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FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab as first-line treatment for patients with metastatic colorectal cancer (FIRE-3): a randomised, open-label, phase 3 trial
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31 Jul 2014 |
1,759 |
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Bendamustine plus rituximab versus CHOP plus rituximab as first-line treatment for patients with indolent and mantle-cell lymphomas: an open-label, multicentre, randomised, phase 3 non-inferiority trial
Mathias Rummel, N. Niederle, Georg Maschmeyer et al. · The Lancet
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19 Feb 2013 |
1,515 |
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Randomised trial of irinotecan versus fluorouracil by continuous infusion after fluorouracil failure in patients with metastatic colorectal cancer
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995 |
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Efficacy and safety of balloon kyphoplasty compared with non-surgical care for vertebral compression fracture (FREE): a randomised controlled trial
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25 Feb 2009 |
843 |
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Natalizumab for Active Crohn's Disease
Subrata K. Ghosh, Eran Goldin, Fiona H. Gordon et al. · New England Journal of Medicine
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2003 |
814 |
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COSMO-RS: An Alternative to Simulation for Calculating Thermodynamic Properties of Liquid Mixtures
Andreas Klamt, Frank Eckert, Wolfgang Arlt · Annual Review of Chemical and Biomolecular Engineering
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11 Jun 2010 |
621 |
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Spectrum and prognostic relevance of driver gene mutations in acute myeloid leukemia
Klaus Hans Metzeler et al. · Blood
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11 Jun 2016 |
542 |
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Balloon kyphoplasty versus non-surgical fracture management for treatment of painful vertebral body compression fractures in patients with cancer: a multicentre, randomised controlled trial
James R. Berenson, Robert Pflugmacher, Peter F. Jarzem et al. · The Lancet Oncology
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17 Feb 2011 |
526 |
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Avoidance of mechanical ventilation by surfactant treatment of spontaneously breathing preterm infants (AMV): an open-label, randomised, controlled trial
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30 Sep 2011 |
475 |
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Addition of sorafenib versus placebo to standard therapy in patients aged 60 years or younger with newly diagnosed acute myeloid leukaemia (SORAML): a multicentre, phase 2, randomised controlled trial
Christoph Röllig et al. · The Lancet Oncology
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5 Nov 2015 |
404 |
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Crohn's Disease and Escherichia coli
Helmut A. Malchow · Journal of Clinical Gastroenterology
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402 |
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The COSMO and COSMO‐RS solvation models
Andreas Klamt · Wiley Interdisciplinary Reviews Computational Molecular Science
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28 Sep 2017 |
387 |
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Nonintubated Surfactant Application vs Conventional Therapy in Extremely Preterm Infants
Angela Kribs, Claudia Roll, Wolfgang Göpel et al. · Archives of Pediatrics and Adolescent Medicine
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8 Jun 2015 |
374 |
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Prospective evaluation of complications in outpatient GI endoscopy: A survey among German gastroenterologists
Andreas Sieg, Ulrike Hachmoeller-Eisenbach, Thomas Eisenbach · Gastrointestinal Endoscopy
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May 2001 |
335 |
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Impact of Physical Activity on Glycemic Control and Prevalence of Cardiovascular Risk Factors in Adults With Type 1 Diabetes: A Cross-sectional Multicenter Study of 18,028 Patients
Barbara Bohn, Antje Herbst, M. Pfeifer et al. · Diabetes Care
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26 May 2015 |
322 |
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Development of new auxiliary basis functions of the Karlsruhe segmented contracted basis sets including diffuse basis functions (def2-SVPD, def2-TZVPPD, and def2-QVPPD) for RI-MP2 and RI-CC calculations
Arnim Hellweg, Dmitrij Rappoport · Physical Chemistry Chemical Physics
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19 Nov 2014 |
316 |
