| 1 |
The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2019)
Satoshi Umemura et al. · Hypertension Research
Open access |
2 Aug 2019 |
1,903 |
| 2 |
Association of Hypoadiponectinemia With Coronary Artery Disease in Men
Masahiro Kumada, Shinji Kihara, Satoru Sumitsuji et al. · Arteriosclerosis Thrombosis and Vascular Biology
|
2003 |
1,431 |
| 3 |
Adjuvant chemotherapy of S-1 versus gemcitabine for resected pancreatic cancer: a phase 3, open-label, randomised, non-inferiority trial (JASPAC 01)
Katsuhiko Uesaka, Narikazu Boku, Akira Fukutomi et al. · The Lancet
|
3 Jun 2016 |
1,145 |
| 4 |
Increased oxidative stress in obesity: Implications for metabolic syndrome, diabetes, hypertension, dyslipidemia, atherosclerosis, and cancer
Morihiro Matsuda, Iichiro Shimomura · Obesity Research & Clinical Practice
|
14 Jun 2013 |
653 |
| 5 |
ITPKC functional polymorphism associated with Kawasaki disease susceptibility and formation of coronary artery aneurysms
Yoshihiro Onouchi et al. · Nature Genetics
Open access |
16 Dec 2007 |
525 |
| 6 |
New Serum Indicator of Interstitial Pneumonitis Activity
Kohno Nobuoki, Seishi Kyoizumi, Awaya Yukikazu et al. · CHEST Journal
|
Jul 1989 |
491 |
| 7 |
Common Defects of ABCG2, a High-Capacity Urate Exporter, Cause Gout: A Function-Based Genetic Analysis in a Japanese Population
Hirotaka Matsuo et al. · Science Translational Medicine
|
4 Nov 2009 |
442 |
| 8 |
Clinicopathological features of adult-onset neuronal intranuclear inclusion disease
Jun Sone et al. · Brain
Open access |
25 Oct 2016 |
421 |
| 9 |
Mutations in Glucose Transporter 9 Gene SLC2A9 Cause Renal Hypouricemia
Hirotaka Matsuo, Toshinori Chiba, Shushi Nagamori et al. · The American Journal of Human Genetics
Open access |
21 Nov 2008 |
392 |
| 10 |
Association of Adiponectin Mutation With Type 2 Diabetes
Hidehiko Kondo, Iichiro Shimomura, Yuko Matsukawa et al. · Diabetes
Open access |
Jul 2002 |
387 |
| 11 |
Pretreatment neutrophil count as an independent prognostic factor in advanced non-small-cell lung cancer: An analysis of Japan Multinational Trial Organisation LC00-03
Satoshi Teramukai, Toshiyuki Kitano, Yusuke Kishida et al. · European Journal of Cancer
Open access |
22 Feb 2009 |
345 |
| 12 |
Hepatoid adenocarcinomas of the stomach: An analysis of seven cases
Hiroshi Ishikura, Koji Kirimoto, Mikihiro Shamoto et al. · Cancer
Open access |
Jul 1986 |
291 |
| 13 |
Systemic IgG4-related lymphadenopathy: a clinical and pathologic comparison to multicentric Castleman's disease
Yasuharu Sato, Masaru Kojima, Katsuyoshi Takata et al. · Modern Pathology
Open access |
6 Mar 2009 |
283 |
| 14 |
EHRA expert consensus statement on arrhythmic mitral valve prolapse and mitral annular disjunction complex in collaboration with the ESC Council on valvular heart disease and the European Association of Cardiovascular Imaging endorsed cby the Heart Rhythm Society, by the Asia Pacific Heart Rhythm Society, and by the Latin American Heart Rhythm Society
Avi Sabbag et al. · EP Europace
Open access |
11 Aug 2022 |
260 |
| 15 |
Nivolumab Versus Gemcitabine or Pegylated Liposomal Doxorubicin for Patients With Platinum-Resistant Ovarian Cancer: Open-Label, Randomized Trial in Japan (NINJA)
Junzo Hamanishi et al. · Journal of Clinical Oncology
Open access |
2 Sep 2021 |
212 |
| 16 |
The Japanese Society of Hypertension Guidelines for Self-monitoring of Blood Pressure at Home (Second Edition)
Yutaka Imai, Kazuomi Kario, Kazuyuki Shimada et al. · Hypertension Research
Open access |
Aug 2012 |
204 |
| 17 |
Adiponectin I164T mutation is associated with the metabolic syndrome and coronary artery disease
Koji Ohashi et al. · Journal of the American College of Cardiology
Open access |
Apr 2004 |
203 |
| 18 |
