Most cited papers from KAN Research Institute
What are the most cited papers from KAN Research Institute?
The most cited paper from KAN Research Institute is "Size-selective loosening of the blood-brain barrier in claudin-5–deficient mice" (Takehiro Nitta, Masaki Hata, Shimpei Gotoh et al., 2003), with 1,942 citations. Next come "Claudin-based tight junctions are crucial for the mammalian epidermal barrier" (1,515) and "Genome sequencing and analysis of Aspergillus oryzae" (1,272).
Showing 50 of 60 papers. Every paper with more than 130 citations is listed.
| # | Paper | ||
|---|---|---|---|
| 1 | Size-selective loosening of the blood-brain barrier in claudin-5–deficient mice Takehiro Nitta, Masaki Hata, Shimpei Gotoh et al. · The Journal of Cell Biology | 12 May 2003 | 1,942 |
| 2 | Claudin-based tight junctions are crucial for the mammalian epidermal barrier Mikio Furuse, Masaki Hata, Kyoko Furuse et al. · The Journal of Cell Biology | 11 Mar 2002 | 1,515 |
| 3 | Genome sequencing and analysis of Aspergillus oryzae Masayuki Machida et al. · Nature | Dec 2005 | 1,272 |
| 4 | Complex Phenotype of Mice Lacking Occludin, a Component of Tight Junction Strands Mitinori Saitou, Mikio Furuse, Hiroyuki Sasaki et al. · Molecular Biology of the Cell | Dec 2000 | 1,199 |
| 5 | A Single Gene Product, Claudin-1 or -2, Reconstitutes Tight Junction Strands and Recruits Occludin in Fibroblasts Mikio Furuse, Hiroyuki Sasaki, Kazushi Fujimoto et al. · The Journal of Cell Biology | 19 Oct 1998 | 969 |
| 6 | Endothelial Claudin Kazumasa Morita, Hiroyuki Sasaki, Mikio Furuse et al. · The Journal of Cell Biology | 4 Oct 1999 | 870 |
| 7 | Integrated molecular analysis of adult T cell leukemia/lymphoma Keisuke Kataoka et al. · Nature Genetics | 5 Oct 2015 | 862 |
| 8 | ZO-1 and ZO-2 Independently Determine Where Claudins Are Polymerized in Tight-Junction Strand Formation Kazuaki Umeda, Junichi Ikenouchi, Sayaka Katahira-Tayama et al. · Cell | Aug 2006 | 837 |
| 9 | Manner of Interaction of Heterogeneous Claudin Species within and between Tight Junction Strands Mikio Furuse, Hiroyuki Sasaki, Shöichiro Tsukita · The Journal of Cell Biology | 15 Nov 1999 | 748 |
| 10 | Conversion of Zonulae Occludentes from Tight to Leaky Strand Type by Introducing Claudin-2 into Madin-Darby Canine Kidney I Cells Mikio Furuse, Kyoko Furuse, Hiroyuki Sasaki et al. · The Journal of Cell Biology | 9 Apr 2001 | 721 |
| 11 | Splicing factor SF3b as a target of the antitumor natural product pladienolide Yoshihiko Kotake, Koji Sagane, Takashi Owa et al. · Nature Chemical Biology | 22 Jul 2007 | 675 |
| 12 | CH5424802, a Selective ALK Inhibitor Capable of Blocking the Resistant Gatekeeper Mutant Hiroshi Sakamoto, Toshiyuki Tsukaguchi, Sayuri Hiroshima et al. · Cancer Cell | May 2011 | 636 |
| 13 | Clostridium perfringens Enterotoxin Fragment Removes Specific Claudins from Tight Junction Strands Noriyuki Sonoda, Mikio Furuse, Hiroyuki Sasaki et al. · The Journal of Cell Biology | 4 Oct 1999 | 616 |
| 14 | Claudin-11/OSP-based Tight Junctions of Myelin Sheaths in Brain and Sertoli Cells in Testis Kazumasa Morita, Hiroyuki Sasaki, Kazushi Fujimoto et al. · The Journal of Cell Biology | 3 May 1999 | 448 |
| 15 | Isolation of Human Induced Pluripotent Stem Cell-Derived Dopaminergic Progenitors by Cell Sorting for Successful Transplantation Daisuke Doi, Bumpei Samata, Mitsuko Katsukawa et al. · Stem Cell Reports | Mar 2014 | 445 |
| 16 | CLASP1 and CLASP2 bind to EB1 and regulate microtubule plus-end dynamics at the cell cortex Yuko Mimori‐Kiyosue, Ilya Grigoriev, Gideon W.A. Lansbergen et al. · The Journal of Cell Biology | 3 Jan 2005 | 433 |
