| 1 |
Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS): An update (2014–2018)
Jean‐Pascal Lefaucheur et al. · Clinical Neurophysiology
Open access |
31 Dec 2019 |
2,413 |
| 2 |
Durvalumab plus platinum–etoposide versus platinum–etoposide in first-line treatment of extensive-stage small-cell lung cancer (CASPIAN): a randomised, controlled, open-label, phase 3 trial
Luis G Paz-Ares et al. · The Lancet
246 authors |
4 Oct 2019 |
2,310 |
| 3 |
Update on treatments for nonmotor symptoms of Parkinson's disease—an evidence‐based medicine review
Klaus Seppi, К. Ray Chaudhuri, Miguel M Coelho et al. · Movement Disorders
Open access |
17 Jan 2019 |
1,011 |
| 4 |
Persistent immune activation in HIV-1 infection is associated with progression to AIDS
Mette D. Hazenberg, Sigrid A. Otto, Birgit HB van Benthem et al. · AIDS
|
27 Aug 2003 |
786 |
| 5 |
Durvalumab, with or without tremelimumab, plus platinum–etoposide versus platinum–etoposide alone in first-line treatment of extensive-stage small-cell lung cancer (CASPIAN): updated results from a randomised, controlled, open-label, phase 3 trial
Jonathan Wade Goldman et al. · The Lancet Oncology
Open access253 authors |
4 Dec 2020 |
707 |
| 6 |
Once-weekly tirzepatide versus once-daily insulin degludec as add-on to metformin with or without SGLT2 inhibitors in patients with type 2 diabetes (SURPASS-3): a randomised, open-label, parallel-group, phase 3 trial
Bernhard H. Ludvik, Francesco Giorgino, Esteban Jódar et al. · The Lancet
|
Aug 2021 |
628 |
| 7 |
The O nset of N onmotor S ymptoms in P arkinson's disease ( T he ONSET PD S tudy)
Claustre Pont‐Sunyer et al. · Movement Disorders
|
Dec 2014 |
512 |
| 8 |
Risk Assessment of Recurrence in Patients With Unprovoked Deep Vein Thrombosis or Pulmonary Embolism
Sabine Eichinger, Georg Heinze, Lisanne M. Jandeck et al. · Circulation
|
30 Mar 2010 |
508 |
| 9 |
Epidemiology, diagnosis, preoperative evaluation and prognostic assessment of upper-tract urothelial carcinoma (UTUC)
Francesco Soria, Shahrokh François Shariat, Seth P. Lerner et al. · World Journal of Urology
Open access |
7 Sep 2016 |
485 |
| 10 |
A European Evidence-Based Guideline for the Prevention of Type 2 Diabetes
Bernhard Paulweber et al. · Hormone and Metabolic Research
Open access129 authors |
Apr 2010 |
481 |
| 11 |
Cardiopulmonary recovery after COVID-19: an observational prospective multicentre trial
Thomas Sonnweber et al. · European Respiratory Journal
Open access |
10 Dec 2020 |
452 |
| 12 |
European Organisation for Research and Treatment of Cancer consensus recommendations for the treatment of mycosis fungoides/Sézary syndrome – Update 2017
Franz Trautinger, Johanna Eder, Chalid Assaf et al. · European Journal of Cancer
Open access |
31 Mar 2017 |
452 |
| 13 |
Complement activating antibodies to myelin oligodendrocyte glycoprotein in neuromyelitis optica and related disorders
Simone Mader, Viktoria Gredler, Kathrin Schanda et al. · Journal of Neuroinflammation
Open access |
Dec 2011 |
451 |
| 14 |
Mechanisms of Disease: hepatic steatosis in type 2 diabetes—pathogenesis and clinical relevance
Michael Roden · Nature Clinical Practice Endocrinology & Metabolism
|
Jun 2006 |
409 |
| 15 |
Levodopa Dose Equivalency in Parkinson's Disease: Updated Systematic Review and Proposals
Stefanie Theresa Jost et al. · Movement Disorders
ReviewOpen access |
5 May 2023 |
390 |
| 16 |
Durvalumab, with or without tremelimumab, plus platinum-etoposide in first-line treatment of extensive-stage small-cell lung cancer: 3-year overall survival update from CASPIAN
Luis G Paz-Ares et al. · ESMO Open
Open access |
10 Mar 2022 |
349 |
| 17 |
Effectiveness of Progressive Muscle Relaxation, Deep Breathing, and Guided Imagery in Promoting Psychological and Physiological States of Relaxation
Loren L. Toussaint, Quang Anh Nguyen, Claire Roettger et al. · Evidence-based Complementary and Alternative Medicine
