Institution · Kobe Pharmaceutical University

Most cited papers from Kobe Pharmaceutical University

Kobe Pharmaceutical University

What are the most cited papers from Kobe Pharmaceutical University?

The most cited paper from Kobe Pharmaceutical University is "Raptor, a Binding Partner of Target of Rapamycin (TOR), Mediates TOR Action" (Kenta Hara, Yoshiko Maruki, Samuel Long et al., 2002), with 1,814 citations. Next come "Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine" (778) and "Recent advances in the structural biology of chondroitin sulfate and dermatan sulfate" (692).

Published TypeFieldAccessCitations

Showing 50 of 61 papers. Every paper with more than 158 citations is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	Raptor, a Binding Partner of Target of Rapamycin (TOR), Mediates TOR Action Kenta Hara, Yoshiko Maruki, Samuel Long et al. · Cell Open access	Jul 2002	1,814
2	Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine Kook Hwan Kim et al. · Nature Medicine	2 Dec 2012	778
3	Recent advances in the structural biology of chondroitin sulfate and dermatan sulfate Kazuyuki Sugahara, Tadahisa Mikami, Toru Uyama et al. · Current Opinion in Structural Biology Review	Oct 2003	692
4	Biosynthesis and function of chondroitin sulfate Tadahisa Mikami, Hiroshi Kitagawa · Biochimica et Biophysica Acta (BBA) - General Subjects	14 Jun 2013	503
5	Casting a Wide Net: Role of Perineuronal Nets in Neural Plasticity Barbara A. Sorg, Sabina Berretta, Jordan M. Blacktop et al. · Journal of Neuroscience Open access	9 Nov 2016	484
6	Recent advances in the study of the biosynthesis and functions of sulfated glycosaminoglycans Kazuyuki Sugahara, Hiroshi Kitagawa · Current Opinion in Structural Biology Review	Oct 2000	433
7	Endothelial Cell–Derived Endothelin-1 Promotes Cardiac Fibrosis in Diabetic Hearts Through Stimulation of Endothelial-to-Mesenchymal Transition Bambang Widyantoro, Noriaki Emoto, Kazuhiko Nakayama et al. · Circulation	24 May 2010	386
8	Supplementation of hydrogen-rich water improves lipid and glucose metabolism in patients with type 2 diabetes or impaired glucose tolerance Sizuo Kajiyama, Goji Hasegawa, Mai Asano et al. · Nutrition Research	Mar 2008	383
9	Persistent cortical plasticity by upregulation of chondroitin 6-sulfation Shinji Miyata, Yukio Komatsu, Yumiko Yoshimura et al. · Nature Neuroscience	15 Jan 2012	378
10	Composition of Perineuronal Net Extracellular Matrix in Rat Brain Sarama Sathyaseelan Deepa, Daniela Carulli, Clare M. Galtrey et al. · Journal of Biological Chemistry Open access	27 Apr 2006	376
11	Nationwide Survey on Complementary and Alternative Medicine in Cancer Patients in Japan Ichinosuke Hyodo, Noriko Amano, Kenji Eguchi et al. · Journal of Clinical Oncology Open access	23 Feb 2005	347
12	Mechanism of ATP-binding Cassette Transporter A1-mediated Cellular Lipid Efflux to Apolipoprotein A-I and Formation of High Density Lipoprotein Particles Charulatha Vedhachalam, Phu Duong, Margaret Nickel et al. · Journal of Biological Chemistry Open access	30 Jun 2007	340
13	Specific Molecular Interactions of Oversulfated Chondroitin Sulfate E with Various Heparin-binding Growth Factors Sarama Sathyaseelan Deepa, Yuko Umehara, Shigeki Higashiyama et al. · Journal of Biological Chemistry Open access	Nov 2002	330
14	MDR1 Genotype-Related Pharmacokinetics of Digoxin After Single Oral Administration in Healthy Japanese Subjects Toshiyuki Sakaeda, Tsutomu Nakamura, Masanori Horinouchi et al. · Pharmaceutical Research	Oct 2001	322
15	Identification of UBIAD1 as a novel human menaquinone-4 biosynthetic enzyme Kimie Nakagawa, Yoshihisa Hirota, Natsumi Sawada et al. · Nature	15 Oct 2010	319
16	Mechanism of recipient cell-dependent differences in exosome uptake Sayo Horibe, Toshihito Tanahashi, Shoji Kawauchi et al. · BMC Cancer Open access	6 Jan 2018	291
