| 1 |
Early versus Late Parenteral Nutrition in Critically Ill Adults
Michael Paul Casaer, Dieter Mesotten, Greet Hermans et al. · New England Journal of Medicine
Open access |
29 Jun 2011 |
1,704 |
| 2 |
Radial versus femoral access in patients with acute coronary syndromes undergoing invasive management: a randomised multicentre trial
Marco Valgimigli et al. · The Lancet
Open access |
18 Mar 2015 |
1,311 |
| 3 |
The future of cystic fibrosis care: a global perspective
Scott C Bell et al. · The Lancet Respiratory Medicine
Open access |
27 Sep 2019 |
988 |
| 4 |
Secondary prevention through comprehensive cardiovascular rehabilitation: From knowledge to implementation. 2020 update. A position paper from the Secondary Prevention and Rehabilitation Section of the European Association of Preventive Cardiology
Marco Ambrosetti et al. · European Journal of Preventive Cardiology
Open access |
30 Mar 2020 |
973 |
| 5 |
Ticagrelor plus aspirin for 1 month, followed by ticagrelor monotherapy for 23 months vs aspirin plus clopidogrel or ticagrelor for 12 months, followed by aspirin monotherapy for 12 months after implantation of a drug-eluting stent: a multicentre, open-label, randomised superiority trial
Pascal Vranckx et al. · The Lancet
Open access203 authors |
27 Aug 2018 |
797 |
| 6 |
Edoxaban-based versus vitamin K antagonist-based antithrombotic regimen after successful coronary stenting in patients with atrial fibrillation (ENTRUST-AF PCI): a randomised, open-label, phase 3b trial
Pascal Vranckx, Marco Valgimigli, Lars Eckardt et al. · The Lancet
|
3 Sep 2019 |
685 |
| 7 |
Secondary prevention in the clinical management of patients with cardiovascular diseases. Core components, standards and outcome measures for referral and delivery
Massimo Francesco Piepoli, Ugo Corrà, Stamatis N. Adamopoulos et al. · European Journal of Preventive Cardiology
Open access |
20 Jun 2012 |
604 |
| 8 |
Dual Antiplatelet Therapy after PCI in Patients at High Bleeding Risk
Marco Valgimigli et al. · New England Journal of Medicine
Open access |
28 Aug 2021 |
589 |
| 9 |
Focal Boost to the Intraprostatic Tumor in External Beam Radiotherapy for Patients With Localized Prostate Cancer: Results From the FLAME Randomized Phase III Trial
Linda G.W. Kerkmeijer, Veerle H. Groen, Floris J. Pos et al. · Journal of Clinical Oncology
Open access |
20 Jan 2021 |
538 |
| 10 |
36th International Symposium on Intensive Care and Emergency Medicine
R. M. Bateman et al. · Critical Care
Open access2,440 authors |
Apr 2016 |
531 |
| 11 |
Canakinumab for the Treatment of Autoinflammatory Recurrent Fever Syndromes
Fabrizio De Benedetti et al. · New England Journal of Medicine
Open access |
16 May 2018 |
489 |
| 12 |
Safety of pulsed field ablation in more than 17,000 patients with atrial fibrillation in the MANIFEST-17K study
Emmanuel Ekanem et al. · Nature Medicine
Open access139 authors |
Jul 2024 |
484 |
| 13 |
Reduced Cortisol Metabolism during Critical Illness
Eva Boonen, Hilke B.V.K. Vervenne, Philippe Meersseman et al. · New England Journal of Medicine
Open access |
19 Mar 2013 |
483 |
| 14 |
Uninterrupted rivaroxaban vs. uninterrupted vitamin K antagonists for catheter ablation in non-valvular atrial fibrillation
Riccardo Cappato, Francis E. Marchlinski, Stefan Hans Hohnloser et al. · European Heart Journal
Open access |
14 May 2015 |
431 |
| 15 |
Bivalirudin or Unfractionated Heparin in Acute Coronary Syndromes
Marco Valgimigli et al. · New England Journal of Medicine
Open access |
Sep 2015 |
398 |
| 16 |
Free serum concentrations of the protein-bound retention solute p-cresol predict mortality in hemodialysis patients
Bert Bammens, Pieter Evenepoel, H. Keuleers et al. · Kidney International
Open access |
18 Jan 2006 |
386 |
| 17 |
Safety and Effectiveness of Pulsed Field Ablation to Treat Atrial Fibrillation: One-Year Outcomes From the MANIFEST-PF Registry
Mohit K. Turagam et al. · Circulation
Open access |
18 May 2023 |
378 |
| 18 |
Skeletal Muscle Hypertrophy Following Resistance Training Is Accompanied by a Fiber Type-Specific Increase in Satellite Cell Content in Elderly Men