Open access |
2 Jul 2021 |
325 |
| 18 |
European Society of Anaesthesiology and European Board of Anaesthesiology guidelines for procedural sedation and analgesia in adults
Jochen Hinkelbein, Massimo Lamperti, Jonas Åkeson et al. · European Journal of Anaesthesiology
Open access |
6 Sep 2017 |
317 |
| 19 |
Transcutaneous Vagus Nerve Stimulation (tVNS) for Treatment of Drug-Resistant Epilepsy: A Randomized, Double-Blind Clinical Trial (cMPsE02)
Sebastian Bauer, Hartmut Baier, Christian Baumgärtner et al. · Brain stimulation
Open access |
21 Jan 2016 |
281 |
| 20 |
Macrophages eliminate circulating tumor cells after monoclonal antibody therapy
Nuray Gül, Liane Babes, Kerstin Siegmund et al. · Journal of Clinical Investigation
Open access |
15 Jan 2014 |
276 |
| 21 |
Risk assessment for recurrent venous thrombosis
Paul Alexander Kyrle, Frits Richard Rosendaal, Sabine Eichinger · The Lancet
|
Dec 2010 |
264 |
| 22 |
2021 EULAR recommendations regarding lifestyle behaviours and work participation to prevent progression of rheumatic and musculoskeletal diseases
James M. Gwinnutt, Maud Wieczorek, Andra Rodica Balanescu et al. · Annals of the Rheumatic Diseases
Open access |
8 Mar 2022 |
262 |
| 23 |
An immunoepidemiological approach to asthma: identification of in-vitro T cell response patterns associated with different wheezing phenotypes in children
Tricia Heaton, Julie Rowe, Steve Turner et al. · The Lancet
Open access |
2005 |
257 |
| 24 |
Muscle Mitochondrial ATP Synthesis and Glucose Transport/Phosphorylation in Type 2 Diabetes
Julia Szendroedi, Albrecht Ingo Schmid, Marek Chmelík et al. · PLoS Medicine
Open access |
26 Apr 2007 |
247 |
| 25 |
Take Action to Prevent Diabetes – The IMAGE Toolkit for the Prevention of Type 2 Diabetes in Europe
Jaana Lindström et al. · Hormone and Metabolic Research
Open access108 authors |
Apr 2010 |
239 |
| 26 |
Liver ATP Synthesis Is Lower and Relates to Insulin Sensitivity in Patients With Type 2 Diabetes
Albrecht Ingo Schmid, Julia Szendroedi, Marek Chmelík et al. · Diabetes Care
Open access |
8 Jan 2011 |
217 |
| 27 |
MACVIA-ARIA Sentinel NetworK for allergic rhinitis (MASK-rhinitis): the new generation guideline implementation
Jean Bousquet et al. · Allergy
Open access263 authors |
4 Jul 2015 |
205 |
| 28 |
Molecular profiling of cytomegalovirus-induced human CD8+ T cell differentiation
Kirsten M. L. Hertoghs, Perry D. Moerland, Amber van Stijn et al. · Journal of Clinical Investigation
Open access |
Oct 2010 |
201 |
| 29 |
The Impact of Vitamin D, Calcium, Protein Supplementation, and Physical Exercise on Bone Metabolism After Bariatric Surgery: The BABS Study
Christian Muschitz, Roland Kocijan, Judith Haschka et al. · Journal of Bone and Mineral Research
|
9 Sep 2015 |
199 |
| 30 |
Therapeutic PD-L1 antibodies are more effective than PD-1 antibodies in blocking PD-1/PD-L1 signaling
Annika De Sousa Linhares, Claire Battin, Sabrina Jutz et al. · Scientific Reports
Open access |
7 Aug 2019 |
198 |
| 31 |
Beneficial effects of multi-disciplinary rehabilitation in postacute COVID-19: an observational cohort study
Bernhard Puchner, Sabina Sahanic, Rudolf Kirchmair et al. · European Journal of Physical and Rehabilitation Medicine
|
May 2021 |
186 |
| 32 |
Persisting alterations of iron homeostasis in COVID-19 are associated with non-resolving lung pathologies and poor patients’ performance: a prospective observational cohort study
Thomas Sonnweber et al. · Respiratory Research
Open access |
21 Oct 2020 |
185 |
| 33 |
To test or not to test? Laboratory support for the diagnosis of Lyme borreliosis: a position paper of ESGBOR, the ESCMID study group for Lyme borreliosis
Ram Benny Dessau, Alje Pieter van Dam, Volker Fingerle et al. · Clinical Microbiology and Infection
Open access |
5 Sep 2017 |
180 |
| 34 |
Intravenous fosfomycin—back to the future. Systematic review and meta-analysis of the clinical literature