| 17 | Chemokines in Immunity Osamu Yoshie, Toshio Imai, Hisayuki Nomiyama · Advances in immunology | 2001 | 429 |
| 18 | Junctional adhesion molecule (JAM) binds to PAR-3 Masahiko Itoh, Hiroyuki Sasaki, Mikio Furuse et al. · The Journal of Cell Biology | 6 Aug 2001 | 388 |
| 19 | Dual Functions of Fractalkine/CX3C Ligand 1 in Trafficking of Perforin+/Granzyme B+ Cytotoxic Effector Lymphocytes That Are Defined by CX3CR1 Expression Miyuki Nishimura, Hisanori Umehara, Takashi Nakayama et al. · The Journal of Immunology | Jun 2002 | 339 |
| 20 | Differences in neurogenic potential in floor plate cells along an anteroposterior location: midbrain dopaminergic neurons originate from mesencephalic floor plate cells Yuichi Ono, Tomoya Nakatani, Yoshimasa Sakamoto et al. · Development | 2 Aug 2007 | 337 |
| 21 | Fractalkine in Vascular Biology Hisanori Umehara, Eda T. Bloom, Toshiro Okazaki et al. · Arteriosclerosis Thrombosis and Vascular Biology | 16 Sep 2003 | 330 |
| 22 | The reconstituted ‘humanized liver’ in TK-NOG mice is mature and functional Masami Hasegawa, Kenji Kawai, T Mitsui et al. · Biochemical and Biophysical Research Communications | 20 Jan 2011 | 320 |
| 23 | CLASPs Attach Microtubule Plus Ends to the Cell Cortex through a Complex with LL5β Gideon W.A. Lansbergen, Ilya Grigoriev, Yuko Mimori‐Kiyosue et al. · Developmental Cell | Jul 2006 | 318 |
| 24 | Radixin deficiency causes conjugated hyperbilirubinemia with loss of Mrp2 from bile canalicular membranes Shojiro Kikuchi, Masaki Hata, Kanehisa Fukumoto et al. · Nature Genetics | 17 Jun 2002 | 311 |
| 25 | Cast Toshihisa Ohtsuka, Etsuko Takao‐Rikitsu, Eiji Inoue et al. · The Journal of Cell Biology | 5 Aug 2002 | 302 |
| 26 | Deficiency of Zonula Occludens-1 Causes Embryonic Lethal Phenotype Associated with Defected Yolk Sac Angiogenesis and Apoptosis of Embryonic Cells Tatsuya Katsuno, Kazuaki Umeda, Takeshi Matsui et al. · Molecular Biology of the Cell | 20 Mar 2008 | 301 |
| 27 | Claudin-2–deficient mice are defective in the leaky and cation-selective paracellular permeability properties of renal proximal tubules Shigeaki Muto, Masaki Hata, Junichi Taniguchi et al. · Proceedings of the National Academy of Sciences | 12 Apr 2010 | 301 |
| 28 | Mre11 is essential for the maintenance of chromosomal DNA in vertebrate cells Yuko Yamaguchi‐Iwai, Eiichiro Sonoda, Masao S. Sasaki et al. · The EMBO Journal | Dec 1999 | 284 |
| 29 | Centriolar Satellites Akiharu Kubo, Hiroyuki Sasaki, Akiko Yuba-Kubo et al. · The Journal of Cell Biology | 29 Nov 1999 | 273 |
| 30 | Establishment and Characterization of Cultured Epithelial Cells Lacking Expression of ZO-1 Kazuaki Umeda, Takeshi Matsui, Mayumi Nakayama et al. · Journal of Biological Chemistry | 30 Jul 2004 | 263 |
| 31 | Structure and Activity of Angiotensin I Converting Enzyme Inhibitory Peptides from Sake and Sake Lees Yoshiyuki Saito, Keiko Wanezaki, Akitsugu Kawato et al. · Bioscience Biotechnology and Biochemistry | 1994 | 242 |
| 32 | Implications of Nectin-like Molecule-2/IGSF4/RA175/SgIGSF/TSLC1/SynCAM1 in Cell-Cell Adhesion and Transmembrane Protein Localization in Epithelial Cells Tatsushi Shingai, Wataru Ikeda, Shigeki Kakunaga et al. · Journal of Biological Chemistry | Sep 2003 | 231 |
| 33 | Dynamic behavior of paired claudin strands within apposing plasma membranes Hiroyuki Sasaki, Chiyuki Matsui, Kyoko Furuse et al. · Proceedings of the National Academy of Sciences | 21 Mar 2003 | 226 |
