood
|
Sep 2002 |
455 |
| 44 |
On Iron Metabolism and Its Regulation
Anne‐Cathrine S. Vogt, Tasneem Arsiwala, Mona Omar Mohsen et al. · International Journal of Molecular Sciences
Open access |
27 Apr 2021 |
453 |
| 45 |
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond
Wesley C. Van Voorhis et al. · PLoS Pathogens
Open access187 authors |
28 Jul 2016 |
452 |
| 46 |
Safety and immunogenicity of seven COVID-19 vaccines as a third dose (booster) following two doses of ChAdOx1 nCov-19 or BNT162b2 in the UK (COV-BOOST): a blinded, multicentre, randomised, controlled, phase 2 trial
Munro, APS et al. · Sussex Research Online (University of Sussex)
Open access |
2 Dec 2021 |
445 |
| 47 |
Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank
Louise V. Wain et al. · The Lancet Respiratory Medicine
Open access |
28 Sep 2015 |
441 |
| 48 |
Plug-and-Display: decoration of Virus-Like Particles via isopeptide bonds for modular immunization
Karl D. Brune, Darren B. Leneghan, Iona J. Brian et al. · Scientific Reports
Open access |
19 Jan 2016 |
440 |
| 49 |
Towards a comprehensive framework for movement and distortion correction of diffusion MR images: Within volume movement
Jesper Andersson, Mark S. Graham, Ivana Drobnjak et al. · NeuroImage
Open access |
8 Mar 2017 |
436 |
| 50 |
Cytokines induced during chronic hepatitis B virus infection promote a pathway for NK cell–mediated liver damage
Claire Dunn, Maurizia Rossana Brunetto, Gary M. Reynolds et al. · The Journal of Experimental Medicine
Open access |
12 Mar 2007 |
425 |