Institution · Joint Center for Structural Genomics
Most cited papers from Joint Center for Structural Genomics
What are the most cited papers from Joint Center for Structural Genomics?
The most cited paper from Joint Center for Structural Genomics is "The mutational constraint spectrum quantified from variation in 141,456 humans" (Konrad J. Karczewski et al., 2020), with 10,422 citations. Next come "An integrated map of genetic variation from 1,092 human genomes" (8,281) and "Targeting the tumor microenvironment: removing obstruction to anticancer immune responses and immunotherapy" (1,406).
Showing 50 of 60 papers. Every paper with more than 209 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | The mutational constraint spectrum quantified from variation in 141,456 humans Konrad J. Karczewski et al. · Nature | 27 May 2020 | 10,422 |
| 2 | An integrated map of genetic variation from 1,092 human genomes Gil A. McVean et al. · Nature | 31 Oct 2012 | 8,281 |
| 3 | Targeting the tumor microenvironment: removing obstruction to anticancer immune responses and immunotherapy Jonathan M. Pitt, Aurélien Marabelle, Alexander M.M. Eggermont et al. · Annals of Oncology | 11 Apr 2016 | 1,406 |
| 4 | Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects Christian R. Marshall et al. · Nature Genetics | 21 Nov 2016 | 1,160 |
| 5 | A Virulence Locus of Pseudomonas aeruginosa Encodes a Protein Secretion Apparatus Joseph D. Mougous, M.E. Cuff, Stefan Raunser et al. · Science | 8 Jun 2006 | 1,135 |
| 6 | A lipidome atlas in MS-DIAL 4 Hiroshi Tsugawa et al. · Nature Biotechnology | 15 Jun 2020 | 926 |
| 7 | Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser Yanyong Kang et al. · Nature | 22 Jul 2015 | 845 |
| 8 | Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer Jean‐Philippe Julien, Albert Cupo, Devin Sok et al. · Science | Nov 2013 | 836 |
| 9 | Definition and description of schizophrenia in the DSM-5 Rajiv Tandon, Wolfgang Gäebel, Deanna M. Barch et al. · Schizophrenia Research | 22 Jun 2013 | 821 |
| 10 | Accessing protein conformational ensembles using room-temperature X-ray crystallography James S. Fraser, Henry van den Bedem, Avi J. Samelson et al. · Proceedings of the National Academy of Sciences | 14 Sep 2011 | 663 |
| 11 | Intestinal inflammation allows Salmonella to use ethanolamine to compete with the microbiota Parameth Thiennimitr, Sebastian Winter, Maria G. Winter et al. · Proceedings of the National Academy of Sciences | 3 Oct 2011 | 642 |
| 12 | Metabolomics enables precision medicine: “A White Paper, Community Perspective” for “Precision Medicine and Pharmacometabolomics Task Group”-Metabolomics Societ, Richard D. Beger, Warwick B. Dunn et al. · Metabolomics | Sep 2016 | 624 |
| 13 | Structural plasticity of SARS-CoV-2 3CL Mpro active site cavity revealed by room temperature X-ray crystallography Daniel W. Kneller, G.N. Phillips, Hugh O’Neill et al. · Nature Communications | 24 Jun 2020 | 510 |
| 14 | Identification of small molecules using accurate mass MS/MS search Tobias Kind, Hiroshi Tsugawa, Tomáš Čajka et al. · Mass Spectrometry Reviews | 24 Apr 2017 | 492 |
| 15 | Structure of papain-like protease from SARS-CoV-2 and its complexes with non-covalent inhibitors J. Osipiuk et al. · Nature Communications | 2 Feb 2021 | 474 |
| 16 | Integrating sequence and array data to create an improved 1000 Genomes Project haplotype reference panel Olivier Delaneau et al. · Nature Communications | 13 Jun 2014 | 459 |
| 17 | New mini- zincin structures provide a minimal scaffold for members of this metallopeptidase superfamily Christine B. Trame, Yuanyuan Chang, Herbert L. Axelrod et al. · BMC Bioinformatics | 3 Jan 2014 | 432 |
| 18 | OrfPredictor: predicting protein-coding regions in EST-derived sequences Xiang Jia Min, Gregory Butler, Reginald K. Storms et al. · Nucleic Acids Research | 26 Jun 2005 | 419 |
| 19 | Structure of the Angiotensin Receptor Revealed by Serial Femtosecond Crystallography Haitao Zhang et al. · Cell | 25 Apr 2015 | 393 |
| 20 | Chemical Similarity Enrichment Analysis (ChemRICH) as alternative to biochemical pathway mapping for metabolomic datasets Dinesh Kumar Barupal, Oliver Fiehn · Scientific Reports | 31 Oct 2017 | 387 |
| 21 | Molecular mechanisms of vancomycin resistance P.J. Stogios, Alexei V. Savchenko · Protein Science | 3 Jan 2020 | 383 |
| 22 | Structure of the human glucagon class B G-protein-coupled receptor Fai Siu, Min He, Chris de Graaf et al. · Nature | Jul 2013 | 381 |
| 23 | Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline Scott A. Lesley et al. · Proceedings of the National Academy of Sciences | 22 Aug 2002 | 377 |
| 24 | Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism Yuequan Shen, A. Joachimiak, Marsha Rich Rosner et al. · Nature | Oct 2006 | 377 |