17	Zinc-releasing calcium phosphate for stimulating bone formation Atsuo Ito, Haruo Kawamura, Makoto Otsuka et al. · Materials Science and Engineering C	Oct 2002	283
18	Chondroitin/dermatan sulfate in the central nervous system Kazuyuki Sugahara, Tadahisa Mikami · Current Opinion in Structural Biology Review	Oct 2007	274
19	Dual Roles of Astrocyte-Derived Factors in Regulation of Blood-Brain Barrier Function after Brain Damage Shotaro Michinaga, Yutaka Kōyama · International Journal of Molecular Sciences Open access	29 Jan 2019	269
20	Higher radical scavenging activities of polyphenolic antioxidants can be ascribed to chemical reactions following their oxidation Hiroki Hotta, Satomi Nagano, Masashi Ueda et al. · Biochimica et Biophysica Acta (BBA) - General Subjects	Aug 2002	265
21	Depressed expression of Klotho and FGF receptor 1 in hyperplastic parathyroid glands from uremic patients Hirotaka Komaba, Shunsuke Goto, Hideki Fujii et al. · Kidney International Open access	4 Nov 2009	265
22	Conversion of Phylloquinone (Vitamin K1) into Menaquinone-4 (Vitamin K2) in Mice Toshio Okano, Yuka Shimomura, Makiko Yamane et al. · Journal of Biological Chemistry Open access	15 Dec 2007	262
23	Chondroitin proteoglycans are involved in cell division of Caenorhabditis elegans Souhei Mizuguchi, Toru Uyama, Hiroshi Kitagawa et al. · Nature	May 2003	261
24	Intercalation of amino acids and peptides into Mg–Al layered double hydroxide by reconstruction method Hirokazu Nakayama, Natsuko Wada, Mitsutomo Tsuhako · International Journal of Pharmaceutics	10 Dec 2003	258
25	Chk1 Is a Histone H3 Threonine 11 Kinase that Regulates DNA Damage-Induced Transcriptional Repression Midori Shimada, Hiroyuki Niida, Doaa Hussein Zineldeen et al. · Cell Open access	2008	256
26	Heparin and Heparan Sulfate Biosynthesis Kazuyuki Sugahara, Hiroshi Kitagawa · IUBMB Life	Oct 2002	255
27	Oversulfated Chondroitin/Dermatan Sulfates Containing GlcAβ1/IdoAα1–3GalNAc(4,6-O-disulfate) Interact with L- and P-selectin and Chemokines Hiroto Kawashima, Kazuyuki Atarashi, Mayumi Hirose et al. · Journal of Biological Chemistry Open access	Apr 2002	238
28	UV-Sensitive Photoreceptor Protein OPN5 in Humans and Mice Daisuke Kojima, Suguru Mori, Masaki Torii et al. · PLoS ONE Open access	17 Oct 2011	233
29	Solid-state NMR spectroscopy structure determination of a lipid-embedded heptahelical membrane protein Shenlin Wang, Rachel A. Munro, Lichi Shi et al. · Nature Methods	6 Sep 2013	232
30	Microanalysis of Glycosaminoglycan-Derived Oligosaccharides Labeled with a Fluorophore 2-Aminobenzamide by High-Performance Liquid Chromatography: Application to Disaccharide Composition Analysis and Exosequencing of Oligosaccharides Akiko Kinoshita, Kazuyuki Sugahara · Analytical Biochemistry	May 1999	213
31	Secondary metabolites in plants: transport and self-tolerance mechanisms Nobukazu Shitan · Bioscience Biotechnology and Biochemistry Open access	4 Mar 2016	207
32	Molecular Cloning and Expression of a Human Chondroitin Synthase Hiroshi Kitagawa, Toru Uyama, Kazuyuki Sugahara · Journal of Biological Chemistry Open access	Oct 2001	206
33	The Tumor Suppressor EXT-like Gene EXTL2 Encodes an α1, 4-N-Acetylhexosaminyltransferase That TransfersN-Acetylgalactosamine and N-Acetylglucosamine to the Common Glycosaminoglycan-Protein Linkage Region Hiroshi Kitagawa, Hiromi Shimakawa, Kazuyuki Sugahara · Journal of Biological Chemistry Open access	May 1999	203
34	Relationships Among Carbonated Apatite Solubility, Crystallite Size, and Microstrain Parameters Arif A Baig, J.L. Fox, RICHARD A. YOUNG et al. · Calcified Tissue International	May 1999	200
35	Efficacy of long-term ezetimibe therapy in patients with nonalcoholic fatty liver disease Hyohun Park, Toshihide Shima, Kanji Yamaguchi et al. · Journal of Gastroenterology	23 Jul 2010	197