Béatrice Grabein, Winfried B. Graninger, Jesús Rodríguez‐Baño et al. · Clinical Microbiology and Infection
ReviewOpen access |
9 Dec 2016 |
177 |
| 35 |
Risk of Rupture of Small Anterior Communicating Artery Aneurysms Is Similar to Posterior Circulation Aneurysms
Philippe Bijlenga et al. · Stroke
Open access111 authors |
31 Jul 2013 |
165 |
| 36 |
Semaglutide and walking capacity in people with symptomatic peripheral artery disease and type 2 diabetes (STRIDE): a phase 3b, double-blind, randomised, placebo-controlled trial
Marc P. Bonaca, Andrei‐Mircea Catarig, Kim Christian Houlind et al. · The Lancet
|
31 Mar 2025 |
157 |
| 37 |
The Role of Surgery in Metastatic Bladder Cancer: A Systematic Review
Mohammad M. Abufaraj, Guido M. Dalbagni, Siamak Daneshmand et al. · European Urology
ReviewOpen access |
7 Nov 2017 |
150 |
| 38 |
Extent and Clinical Consequences of Antibody Formation Against Adalimumab in Patients With Plaque Psoriasis
Lidian L. A. Lecluse, R.J.B. Driessen, Phyllis Ira Spuls et al. · Archives of Dermatology
Open access |
Feb 2010 |
150 |
| 39 |
Premature senescence of endothelial cells upon chronic exposure to TNFα can be prevented by N-acetyl cysteine and plumericin
Shafaat Yar Khan, Ezzat Mohamed Awad, André Oszwald et al. · Scientific Reports
Open access |
3 Jan 2017 |
147 |
| 40 |
Occupational risk factors for osteoarthritis of the knee: a meta-analysis
Daniel F. McWilliams, Burkhard F. Leeb, Stella G. Muthuri et al. · Osteoarthritis and Cartilage
ReviewOpen access |
7 Mar 2011 |
147 |
| 41 |
An up-to-date catalog of available urinary biomarkers for the surveillance of non-muscle invasive bladder cancer
Francesco Soria, Michael J. Droller, Yair Lotan et al. · World Journal of Urology
Open access |
21 Jun 2018 |
143 |
| 42 |
Anti‐contactin‐associated protein‐2 encephalitis: relevance of antibody titres, presentation and outcome
Christian G. Bien, Zulfiya Mirzadjanova, Christoph Baumgartner et al. · European Journal of Neurology
|
27 Oct 2016 |
143 |
| 43 |
First-line Immunotherapy-based Combinations for Metastatic Renal Cell Carcinoma: A Systematic Review and Network Meta-analysis
Fahad Quhal, Keiichiro Mori, Andreas Bruchbacher et al. · European Urology Oncology
Review |
20 Mar 2021 |
142 |
| 44 |
Seizure detection using scalp‐ EEG
Christoph Baumgartner, Johannes Peter Koren · Epilepsia
|
Jun 2018 |
139 |
| 45 |
Protection against Renal Ischemia Reperfusion Injury by CD44 Disruption
Kasper M. A. Rouschop, Joris J. T. H. Roelofs, Nike Claessen et al. · Journal of the American Society of Nephrology
|
18 May 2005 |
139 |
| 46 |
Diagnostic performance of multidetector computed tomographic (MDCTU) in upper tract urothelial carcinoma (UTUC): a systematic review and meta-analysis
Florian Janisch, Shahrokh François Shariat, Pascal Baltzer et al. · World Journal of Urology
Review |
18 Jul 2019 |
138 |
| 47 |
Assessment of 31P relaxation times in the human calf muscle: A comparison between 3 T and 7 T in vivo
Wolfgang Bogner, Marek Chmelík, Albrecht Ingo Schmid et al. · Magnetic Resonance in Medicine
Open access |
12 Jun 2009 |
137 |
| 48 |
Towards a tailored diagnostic standard for future diagnostic studies in pulmonary embolism: communication from the SSC of the ISTH
Charlotte E. A. Dronkers, Tom van der Hulle, Grégoire Le Gal et al. · Journal of Thrombosis and Haemostasis
Open access |
15 Feb 2017 |
127 |
| 49 |
Advanced cutaneous squamous cell carcinoma: A retrospective analysis of patient profiles and treatment patterns—Results of a non-interventional study of the DeCOG
Uwe Hillen et al. · European Journal of Cancer
|
14 Apr 2018 |
125 |
| 50 |
Accuracy of machine learning classifiers using bilateral data from a Scheimpflug camera for identifying eyes with preclinical signs of keratoconus
Illés Kovács, Kata Miháltz, Kinga Kránitz et al. · Journal of Cataract & Refractive Surgery
|
Feb 2016 |
124 |