| 1 |
Perioperative chemotherapy with fluorouracil plus leucovorin, oxaliplatin, and docetaxel versus fluorouracil or capecitabine plus cisplatin and epirubicin for locally advanced, resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4): a randomised, phase 2/3 trial
Salah‐Eddin Al‐Batran et al. · The Lancet
|
11 Apr 2019 |
2,700 |
| 2 |
FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab as first-line treatment for patients with metastatic colorectal cancer (FIRE-3): a randomised, open-label, phase 3 trial
Volker Heinemann et al. · The Lancet Oncology
|
31 Jul 2014 |
1,759 |
| 3 |
Nephron Number in Patients with Primary Hypertension
Gunhild Keller, Gisela Zimmer, Gerhard Mall et al. · New England Journal of Medicine
Open access |
8 Jan 2003 |
1,112 |
| 4 |
Rivaroxaban or Aspirin for Extended Treatment of Venous Thromboembolism
Jeffrey Ian Weitz, Anthonie W.A. Lensing, Martin H. Prins et al. · New England Journal of Medicine
Open access |
18 Mar 2017 |
791 |
| 5 |
Prognostic Value of Fractional Flow Reserve
Nils P. Johnson et al. · Journal of the American College of Cardiology
Open access |
Oct 2014 |
632 |
| 6 |
Tinzaparin vs Warfarin for Treatment of Acute Venous Thromboembolism in Patients With Active Cancer
Agnes Y. Y. Lee, Pieter Willem Kamphuisen, Guy Meyer et al. · JAMA
Open access |
18 Aug 2015 |
615 |
| 7 |
International clinical practice guidelines for the treatment and prophylaxis of venous thromboembolism in patients with cancer
Dominique Farge et al. · Journal of Thrombosis and Haemostasis
Open access |
11 Dec 2012 |
596 |
| 8 |
A randomized multicentre trial to compare revascularization with optimal medical therapy for the treatment of chronic total coronary occlusions
Gerald S. Werner et al. · European Heart Journal
Open access |
4 Apr 2018 |
588 |
| 9 |
Oral rivaroxaban versus standard therapy for the treatment of symptomatic venous thromboembolism: a pooled analysis of the EINSTEIN-DVT and PE randomized studies
Martin H. Prins, Anthonie WA Lensing, Rupert Martin Bauersachs et al. · Thrombosis Journal
Open access |
2013 |
555 |
| 10 |
Focused echocardiographic evaluation in life support and peri-resuscitation of emergency patients: A prospective trial
Raoul Breitkreutz, Susanna Price, Holger V. Steiger et al. · Resuscitation
|
Sep 2010 |
518 |
| 11 |
Guiding Principles for Chronic Total Occlusion Percutaneous Coronary Intervention
Emmanouil S. Brilakis et al. · Circulation
Open access101 authors |
29 Jul 2019 |
460 |
| 12 |
Burden of Coronary Artery Disease and Peripheral Artery Disease: A Literature Review
Rupert Martin Bauersachs, Uwe Zeymer, J Brière et al. · Cardiovascular Therapeutics
Open access |
26 Nov 2019 |
451 |
| 13 |
The pathophysiology of endometriosis and adenomyosis: tissue injury and repair
GERHARD LEYENDECKER, L. Wildt, Gaganpreet K. Mall · Archives of Gynecology and Obstetrics
Open access |
30 Jul 2009 |
422 |
| 14 |
World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Schizophrenia, Part 2: Update 2012 on the long-term treatment of schizophrenia and management of antipsychotic-induced side effects
Alkomiet Hasan, Peter Falkai, Thomas Wobrock et al. · The World Journal of Biological Psychiatry
|
6 Dec 2012 |
422 |
| 15 |
The dynamics of rapid sperm transport through the female genital tract: evidence from vaginal sonography of uterine peristalsis and hysterosalpingoscintigraphy
Georg Kunz, D. Beil, Heinz K. Deininger et al. · Human Reproduction
|
Mar 1996 |
409 |
| 16 |
Diagnosis and management of acute deep vein thrombosis: a joint consensus document from the European Society of Cardiology working groups of aorta and peripheral vascular diseases and pulmonary circulation and right ventricular function
Lucia Mazzolai, Victor Aboyans, Walter Ageno et al. · European Heart Journal
Open access |
30 Jan 2017 |
405 |
| 17 |
Fondaparinux for the Treatment of Superficial-Vein Thrombosis in the Legs
