| 1 |
Chemotherapy, Bevacizumab, and Cetuximab in Metastatic Colorectal Cancer
Jolien Tol, Miriam Koopman, Annemieke Cats et al. · New England Journal of Medicine
Open access |
4 Feb 2009 |
1,358 |
| 2 |
Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes
Jūlı́us Guðmundsson et al. · Nature Genetics
|
Jul 2007 |
728 |
| 3 |
Assessment of enthesitis in ankylosing spondylitis
L Heuft-Dorenbosch, A Spoorenberg, A van Tubergen et al. · Annals of the Rheumatic Diseases
Open access |
13 Jan 2003 |
685 |
| 4 |
A European Respiratory Society technical standard: exhaled biomarkers in lung disease
Ildikó Horváth et al. · European Respiratory Journal
Open access |
Apr 2017 |
653 |
| 5 |
Sequential versus combination chemotherapy with capecitabine, irinotecan, and oxaliplatin in advanced colorectal cancer (CAIRO): a phase III randomised controlled trial
Miriam Koopman, Ninja F. Antonini, Joep Douma et al. · The Lancet
|
Jul 2007 |
633 |
| 6 |
Hypoxia, Hypoxia-Inducible Transcription Factor, and Macrophages in Human Atherosclerotic Plaques Are Correlated With Intraplaque Angiogenesis
Judith C. Sluimer, Jean‐Marie Gasc, J.L. van Wanroij et al. · Journal of the American College of Cardiology
Open access |
25 Mar 2008 |
469 |
| 7 |
What is the most appropriate radiologic scoring method for ankylosing spondylitis?
Astrid J. B. Wanders, Robert Landewé, Anneke J. P. L. Spoorenberg et al. · Arthritis & Rheumatism
|
Aug 2004 |
378 |
| 8 |
Association of vitamin D metabolite levels with relapse rate and disability in multiple sclerosis
Joost Smolders, P. P. C. A. Menheere, A.G.H. Kessels et al. · Multiple Sclerosis Journal
|
24 Jul 2008 |
345 |
| 9 |
Adjuvant hyperthermic intraperitoneal chemotherapy in patients with locally advanced colon cancer (COLOPEC): a multicentre, open-label, randomised trial
Charlotte E.L. Klaver et al. · The Lancet. Gastroenterology & hepatology
Open access |
29 Jul 2019 |
330 |
| 10 |
Swaddling: A Systematic Review
Bregje E. van Sleuwen, Adèle C. Engelberts, Magda M. Boere‐Boonekamp et al. · PEDIATRICS
ReviewOpen access |
Oct 2007 |
320 |
| 11 |
Influence of Phenotype at Diagnosis and of Other Potential Prognostic Factors on the Course of Inflammatory Bowel Disease
Mariëlle J. L. Romberg-Camps, Pieter C. Dagnelie, A D M Kester et al. · The American Journal of Gastroenterology
|
27 Jan 2009 |
293 |
| 12 |
Clinical Outcomes Among Patients With 1-Year Survival Following Intensive Care Unit Treatment for COVID-19
Hidde Heesakkers, Johannes G. van der Hoeven, Stijn Corsten et al. · JAMA
Open access |
24 Jan 2022 |
288 |
| 13 |
Differentiation between Cell Death Modes Using Measurements of Different Soluble Forms of Extracellular Cytokeratin 18
Gero Kramer, Hamdiye Erdal, Helena J. M. M. Mertens et al. · Cancer Research
|
Mar 2004 |
286 |
| 14 |
The validity of the Beck Depression Inventory as a screening and diagnostic instrument for depression in patients with Parkinson's disease
Albert F.G. Leentjens, Frans R.J. Verhey, Gert-Jan Luijckx et al. · Movement Disorders
|
Nov 2000 |
284 |
| 15 |
Physical function in ankylosing spondylitis is independently determined by both disease activity and radiographic damage of the spine
R. B. M. Landewé, Maxime Dougados, Herman Mielants et al. · Annals of the Rheumatic Diseases
|
16 Jul 2008 |
280 |
| 16 |
Liposomal and Lipid Formulations of Amphotericin B
Robert Janknegt, Siem de Marie, Irma A. J. M. Bakker‐Woudenberg et al. · Clinical Pharmacokinetics
|
Oct 1992 |
274 |
| 17 |
Artificial disc replacement with the modular type SB Charité III: 2-year results in 50 prospectively studied patients
W. S. Zeegers, L. M. L. J. Bohnen, M. Laaper et al. · European Spine Journal
Open access |
2 Jun 1999 |
256 |
| 18 |
The Prevalence of Osteoarthritis of the Intact Hip and Knee Among Traumatic Leg Amputees
