| 1 |
DNA methylation-based classification of central nervous system tumours
David Capper et al. · Nature
Open access143 authors |
13 Mar 2018 |
3,228 |
| 2 |
Enfortumab Vedotin and Pembrolizumab in Untreated Advanced Urothelial Cancer
Thomas B. Powles et al. · New England Journal of Medicine
Open access |
6 Mar 2024 |
1,072 |
| 3 |
The German hospital malnutrition study
Matthias Pirlich, Tatjana Schütz, Kristina Norman et al. · Clinical Nutrition
|
19 May 2006 |
721 |
| 4 |
Fabry disease revisited: Management and treatment recommendations for adult patients
Alberto Arduan Ortiz, Dominique Paul Germain, Robert J. Desnick et al. · Molecular Genetics and Metabolism
Open access |
28 Feb 2018 |
661 |
| 5 |
Processing of Generator-Produced 68Ga for Medical Application
Konstantin Zhernosekov, D. V. Filosofov, Richard Paul Baum et al. · Journal of Nuclear Medicine
Open access |
15 Sep 2007 |
507 |
| 6 |
Acute Cholecystitis
Carsten N. Gutt et al. · Annals of Surgery
|
9 Aug 2013 |
460 |
| 7 |
Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma
Linda M. Liau et al. · JAMA Oncology
Open access |
17 Nov 2022 |
451 |
| 8 |
Understanding the barriers to setting up a healthcare quality improvement process in resource-limited settings: a situational analysis at the Medical Department of Kamuzu Central Hospital in Lilongwe, Malawi
Josephine Nana Afrakoma Agyeman-Duah, Antje Theurer, Charles K. Munthali et al. · BMC Health Services Research
Open access |
2 Jan 2014 |
354 |
| 9 |
Recommendations for initiation and cessation of enzyme replacement therapy in patients with Fabry disease: the European Fabry Working Group consensus document
Marieke Biegstraaten et al. · Orphanet Journal of Rare Diseases
Open access |
27 Mar 2015 |
352 |
| 10 |
Chemical changes of human knee joint menisci in various stages of degeneration.
Johanna Herwig, E. Egner, Eckhart Buddecke · Annals of the Rheumatic Diseases
Open access |
Aug 1984 |
300 |
| 11 |
Anaplastic astrocytoma with piloid features, a novel molecular class of IDH wildtype glioma with recurrent MAPK pathway, CDKN2A/B and ATRX alterations
Annekathrin Reinhardt et al. · Acta Neuropathologica
Open access |
21 Mar 2018 |
291 |
| 12 |
HLA Antibody Specification Using Single-Antigen Beads—A Technical Solution for the Prozone Effect
M. Schnaidt, Christof Weinstock, Marija Jurisic et al. · Transplantation
|
14 Jul 2011 |
242 |
| 13 |
Suicidal death of erythrocytes in recurrent hemolytic uremic syndrome
Philipp Alexander Lang, Ortraud Beringer, Jan Peter Nicolay et al. · Journal of Molecular Medicine
|
18 Apr 2006 |
239 |
| 14 |
Central Nervous System Tuberculosis
Martin Schaller, Felix Sebastian Wicke, Christian Foerch et al. · Clinical Neuroradiology
|
17 Sep 2018 |
226 |
| 15 |
Reference Values for the Trace Elements Copper, Manganese, Selenium, and Zinc in the Serum / Plasma of Children, Adolescents, and Adults
Margarete Rükgauer, J. Klein, Jürgen D. Kruse-Jarres · Journal of Trace Elements in Medicine and Biology
|
1997 |
225 |
| 16 |
Operative treatment of 733 patients with acute thoracolumbar spinal injuries: comprehensive results from the second, prospective, internet-based multicenter study of the Spine Study Group of the German Association of Trauma Surgery
Maximilian Reinhold, C. Knop, Rudolf W. Beisse et al. · European Spine Journal
Open access |
24 May 2010 |
224 |
| 17 |
European expert consensus statement on therapeutic goals in Fabry disease
Christoph Wanner et al. · Molecular Genetics and Metabolism
Open access |
12 Jun 2018 |
218 |
| 18 |
Interim Results of a Multicenter Trial with the New Electronic Subretinal Implant Alpha AMS in 15 Patients Blind from Inherited Retinal Degenerations
