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Most cited papers from Macclesfield College

What are the most cited papers from Macclesfield College?

The most cited paper from Macclesfield College is "Cleavable linkers in antibody–drug conjugates" (Jonathan D. Bargh, Albert Isidro‐Llobet, Jeremy S. Parker et al., 2019), with 659 citations. Next come "Key Green Chemistry research areas from a pharmaceutical manufacturers’ perspective revisited" (625) and "Site-selective modification strategies in antibody–drug conjugates" (460).

Showing 50 of 61 papers. Every paper with more than 20 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Cleavable linkers in antibody–drug conjugates Jonathan D. Bargh, Albert Isidro‐Llobet, Jeremy S. Parker et al. · Chemical Society Reviews Review 2019 659
2 Key Green Chemistry research areas from a pharmaceutical manufacturers’ perspective revisited Marian C. Bryan, Peter J. Dunn, David A. Entwistle et al. · Green Chemistry Open access 2018 625
3 Site-selective modification strategies in antibody–drug conjugates Stephen J. Walsh, Jonathan D. Bargh, Friederike M. Dannheim et al. · Chemical Society Reviews ReviewOpen access 10 Dec 2020 460
4 Making the move towards modernized greener separations: introduction of the analytical method greenness score (AMGS) calculator Michael B. Hicks, William P. Farrell, Christine Aurigemma et al. · Green Chemistry 2019 244
5 Processing of proglucagon to GLP-1 in pancreatic α-cells: is this a paracrine mechanism enabling GLP-1 to act on β-cells? Nicky Whalley, L E Pritchard, David M. Smith et al. · Journal of Endocrinology Open access 27 Jul 2011 177
6 Algorithms for the self-optimisation of chemical reactions Adam D. Clayton, Jamie A. Manson, Connor J. Taylor et al. · Reaction Chemistry & Engineering 2019 162
7 Copper catalyzed Heck-like cyclizations of oxime esters Adele Faulkner, Nicholas J. Race, James S. Scott et al. · Chemical Science Open access 2014 162
8 Online quantitative mass spectrometry for the rapid adaptive optimisation of automated flow reactors Nicholas Holmes, Geoffrey R. Akien, Robert J. D. Savage et al. · Reaction Chemistry & Engineering Open access Dec 2015 133
9 Self-optimisation of the final stage in the synthesis of EGFR kinase inhibitor AZD9291 using an automated flow reactor Nicholas Holmes, Geoffrey R. Akien, A. John Blacker et al. · Reaction Chemistry & Engineering Open access 2016 119
10 Estimating Safely Managed Sanitation in Urban Areas; Lessons Learned From a Global Implementation of Excreta-Flow Diagrams Andy Peal, Barbara A. Evans, SANGARALINGAM AHILAN et al. · Frontiers in Environmental Science Open access 31 Jan 2020 114
11 Hyperpolarisation through reversible interactions with parahydrogen Lyrelle S. Lloyd, Aziz U. R. Asghar, Michael J. Burns et al. · Catalysis Science & Technology Open access 2014 101
12 What is the initiation step of the Grubbs-Hoveyda olefinmetathesiscatalyst? Ian W. Ashworth, Ian H. Hillier, David J. Nelson et al. · Chemical Communications Open access 2011 99
13 Artificial intelligence and automation in computer aided synthesis planning Amol Thakkar, Simon Johansson, Kjell Jorner et al. · Reaction Chemistry & Engineering 5 Nov 2020 98
14 A dual photoredox-nickel strategy for remote functionalization via iminyl radicals: radical ring-opening-arylation, -vinylation and -alkylation cascades Elizabeth M. Dauncey, Shashikant U. Dighe, James J. Douglas et al. · Chemical Science Open access 2019 95
15 A second-generation ligand for the enantioselective rhodium-catalyzed addition of arylboronic acids to alkenylazaarenes Iain D. Roy, Alan R. Burns, Graham Pattison et al. · Chemical Communications Open access 2014 78