Recurrence of meningiomas
Fumiyuki Yamasaki, Hiroyuki Yoshioka, Seiji Hama et al. · Cancer
Open access |
Sep 2000 |
203 |
| 19 |
JCS/JHRS 2019 Guideline on Non-Pharmacotherapy of Cardiac Arrhythmias
Akihiko Nogami et al. · Circulation Journal
Open access |
31 May 2021 |
200 |
| 20 |
Gasdermin C Is Upregulated by Inactivation of Transforming Growth Factor β Receptor Type II in the Presence of Mutated Apc, Promoting Colorectal Cancer Proliferation
Masashi Miguchi, Takao Hinoi, Manabu Shimomura et al. · PLoS ONE
Open access |
11 Nov 2016 |
198 |
| 21 |
Roles of adiponectin and oxidative stress in obesity-associated metabolic and cardiovascular diseases
Morihiro Matsuda, Iichiro Shimomura · Reviews in Endocrine and Metabolic Disorders
|
12 Sep 2013 |
196 |
| 22 |
Breast Cancer DNA Methylation Profiles in Cancer Cells and Tumor Stroma: Association with HER-2/neu Status in Primary Breast Cancer
Heidi Fiegl, Simone Millinger, Georg Goebel et al. · Cancer Research
|
2006 |
171 |
| 23 |
Adipose‐derived mesenchymal stem cells and regenerative medicine
Masamitsu Konno, Atsushi Hamabe, Shinichiro Hasegawa et al. · Development Growth & Differentiation
|
3 Mar 2013 |
166 |
| 24 |
Phase III randomised controlled trial of neoadjuvant chemotherapy plus radical surgery vs radical surgery alone for stages IB2, IIA2, and IIB cervical cancer: a Japan Clinical Oncology Group trial (JCOG 0102)
Noriyuki Katsumata, Hiroyuki Yoshikawa, Hiroaki Kobayashi et al. · British Journal of Cancer
Open access |
May 2013 |
149 |
| 25 |
Risk estimation model for nonalcoholic fatty liver disease in the Japanese using multiple genetic markers
Takahisa Kawaguchi et al. · PLoS ONE
Open access |
31 Jan 2018 |
148 |
| 26 |
Expression of survivin in astrocytic tumors
Yoshinori Kajiwara, Fumiyuki Yamasaki, Seiji Hama et al. · Cancer
|
3 Feb 2003 |
148 |
| 27 |
Report of the Working Group for Dietary Salt Reduction of the Japanese Society of Hypertension: (2) Assessment of Salt Intake in the Management of Hypertension
Yuhei Kawano, Takuya Tsuchihashi, Hideo Matsuura et al. · Hypertension Research
Open access |
2007 |
144 |
| 28 |
Two decades of annual medical examinations in Japanese obese children: Do obese children grow into obese adults?
Kazuaki Kotani, M. Nishida, Shizuya Yamashita et al. · International Journal of Obesity
|
Oct 1997 |
143 |
| 29 |
Decreased levels of whole blood glial cell line-derived neurotrophic factor (GDNF) in remitted patients with mood disorders
Minoru Takebayashi, Kazue Hisaoka, Akira Nishida et al. · The International Journal of Neuropsychopharmacology
|
28 Sep 2005 |
135 |
| 30 |
Esophageal body and lower esophageal sphincter function in healthy premature infants
Taher Imad Omari, Kazunori Miki, Robert J. Fraser et al. · Gastroenterology
Open access |
Dec 1995 |
134 |
| 31 |
Antidepressant drug treatments induce glial cell line‐derived neurotrophic factor (GDNF) synthesis and release in rat C6 glioblastoma cells
Kazue Hisaoka, Akira Nishida, Tetsuzo Koda et al. · Journal of Neurochemistry
|
Oct 2001 |
133 |
| 32 |
A prospective multicenter study on self-expandable metallic stents as a bridge to surgery for malignant colorectal obstruction in Japan: efficacy and safety in 312 patients
Shuji Saito, Shuntaro Yoshida, Hiroyuki Isayama et al. · Surgical Endoscopy
|
18 Dec 2015 |
130 |
| 33 |
Bmi-1 is useful as a novel molecular marker for predicting progression of myelodysplastic syndrome and patient prognosis
Keichiro Mihara, Moniruddin Chowdhury, Nanae Nakaju et al. · Blood
|
14 Sep 2005 |
130 |
| 34 |
Long-term survival and prognostic factors in the surgical treatment for intrahepatic cholangiocarcinoma
Yoshikazu Morimoto, Yasuhiro Tanaka, Toshinori Ito et al. · Journal of Hepato-Biliary-Pancreatic Surgery