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Oral budesonide for prevention of postsurgical recurrence in Crohn's disease
Goran Hellers, Antoine Cortot, Derek P. Jewell et al. · Gastroenterology
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Feb 1999 |
300 |
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Diabetic Nephropathy in 27,805 Children, Adolescents, and Adults With Type 1 Diabetes
Klemens Raile, Angela Galler, Sabine E. Hofer et al. · Diabetes Care
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28 Sep 2007 |
282 |
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Balloon kyphoplasty for the treatment of acute vertebral compression fractures: 2-year results from a randomized trial
Steven Boonen, Jan Van Meirhaeghe, Leonard Bastian et al. · Journal of Bone and Mineral Research
Open access |
17 Feb 2011 |
233 |
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Diagnosis of Bacteremia in Whole-Blood Samples by Use of a Commercial Universal 16S rRNA Gene-Based PCR and Sequence Analysis
Nele Wellinghausen, Anna-Julia Kochem, Claudia Disqué et al. · Journal of Clinical Microbiology
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2 Jul 2009 |
226 |
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Safety assessment in development and operation of modular continuous-flow processes
Norbert Kockmann, Philipp Thenée, Christoph Fleischer‐Trebes et al. · Reaction Chemistry & Engineering
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225 |
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Strategies to enhance rational use of antibiotics in hospital: a guideline by the German Society for Infectious Diseases
Katja de With et al. · Infection
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11 Apr 2016 |
217 |
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Patterns of multisite pain and associations with risk factors
David Coggon et al. · Pain
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29 May 2013 |
197 |
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Fat composition may be a clue to explain the primary therapeutic effect of enteral nutrition in Crohn's disease: results of a double blind randomised multicentre European trial
M.À. Gassull, Fernando Fernández‐Bañares, E. Cabré et al. · Gut
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28 Jul 2002 |
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Validation and refinement of the revised 2017 European LeukemiaNet genetic risk stratification of acute myeloid leukemia
Tobias Herold et al. · Leukemia
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30 Mar 2020 |
192 |
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Absence of efficacy of subcutaneous antisense ICAM-1 treatment of chronic active Crohn's disease
Stefan Schreiber, Susanna Nikolaus, H Malchow et al. · Gastroenterology
Open access |
May 2001 |
189 |
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Effect of Monitoring Bone Turnover Markers on Persistence with Risedronate Treatment of Postmenopausal Osteoporosis
Pierre Dominique Delmas, Bernard Vrijens, Richard Eastell et al. · The Journal of Clinical Endocrinology & Metabolism
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24 Jan 2007 |
186 |
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Disabling musculoskeletal pain in working populations: Is it the job, the person, or the culture?
David Coggon et al. · Pain
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18 May 2013 |
180 |
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The CUPID (Cultural and Psychosocial Influences on Disability) Study: Methods of Data Collection and Characteristics of Study Sample
David Coggon et al. · PLoS ONE
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6 Jul 2012 |
178 |
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Indications for cardiovascular magnetic resonance in children with congenital and acquired heart disease: an expert consensus paper of the Imaging Working Group of the AEPC and the Cardiovascular Magnetic Resonance Section of the EACVI
Emanuela R. Valsangiacomo Buechel et al. · European Heart Journal - Cardiovascular Imaging
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17 Feb 2015 |
176 |
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CEBPA mutations in 4708 patients with acute myeloid leukemia: differential impact of bZIP and TAD mutations on outcome
Franziska Taube et al. · Blood
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28 Jul 2021 |
174 |
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Comparative effects of teriparatide and risedronate in glucocorticoid-induced osteoporosis in men: 18-month results of the EuroGIOPs trial
Claus‐C. Glüer et al. · Journal of Bone and Mineral Research
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15 Jan 2013 |
174 |
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Intermittent intravenous ibandronate injections reduce vertebral fracture risk in corticosteroid-induced osteoporosis: results from a long-term comparative study
