Institution · Kissei Pharmaceutical (Japan)

Most cited papers from Kissei Pharmaceutical (Japan)

Kissei Pharmaceutical (Japan)

What are the most cited papers from Kissei Pharmaceutical (Japan)?

The most cited paper from Kissei Pharmaceutical (Japan) is "Execution of Apoptosis Signal-regulating Kinase 1 (ASK1)-induced Apoptosis by the Mitochondria-dependent Caspase Activation" (Takiko Hatai, Atsushi Matsuzawa, Seiji Inoshita et al., 2000), with 334 citations. Next come "Advanced Glycation End Products-driven Angiogenesis in Vitro" (276) and "Intramolecular Nonbonded S···O Interaction Recognized in (Acylimino)thiadiazoline Derivatives as Angiotensin II Receptor Antagonists and Related Compounds" (271).

Published TypeFieldAccessCitations

Showing 50 of 59 papers. Every paper with more than 76 citations is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	Execution of Apoptosis Signal-regulating Kinase 1 (ASK1)-induced Apoptosis by the Mitochondria-dependent Caspase Activation Takiko Hatai, Atsushi Matsuzawa, Seiji Inoshita et al. · Journal of Biological Chemistry Open access	Aug 2000	334
2	Advanced Glycation End Products-driven Angiogenesis in Vitro Sho‐ichi Yamagishi, Hideto Yonekura, Yasuhiko Yamamoto et al. · Journal of Biological Chemistry Open access	Mar 1997	276
3	Intramolecular Nonbonded S···O Interaction Recognized in (Acylimino)thiadiazoline Derivatives as Angiotensin II Receptor Antagonists and Related Compounds Yoshimitsu Nagao, Terukage Hirata, Satoru Goto et al. · Journal of the American Chemical Society	20 Mar 1998	271
4	Sergliflozin, a Novel Selective Inhibitor of Low-Affinity Sodium Glucose Cotransporter (SGLT2), Validates the Critical Role of SGLT2 in Renal Glucose Reabsorption and Modulates Plasma Glucose Level Kenji Katsuno, Yoshikazu Fujimori, Yukiko Takemura et al. · Journal of Pharmacology and Experimental Therapeutics	18 Oct 2006	267
5	Physiological Roles of ASK1-Mediated Signal Transduction in Oxidative Stress- and Endoplasmic Reticulum Stress-Induced Apoptosis: Advanced Findings from ASK1 Knockout Mice Atsushi Matsuzawa, Hideki Nishitoh, Kei Tobiume et al. · Antioxidants and Redox Signaling	Jun 2002	252
6	Costimulation through B7-2 (CD86) Is Required for the Induction of a Lung Mucosal T Helper Cell 2 (TH2) Immune Response and Altered Airway Responsiveness Shogo Tsuyuki, Junko Tsuyuki, Karin Einsle et al. · The Journal of Experimental Medicine Open access	5 May 1997	251
7	Effects of bezafibrate, PPAR pan-agonist, and GW501516, PPARδ agonist, on development of steatohepatitis in mice fed a methionine- and choline-deficient diet Tatsuya Nagasawa, Yoichi Inada, Shigeru Nakano et al. · European Journal of Pharmacology	Mar 2006	235
8	Functional and molecular biological evidence for a possible β3‐adrenoceptor in the human detrusor muscle Yasuhiko Igawa, Yoshinobu Yamazaki, Hiroo Takeda et al. · British Journal of Pharmacology Open access	Feb 1999	229
9	Regulation of Interleukin-1β-induced Interleukin-6 Gene Expression in Human Fibroblast-like Synoviocytes by p38 Mitogen-activated Protein Kinase Keiji Miyazawa, Akio Mori, Hiroshi Miyata et al. · Journal of Biological Chemistry Open access	Sep 1998	225
10	Remogliflozin Etabonate, in a Novel Category of Selective Low-Affinity Sodium Glucose Cotransporter (SGLT2) Inhibitors, Exhibits Antidiabetic Efficacy in Rodent Models Yoshikazu Fujimori, Kenji Katsuno, Ikumi Nakashima et al. · Journal of Pharmacology and Experimental Therapeutics	26 Jun 2008	221
11	Mouse Model of Airway Remodeling Kazuhiko Shinagawa, Masami Kojima · American Journal of Respiratory and Critical Care Medicine	14 Jul 2003	213
12	PHARMACOLOGICAL PROPERTIES OF N‐(3′,4′‐DIMETHOXYCINNAMOYL) ANTHRANILIC ACID (N‐5′), A NEW ANTI‐ATOPIC AGENT Hiroshi Azuma, Kazuhide Banno, Toshihiro Yoshimura · British Journal of Pharmacology Open access	Dec 1976	209
13	SLC5A9/SGLT4, a new Na+-dependent glucose transporter, is an essential transporter for mannose, 1,5-anhydro-D-glucitol, and fructose Shigeki Tazawa, Tokuhisa Yamato, Hideki Fujikura et al. · Life Sciences	12 Nov 2004	208