|
Dec 2003 |
128 |
| 35 |
A phase II trial evaluating the efficacy and safety of perioperative pirfenidone for prevention of acute exacerbation of idiopathic pulmonary fibrosis in lung cancer patients undergoing pulmonary resection: West Japan Oncology Group 6711 L (PEOPLE Study)
West Japan Oncology Group et al. · Respiratory Research
Open access |
22 Jul 2016 |
127 |
| 36 |
New and emerging techniques for endoscopic treatment of Zenker's diverticulum: State‐of‐the‐art review
Sauid Ishaq, Haleema Sultan, Keith Siau et al. · Digestive Endoscopy
Open access |
9 Feb 2018 |
123 |
| 37 |
Chylomicron remnants are increased in the postprandial state in CD36 deficiency
Daisaku Masuda, Ken‐ichi Hirano, Hiroyuki Oku et al. · Journal of Lipid Research
Open access |
27 Aug 2008 |
122 |
| 38 |
Mechanism for reduction of serum folate by antiepileptic drugs during prolonged therapy
Takamasa Kishi, Naoto Fujita, Takaatsu Eguchi et al. · Journal of the Neurological Sciences
|
1997 |
117 |
| 39 |
Differentiated thyroid carcinoma with airway invasion: Indication for tracheal resection based on the extent of cancer invasion
Toshirou Nishida, Kazuyasu Nakao, Masayasu Hamaji · Journal of Thoracic and Cardiovascular Surgery
Open access |
Jul 1997 |
114 |
| 40 |
Human Catalase Gene is Regulated by Peroxisome Proliferator Activated Receptor-gamma through a Response Element Distinct from That of Mouse
Yosuke Okuno, Morihiro Matsuda, Yugo Miyata et al. · Endocrine Journal
Open access |
2010 |
113 |
| 41 |
Outcome of long standing solitary thyroid nodules
Kanji Kuma, Fumio Matsuzuka, Akira Kobayashi et al. · World Journal of Surgery
|
Jul 1992 |
112 |
| 42 |
Second nation-wide study of atherosclerosis in infants, children and young adults in Japan
Masami Imakita, Chikao Yutani, Jack P. Strong et al. · Atherosclerosis
|
Apr 2001 |
110 |
| 43 |
Existential concerns of terminally ill cancer patients receiving specialized palliative care in Japan
Tatsuya Morita, Masako Kawa, Yoshifumi Honke et al. · Supportive Care in Cancer
|
30 Jan 2004 |
109 |
| 44 |
Comparison of Human Serum with Fetal Bovine Serum for Expansion and Differentiation of Human Synovial MSC: Potential Feasibility for Clinical Applications
Kosuke Tateishi, Wataru Ando, Chikahisa Higuchi et al. · Cell Transplantation
Open access |
May 2008 |
108 |
| 45 |
Long-term outcomes after treatment for T1 colorectal carcinoma: a multicenter retrospective cohort study of Hiroshima GI Endoscopy Research Group
Yuzuru Tamaru, Shiro Oka, Shinji Tanaka et al. · Journal of Gastroenterology
|
13 Feb 2017 |
107 |
| 46 |
High Incidence of Meningioma among Hiroshima Atomic Bomb Survivors
Takahiro Shintani, Norihiko Hayakawa, Masaharu Hoshi et al. · Journal of Radiation Research
Open access |
1999 |
103 |
| 47 |
Thiazolidinedione derivative improves fat distribution and multiple risk factors in subjects with visceral fat accumulation—double-blind placebo-controlled trial
Tadashi Nakamura, Tohru Funahashi, Shizuya Yamashita et al. · Diabetes Research and Clinical Practice
|
Dec 2001 |
103 |
| 48 |
Underexpression of mRNA in human hepatocellular carcinoma focusing on eight loci
Moritoshi Kinoshita, Masahiko Miyata · Hepatology
Open access |
Aug 2002 |
99 |
| 49 |
Clinical tumor diameter and prognosis of patients with FIGO stage IB1 cervical cancer (JCOG0806-A)
Tomoyasu Kato et al. · Gynecologic Oncology
|
7 Feb 2015 |
99 |
| 50 |
Antidepressants Increase Glial Cell Line-Derived Neurotrophic Factor Production through Monoamine-Independent Activation of Protein Tyrosine Kinase and Extracellular Signal-Regulated Kinase in Glial Cells
Kazue Hisaoka, Minoru Takebayashi, Mami Tsuchioka et al. · Journal of Pharmacology and Experimental Therapeutics
|
9 Jan 2007 |
98 |