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Most cited papers from La Jolla Bioengineering Institute

What are the most cited papers from La Jolla Bioengineering Institute?

The most cited paper from La Jolla Bioengineering Institute is "PHENIX : a comprehensive Python-based system for macromolecular structure solution" (Paul D. Adams, Pavel V. Afonine, G. Bunkóczi et al., 2010), with 24,924 citations. Next come "A component based noise correction method (CompCor) for BOLD and perfusion based fMRI" (4,975) and "Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking" (4,812).

Showing 50 of 58 papers. Every paper with more than 810 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 PHENIX : a comprehensive Python-based system for macromolecular structure solution Paul D. Adams, Pavel V. Afonine, G. Bunkóczi et al. · Acta Crystallographica Section D Biological Crystallography Open access 21 Jan 2010 24,924
2 A component based noise correction method (CompCor) for BOLD and perfusion based fMRI Yashar Behzadi, Khaled Restom, Joy Liau et al. · NeuroImage Open access 4 May 2007 4,975
3 Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking Mingxun Wang et al. · Nature Biotechnology Open access127 authors Aug 2016 4,812
4 Integration of biological networks and gene expression data using Cytoscape Melissa Cline et al. · Nature Protocols Open access 27 Sep 2007 2,601
5 Effects of Disturbed Flow on Vascular Endothelium: Pathophysiological Basis and Clinical Perspectives Jeng‐Jiann Chiu, Shu Chien · Physiological Reviews ReviewOpen access 2011 2,273
6 Macrophage Polarization: Different Gene Signatures in M1(LPS+) vs. Classically and M2(LPS–) vs. Alternatively Activated Macrophages Marco Orecchioni, Yanal Ghosheh, Akula Bala Pramod et al. · Frontiers in Immunology Open access 24 May 2019 2,138
7 Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox v2.0 Jan Schellenberger, Richard A. Que, Ronan M. T. Fleming et al. · Nature Protocols Open access 4 Aug 2011 1,925
8 A protocol for generating a high-quality genome-scale metabolic reconstruction Ines Thiele, Bernhard Ørn Palsson · Nature Protocols Open access 2010 1,918
9 Neuromorphic Silicon Neuron Circuits Giacomo Indiveri, B. Linares-Barranco, Tara Julia Hamilton et al. · Frontiers in Neuroscience Open access 2011 1,844
10 Immunity and Inflammation in Atherosclerosis Dennis Wolf, Klaus Ley · Circulation Research Open access 17 Jan 2019 1,768
11 ClassyFire: automated chemical classification with a comprehensive, computable taxonomy Yannick Djoumbou-Feunang, Roman Eisner, Craig Knox et al. · Journal of Cheminformatics Open access 4 Nov 2016 1,655
12 COBRApy: COnstraints-Based Reconstruction and Analysis for Python Ali Ebrahim, Joshua A. Lerman, Bernhard Ørn Palsson et al. · BMC Systems Biology Open access 8 Aug 2013 1,565
13 Network‐based classification of breast cancer metastasis Han‐Yu Chuang, Eunjung Lee, Yu‐Tsueng Liu et al. · Molecular Systems Biology Open access 16 Oct 2007 1,458
14 electronic Ligand Builder and Optimization Workbench ( eLBOW ): a tool for ligand coordinate and restraint generation Nigel W. Moriarty, Ralf W. Grosse‐Kunstleve, Paul D. Adams · Acta Crystallographica Section D Biological Crystallography Open access 15 Sep 2009 1,456
15 A genome‐scale metabolic reconstruction for Escherichia coli K‐12 MG1655 that accounts for 1260 ORFs and thermodynamic information Adam M. Feist, Christopher S. Henry, Jennifer L. Reed et al. · Molecular Systems Biology Open access 26 Jun 2007 1,438
16 LMSD: LIPID MAPS structure database Manish Sud, Eoin Fahy, David Cotter et al. · Nucleic Acids Research Open access 13 Nov 2006 1,421
17 Genome-wide analysis of mammalian promoter architecture and evolution Piero Carninci et al. · Nature Genetics 27 Apr 2006 1,421
18 Technology Roadmap for Flexible Sensors Yifei Luo et al. · ACS Nano Open access142 authors 9 Mar 2023 1,368
19 Deciphering cell–cell interactions and communication from gene expression Erick Armingol, Adam Officer, Olivier Harismendy et al. · Nature Reviews Genetics ReviewOpen access 9 Nov 2020 1,367
20 Somatic coding mutations in human induced pluripotent stem cells Athurva Gore et al. · Nature Open access Mar 2011 1,274
21 In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration Keiichiro Suzuki et al. · Nature Open access 15 Nov 2016 1,216
22 Human Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice Gil Sharon et al. · Cell Open access May 2019 1,214
23 Tensile properties of the human femur-anterior cruciate ligament-tibia complex Savio L‐Y. Woo, J. Marcus Hollis, Douglas J. Adams et al. · The American Journal of Sports Medicine May 1991 1,203
24 Turning a surface superrepellent even to completely wetting liquids Tingyi “Leo” Liu, Chang‐Jin Kim · Science Open access 28 Nov 2014 1,154