Katarína Štingl, Ruth Schippert, Karl Ulrich Bartz‐Schmidt et al. · Frontiers in Neuroscience
Open access |
23 Aug 2017 |
208 |
| 19 |
Long-term intubation and high rate of tracheostomy in COVID-19 patients might determine an unprecedented increase of airway stenoses: a call to action from the European Laryngological Society
Cesare Piazza, Marta Filauro, Frederik G. Dikkers et al. · European Archives of Oto-Rhino-Laryngology
Open access |
6 Jun 2020 |
207 |
| 20 |
Clinical Predictors for Germline Mutations in Head and Neck Paraganglioma Patients: Cost Reduction Strategy in Genetic Diagnostic Process as Fall-Out
Hartmut P.H. Neumann et al. · Cancer Research
Open access |
7 Apr 2009 |
196 |
| 21 |
Elective Nephron Sparing Surgery Should Become Standard Treatment for Small Unilateral Renal Cell Carcinoma: Long-term Survival Data of 216 Patients
Frauke Becker, Stefan Siemer, U. Humke et al. · European Urology
|
10 Dec 2005 |
195 |
| 22 |
Basic surgical principles with ITI implants Note
Daniel Buser, Thomas von Arx, Christiaan ten Bruggenkate et al. · Clinical Oral Implants Research
|
Sep 2000 |
192 |
| 23 |
Effectiveness of triclosan-coated PDS Plus versus uncoated PDS II sutures for prevention of surgical site infection after abdominal wall closure: the randomised controlled PROUD trial
Markus K. Diener et al. · The Lancet
Open access |
7 Apr 2014 |
191 |
| 24 |
Acquired resistance to imatinib in gastrointestinal stromal tumours caused by multiple KIT mutations
Eva Wardelmann, Nadja Thomas, Sabine Merkelbach‐Bruse et al. · The Lancet Oncology
|
Apr 2005 |
191 |
| 25 |
Developing the skill of endotracheal intubation: implication for emergency medicine
Michael Bernhard, Stefan Mohr, Markus A. Weigand et al. · Acta Anaesthesiologica Scandinavica
|
14 Oct 2011 |
190 |
| 26 |
Excellent Long-Term Cancer Control with Elective Nephron-Sparing Surgery for Selected Renal Cell Carcinomas Measuring More Than 4cm
Frank O. Becker, Stefan Siemer, Markus Hack et al. · European Urology
|
24 Mar 2006 |
186 |
| 27 |
Evolution of the mid range theory of comfort for outcomes research
Katharine Y. Kolcaba · Nursing Outlook
|
Mar 2001 |
185 |
| 28 |
Omission of dacarbazine or bleomycin, or both, from the ABVD regimen in treatment of early-stage favourable Hodgkin's lymphoma (GHSG HD13): an open-label, randomised, non-inferiority trial
Karolin Behringer et al. · The Lancet
|
21 Dec 2014 |
184 |
| 29 |
German Cancer Society Neuro‐Oncology Working Group NOA‐03 multicenter trial of single‐agent high‐dose methotrexate for primary central nervous system lymphoma
Ulrich Herrlinger, Martin Schabet, Wolfram Brugger et al. · Annals of Neurology
|
31 Jan 2002 |
182 |
| 30 |
S2k-Leitlinie Neuroendokrine Tumore
Authors, Collaborators:, Deutsche Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankhe et al. · Zeitschrift für Gastroenterologie
Open access |
Jun 2018 |
181 |
| 31 |
Biological tumor volume in 18 FET-PET before radiochemotherapy correlates with survival in GBM
Bogdana Suchorska et al. · Neurology
Open access |
22 Jan 2015 |
177 |
| 32 |
The Keyhole Concept in Neurosurgery
Róbert Reisch, Axel Thomas Stadie, Ralf Alfons Kockro et al. · World Neurosurgery
|
10 Feb 2012 |
173 |
| 33 |
Elastic Stable Intramedullary Nailing of Midclavicular Fractures With a Titanium Nail
Axel Jubel, Jonas Andermahr, Gereon Schiffer et al. · Clinical Orthopaedics and Related Research
|
Mar 2003 |
171 |
| 34 |
First Workshop for Detection of Heparin-induced Antibodies: Validation of the Heparin-induced Platelet-activation Test (HIPA) in Comparison with a PF4/Heparin ELISA
Petra Eichler, Uwe Budde, Sylvia K. Haas et al. · Thrombosis and Haemostasis
|
1999 |
165 |
| 35 |
The Keyhole Concept in Aneurysm Surgery: Results of the Past 20 Years
