| 1 |
Identification of the von Hippel-Lindau Disease Tumor Suppressor Gene
Farida Latif et al. · Science
|
28 May 1993 |
3,023 |
| 2 |
22q11.21 Deletion Syndromes: A Review of Proximal, Central, and Distal Deletions and Their Associated Features
Rachel D. Burnside · Cytogenetic and Genome Research
Open access |
2015 |
1,968 |
| 3 |
Some Forms of the Strain Energy Function for Rubber
Oon Hock Yeoh · Rubber Chemistry and Technology
|
Nov 1993 |
1,629 |
| 4 |
Correlates of protection against symptomatic and asymptomatic SARS-CoV-2 infection
Shuo Feng et al. · Nature Medicine
Open access |
29 Sep 2021 |
1,247 |
| 5 |
DNA Deaminating Ability and Genotoxicity of Nitric Oxide and its Progenitors
David A. Wink, Kazimierz S. Kasprzak, Chris M. Maragos et al. · Science
|
15 Nov 1991 |
1,246 |
| 6 |
Long-term proliferation of mouse primordial germ cells in culture
James L. Resnick, Lynn S. Bixler, Linzhao Cheng et al. · Nature
|
Oct 1992 |
874 |
| 7 |
Hemophilia B Gene Therapy with a High-Specific-Activity Factor IX Variant
Lindsey A. George et al. · New England Journal of Medicine
Open access |
6 Dec 2017 |
774 |
| 8 |
Characterization of Elastic Properties of Carbon-Black-Filled Rubber Vulcanizates
Oon Hock Yeoh · Rubber Chemistry and Technology
|
Nov 1990 |
740 |
| 9 |
T cell and antibody responses induced by a single dose of ChAdOx1 nCoV-19 (AZD1222) vaccine in a phase 1/2 clinical trial
Katie Ewer et al. · Nature Medicine
Open access284 authors |
17 Dec 2020 |
646 |
| 10 |
Phosphorylation and activation of the Jak-3 Janus kinase in response to interleukin-2
James A. Johnston, Masaru Kawamura, Robert Arthur Kirken et al. · Nature
Open access |
Jul 1994 |
600 |
| 11 |
A New Equation for Calculation of Low-Density Lipoprotein Cholesterol in Patients With Normolipidemia and/or Hypertriglyceridemia
Maureen L. Sampson, Clarence Ling, Qian Sun et al. · JAMA Cardiology
Open access |
26 Feb 2020 |
585 |
| 12 |
The Use and Interpretation of CommercialAPCGene Testing for Familial Adenomatous Polyposis
Francis M. Giardiello, Jill D. Brensinger, Gloria M. Petersen et al. · New England Journal of Medicine
|
20 Mar 1997 |
498 |
| 13 |
THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein‐coupled receptors
S P H Alexander et al. · British Journal of Pharmacology
Open access155 authors |
16 Sep 2021 |
489 |
| 14 |
Increases in CD4 T Lymphocytes with Intermittent Courses of Interleukin-2 in Patients with Human Immunodeficiency Virus Infection — A Preliminary Study
Joseph A. Kovacs, Michael Baseler, Robin J. Dewar et al. · New England Journal of Medicine
Open access |
2 Mar 1995 |
430 |
| 15 |
GlycA: A Composite Nuclear Magnetic Resonance Biomarker of Systemic Inflammation
James Dorian Otvos, IRINA Y. SHALAUROVA, Justyna Wolak-Dinsmore et al. · Clinical Chemistry
|
17 Mar 2015 |
419 |
| 16 |
The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors
S P H Alexander et al. · British Journal of Pharmacology
Open access166 authors |
Oct 2023 |
393 |
| 17 |
Chronic Active Hepatitis and Associated Liver Tumors in Mice Caused by a Presistent Bacterial Infection With a Novel Helicobacter Species
Jerrold Michael Ward, Jane G. Fox, Miriam R. Anver et al. · JNCI Journal of the National Cancer Institute
|
17 Aug 1994 |
390 |
| 18 |
Indirect methods for reference interval determination – review and recommendations
Graham R.D. Jones, Rainer Haeckel, Tze Ping Loh et al. · Clinical Chemistry and Laboratory Medicine (CCLM)
|
19 Apr 2018 |
353 |
| 19 |
Phase 1/2 trial of SARS-CoV-2 vaccine ChAdOx1 nCoV-19 with a booster dose induces multifunctional antibody responses