14	Efficacy and safety of ustekinumab in Japanese patients with moderate‐to‐severe plaque‐type psoriasis: Long‐term results from a phase 2/3 clinical trial Atsuyuki Igarashi, Takeshi Kato, Mai Kato et al. · The Journal of Dermatology Open access	29 Sep 2011	206
15	The Mechanism Involved in the Inhibitory Action of Tranilast on Collagen Biosynthesis of Keloid Fibroblasts. Haruo SUZAWA, Shinji Kikuchi, Nobuhiko Arai et al. · The Japanese Journal of Pharmacology Open access	1992	200
16	Molecular Mechanisms of the Decision between Life and Death: Regulation of Apoptosis by Apoptosis Signal-Regulating Kinase 1 Atsushi Matsuzawa, Hidenori Ichijo · The Journal of Biochemistry	Jul 2001	173
17	Sphingosine 1‐phosphate/sphingosine 1‐phosphate receptor 1 signaling in rheumatoid synovium: Regulation of synovial proliferation and inflammatory gene expression Masayasu Kitano, Timothy Hla, Masahiro Sekiguchi et al. · Arthritis & Rheumatism	28 Feb 2006	166
18	Physicochemical and Functional Properties of Buckwheat Protein Product Hiroyuki Tomotake, Iwao Shimaoka, Jun Kayashita et al. · Journal of Agricultural and Food Chemistry	28 Feb 2002	165
19	Consumption of Buckwheat Protein Lowers Plasma Cholesterol and Raises Fecal Neutral Sterols in Cholesterol-Fed Rats Because of Its Low Digestibility Jun Kayashita, Iwao Shimaoka, Misao Nakajoh et al. · Journal of Nutrition Open access	Jul 1997	149
20	anti-Selective Catalytic Asymmetric Nitroaldol Reaction via a Heterobimetallic Heterogeneous Catalyst Tatsuya Nitabaru, Akihiro Nojiri, Makoto Kobayashi et al. · Journal of the American Chemical Society	9 Sep 2009	147
21	A Buckwheat Protein Product Suppresses Gallstone Formation and Plasma Cholesterol More Strongly than Soy Protein Isolate in Hamsters Iwao Shimaoka, Hiroyuki Tomotake, Jun Kayashita et al. · Journal of Nutrition Open access	Jul 2000	146
22	ASK1 and ASK2 differentially regulate the counteracting roles of apoptosis and inflammation in tumorigenesis Takayuki Iriyama et al. · The EMBO Journal Open access	12 Feb 2009	129
23	Inhibitory Action of Tranilast, an Anti-Allergic Drug, on the Release of Cytokines and PGE2 from Human Monocytes-Macrophages. Haruo SUZAWA, Shinji Kikuchi, Kiyoshi Ichikawa et al. · The Japanese Journal of Pharmacology Open access	1992	128
24	Establishment and Characterization of a Novel Human Rheumatoid Fibroblast-Like Synoviocyte Line, MH7A, Immortalized with SV40 T Antigen Keiji Miyazawa, Akio Mori, Hirokazu Okudaira · The Journal of Biochemistry	Dec 1998	126
25	Reduced phototoxicity of a fluoroquinolone antibacterial agent with a methoxy group at the 8 position in mice irradiated with long-wavelength UV light Kiyoshi Marutani, Marissa L. Matsumoto, Yoshiki Katsumi Osamu Otabe et al. · Antimicrobial Agents and Chemotherapy Open access	Oct 1993	119
26	Evaluation of the rodent micronucleus assay by a 28‐day treatment protocol: Summary of the 13th Collaborative Study by the Collaborative Study Group for the Micronucleus Test (CSGMT)/Environmental Mutagen Society of Japan (JEMS)–Mammalian Mutagenicity Study Group (MMS) Shuichi Hamada et al. · Environmental and Molecular Mutagenesis	2001	118
27	Nonoverweight nonalcoholic fatty liver disease and incident cardiovascular disease Yoshitaka Hashimoto, Masahide Hamaguchi, Takao Kojima et al. · Medicine Open access	May 2017	117
28	Rationale and Evidence for the Use of Oxcarbazepine in Neuropathic Pain Enrique J. Carrazana, Imao Mikoshiba · Journal of Pain and Symptom Management Open access	23 Apr 2003	115
29	Fibrate and Statin Synergistically Increase the Transcriptional Activities of PPARα/RXRα and Decrease the Transactivation of NFκB Ikuo Inoue, Fumiaki Itoh, Shigemi Aoyagi et al. · Biochemical and Biophysical Research Communications	2002	114
30	Inhibition of PDGF- and TGF-β1-induced collagen synthesis, migration and proliferation by tranilast in vascular smooth muscle cells from spontaneously hypertensive rats Keiji Miyazawa, Shinji Kikuchi, Juichi Fukuyama et al. · Atherosclerosis	Dec 1995	108
31	Species differences in the distribution of β‐adrenoceptor subtypes in bladder smooth muscle Yoshinobu Yamazaki, Hiroo Takeda, Masuo Akahane et al. · British Journal of Pharmacology Open access	Jun 1998	106