Lex B. Verdijk, Benjamin G. Gleeson, Richard A. M. Jonkers et al. · The Journals of Gerontology Series A
Open access |
5 Feb 2009 |
374 |
| 19 |
European Association of Preventive Cardiology (EAPC) and European Association of Cardiovascular Imaging (EACVI) joint position statement: recommendations for the indication and interpretation of cardiovascular imaging in the evaluation of the athlete’s heart
Antonio Pelliccia et al. · European Heart Journal
Open access |
23 Aug 2017 |
370 |
| 20 |
Compromised CD4+ CD25high regulatory T‐cell function in patients with relapsing‐remitting multiple sclerosis is correlated with a reduced frequency of FOXP3‐positive cells and reduced FOXP3 expression at the single‐cell level
Koen Venken, Niels Hellings, Marielle M. Thewissen et al. · Immunology
Open access |
26 Sep 2007 |
362 |
| 21 |
Multi-national survey on the methods, efficacy, and safety on the post-approval clinical use of pulsed field ablation (MANIFEST-PF)
Emmanuel Ekanem et al. · EP Europace
Open access |
14 Apr 2022 |
353 |
| 22 |
Effects of Infant Formula With Human Milk Oligosaccharides on Growth and Morbidity
Giuseppe Puccio, Philippe Alliet, Cinzia Cajozzo et al. · Journal of Pediatric Gastroenterology and Nutrition
Open access |
21 Jan 2017 |
349 |
| 23 |
Comparison of tiotropium once daily, formoterol twice daily and both combined once daily in patients with COPD
Jan Arie van Noord, J-L. Aumann, Wim Janssens et al. · European Respiratory Journal
Open access |
29 Jul 2005 |
341 |
| 24 |
ESC e-Cardiology Working Group Position Paper: Overcoming challenges in digital health implementation in cardiovascular medicine
Ines Frederix et al. · European Journal of Preventive Cardiology
Open access |
28 Mar 2019 |
334 |
| 25 |
Report from the European Myeloma Network on interphase FISH in multiple myeloma and related disorders
F. M. Ross et al. · Haematologica
Open access |
27 Feb 2012 |
327 |
| 26 |
Exercise intensity assessment and prescription in cardiovascular rehabilitation and beyond: why and how: a position statement from the Secondary Prevention and Rehabilitation Section of the European Association of Preventive Cardiology
Dominique Hansen, Ana Abreu, Marco Ambrosetti et al. · European Journal of Preventive Cardiology
Open access |
9 Jan 2021 |
319 |
| 27 |
Safety and efficacy outcomes of double vs. triple antithrombotic therapy in patients with atrial fibrillation following percutaneous coronary intervention: a systematic review and meta-analysis of non-vitamin K antagonist oral anticoagulant-based randomized clinical trials
Giuseppe Gargiulo, Andreas Goette, Jan G.P. Tijssen et al. · European Heart Journal
ReviewOpen access |
3 Oct 2019 |
318 |
| 28 |
Free p-cresol is associated with cardiovascular disease in hemodialysis patients
Björn K.I. Meijers, Bert Bammens, Bart De Moor et al. · Kidney International
Open access |
27 Feb 2008 |
314 |
| 29 |
Accuracy in Diagnosis of Celiac Disease Without Biopsies in Clinical Practice
Katharina Julia Werkstetter et al. · Gastroenterology
Open access |
15 Jun 2017 |
311 |
| 30 |
Radial versus femoral access and bivalirudin versus unfractionated heparin in invasively managed patients with acute coronary syndrome (MATRIX): final 1-year results of a multicentre, randomised controlled trial
Marco Valgimigli et al. · The Lancet
108 authors |
25 Aug 2018 |
309 |
| 31 |
Pulmonary Vein Isolation With Very High Power, Short Duration, Temperature-Controlled Lesions
Vivek Yerrapu Reddy, Massimo Grimaldi, Tom J. R. De Potter et al. · JACC. Clinical electrophysiology
Open access |
8 May 2019 |
299 |
| 32 |
Spinal cord stimulation in patients with painful diabetic neuropathy: A multicentre randomized clinical trial
Cecile C. de Vos, Kaare Meier, Paul Brocades Zaalberg et al. · Pain
|
29 Aug 2014 |
288 |
| 33 |
Genetic and Transcriptomic Bases of Intestinal Epithelial Barrier Dysfunction in Inflammatory Bowel Disease
Maaike Vancamelbeke, Tim Vanuytsel, Ricard Farré et al. · Inflammatory Bowel Diseases
Open access |
7 Sep 2017 |
272 |
| 34 |
The t(8;9)(p22;p24) Is a Recurrent Abnormality in Chronic and Acute Leukemia that Fuses PCM1 to JAK2
