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Most cited papers from Linyi People's Hospital

What are the most cited papers from Linyi People's Hospital?

The most cited paper from Linyi People's Hospital is "Afatinib versus cisplatin plus gemcitabine for first-line treatment of Asian patients with advanced non-small-cell lung cancer harbouring EGFR mutations (LUX-Lung 6): an open-label, randomised phase 3 trial" (Yi-Long Lung Cancer Wu, Caicun Zhou, Chengping Hu et al., 2014), with 1,992 citations. Next come "Trial of Endovascular Therapy for Acute Ischemic Stroke with Large Infarct" (893) and "Genome-wide association study identifies susceptibility loci for polycystic ovary syndrome on chromosome 2p16.3, 2p21 and 9q33.3" (863).

Showing 50 of 60 papers. Every paper with more than 121 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Afatinib versus cisplatin plus gemcitabine for first-line treatment of Asian patients with advanced non-small-cell lung cancer harbouring EGFR mutations (LUX-Lung 6): an open-label, randomised phase 3 trial Yi-Long Lung Cancer Wu, Caicun Zhou, Chengping Hu et al. · The Lancet Oncology 14 Jan 2014 1,992
2 Trial of Endovascular Therapy for Acute Ischemic Stroke with Large Infarct Xiaochuan Huo et al. · New England Journal of Medicine 10 Feb 2023 893
3 Genome-wide association study identifies susceptibility loci for polycystic ovary syndrome on chromosome 2p16.3, 2p21 and 9q33.3 Zi‐Jiang Chen et al. · Nature Genetics 12 Dec 2010 863
4 Endovascular Thrombectomy with or without Intravenous Alteplase in Acute Stroke Pengfei Yang et al. · New England Journal of Medicine Open access 6 May 2020 850
5 Burden of 375 diseases and injuries, risk-attributable burden of 88 risk factors, and healthy life expectancy in 204 countries and territories, including 660 subnational locations, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023 Simon I Hay et al. · The Lancet Open access2,780 authors Oct 2025 762
6 Genome-wide association study identifies eight new risk loci for polycystic ovary syndrome Yongyong Shi et al. · Nature Genetics 12 Aug 2012 753
7 CRISPR/Cas9 therapeutics: progress and prospects Tianxiang Li, Yanyan Yang, Hongzhao Qi et al. · Signal Transduction and Targeted Therapy Open access 16 Jan 2023 725
8 Trial of Endovascular Treatment of Acute Basilar-Artery Occlusion Chunrong Tao et al. · New England Journal of Medicine Open access 12 Oct 2022 681
9 Endovascular treatment versus standard medical treatment for vertebrobasilar artery occlusion (BEST): an open-label, randomised controlled trial Xinfeng Liu et al. · The Lancet Neurology 143 authors 9 Dec 2019 657
10 Dietary patterns and depression risk: A meta-analysis Ye Li, Mei-Rong Lv, Yan-Jin Wei et al. · Psychiatry Research Review 11 Apr 2017 605
11 Toripalimab plus chemotherapy in treatment-naïve, advanced esophageal squamous cell carcinoma (JUPITER-06): A multi-center phase 3 trial Zixian Wang et al. · Cancer Cell Open access Mar 2022 592
12 Oral bioavailability of curcumin: problems and advancements Weidong Liu, Yingjie Zhai, Xueyuan Heng et al. · Journal of drug targeting 4 Mar 2016 567
13 Global burden of 292 causes of death in 204 countries and territories and 660 subnational locations, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023 Mohsen Naghavi et al. · The Lancet Open access2,463 authors Oct 2025 500
14 Exosomes from bone marrow mesenchymal stem cells enhance fracture healing through the promotion of osteogenesis and angiogenesis in a rat model of nonunion Lu Zhang, Guangjun Jiao, Shanwu Ren et al. · Stem Cell Research & Therapy Open access 28 Jan 2020 376
15 Global, regional, and national burden of chronic kidney disease in adults, 1990–2023, and its attributable risk factors: a systematic analysis for the Global Burden of Disease Study 2023 Patrick B Mark et al. · The Lancet Open access597 authors Nov 2025 366
