Most cited papers from Kumamoto University

Kumamoto University

What are the most cited papers from Kumamoto University?

The most cited paper from Kumamoto University is "Evaluation of Factors Related to Late Recurrence - Later than 10 Years after the Initial Treatment - in Primary Breast Cancer" (Reiki Nishimura, Tomofumi Osako, Yasuyuki Nishiyama et al., 2013), with 13,212 citations. Next come "A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs." (6,800) and "Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review" (6,577).

Published TypeFieldAccessAuthorsCitations

Showing 50 of 60 papers. Every paper with more than 913 citations is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	Evaluation of Factors Related to Late Recurrence - Later than 10 Years after the Initial Treatment - in Primary Breast Cancer Reiki Nishimura, Tomofumi Osako, Yasuyuki Nishiyama et al. · Oncology Open access	2013	13,212
2	A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs. Yasuhiro Matsumura, Hiroshi Maeda · PubMed	Dec 1986	6,800
3	Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review Hiroshi Maeda, Jun Wu, Tomohiro Sawa et al. · Journal of Controlled Release	Mar 2000	6,577
4	Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) Daniel J. Klionsky et al. · Autophagy Open access2,467 authors	2 Jan 2016	6,023
5	Efficient selection for high-expression transfectants with a novel eukaryotic vector Hitoshi Niwa, Ken‐ichi Yamamura, Jun‐ichi Miyazaki · Gene	Dec 1991	5,233
6	Mutation of the mouse klotho gene leads to a syndrome resembling ageing Makoto Kuro‐o, Yutaka Matsumura, Hiroki Aizawa et al. · Nature	6 Nov 1997	3,876
7	Intensive insulin therapy prevents the progression of diabetic microvascular complications in Japanese patients with non-insulin-dependent diabetes mellitus: a randomized prospective 6-year study Yasuo Ohkubo, Hideki Kishikawa, Eiichi Araki et al. · Diabetes Research and Clinical Practice	May 1995	3,105
8	Roles of CHOP/GADD153 in endoplasmic reticulum stress Seiichi Oyadomari, Masataka Mori · Cell Death and Differentiation	19 Dec 2003	2,860
9	Distinct Sets of Genetic Alterations in Melanoma John A. Curtin, Jane Fridlyand, Toshiro Kageshita et al. · New England Journal of Medicine Open access	16 Nov 2005	2,732
10	Automated detection of COVID-19 cases using deep neural networks with X-ray images Tülin Öztürk, Muhammed Talo, Eylul Azra Yildirim et al. · Computers in Biology and Medicine Open access	28 Apr 2020	2,702
11	The enhanced permeability and retention (EPR) effect in tumor vasculature: the key role of tumor-selective macromolecular drug targeting Hiroshi Maeda · Advances in Enzyme Regulation	May 2001	2,494
12	Guidelines and definitions for research on epithelial–mesenchymal transition Jing Lan Yang et al. · Nature Reviews Molecular Cell Biology ReviewOpen access	16 Apr 2020	2,379
13	Cyclodextrin Drug Carrier Systems Kaneto Uekama, Fumitoshi Hirayama, Tetsumi Irie · Chemical Reviews Review	9 Jun 1998	2,137
14	Minamata Disease: Methylmercury Poisoning in Japan Caused by Environmental Pollution Masazumi Harada · Critical Reviews in Toxicology	1995	2,076
15	Structural Basis of the Drug-binding Specificity of Human Serum Albumin Jamie Ghuman, Patricia A. Zunszain, I. Petitpas et al. · Journal of Molecular Biology	27 Aug 2005	1,939
16	The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2019) Satoshi Umemura et al. · Hypertension Research Open access	2 Aug 2019	1,903
17	Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice Duško llić, Yasuhide Furuta, S. Kanazawa et al. · Nature	Oct 1995	1,853
18	Exploiting the enhanced permeability and retention effect for tumor targeting Arun K. Iyer, Khaled F. Greish, Jun Qun Fang et al. · Drug Discovery Today	26 Aug 2006	1,845
19	JNdi-1: a neodymium isotopic reference in consistency with LaJolla neodymium Tsuyoshi Tanaka, Shigeko TOGASHI, Hikari Kamioka et al. · Chemical Geology	Aug 2000	1,806
20	The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene Hisahiro Yoshida, Shinichi Hayashi, Takahiro Kunisada et al. · Nature	May 1990	1,803
21	Report of the Committee on the Classification and Diagnostic Criteria of Diabetes Mellitus Yutaka Seino, Kishio Nanjo, Naoko Tajima et al. · Journal of Diabetes Investigation Open access	Oct 2010	1,778
22	CXCL9, CXCL10, CXCL11/CXCR3 axis for immune activation – A target for novel cancer therapy Ryuma Tokunaga, Wu Zhang, Madiha Naseem et al. · Cancer Treatment Reviews Open access	26 Nov 2017	1,718
23	Transient left ventricular apical ballooning without coronary artery stenosis: a novel heart syndrome mimicking acute myocardial infarction Kazufumi Tsuchihashi, Kenji Ueshima, Tatsuro Uchida et al. · Journal of the American College of Cardiology Open access	Jul 2001	1,662