Jordan R. Barrett et al. · Nature Medicine
Open access303 authors |
17 Dec 2020 |
344 |
| 20 |
Cytogenetics of papillary renal cell tumors
Gyula Kovács, LASZLO FÜZESI, Angela R. Emanuel et al. · Genes Chromosomes and Cancer
|
Jul 1991 |
329 |
| 21 |
Characterization of infectious aerosols in health care facilities: An aid to effective engineering controls and preventive strategies
Eugene C. Cole, Carl E. Cook · American Journal of Infection Control
Open access |
Aug 1998 |
324 |
| 22 |
Hereditary Papillary Renal Cell Carcinoma
Berton Zbar, Kálmán Tory, María José Beato Merino et al. · The Journal of Urology
|
Mar 1994 |
317 |
| 23 |
GlycA, a novel biomarker of systemic inflammation and cardiovascular disease risk
Margery A. Connelly, James Dorian Otvos, IRINA Y. SHALAUROVA et al. · Journal of Translational Medicine
Open access |
27 Oct 2017 |
302 |
| 24 |
Treatment of Refractory Disseminated Nontuberculous Mycobacterial Infection With Interferon Gamma: A Preliminary Report
Steven M. Holland, Eli M. Eisenstein, Douglas Byron Kuhns et al. · New England Journal of Medicine
|
12 May 1994 |
302 |
| 25 |
Predictive validity of biochemical biomarkers in knee osteoarthritis: data from the FNIH OA Biomarkers Consortium
Virginia B. Kraus, Jamie E. Collins, David Hargrove et al. · Annals of the Rheumatic Diseases
Open access |
13 Jun 2016 |
295 |
| 26 |
Association of SARS-CoV-2 Seropositive Antibody Test With Risk of Future Infection
Raymond A. Harvey, Jeremy A. Rassen, Carly A. Kabelac et al. · JAMA Internal Medicine
Open access |
24 Feb 2021 |
288 |
| 27 |
Establishing Reference Intervals for Clinical Laboratory Test Results
Alex Katayev, Claudiu Balciza, David W. Seccombe · American Journal of Clinical Pathology
Open access |
21 Jan 2010 |
283 |
| 28 |
Let-7 family of microRNA is required for maturation and adult-like metabolism in stem cell-derived cardiomyocytes
Kavitha T. Kuppusamy, Daniel C. Jones, Henrik Sperber et al. · Proceedings of the National Academy of Sciences
Open access |
11 May 2015 |
277 |
| 29 |
Comparison of APTIMA Trichomonas vaginalis transcription-mediated amplification to wet mount microscopy, culture, and polymerase chain reaction for diagnosis of trichomoniasis in men and women
Melinda B. Nye, Jane R. Schwebke, Barbara A. Body · American Journal of Obstetrics and Gynecology
|
29 Jan 2009 |
270 |
| 30 |
Safety and efficacy of once-weekly efruxifermin versus placebo in non-alcoholic steatohepatitis (HARMONY): a multicentre, randomised, double-blind, placebo-controlled, phase 2b trial
Stephen A. Harrison, Juan P. Frías, Guy W. Neff et al. · The Lancet. Gastroenterology & hepatology
|
3 Oct 2023 |
266 |
| 31 |
Leukaemia hijacks a neural mechanism to invade the central nervous system
Hisayuki Yao, Trevor T. Price, Gaia Cantelli et al. · Nature
Open access |
17 Jul 2018 |
263 |
| 32 |
Microdeletion/microduplication of proximal 15q11.2 between BP1 and BP2: a susceptibility region for neurological dysfunction including developmental and language delay
Rachel D. Burnside, Romela M. Pasion, Fady M. Mikhail et al. · Human Genetics
Open access |
26 Feb 2011 |
261 |
| 33 |
Meiotic initiation by the mos protein in Xenopus
Nelson S. Yew, M Mellini, Coleen K. Martinez et al. · Nature
|
Feb 1992 |
255 |
| 34 |
Assessment of 2q23.1 Microdeletion Syndrome Implicates MBD5 as a Single Causal Locus of Intellectual Disability, Epilepsy, and Autism Spectrum Disorder
Michael E. Talkowski et al. · The American Journal of Human Genetics
Open access |
Oct 2011 |
250 |
| 35 |