16 Assessment of Endovascular Treatment for Acute Basilar Artery Occlusion via a Nationwide Prospective Registry Writing Group for the BASILAR Group et al. · JAMA Neurology Open access 21 Feb 2020 363
17 Uncontrolled hypertension increases risk of all-cause and cardiovascular disease mortality in US adults: the NHANES III Linked Mortality Study Donghao Zhou, Bo Xi, Min Zhao et al. · Scientific Reports Open access 14 Jun 2018 362
18 2020 Chinese guidelines for ultrasound malignancy risk stratification of thyroid nodules: the C-TIRADS Jianqiao Zhou et al. · Endocrine 239 authors 21 Aug 2020 348
19 Role and mechanisms of cytokines in the secondary brain injury after intracerebral hemorrhage Huimin Zhu, Zhiqiang Wang, Jixu Yu et al. · Progress in Neurobiology 25 Mar 2019 343
20 Camrelizumab Plus Carboplatin and Paclitaxel as First-Line Treatment for Advanced Squamous NSCLC (CameL-Sq): A Phase 3 Trial Shengxiang Ren et al. · Journal of Thoracic Oncology Open access 16 Dec 2021 326
21 Tenecteplase versus alteplase in acute ischaemic cerebrovascular events (TRACE-2): a phase 3, multicentre, open-label, randomised controlled, non-inferiority trial Yongjun Wang et al. · The Lancet Feb 2023 313
22 circTADA2As suppress breast cancer progression and metastasis via targeting miR-203a-3p/SOCS3 axis Jianzhen Xu, Changchun Shao, Xiaojia Wang et al. · Cell Death and Disease Open access 20 Feb 2019 311
23 Therapeutic potentials of gene silencing by RNA interference: Principles, challenges, and new strategies Yan Ping Deng, Chi Chiu Wang, Kwong Wai Choy et al. · Gene 6 Jan 2014 304
24 Sugar-sweetened beverages and risk of hypertension and CVD: a dose–response meta-analysis Bo Xi, Yubei Huang, Kathleen H. Reilly et al. · British Journal Of Nutrition Open access 4 Mar 2015 300
25 Safety and Efficacy of Atorvastatin for Chronic Subdural Hematoma in Chinese Patients Rongcai Jiang et al. · JAMA Neurology Open access 30 Jul 2018 294
26 A genome-wide association study identifies two new risk loci for Graves' disease Xun Chu et al. · Nature Genetics 14 Aug 2011 284
27 Intensive blood pressure control after endovascular thrombectomy for acute ischaemic stroke (ENCHANTED2/MT): a multicentre, open-label, blinded-endpoint, randomised controlled trial Pengfei Yang et al. · The Lancet Open access 28 Oct 2022 264
28 Prevalence of metabolic syndrome and its influencing factors among the Chinese adults: The China Health and Nutrition Survey in 2009 Bo Xi, Dan He, Yuehua Hu et al. · Preventive Medicine Open access 5 Oct 2013 262
29 Short sleep duration predicts risk of metabolic syndrome: A systematic review and meta-analysis Bo Xi, Dan He, Min Zhang et al. · Sleep Medicine Reviews Review 24 Jul 2013 259
30 MALAT1 Is Associated with Poor Response to Oxaliplatin-Based Chemotherapy in Colorectal Cancer Patients and Promotes Chemoresistance through EZH2 Peilong Li, Xin Zhang, Haiyan Wang et al. · Molecular Cancer Therapeutics Open access 9 Jan 2017 251
31 Zinc Silicate/Nano-Hydroxyapatite/Collagen Scaffolds Promote Angiogenesis and Bone Regeneration via the p38 MAPK Pathway in Activated Monocytes Yue Song, Hao Wu, Yi Gao et al. · ACS Applied Materials & Interfaces 17 Mar 2020 229
32 Value of intravenous thrombolysis in endovascular treatment for large-vessel anterior circulation stroke: individual participant data meta-analysis of six randomised trials Charles B.L.M. Majoie et al. · The Lancet ReviewOpen access133 authors 25 Aug 2023 225
33 Preparation and evaluation of quercetin-loaded lecithin-chitosan nanoparticles for topical delivery Guangxi Zhai, Guanlun Guo, Tan et al. · International Journal of Nanomedicine Open access Aug 2011 220