Pieter Struyf, Caroline M Van Heugten, Minou W. M. G. C. Hitters et al. · Archives of Physical Medicine and Rehabilitation
Open access |
Mar 2009 |
256 |
| 19 |
Geographical Variations in Sex Ratio Trends over Time in Multiple Sclerosis
María Trojano et al. · PLoS ONE
Open access |
25 Oct 2012 |
239 |
| 20 |
A Multicenter Retrospective Study of the Clinical Results of the LINK®SB CharitéA Intervertebral Prosthesis. The Initial European Experience
Steven L. Griffith, Alexis P. Shelokov, Karin Büttner-Janz et al. · Spine
|
Aug 1994 |
237 |
| 21 |
Work status and productivity costs due to ankylosing spondylitis: comparison of three European countries
Annelies E. R. C. H. Boonen, D van der Heijde, R Landewé et al. · Annals of the Rheumatic Diseases
Open access |
May 2002 |
229 |
| 22 |
Experience of Severe Fatigue Long after Stroke and Its Relation to Depressive Symptoms and Disease Characteristics
Sieberen P. van der Werf, Hans L.P. van den Broek, Herman W.M. Anten et al. · European Neurology
|
2001 |
224 |
| 23 |
Selective mediastinal node irradiation based on FDG-PET scan data in patients with non–small-cell lung cancer: A prospective clinical study
Dirk De Ruysscher, Stofferinus L. Wanders, Erik van Haren et al. · International Journal of Radiation Oncology*Biology*Physics
|
18 Mar 2005 |
216 |
| 24 |
A randomised phase III study on capecitabine, oxaliplatin and bevacizumab with or without cetuximab in first-line advanced colorectal cancer, the CAIRO2 study of the Dutch Colorectal Cancer Group (DCCG). An interim analysis of toxicity
Johan T. M. Tol, Miriam Koopman, Cees J. Rodenburg et al. · Annals of Oncology
Open access |
14 Feb 2008 |
215 |
| 25 |
Employment, work disability, and work days lost in patients with ankylosing spondylitis: a cross sectional study of Dutch patients
Annelies E. R. C. H. Boonen, A Chorus, H Miedema et al. · Annals of the Rheumatic Diseases
Open access |
Apr 2001 |
212 |
| 26 |
Physiology of freezing of gait
Anke H. Snijders, Kaoru Takakusaki, Bettina Debû et al. · Annals of Neurology
|
20 Sep 2016 |
209 |
| 27 |
Cerebrospinal fluid amyloid β40 is decreased in cerebral amyloid angiopathy
Marcel M. Verbeek, Berry P. H. Kremer, Marcel G. M. Olde Rikkert et al. · Annals of Neurology
Open access |
Aug 2009 |
205 |
| 28 |
Halsted Revisited: Internal Mammary Sentinel Lymph Node Biopsy in Breast Cancer
Fred W. C. van der Ent, Roland A. M. Kengen, H.A.G. van der Pol et al. · Annals of Surgery
Open access |
Jul 2001 |
202 |
| 29 |
Exhaled breath condensate in children: Pearls and pitfalls
Philippe P. R. Rosias, Edward Dompeling, Han J. E. Hendriks et al. · Pediatric Allergy and Immunology
|
Feb 2004 |
191 |
| 30 |
Male Sex Is Independently Associated with Faster Disability Accumulation in Relapse-Onset MS but Not in Primary Progressive MS
Karen Ribbons et al. · PLoS ONE
Open access |
5 Jun 2015 |
189 |
| 31 |
Eligibility for concurrent chemotherapy and radiotherapy of locally advanced lung cancer patients: a prospective, population-based study
Dirk De Ruysscher, Anita A.M. Botterweck, Miranda J.M. Dirx et al. · Annals of Oncology
Open access |
22 Aug 2008 |
187 |
| 32 |
Identification of residual metabolic-active areas within individual NSCLC tumours using a pre-radiotherapy 18Fluorodeoxyglucose-PET-CT scan
Hugo J.W.L. Aerts, Angela A.W. van Baardwijk, Steven Petit et al. · Radiotherapy and Oncology
Open access |
30 Mar 2009 |
186 |
| 33 |
Intracranial chondrosarcoma: review of the literature and report of 15 cases
Arthur G. G. C. Korten, H. J W ter Berg, Geert H.J.J. Spincemaille et al. · Journal of Neurology Neurosurgery & Psychiatry
Open access |
Jul 1998 |
178 |
| 34 |
Anthracycline cardiotoxicity in the elderly cancer patient: a SIOG expert position paper
Matti Aapro, C. Bernard-Marty, Etienne G.C. Brain et al. · Annals of Oncology
Open access |
19 Oct 2010 |
169 |
| 35 |