Hervé Decousus, Paolo Prandoni, Patrick Mismetti et al. · New England Journal of Medicine
Open access |
22 Sep 2010 |
398 |
| 18 |
Incidence and prevalence of atrial fibrillation: an analysis based on 8.3 million patients
Thomas Wilke, Ashley Groth, S. Mueller et al. · EP Europace
Open access |
6 Dec 2012 |
398 |
| 19 |
Survival of Functionally Anuric Patients on Automated Peritoneal Dialysis
Edwina Anne Brown, Simon Davies, Peter A. Rutherford et al. · Journal of the American Society of Nephrology
|
Nov 2003 |
380 |
| 20 |
Impact of treatment delay on mortality in ST-segment elevation myocardial infarction (STEMI) patients presenting with and without haemodynamic instability: results from the German prospective, multicentre FITT-STEMI trial
Karl Heinrich Scholz, Sebastian K.G. Maier, Lars Siegfried Maier et al. · European Heart Journal
Open access |
18 Jan 2018 |
377 |
| 21 |
Adenomyosis in endometriosis—prevalence and impact on fertility. Evidence from magnetic resonance imaging
Georg Kunz, D. Beil, Peter E. Huppert et al. · Human Reproduction
Open access |
27 May 2005 |
375 |
| 22 |
International clinical practice guidelines for the treatment and prophylaxis of thrombosis associated with central venous catheters in patients with cancer
Philippe M Debourdeau et al. · Journal of Thrombosis and Haemostasis
Open access |
11 Dec 2012 |
324 |
| 23 |
Definitions and Clinical Trial Design Principles for Coronary Artery Chronic Total Occlusion Therapies: CTO-ARC Consensus Recommendations
Luiz F. Ybarra et al. · Circulation
Open access |
2 Feb 2021 |
311 |
| 24 |
Uterine hyperperistalsis and dysperistalsis as dysfunctions of the mechanism of rapid sperm transport in patients with endometriosis and infertility
GERHARD LEYENDECKER, Georg Kunz, L. Wildt et al. · Human Reproduction
|
Jul 1996 |
309 |
| 25 |
Endometriosis results from the dislocation of basal endometrium
GERHARD LEYENDECKER · Human Reproduction
|
26 Sep 2002 |
300 |
| 26 |
Granulocyte-macrophage-colony-stimulating factor enhances immune responses to melanoma-associated peptidesin vivo
Elke J�ger, Mark Ringhoffer, Hans Peter Dienes et al. · International Journal of Cancer
|
3 Jul 1996 |
297 |
| 27 |
Meta-analysis in metastatic uveal melanoma to determine progression free and overall survival benchmarks: an international rare cancers initiative (IRCI) ocular melanoma study
Leila Khoja et al. · Annals of Oncology
Open access |
28 May 2019 |
291 |
| 28 |
Cardiac Involvement in Churg-Strauss Syndrome
Thomas E. Neumann, Bernhard Manger, Michael Schmid et al. · Medicine
|
Jul 2009 |
264 |
| 29 |
Adenomyosis and endometriosis. Re-visiting their association and further insights into the mechanisms of auto-traumatisation. An MRI study
GERHARD LEYENDECKER, A. Bilgicyildirim, M. Inacker et al. · Archives of Gynecology and Obstetrics
Open access |
20 Sep 2014 |
262 |
| 30 |
Effect of Osocimab in Preventing Venous Thromboembolism Among Patients Undergoing Knee Arthroplasty
Jeffrey Ian Weitz, Rupert Martin Bauersachs, Bastian Becker et al. · JAMA
Open access |
14 Jan 2020 |
258 |
| 31 |
Hidradenitis suppurativa/acne inversa: a practical framework for treatment optimization – systematic review and recommendations from the HS ALLIANCE working group
Christos C. Zouboulis, Falk G. Bechara, Janine L. Dickinson-Blok et al. · Journal of the European Academy of Dermatology and Venereology
ReviewOpen access |
3 Sep 2018 |
257 |
| 32 |
Global Chronic Total Occlusion Crossing Algorithm
Eugene Brian Wu et al. · Journal of the American College of Cardiology
Open access125 authors |
Aug 2021 |
244 |
| 33 |
Generation of cytotoxic T-cell responses with synthetic melanoma-associated peptidesin vivo: Implications for tumor vaccines with melanoma-associated antigens
Elke Jaeger, Helga Bernhard, Pedro J. Romero et al. · International Journal of Cancer
|
10 Apr 1996 |
244 |
| 34 |