| 25 | Crystal structure of Nsp15 endoribonuclease NendoU from SARS‐CoV ‐2 Youngchang Kim, Robert P. Jedrzejczak, Natalia Ivanovna Maltseva et al. · Protein Science | 18 Apr 2020 | 370 |
| 26 | Identification of Amino Acid Residues in the Capsid Proteins of Adeno-Associated Virus Type 2 That Contribute to Heparan Sulfate Proteoglycan Binding Shaun R. Opie, Kenneth H. Warrington, Mavis Agbandje‐McKenna et al. · Journal of Virology | 27 May 2003 | 363 |
| 27 | Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120 Leopold Kong et al. · Nature Structural & Molecular Biology | 26 May 2013 | 352 |
| 28 | Structure of the apoptotic protease-activating factor 1 bound to ADP Stefan J. Riedl, Wenyu Li, Chao Yang et al. · Nature | Apr 2005 | 346 |
| 29 | Duplications of the neuropeptide receptor gene VIPR2 confer significant risk for schizophrenia Vladimir Vacic et al. · Nature | 23 Feb 2011 | 341 |
| 30 | Protein crystallography for non‐crystallographers, or how to get the best (but not more) from published macromolecular structures Alexander Wlodawer, Wladek Minor, Zbigniew Dauter et al. · FEBS Journal | 27 Nov 2007 | 331 |
| 31 | Legume genome evolution viewed through the Medicago truncatula and Lotus japonicus genomes Steven B. Cannon et al. · Proceedings of the National Academy of Sciences | 26 Sep 2006 | 323 |
| 32 | Variants of DENND1B Associated with Asthma in Children Patrick M. A. Sleiman et al. · New England Journal of Medicine | 24 Dec 2009 | 321 |
| 33 | Data mining of metal ion environments present in protein structures Heping Zheng, M. Chruszcz, Piotr Lasota et al. · Journal of Inorganic Biochemistry | 29 May 2008 | 320 |
| 34 | Pseudo nucleotide composition or PseKNC: an effective formulation for analyzing genomic sequences Wei Chen, Hao Lin, Kuo‐Chen Chou · Molecular BioSystems | 5 Jun 2015 | 315 |
| 35 | Crystal structure of the tetramerization domain of the Shaker potassium channel Andreas Kreusch, Paul J. Pfaffinger, Charles F. Stevens et al. · Nature | Apr 1998 | 313 |
| 36 | North American Prodrome Longitudinal Study: A Collaborative Multisite Approach to Prodromal Schizophrenia Research J. Addington, Kristin S. Cadenhead, T. D. Cannon et al. · Schizophrenia Bulletin | 25 Jan 2007 | 304 |
| 37 | XtalPred: a web server for prediction of protein crystallizability Lukasz Slabinski, Lukasz Jaroszewski, Leszek Rychlewski et al. · Bioinformatics | 5 Oct 2007 | 303 |
| 38 | Combining the polymerase incomplete primer extension method for cloning and mutagenesis with microscreening to accelerate structural genomics efforts Heath E. Klock, Eric Koesema, Mark W. Knuth et al. · Proteins Structure Function and Bioinformatics | 14 Nov 2007 | 292 |
| 39 | HMGA2/TET1/HOXA9 signaling pathway regulates breast cancer growth and metastasis Miao Sun, Chun‐Xiao Song, Hao Huang et al. · Proceedings of the National Academy of Sciences | 28 May 2013 | 292 |
| 40 | Meta-analysis of 32 genome-wide linkage studies of schizophrenia Mandy Ng et al. · Molecular Psychiatry | 30 Dec 2008 | 282 |
| 41 | Crystal structure of the polymerase PAC–PB1N complex from an avian influenza H5N1 virus Xiaojing He, Jie Zhou, Mark G. Bartlam et al. · Nature | 9 Jul 2008 | 278 |
| 42 | Experimental and Computational Assessment of Conditionally Essential Genes inEscherichia coli Andrew R. Joyce, Jennifer L. Reed, Aprilfawn White et al. · Journal of Bacteriology | 16 Nov 2006 | 275 |
| 43 | Integrative, dynamic structural biology at atomic resolution—it's about time Henry van den Bedem, James S. Fraser · Nature Methods | 31 Mar 2015 | 273 |
| 44 | Arabidopsis Isochorismate Synthase Functional in Pathogen-induced Salicylate Biosynthesis Exhibits Properties Consistent with a Role in Diverse Stress Responses Marcus A. Strawn, Sharon K. Marr, Kentaro Inoue et al. · Journal of Biological Chemistry | 27 Dec 2006 | 266 |
| 45 | Crystal structure of the CorA Mg2+ transporter Vladimir V. Lunin, E. Dobrovetsky, Galina Khutoreskaya et al. · Nature | Apr 2006 | 262 |
| 46 | Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2 Nir Drayman et al. · Science | 20 Jul 2021 | 260 |
| 47 | Improved molecular replacement by density- and energy-guided protein structure optimization Frank DiMaio, Thomas C. Terwilliger, Randy J. Read et al. · Nature | 28 Apr 2011 | 252 |
| 48 | Machine learning reveals serum sphingolipids as cholesterol-independent biomarkers of coronary artery disease Annelise M. Poss, J. Alan Maschek, James Eric Cox et al. · Journal of Clinical Investigation | 19 Nov 2019 | 251 |
| 49 | Catatonia in DSM-5 Rajiv Tandon, Stephan Heckers, Juan Bustillo et al. · Schizophrenia Research | 25 Jun 2013 | 250 |
| 50 | Genetic and environmental influences on the size of specific brain regions in midlife: The VETSA MRI study William S. Kremen, Elizabeth C. Prom‐Wormley, Matthew S. Panizzon et al. · NeuroImage | 27 Sep 2009 | 246 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.