Andreas Reiter et al. · Cancer Research
|
Apr 2005 |
266 |
| 35 |
Long-term leucine supplementation does not increase muscle mass or strength in healthy elderly men
Suzanne Verhoeven, Kristof Vanschoonbeek, Lex B. Verdijk et al. · American Journal of Clinical Nutrition
Open access |
26 Mar 2009 |
266 |
| 36 |
The future is now: a call for action for cardiac telerehabilitation in the COVID-19 pandemic from the secondary prevention and rehabilitation section of the European Association of Preventive Cardiology
Martijn Scherrenberg, Matthias Wilhelm, Dominique Hansen et al. · European Journal of Preventive Cardiology
Open access |
3 Jul 2020 |
264 |
| 37 |
Natural Naive CD4+CD25+CD127low Regulatory T Cell (Treg) Development and Function Are Disturbed in Multiple Sclerosis Patients: Recovery of Memory Treg Homeostasis during Disease Progression
Koen Venken, Niels Hellings, Tom Broekmans et al. · The Journal of Immunology
Open access |
May 2008 |
262 |
| 38 |
P2Y12 inhibitor monotherapy or dual antiplatelet therapy after coronary revascularisation: individual patient level meta-analysis of randomised controlled trials
Marco Valgimigli et al. · BMJ
ReviewOpen access |
16 Jun 2021 |
261 |
| 39 |
Artificial intelligence outperforms pulmonologists in the interpretation of pulmonary function tests
Marko Topalovic, Nilakash Das, Pierre‐Régis Burgel et al. · European Respiratory Journal
Open access |
14 Feb 2019 |
251 |
| 40 |
Effect of a Telemonitoring-Facilitated Collaboration Between General Practitioner and Heart Failure Clinic on Mortality and Rehospitalization Rates in Severe Heart Failure: The TEMA-HF 1 (Telemonitoring in the Management of Heart Failure) Study
Paul Dendale, Gilles W. De Keulenaer, Pierre Troisfontaines et al. · European Journal of Heart Failure
Open access |
Nov 2011 |
251 |
| 41 |
Abdominal subcutaneous and visceral adipocyte size, lipolysis and inflammation relate to insulin resistance in male obese humans
Kenneth Verboven, Kristiaan Wouters, Katrien H.J. Gaens et al. · Scientific Reports
Open access |
12 Mar 2018 |
249 |
| 42 |
Apixaban in patients at risk of stroke undergoing atrial fibrillation ablation
Paulus F. Kirchhof et al. · European Heart Journal
Open access |
16 Mar 2018 |
246 |
| 43 |
Whole-body MRI with diffusion-weighted sequence for staging of patients with suspected ovarian cancer: a clinical feasibility study in comparison to CT and FDG-PET/CT
Katrijn Michielsen, Ignace B. Vergote, Katya Op de beeck et al. · European Radiology
|
9 Dec 2013 |
238 |
| 44 |
Recovery of Regional but Not Global Contractile Function by the Direct Intramyocardial Autologous Bone Marrow Transplantation
Marc Hendrikx, Karen Hensen, Christel Clijsters et al. · Circulation
Open access |
4 Jul 2006 |
237 |
| 45 |
Paroxysmal Atrial Fibrillation Ablation Using a Novel Variable-Loop Biphasic Pulsed Field Ablation Catheter Integrated With a 3-Dimensional Mapping System: 1-Year Outcomes of the Multicenter inspIRE Study
Mattias Francis Duytschaever et al. · Circulation Arrhythmia and Electrophysiology
Open access |
3 Feb 2023 |
232 |
| 46 |
Incidence and outcome of inappropriate in-hospital empiric antibiotics for severe infection: a systematic review and meta-analysis
Kristel Marquet, An Liesenborgs, Jochen Bergs et al. · Critical Care
ReviewOpen access |
17 Feb 2015 |
215 |
| 47 |
Impact of COVID-19 Pandemic on Mechanical Reperfusion for Patients With STEMI
Giuseppe De Luca et al. · Journal of the American College of Cardiology
Open access |
Nov 2020 |
210 |
| 48 |
A review of telerehabilitation for cardiac patients
Ines Frederix, Luc Vanhees, Paul Dendale et al. · Journal of Telemedicine and Telecare
Open access |
4 Dec 2014 |
206 |
| 49 |
Effect of vedolizumab (anti-α4β7-integrin) therapy on histological healing and mucosal gene expression in patients with UC
Ingrid Arijs, Gert D. Hertogh, Bart Lemmens et al. · Gut
Open access |
7 Oct 2016 |
202 |
| 50 |
Exercise Prescription in Patients with Different Combinations of Cardiovascular Disease Risk Factors: A Consensus Statement from the EXPERT Working Group
Dominique Hansen et al. · Sports Medicine
Open access |
4 May 2018 |
201 |