Gerrit Fischer, Axel Thomas Stadie, Róbert Reisch et al. · Operative Neurosurgery
|
4 Jan 2011 |
155 |
| 36 |
Evaluation of clinical dry weight assessment in haemodialysis patients using bioimpedance spectroscopy: a cross-sectional study
Jens Passauer, Hristo Petrov, Andreas Schleser et al. · Nephrology Dialysis Transplantation
|
6 Oct 2009 |
148 |
| 37 |
Efficacy and safety of tacrolimus compared with cyclosporin A microemulsion in renal transplantation: 2 year follow-up results
Bernhard Karl Krämer, Giuseppe Montagnino, Domingo del Castillo et al. · Nephrology Dialysis Transplantation
Open access |
Mar 2005 |
142 |
| 38 |
Cytokeratin 8/18 expression indicates a poor prognosis in squamous cell carcinomas of the oral cavity
Thomas Fillies, R. Werkmeister, Jens Packeisen et al. · BMC Cancer
Open access |
13 Jan 2006 |
142 |
| 39 |
Phase II study of paclitaxel in patients with relapsed or cisplatin-refractory testicular cancer
Carsten Bokemeyer, J. Beyer, Bernd Metzner et al. · Annals of Oncology
Open access |
1996 |
141 |
| 40 |
Efficacy and safety of trimodulin, a novel polyclonal antibody preparation, in patients with severe community-acquired pneumonia: a randomized, placebo-controlled, double-blind, multicenter, phase II trial (CIGMA study)
Tobias Welte et al. · Intensive Care Medicine
Open access |
Apr 2018 |
138 |
| 41 |
LBA6 EV-302/KEYNOTE-A39: Open-label, randomized phase III study of enfortumab vedotin in combination with pembrolizumab (EV+P) vs chemotherapy (Chemo) in previously untreated locally advanced metastatic urothelial carcinoma (la/mUC)
Thomas B. Powles, Begona Pérez Valderrama, Shilpa Gupta et al. · Annals of Oncology
Open access |
Oct 2023 |
137 |
| 42 |
HOPE Fixation: A Novel Fixing Method and Paraffin-embedding Technique for Human Soft Tissues
Jürgen Olert, Klaus-Hermann Wiedorn, Torsten Goldmann et al. · Pathology - Research and Practice
|
2001 |
137 |
| 43 |
Whole body positron emission tomography in the treatment of Hodgkin disease
Beatrix Hueltenschmidt, Marie‐Luise Sautter‐Bihl, Oliver Lang et al. · Cancer
|
2001 |
137 |
| 44 |
Nicht-invasive Beatmung als Therapie der akuten respiratorischen Insuffizienz
Michael Westhoff et al. · Pneumologie
Open access |
9 Dec 2015 |
132 |
| 45 |
ADRENAL METASTASES IN 1,635 PATIENTS WITH RENAL CELL CARCINOMA: OUTCOME AND INDICATION FOR ADRENALECTOMY
Stephan Siemer, Jens Lehmann, Jörn Kamradt et al. · The Journal of Urology
|
3 May 2004 |
132 |
| 46 |
Extracorporeal shockwave lithotripsy (ESWL) and endourology: an ideal combination for the treatment of kidney stones
FERDINAND EISENBERGER, Gerhard J. Fuchs, Katherine Ann Reimão Miller et al. · World Journal of Urology
|
Mar 1985 |
132 |
| 47 |
Primary vitrectomy without scleral buckling for rhegmatogenous retinal detachment
Heinrich Heimann, Norbert Bornfeld, Wilko Friedrichs et al. · Graefe s Archive for Clinical and Experimental Ophthalmology
|
Sep 1996 |
128 |
| 48 |
Large-dose Hydroxyethyl Starch 130/0.4 Does Not Increase Blood Loss and Transfusion Requirements in Coronary Artery Bypass Surgery Compared with Hydroxyethyl Starch 200/0.5 at Recommended Doses
Stefan‐Mario Kasper, P Meinert, Sandra Kampe et al. · Anesthesiology
Open access |
Jul 2003 |
127 |
| 49 |
Locked Posterior Dislocation of the Shoulder: Treatment Using Rotational Osteotomy of the Humerus
P. Keppler, U. Holz, F. W. Thielemann et al. · Journal of Orthopaedic Trauma
|
Aug 1994 |
127 |
| 50 |
Typical Patterns of Bone Involvement in Whole-Body MRI of Patients with Chronic Recurrent Multifocal Osteomyelitis (CRMO)
Thekla v. Kalle, Nils Heim, Toni Hospach et al. · RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren
Open access |
21 May 2013 |
125 |