36	Loss of chondroitin 6- O -sulfotransferase-1 function results in severe human chondrodysplasia with progressive spinal involvement Hölger Thiele, Masahiro Sakano, Hiroshi Kitagawa et al. · Proceedings of the National Academy of Sciences Open access	23 Jun 2004	193
37	Heparan/Chondroitin Sulfate Biosynthesis Lars Christian Pedersen, Kazunori Tsuchida, Hiroshi Kitagawa et al. · Journal of Biological Chemistry Open access	Nov 2000	190
38	Chondroitin 6‐sulphate synthesis is up‐regulated in injured CNS, induced by injury‐related cytokines and enhanced in axon‐growth inhibitory glia G. Properzi, Daniela Carulli, Richard A. Asher et al. · European Journal of Neuroscience	2005	186
39	Chondroitin Sulfate Chains on Syndecan-1 and Syndecan-4 from Normal Murine Mammary Gland Epithelial Cells Are Structurally and Functionally Distinct and Cooperate with Heparan Sulfate Chains to Bind Growth Factors Sarama Sathyaseelan Deepa, Shuhei Yamada, Masahiro Zako et al. · Journal of Biological Chemistry Open access	28 Jun 2004	186
40	Developmental Regulation of the Sulfation Profile of Chondroitin Sulfate Chains in the Chicken Embryo Brain Hiroshi Kitagawa, Kae Tsutsumi, Yuko Tone et al. · Journal of Biological Chemistry Open access	Dec 1997	186
41	Formation and remodeling of the brain extracellular matrix in neural plasticity: Roles of chondroitin sulfate and hyaluronan Shinji Miyata, Hiroshi Kitagawa · Biochimica et Biophysica Acta (BBA) - General Subjects	16 Jun 2017	182
42	Human tumor suppressor EXT gene family members EXTL1 and EXTL3 encode α1,4- N -acetylglucosaminyltransferases that likely are involved in heparan sulfate/ heparin biosynthesis Byung‐Taek Kim, Hiroshi Kitagawa, Jun‐ichi Tamura et al. · Proceedings of the National Academy of Sciences Open access	5 Jun 2001	179
43	The DSD-1 Carbohydrate Epitope Depends on Sulfation, Correlates with Chondroitin Sulfate D Motifs, and Is Sufficient to Promote Neurite Outgrowth Albrecht Martin Clement, Satomi Nadanaka, Kimiko Masayama et al. · Journal of Biological Chemistry Open access	Oct 1998	177
44	Molecular Cloning and Expression of Glucuronyltransferase I Involved in the Biosynthesis of the Glycosaminoglycan-Protein Linkage Region of Proteoglycans Hiroshi Kitagawa, Yuko Tone, Jun‐ichi Tamura et al. · Journal of Biological Chemistry Open access	Mar 1998	177
45	Convalescent COVID-19 patients are susceptible to endothelial dysfunction due to persistent immune activation Florence WJ Chioh, Siew‐Wai Fong, Barnaby Edward Young et al. · eLife Open access	22 Mar 2021	171
46	Glycosaminoglycan modification of neuropilin‐1 modulates VEGFR2 signaling Yasunori Shintani, Seiji Takashima, Yoshihiro Asano et al. · The EMBO Journal Open access	8 Jun 2006	171
47	The EXT1/EXT2 tumor suppressors: catalytic activities and role in heparan sulfate biosynthesis Claire Senay, Thomas Lind, Kumi Muguruma et al. · EMBO Reports Open access	Sep 2000	170
48	Resolvin E1, an endogenous lipid mediator derived from eicosapentaenoic acid, prevents dextran sulfate sodium–induced colitis Tsukasa Ishida, Masaru Yoshida, Makoto Arita et al. · Inflammatory Bowel Diseases Open access	Jul 2009	170
49	Molecular Cloning and Characterization of CYP80G2, a Cytochrome P450 That Catalyzes an Intramolecular C–C Phenol Coupling of (S)-Reticuline in Magnoflorine Biosynthesis, from Cultured Coptis japonica Cells Nobuhiro Ikezawa, Kinuko Iwasa, Fumihiko Sato · Journal of Biological Chemistry Open access	29 Jan 2008	169
50	Molecular Cloning of a Chondroitin Polymerizing Factor That Cooperates with Chondroitin Synthase for Chondroitin Polymerization Hiroshi Kitagawa, Tomomi Izumikawa, Toru Uyama et al. · Journal of Biological Chemistry Open access	Jun 2003	168

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.