'Modern life' in the epidemiology of inflammatory bowel disease
Maurice G. Rüssel, Leopold G.J.B. Engels, Jean W. M. Muris et al. · European Journal of Gastroenterology & Hepatology
|
Mar 1998 |
164 |
| 36 |
Review article: thiopurines in inflammatory bowel disease
Luc J. J. Derijks, Lennard P. L. Gilissen, Piet M. Hooymans et al. · Alimentary Pharmacology & Therapeutics
Open access |
16 Aug 2006 |
162 |
| 37 |
Phase III trial of liposomal doxorubicin and cyclophosphamide compared with epirubicin and cyclophosphamide as first-line therapy for metastatic breast cancer
Stephen Y.T. Chan, N. G. P. Davidson, Elona Juozaitytė et al. · Annals of Oncology
Open access |
14 Sep 2004 |
155 |
| 38 |
Effects of epoetin alfa on blood transfusions and postoperative recovery in orthopaedic surgery
Eric W. G. Weber, Robert Slappendel, Y. Hémon et al. · European Journal of Anaesthesiology
|
Apr 2005 |
139 |
| 39 |
Childhood asthma: Exhaled markers of airway inflammation, asthma control score, and lung function tests
Philippe P. R. Rosias, Edward Dompeling, Mieke A. Dentener et al. · Pediatric Pulmonology
|
16 Jun 2004 |
137 |
| 40 |
Bilateral Fractures of the Femur Diaphysis in a Patient With Rheumatoid Arthritis on Long-Term Treatment With Alendronate: Clues to the Mechanism of Increased Bone Fragility
Matthijs Paul Somford, Frits W. Draijer, Bregje J.W. Thomassen et al. · Journal of Bone and Mineral Research
|
6 May 2009 |
137 |
| 41 |
The psychology of fatigue in patients with multiple sclerosis: A review
Yvonne Bol, Annelien Duits, Raymond Hupperts et al. · Journal of Psychosomatic Research
|
25 Sep 2008 |
133 |
| 42 |
Botulinum Toxin Injection Versus Surgical Treatment for Tennis Elbow
Stefan B. Keizer, H. P. Rutten, Peter Pilot et al. · Clinical Orthopaedics and Related Research
|
Aug 2002 |
131 |
| 43 |
Persistence on Therapy and Propensity Matched Outcome Comparison of Two Subcutaneous Interferon Beta 1a Dosages for Multiple Sclerosis
Tomáš Kalinčík et al. · PLoS ONE
Open access |
21 May 2013 |
130 |
| 44 |
Direct costs of ankylosing spondylitis and its determinants: an analysis among three European countries
Annelies E. R. C. H. Boonen, D. van der Heijde, R. Landewé et al. · Annals of the Rheumatic Diseases
Open access |
14 Jul 2003 |
127 |
| 45 |
Angiotensin‐converting enzyme 2 (ACE2) expression and activity in human carotid atherosclerotic lesions
Judith C. Sluimer, JM Gasc, Inge Hamming et al. · The Journal of Pathology
Open access |
14 Apr 2008 |
127 |
| 46 |
C-reactive protein in peripheral arterial disease: Relation to severity of the disease and to future cardiovascular events
Tryfon Vainas, Frank R. M. Stassen, Rick de Graaf et al. · Journal of Vascular Surgery
Open access |
Aug 2005 |
126 |
| 47 |
Tumor Volume Combined With Number of Positive Lymph Node Stations Is a More Important Prognostic Factor Than TNM Stage for Survival of Non–Small-Cell Lung Cancer Patients Treated With (Chemo)radiotherapy
Cary Oberije, Dirk De Ruysscher, Hiska L. van der Weide et al. · International Journal of Radiation Oncology*Biology*Physics
|
25 Sep 2007 |
126 |
| 48 |
Omission of elective node irradiation on basis of CT-scans in patients with limited disease small cell lung cancer: A phase II trial
Dirk De Ruysscher, Robert-Harm Bremer, Friederike L.A. Koppe et al. · Radiotherapy and Oncology
|
Sep 2006 |
125 |
| 49 |
Thin GBM nephropathy: Premature glomerular obsolescence is associated with hypertension and late onset renal failure
C. M. G. Nieuwhof, Frans de Heer, Peter de Leeuw et al. · Kidney International
Open access |
May 1997 |
122 |
| 50 |
Sentinel node biopsy in 70 unselected patients with breast cancer: increased feasibility by using 10 mCi radiocolloid in combination with a blue dye tracer
Fred W. C. van der Ent, Roland A. M. Kengen, H.A.G. van der Pol et al. · European Journal of Surgical Oncology
|
Feb 1999 |
121 |