24	Hepatic stellate cells as key target in liver fibrosis Takaaki Higashi, Scott L. Friedman, Yujin Hoshida · Advanced Drug Delivery Reviews ReviewOpen access	12 May 2017	1,509
25	Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data from randomised trials Peter Malcolm Rothwell, F.G.R. Fowkes, J. J. F. Belch et al. · The Lancet	7 Dec 2010	1,508
26	Identification and Molecular Characterization of Fractalkine Receptor CX3CR1, which Mediates Both Leukocyte Migration and Adhesion Toshio Imai, Kunio Hieshima, Christopher A. Haskell et al. · Cell Open access	Nov 1997	1,492
27	ER Stress Triggers Apoptosis by Activating BH3-Only Protein Bim Hamsa Puthalakath, Lorraine Ann O’Reilly, Priscilla Gunn et al. · Cell Open access	Jun 2007	1,445
28	SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion Petra Mlčochová et al. · Nature Open access261 authors	6 Sep 2021	1,429
29	Brain natriuretic peptide as a novel cardiac hormone in humans. Evidence for an exquisite dual natriuretic peptide system, atrial natriuretic peptide and brain natriuretic peptide. Masashi Mukoyama, Kazuwa Nakao, Kiminori Hosoda et al. · Journal of Clinical Investigation Open access	Apr 1991	1,363
30	PPARγ Mediates High-Fat Diet–Induced Adipocyte Hypertrophy and Insulin Resistance Naoto Kubota et al. · Molecular Cell Open access	Oct 1999	1,359
31	Localization and mechanism of secretion of B-type natriuretic peptide in comparison with those of A-type natriuretic peptide in normal subjects and patients with heart failure. Hirofumi Yasue, Michihiro Yoshimura, Hayakazu Sumida et al. · Circulation	Jul 1994	1,346
32	Insights into Land Plant Evolution Garnered from the Marchantia polymorpha Genome John L. Bowman et al. · Cell Open access113 authors	Oct 2017	1,314
33	Intertumoral Heterogeneity within Medulloblastoma Subgroups Florence M.G. Cavalli et al. · Cancer Cell Open access	Jun 2017	1,290
34	Establishment of a Pancreatic β Cell Line That Retains Glucose-Inducible Insulin Secretion: Special Reference to Expression of Glucose Transporter Isoforms* Jun‐ichi Miyazaki, Kimi Araki, Eiji Yamato et al. · Endocrinology	Jul 1990	1,285
35	Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene Eiichi Araki, Myra A. Lipes, Mary‐Elizabeth Patti et al. · Nature	Nov 1994	1,263
36	Crack classification in concrete based on acoustic emission Kentaro Ohno, Masayasu Ohtsu · Construction and Building Materials	10 Jun 2010	1,254
37	Cohesin mediates transcriptional insulation by CCCTC-binding factor Kerstin S. Wendt, Keisuke Yoshida, Takehiko Itoh et al. · Nature	30 Jan 2008	1,248
38	A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection Hiroshi I. Suzuki et al. · Nature	Mar 1997	1,229
39	Culture specific and cross-culturally generalizable implicit leadership theories Deanne N. Den Hartog et al. · The Leadership Quarterly Open access144 authors	1999	1,212
40	CD44 Variant Regulates Redox Status in Cancer Cells by Stabilizing the xCT Subunit of System xc− and Thereby Promotes Tumor Growth Takatsugu Ishimoto et al. · Cancer Cell Open access	Mar 2011	1,206
41	Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts infectivity and fusogenicity Bo Meng et al. · Nature Open access222 authors	Feb 2022	1,189
42	Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells Keisuke Ito, Atsushi Hirao, Fumio Arai et al. · Nature	Oct 2004	1,173
43	Usefulness of diffusion-weighted MRI with echo-planar technique in the evaluation of cellularity in gliomas Takeshi Sugahara, Yukunori Korogi, Masato Kochi et al. · Journal of Magnetic Resonance Imaging	1999	1,170
44	Rapidly Solidified Powder Metallurgy Mg97Zn1Y2Alloys with Excellent Tensile Yield Strength above 600 MPa Yoshihito Kawamura, Kentaro Hayashi, Akihisa Inoue et al. · MATERIALS TRANSACTIONS Open access	2001	1,149
45	Mapping the human genetic architecture of COVID-19 COVID-19 Host Genetics Initiative et al. · Nature Open access3,896 authors	8 Jul 2021	1,130
46	Unstable expansion of CAG repeat in hereditary dentatorubral–pallidoluysian atrophy (DRPLA) Reiji Koide, Takeshi Ikeuchi, Osamu Onodera et al. · Nature Genetics	1994	1,123
47	Fusobacterium nucleatum in colorectal carcinoma tissue and patient prognosis Kosuke Mima et al. · Gut Open access	26 Aug 2015	1,106
48	Genome sequence of the ultrasmall unicellular red alga Cyanidioschyzon merolae 10D Motomichi Matsuzaki et al. · Nature Open access	Apr 2004	1,100
49	Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1 Hiroyuki Tamemoto, Takashi Kadowaki, Kazuyuki Tobe et al. · Nature	Nov 1994	1,095
50	Explanation of machine learning models using shapley additive explanation and application for real data in hospital Yasunobu Nohara, Koutarou Matsumoto, Hidehisa Soejima et al. · Computer Methods and Programs in Biomedicine Open access	10 Dec 2021	1,073

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.