25 Antimicrobials from human skin commensal bacteria protect against Staphylococcus aureus and are deficient in atopic dermatitis Teruaki Nakatsuji et al. · Science Translational Medicine Open access 22 Feb 2017 1,120
26 Preparation of Hydrogel Substrates with Tunable Mechanical Properties Justin R. Tse, Adam Jeffrey Engler · Current Protocols in Cell Biology Jun 2010 1,110
27 A comprehensive genome‐scale reconstruction of Escherichia coli metabolism—2011 Jeffrey D. Orth, Tom M Conrad, Jessica Na et al. · Molecular Systems Biology Open access 11 Oct 2011 1,086
28 Fractal design concepts for stretchable electronics Jonathan A. Fan, Woon‐Hong Yeo, Yewang Su et al. · Nature Communications Open access 7 Feb 2014 1,085
29 Genome-scale models of microbial cells: evaluating the consequences of constraints Nathan D. Price, Jennifer L. Reed, Bernhard Ørn Palsson · Nature Reviews Microbiology Review 20 Oct 2004 1,052
30 An expanded genome-scale model of Escherichia coli K-12 (iJR904 GSM/GPR) Jennifer L. Reed, Thuy D. Vo, Christophe H. Schilling et al. · Genome biology Open access 28 Aug 2003 1,032
31 In situ sprayed bioresponsive immunotherapeutic gel for post-surgical cancer treatment Qian Chen, Chao Wang, Xudong Zhang et al. · Nature Nanotechnology 4 Dec 2018 1,028
32 Matrix stiffness drives epithelial–mesenchymal transition and tumour metastasis through a TWIST1–G3BP2 mechanotransduction pathway Spencer C. Wei, Laurent Fattet, Jeff H. Tsai et al. · Nature Cell Biology Open access 20 Apr 2015 1,004
33 The Phenix software for automated determination of macromolecular structures Paul D. Adams, Pavel V. Afonine, G. Bunkóczi et al. · Methods Open access 2 Aug 2011 994
34 Conformable amplified lead zirconate titanate sensors with enhanced piezoelectric response for cutaneous pressure monitoring Canan Dağdeviren, Yewang Su, Pauline Joe et al. · Nature Communications Open access 5 Aug 2014 986
35 Skin microbiota: a source of disease or defence? Anna L. Cogen, Victor Nizet, Richard L. Gallo · British Journal of Dermatology Open access 11 Feb 2008 985
36 Materials as stem cell regulators William L. Murphy, Todd C. McDevitt, Adam Jeffrey Engler · Nature Materials Open access 21 May 2014 967
37 In silico predictions of Escherichia coli metabolic capabilities are consistent with experimental data Jeremy S. Edwards, Rafael U. Ibarra, Bernhard Ørn Palsson · Nature Biotechnology Feb 2001 961
38 Interplay of matrix stiffness and protein tethering in stem cell differentiation Jessica H. Wen, Ludovic G. Vincent, Alexander Fuhrmann et al. · Nature Materials Open access 8 Aug 2014 959
39 Precise phylogenetic analysis of microbial isolates and genomes from metagenomes using PhyloPhlAn 3.0 Francesco Asnicar, Andrew Maltez Thomas, Francesco Beghini et al. · Nature Communications Open access 19 May 2020 944
40 Chronic Venous Disease John J. Bergan, Geert W. Schmid‐Schönbein, Philip D Coleridge Smith et al. · New England Journal of Medicine 2 Aug 2006 937
41 Update on LIPID MAPS classification, nomenclature, and shorthand notation for MS-derived lipid structures Gerhard Liebisch, Eoin Fahy, Junken Aoki et al. · Journal of Lipid Research Open access 19 Oct 2020 922
42 High-throughput sequencing of the transcriptome and chromatin accessibility in the same cell Song Chen, Blue B. Lake, Kun Zhang · Nature Biotechnology Open access 14 Oct 2019 918
43 Mechanotransduction and endothelial cell homeostasis: the wisdom of the cell Shu Chien · American Journal of Physiology-Heart and Circulatory Physiology 13 Nov 2006 915
44 Monitoring of the central blood pressure waveform via a conformal ultrasonic device Chonghe Wang et al. · Nature Biomedical Engineering Open access 4 Sep 2018 902
45 Constraint-based models predict metabolic and associated cellular functions Aarash Bordbar, Jonathan M. Monk, Zachary A. King et al. · Nature Reviews Genetics Review 16 Jan 2014 890
46 Escherichia coli K-12 undergoes adaptive evolution to achieve in silico predicted optimal growth Rafael U. Ibarra, Jeremy S. Edwards, Bernhard Ørn Palsson · Nature Nov 2002 885
47 Deterministically patterned biomimetic human iPSC-derived hepatic model via rapid 3D bioprinting Xuanyi Ma, Xin Qu, Wei Zhong Zhu et al. · Proceedings of the National Academy of Sciences Open access 8 Feb 2016 884
48 Applications of genome‐scale metabolic reconstructions Matthew Oberhardt, Bernhard Ørn Palsson, Jason A. Papin · Molecular Systems Biology Open access 3 Nov 2009 871
49 Differential network biology Trey Ideker, Nevan J. Krogan · Molecular Systems Biology Open access 17 Jan 2012 853
50 Omic data from evolved E. coli are consistent with computed optimal growth from genome‐scale models Nathan E. Lewis, Kim K. Hixson, Tom M Conrad et al. · Molecular Systems Biology Open access 27 Jul 2010 846

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.