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Efficacy of risedronate in men with primary and secondary osteoporosis: results of a 1-year study
Johann Diederich Ringe, Herbert Faber, Parvis Farahmand et al. · Rheumatology International
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6 Jul 2005 |
169 |
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Prävention, Diagnostik, Therapie und Nachsorge des Lungenkarzinoms
Gerd Goeckenjan et al. · Pneumologie
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Mar 2010 |
166 |
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Future Production Concepts in the Chemical Industry: Modular – Small‐Scale – Continuous
Thomas Bieringer, Sigurd Buchholz, Norbert Kockmann · Chemical Engineering & Technology
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13 May 2013 |
166 |
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Infection Reduction Using Antibiotic-Coated Inflatable Penile Prosthesis
Steven K. Wilson, Jürgen Zumbe, Gerard D. Henry et al. · Urology
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Aug 2007 |
163 |
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Impact of storage conditions and storage time on silver nanoparticles' physicochemical properties and implications for their biological effects
Emilia Izak‐Nau, Anna Huk, Brian Reidy et al. · RSC Advances
Open access |
2015 |
162 |
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Solubility prediction, solvate and cocrystal screening as tools for rational crystal engineering
Christoph Loschen, Andreas Klamt · Journal of Pharmacy and Pharmacology
Open access |
8 Apr 2015 |
162 |
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Inborn errors in RNA polymerase III underlie severe varicella zoster virus infections
Benson Ogunjimi et al. · Journal of Clinical Investigation
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6 Aug 2017 |
160 |
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Laparoscopic Radical Prostatectomy - the Experience of the German Laparoscopic Working Group
Jens Jochen Rassweiler, Jens Uwe Stolzenburg, Tullio Sulser et al. · European Urology
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3 Nov 2005 |
159 |
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Origin, evolution, and global transmission of community-acquired Staphylococcus aureus ST8
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20 Nov 2017 |
157 |
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Bendamustine Plus Rituximab Is Superior in Respect of Progression Free Survival and CR Rate When Compared to CHOP Plus Rituximab as First-Line Treatment of Patients with Advanced Follicular, Indolent, and Mantle Cell Lymphomas: Final Results of a Randomized Phase III Study of the StiL (Study Group Indolent Lymphomas, Germany).
Mathias Rummel, N. Niederle, Georg Maschmeyer et al. · Blood
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157 |
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Developing the biofacility of the future based on continuous processing and single-use technology
Stephan Klutz, Jørgen Barsett Magnus, Martin Lobedann et al. · Journal of Biotechnology
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16 Jun 2015 |
156 |
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Bendamustine plus rituximab versus fludarabine plus rituximab for patients with relapsed indolent and mantle-cell lymphomas: a multicentre, randomised, open-label, non-inferiority phase 3 trial
Mathias Rummel, Ulrich Kaiser, Christina Balser et al. · The Lancet Oncology
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4 Dec 2015 |
155 |
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Mesalamine Once Daily Is More Effective Than Twice Daily in Patients With Quiescent Ulcerative Colitis
Axel U Dignass, Bernd Bokemeyer, Henning Ernst Adamek et al. · Clinical Gastroenterology and Hepatology
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17 Apr 2009 |
154 |
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COSMOSPACE: Alternative to conventional activity‐coefficient models
Andreas Klamt, Gerard J. P. Krooshof, Ross Taylor · AIChE Journal
Open access |
Oct 2002 |
151 |
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A Randomized Trial of Balloon Kyphoplasty and Nonsurgical Management for Treating Acute Vertebral Compression Fractures
Jan Van Meirhaeghe, Leonard Bastian, Steven Boonen et al. · Spine
Open access |
27 Feb 2013 |
151 |
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Prevention, Diagnosis, Therapy, and Follow-up of Lung Cancer
Gerd Goeckenjan et al. · Pneumologie
Open access |
14 Dec 2010 |
150 |
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COSMO-RS: A novel view to physiological solvation and partition questions
Andreas Klamt, Frank Eckert, Martin Hornig · Journal of Computer-Aided Molecular Design
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Apr 2001 |
143 |