Comparison of Commercially Available and Laboratory-Developed Assays for In Vitro Detection of SARS-CoV-2 in Clinical Laboratories
Joshua A. Lieberman, Gregory Pepper, Samia N. Naccache et al. · Journal of Clinical Microbiology
Open access |
30 Apr 2020 |
248 |
| 36 |
Recommendations for the Generation, Quantification, Storage, and Handling of Peptides Used for Mass Spectrometry–Based Assays
Andrew N. Hoofnagle et al. · Clinical Chemistry
Open access |
30 Dec 2015 |
238 |
| 37 |
Liquid chromatography–tandem mass spectrometry for clinical diagnostics
Stefani N. Thomas, Deborah French, Paul J. Jannetto et al. · Nature Reviews Methods Primers
ReviewOpen access |
8 Dec 2022 |
231 |
| 38 |
Technical Standards and Guidelines for Fragile X: The First of a Series of Disease-Specific Supplements to the Standards and Guidelines for Clinical Genetics Laboratories of the American College of Medical Genetics
Anne Maddalena, Carolyn Sue Richards, Matthew Jerome McGinniss et al. · Genetics in Medicine
Open access |
May 2001 |
231 |
| 39 |
Molecular modifiers reveal a mechanism of pathological crystal growth inhibition
Jihae Chung, Ignacio Granja, Michael G. Taylor et al. · Nature
|
Aug 2016 |
223 |
| 40 |
Recommendations for Improved Standardization of Immunohistochemistry
Neal S. Goldstein, Stephen M. Hewitt, Clive R. Taylor et al. · Applied immunohistochemistry & molecular morphology
|
23 May 2007 |
222 |
| 41 |
National Kidney Foundation Laboratory Engagement Working Group Recommendations for Implementing the CKD-EPI 2021 Race-Free Equations for Estimated Glomerular Filtration Rate: Practical Guidance for Clinical Laboratories
W. Greg Miller, Harvey W. Kaufman, Andrew S. Levey et al. · Clinical Chemistry
Open access |
11 Dec 2021 |
220 |
| 42 |
Hodgkin's Disease
Walter John Urba, Dan L. Longo · New England Journal of Medicine
|
5 Mar 1992 |
217 |
| 43 |
A multigene mutation classification of 468 colorectal cancers reveals a prognostic role for APC
Michael J. Schell, Mingli Yang, Jamie K. Teer et al. · Nature Communications
Open access |
15 Jun 2016 |
216 |
| 44 |
Prolonged viral suppression with anti-HIV-1 antibody therapy
Christian Gaebler et al. · Nature
Open access |
13 Apr 2022 |
213 |
| 45 |
Cloning and functional characteristics of murine large granular lymphocyte-1: a member of the Ly-49 gene family (Ly-49G2)
Llewellyn H. Mason, John R. Ortaldo, Howard A. Young et al. · The Journal of Experimental Medicine
Open access |
Aug 1995 |
208 |
| 46 |
Cutaneous angiosarcoma: a case series with prognostic correlation
Michael B Morgan, Michael Swann, Stephen C. Somach et al. · Journal of the American Academy of Dermatology
|
29 May 2004 |
207 |
| 47 |
UPD detection using homozygosity profiling with a SNP genotyping microarray
Peter R. Papenhausen, Stuart H. Schwartz, Hiba Risheg et al. · American Journal of Medical Genetics Part A
|
15 Mar 2011 |
203 |
| 48 |
Effects of Age and Serum 25-OH-Vitamin D on Serum Parathyroid Hormone Levels
André Valcour, Frank A. Blocki, Douglas M. Hawkins et al. · The Journal of Clinical Endocrinology & Metabolism
|
30 Aug 2012 |
192 |
| 49 |
Sensitivity of single-strand conformation polymorphism and heteroduplex method for mutation detection in the cystic fibrosis gene
Metka Ravnlk-Glavač, Damjan Glavač, Michael C. Dean · Human Molecular Genetics
|
1994 |
189 |
| 50 |
Phenotypic and genotypic analysis of clinical HIV-1 isolates reveals extensive protease inhibitor cross-resistance: a survey of over 6000 samples
Kurt Hertogs, Stuart Bloor, Sharon D. Kemp et al. · AIDS
|
Jun 2000 |
185 |