34 CD4+ and CD8+ T cells have opposing roles in breast cancer progression and outcome Yi Huang, Chunling Ma, Qunyuan Zhang et al. · Oncotarget Open access 29 Apr 2015 219
35 Efficacy and safety of a novel anti‐HER2 therapeutic antibody RC48 in patients with HER2‐overexpressing, locally advanced or metastatic gastric or gastroesophageal junction cancer: a single‐arm phase II study Zhi Peng et al. · 癌症:英文版 Open access 19 Oct 2021 211
36 Long noncoding RNA-MEG3 is involved in diabetes mellitus-related microvascular dysfunction Gui-Zhen Qiu, Wei Tian, Haitao Fu et al. · Biochemical and Biophysical Research Communications Feb 2016 197
37 VEGF and BMP-2 promote bone regeneration by facilitating bone marrow stem cell homing and differentiation Wenjie Zhang, Chao Zhu, Yi‐Lei Wu et al. · European Cells and Materials Open access 15 Jan 2014 196
38 Prognostic prediction of systemic immune-inflammation index for patients with gynecological and breast cancers: a meta-analysis Yongfang Ji, Haiyan Wang · World Journal of Surgical Oncology ReviewOpen access 7 Aug 2020 180
39 Global, regional, and national burdens of hip osteoarthritis from 1990 to 2019: estimates from the 2019 Global Burden of Disease Study Ming Fu, Hongming Zhou, Yushi Li et al. · Arthritis Research & Therapy Open access 3 Jan 2022 179
40 Treatment guidelines of lymphatic malformations of the head and neck Qin Zhou, Jia Wei Zheng, Hua Ming et al. · Oral Oncology 10 Sep 2011 167
41 TLR8 signaling enhances tumor immunity by preventing tumor‐induced T‐cell senescence Jian Ye, Chunling Ma, Eddy C. Hsueh et al. · EMBO Molecular Medicine Open access 17 Sep 2014 166
42 The Relationship of Omega-3 Fatty Acids with Dementia and Cognitive Decline: Evidence from Prospective Cohort Studies of Supplementation, Dietary Intake, and Blood Markers Bao‐Zhen Wei, Lin Li, Cheng‐Wen Dong et al. · American Journal of Clinical Nutrition Open access 5 Apr 2023 163
43 Intake of Fruit Juice and Incidence of Type 2 Diabetes: A Systematic Review and Meta-Analysis Bo Xi, Shuangshuang Li, Zhaolu Liu et al. · PLoS ONE ReviewOpen access 28 Mar 2014 163
44 Study of Microbiomes in Aseptically Collected Samples of Human Breast Tissue Using Needle Biopsy and the Potential Role of in situ Tissue Microbiomes for Promoting Malignancy Meng Shen, Bin Chen, Junjie Yang et al. · Frontiers in Oncology Open access 17 Aug 2018 154
45 Efficacy of Aumolertinib (HS-10296) in Patients With Advanced EGFR T790M+ NSCLC: Updated Post-National Medical Products Administration Approval Results From the APOLLO Registrational Trial Shun Lü et al. · Journal of Thoracic Oncology Open access 19 Nov 2021 152
46 Global impact of COVID-19 on stroke care Raul G. Nogueira et al. · International Journal of Stroke Open access273 authors 18 Jan 2021 152
47 Dysbiosis of the gut microbiome is associated with thyroid cancer and thyroid nodules and correlated with clinical index of thyroid function Jiaming Zhang, Fanghua Zhang, Changying Zhao et al. · Endocrine 24 Dec 2018 144
48 Nut consumption in relation to cardiovascular disease risk and type 2 diabetes: a systematic review and meta-analysis of prospective studies Donghao Zhou, Haibing Yu, Fang He et al. · American Journal of Clinical Nutrition ReviewOpen access 8 May 2014 144
49 Association between Common Polymorphism near the MC4R Gene and Obesity Risk: A Systematic Review and Meta-Analysis Bo Xi, Giriraj R. Chandak, Yue Shen et al. · PLoS ONE ReviewOpen access 25 Sep 2012 144
50 Detection and characterization of bacterial nucleic acids in culture-negative synovial tissue and fluid samples from rheumatoid arthritis or osteoarthritis patients Yan Zhao, Bin Chen, Shufeng Li et al. · Scientific Reports Open access 18 Sep 2018 139

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.