32	SGLT2 inhibitors: molecular design and potential differences in effect Masayuki Isaji · Kidney International Open access	Mar 2011	105
33	Effect of database profile variation on drug safety assessment: an analysis of spontaneous adverse event reports of Japanese cases Kaori Nomura, Yasushi Hinomura, Genta Kawaguchi et al. · Drug Design Development and Therapy Open access	Jun 2015	104
34	Effects of thromboxane synthetase inhibitors on aggregation of rabbit platelets Jun Naito, Hidetada Komatsu, Arao Ujiie et al. · European Journal of Pharmacology	Jul 1983	101
35	Algorithm for sleep scoring in experimental animals based on fast Fourier transform power spectrum analysis of the electroencephalogram Sayaka Kohtoh, Yujiro Taguchi, Naomi Matsumoto et al. · Sleep and Biological Rhythms	Jul 2008	100
36	Tranilast inhibits the proliferation, chemotaxis and tube formation of human microvascular endothelial cells in vitro and angiogenesis in vivo Masayuki Isaji, Hiroshi Miyata, Yoshiyuki Ajisawa et al. · British Journal of Pharmacology Open access	Nov 1997	100
37	RELAXANT EFFECTS OF ISOPROTERENOL AND SELECTIVE β3-ADRENOCEPTOR AGONISTS ON NORMAL, LOW COMPLIANT AND HYPERREFLEXIC HUMAN BLADDERS Yasuhiko Igawa, Yoshinobu Yamazaki, Hiroo Takeda et al. · The Journal of Urology	2001	99
38	The safety of ustekinumab treatment in patients with moderate-to-severe psoriasis and latent tuberculosis infection Tsen‐Fang Tsai, Vincent C. Ho, Michael W. Song et al. · British Journal of Dermatology	14 Jul 2012	96
39	Orally potent human renin inhibitors derived from angiotensinogen transition state: design, synthesis, and mode of interaction Kinji Iizuka, Tetsuhide Kamijo, Hiromu Harada et al. · Journal of Medicinal Chemistry Open access	Oct 1990	92
40	Hypocholesterolemic effect of buckwheat protein extract in rats fed cholesterol enriched diets Jun Kayashita, Iwao Shimaoka, Misao Nakajyoh · Nutrition Research	May 1995	91
41	CXCR3 Binding Chemokine and TNFSF14 Over Expression in Bladder Urothelium of Patients With Ulcerative Interstitial Cystitis Teruyuki Ogawa, Toshiki Homma, Yasuhiko Igawa et al. · The Journal of Urology	25 Jan 2010	89
42	KMD-3213, a uroselective and long-acting alpha(1a)-adrenoceptor antagonist, tested in a novel rat model. Katsuyoshi Akiyama, Masachiyo Hora, Satoshi Tatemichi et al. · PubMed	Oct 1999	89
43	Which concentration of the inhibitor should be used to predict in vivo drug interactions from in vitro data? Kiyomi Ito, Kōji Chiba, Masato Horikawa et al. · AAPS PharmSci Open access	Dec 2002	87
44	Effect of Grinding with Hydroxypropyl Cellulose on the Dissolution and Particle Size of a Poorly Water-Soluble Drug. Tatsuhiko Yamada, Noriyasu Saito, Teruko Imai et al. · Chemical and Pharmaceutical Bulletin Open access	1999	86
45	Sustained-release of protein from biodegradable sericin film, gel and sponge Ayumu Nishida, Masaki Yamada, Takanori Kanazawa et al. · International Journal of Pharmaceutics	15 Jan 2011	86
46	Sodium-glucose cotransporter inhibitors for diabetes. Masayuki Isaji · PubMed	Apr 2007	86
47	Evaluation of the repeated-dose liver and gastrointestinal tract micronucleus assays with 22 chemicals using young adult rats: Summary of the collaborative study by the Collaborative Study Group for the Micronucleus Test (CSGMT)/The Japanese Environmental Mutagen Society (JEMS) – Mammalian Mutagenicity Study Group (MMS) Shuichi Hamada et al. · Mutation Research/Genetic Toxicology and Environmental Mutagenesis Open access	5 Jan 2015	84
48	Physiological difference between obese (fa/fa) Zucker rats and lean Zucker rats concerning adiponectin Fumiki Oana, Hiroo Takeda, Kohichi Hayakawa et al. · Metabolism	28 Jul 2005	83
49	Effects of the novel immunosuppressant FTY720 in a murine rheumatoid arthritis model Sachi Tsunemi, Tsuyoshi Iwasaki, Sachie Kitano et al. · Clinical Immunology	26 Apr 2010	83
50	Remogliflozin Etabonate Improves Fatty Liver Disease in Diet-Induced Obese Male Mice Shigeru Nakano, Kenji Katsuno, Masayuki Isaji et al. · Journal of Clinical and Experimental Hepatology Open access	28 Apr 2015	82

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.