Retrograde Recanalization of Chronic Total Occlusions in Europe
Alfredo Ruggero Galassi et al. · Journal of the American College of Cardiology
Open access |
Jun 2015 |
240 |
| 35 |
Best supportive care and therapeutic plasma exchange with or without eculizumab in Shiga-toxin-producing E. coli O104:H4 induced haemolytic–uraemic syndrome: an analysis of the German STEC-HUS registry
Jan Thomas Kielstein et al. · Nephrology Dialysis Transplantation
|
Oct 2012 |
239 |
| 36 |
Multisite prediction of 4-week and 52-week treatment outcomes in patients with first-episode psychosis: a machine learning approach
Nikolaos Koutsouleris, René S. Kahn, Adam Mourad Chekroud et al. · The Lancet Psychiatry
Open access |
31 Aug 2016 |
231 |
| 37 |
The cyclic pattern of the immunocytochemical expression of oestrogen and progesterone receptors in human myometrial and endometrial layers: characterization of the endometrialsubendometrial unit
M. Noe · Human Reproduction
|
1999 |
217 |
| 38 |
S3-Leitlinie zum exokrinen Pankreaskarzinom
Thomas Theodor Werner Seufferlein et al. · Zeitschrift für Gastroenterologie
Open access |
11 Dec 2013 |
216 |
| 39 |
A phase I/IIa study of the mRNA-based cancer immunotherapy CV9201 in patients with stage IIIB/IV non-small cell lung cancer
Martin Sebastian et al. · Cancer Immunology Immunotherapy
Open access |
15 Feb 2019 |
213 |
| 40 |
Dermatofibrosarcoma protuberans: Wide local excision vs. Mohs micrographic surgery
Andrea Paradisi, DAMIANO D ABENI, Antonio Rusciani et al. · Cancer Treatment Reviews
|
6 Aug 2008 |
211 |
| 41 |
Uterine peristaltic activity during the menstrual cycle: characterization, regulation, function and dysfunction
Georg Kunz, GERHARD LEYENDECKER · Reproductive BioMedicine Online
|
2002 |
204 |
| 42 |
Endometriosis: a dysfunction and disease of the archimetra
GERHARD LEYENDECKER · Human Reproduction Update
|
Sep 1998 |
200 |
| 43 |
The functional reserve of collaterals supplying long-term chronic total coronary occlusions in patients without prior myocardial infarction
Gerald S. Werner, Ralf Surber, Markus Wolfgang Ferrari et al. · European Heart Journal
|
4 Sep 2006 |
194 |
| 44 |
Phase II Trial of Biweekly Infusional Fluorouracil, Folinic Acid, and Oxaliplatin in Patients With Advanced Gastric Cancer
Salah‐Eddin Al‐Batran, Akin Atmaca, Susanna Hegewisch‐Becker et al. · Journal of Clinical Oncology
Open access |
14 Feb 2004 |
184 |
| 45 |
Therapeutic Hypothermia and the Risk of Infection
Marjolein Geurts, Malcolm Robert Macleod, Rainer Kollmar et al. · Critical Care Medicine
|
29 Aug 2013 |
180 |
| 46 |
Structural abnormalities of the uterine wall in women with endometriosis and infertility visualized by vaginal sonography and magnetic resonance imaging
Georg Kunz, D. Beil, Peter E. Huppert et al. · Human Reproduction
|
2000 |
180 |
| 47 |
Prevention of thromboembolic complications in patients with superficial-vein thrombosis given rivaroxaban or fondaparinux: the open-label, randomised, non-inferiority SURPRISE phase 3b trial
Jan Beyer‐Westendorf, SEBASTIAN M. SCHELLONG, Horst Eberhard Gerlach et al. · The Lancet Haematology
|
16 Feb 2017 |
177 |
| 48 |
Left Prefrontal High-Frequency Repetitive Transcranial Magnetic Stimulation for the Treatment of Schizophrenia with Predominant Negative Symptoms: A Sham-Controlled, Randomized Multicenter Trial
Thomas Wobrock, Birgit Guse, Joachim Cordes et al. · Biological Psychiatry
|
23 Oct 2014 |
174 |
| 49 |
Proteome analysis of human substantia nigra in Parkinson's disease
Cornelius Johannes Werner, Roland Heyny‐von Haußen, Gerhard Mall et al. · Proteome Science
Open access |
2008 |
171 |
| 50 |
Novel splice donor site mutation in the cardiac myosin-binding protein-C gene in familial hypertrophic cardiomyopathy. Characterization Of cardiac transcript and protein.
Wolfgang Rottbauer, Mathias Gautel, Jörg Zehelein et al. · Journal of Clinical Investigation
Open access |
15 Jul 1997 |
169 |