| 34 | Physical and functional interaction of the active zone proteins, CAST, RIM1, and Bassoon, in neurotransmitter release Etsuko Takao‐Rikitsu, Sumiko Mochida, Eiji Inoue et al. · The Journal of Cell Biology | 19 Jan 2004 | 224 |
| 35 | Cell–matrix interface regulates dormancy in human colon cancer stem cells Yuki Ohta, Masayuki Fujii, Sirirat Takahashi et al. · Nature | 7 Jul 2022 | 214 |
| 36 | GPR31-dependent dendrite protrusion of intestinal CX3CR1+ cells by bacterial metabolites Naoki Morita, Eiji Umemoto, Setsuko Fujita et al. · Nature | 23 Jan 2019 | 211 |
| 37 | Ca2+-independent cell-adhesion activity of claudins, a family of integral membrane proteins localized at tight junctions Kôji Kubota, Mikio Furuse, Hiroyuki Sasaki et al. · Current Biology | Sep 1999 | 199 |
| 38 | GLP-1 release and vagal afferent activation mediate the beneficial metabolic and chronotherapeutic effects of D-allulose Yusaku Iwasaki, Sendo Mio, Katsuya Dezaki et al. · Nature Communications | 3 Jan 2018 | 198 |
| 39 | LIS1 and NDEL1 coordinate the plus‐end‐directed transport of cytoplasmic dynein Masami Yamada, Shiori Toba, Yuko Yoshida et al. · The EMBO Journal | 11 Sep 2008 | 196 |
| 40 | Single-cell gene profiling defines differential progenitor subclasses in mammalian neurogenesis Ayano Kawaguchi, Tomoko Ikawa, Takeya Kasukawa et al. · Development | 25 Aug 2008 | 195 |
| 41 | Endocytosis of E-cadherin regulated by Rac and Cdc42 small G proteins through IQGAP1 and actin filaments Genkichi Izumi, Toshiaki Sakisaka, Takeshi Baba et al. · The Journal of Cell Biology | 19 Jul 2004 | 187 |
| 42 | Studies on anticancer treatment with an oily anticancer drug injected into the ligated feeding hepatic artery for liver cancer Kenichiro Nakakuma, Seiki Tashiro, Takehisa Hiraoka et al. · Cancer | 15 Dec 1983 | 185 |
| 43 | Sustained inflammation after pericyte depletion induces irreversible blood-retina barrier breakdown Shuntaro Ogura et al. · JCI Insight | 8 Feb 2017 | 178 |
| 44 | Direct Binding of Cell Polarity Protein PAR-3 to Cell-Cell Adhesion Molecule Nectin at Neuroepithelial Cells of Developing Mouse Kyoji Takekuni, Wataru Ikeda, Tsutomu Fujito et al. · Journal of Biological Chemistry | Feb 2003 | 178 |
| 45 | Compartmentalization established by claudin-11-based tight junctions in stria vascularis is required for hearing through generation of endocochlear potential Shin‐ichiro Kitajiri, Tatsuo Miyamoto, Akihito Mineharu et al. · Journal of Cell Science | 29 Sep 2004 | 172 |
| 46 | Carbohydrate Binding Specificity of a Fucose-specific Lectin from Aspergillus oryzae Kengo Matsumura, Katsuya Higashida, Hiroki Ishida et al. · Journal of Biological Chemistry | 23 Mar 2007 | 171 |
| 47 | Tight junctions in Schwann cells of peripheral myelinated axons Tatsuo Miyamoto, Kazumasa Morita, Daisuke Takemoto et al. · The Journal of Cell Biology | 9 May 2005 | 167 |
| 48 | Involvement of LMO7 in the Association of Two Cell-Cell Adhesion Molecules, Nectin and E-cadherin, through Afadin and α-Actinin in Epithelial Cells Takako Ooshio, Kenji Irie, Koji Morimoto et al. · Journal of Biological Chemistry | Jul 2004 | 166 |
| 49 | Ontogeny-recapitulating generation and tissue integration of ES cell–derived Purkinje cells Keiko Muguruma, Ayaka Nishiyama, Yūichi Ono et al. · Nature Neuroscience | 12 Sep 2010 | 162 |
| 50 | Migration of CX3CR1‐positive T cells producing type 1 cytokines and cytotoxic molecules into the synovium of patients with rheumatoid arthritis Toshihiro Nanki, Toshio Imai, Kenji Nagasaka et al. · Arthritis & Rheumatism | Nov 2002 | 159 |
Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.