16 Enantioselective Narasaka–Heck cyclizations: synthesis of tetrasubstituted nitrogen-bearing stereocenters Nicholas J. Race, Adele Faulkner, Gabriele Fumagalli et al. · Chemical Science Open access 24 Nov 2016 76
17 Ultraclean pure shift NMR Pinelopi Moutzouri, Yingxian Chen, Mohammadali Foroozandeh et al. · Chemical Communications Open access 2017 71
18 Species differences in drug plasma protein binding Nicola Colclough, Linette Ruston, J. Matthew Wood et al. · MedChemComm 2014 70
19 A quantitative reactivity scale for electrophilic fluorinating reagents Neshat Rozatian, Ian W. Ashworth, Graham Sandford et al. · Chemical Science Open access 2018 67
20 Increasing the quantitative bandwidth of NMR measurements Jane Power, Mohammadali Foroozandeh, Ralph W. Adams et al. · Chemical Communications Open access 2016 65
21 Visible-light-mediated generation of nitrile oxides for the photoredox synthesis of isoxazolines and isoxazoles Thomas D. Svejstrup, Wojciech Zawodny, James J. Douglas et al. · Chemical Communications Open access 2016 59
22 Crystal nucleation and growth in a polymorphic system: Ostwald's rule, p -aminobenzoic acid and nucleation transition states J. Black, Peter T. Cardew, Aurora J. Cruz‐Cabeza et al. · CrystEngComm Open access 2018 58
23 Continuous flow Buchwald–Hartwig amination of a pharmaceutical intermediate Polina Yaseneva, Paul B. Hodgson, J. Zakrzewski et al. · Reaction Chemistry & Engineering Open access 23 Nov 2015 56
24 Origins of high catalyst loading in copper( i )-catalysed Ullmann–Goldberg C–N coupling reactions Grant J. Sherborne, Sven Adomeit, Robert Menzel et al. · Chemical Science Open access 2017 55
25 A modular lead-oriented synthesis of diverse piperazine, 1,4-diazepane and 1,5-diazocane scaffolds THOMAS N. JAMES, Paul MacLellan, George M. Burslem et al. · Organic & Biomolecular Chemistry 2014 54
26 Enantioselective reduction of N -alkyl ketimines with frustrated Lewis pair catalysis using chiral borenium ions Dan M. Mercea, Michael G. Howlett, Adam D. Piascik et al. · Chemical Communications 2019 48
27 Long Term Treatment of Multiple Sclerosis with Interferon-?? May Be Cost Effective Malcolm E Kendrick, Katherine Johnson · PharmacoEconomics Jul 2000 47
28 Rapid and robust cysteine bioconjugation with vinylheteroarenes Hikaru Seki, Stephen J. Walsh, Jonathan D. Bargh et al. · Chemical Science Open access 2021 46
29 Dehydrochlorination of PVC in multi-layered blisterpacks using ionic liquids Kamil Oster, Aleksander A. Tedstone, Adam J. Greer et al. · Green Chemistry Open access 2020 46
30 Methodologies for Quantitative Systems Pharmacology (QSP) Models: Design and Estimation Benjamin Ribba, H. P. Grimm, Balaji M. Agoram et al. · CPT Pharmacometrics & Systems Pharmacology Open access 6 Jun 2017 46
31 Online monitoring of a photocatalytic reaction by real-time high resolution FlowNMR spectroscopy Andrew M. R. Hall, Rachael Broomfield-Tagg, Matthew Camilleri et al. · Chemical Communications Open access 13 Nov 2017 45
32 Photoinduced decarboxylative azidation of cyclic amino acids David C. Marcote, Rosie Street-Jeakings, Elizabeth M. Dauncey et al. · Organic & Biomolecular Chemistry Open access 26 Dec 2018 44
33 Solubility prediction from first principles: a density of states approach Simon A. Boothroyd, Andrew Kerridge, Anders Broo et al. · Physical Chemistry Chemical Physics Open access 2018 42
34 Structural characterisation of amorphous solid dispersions via metropolis matrix factorisation of pair distribution function data Harry S. Geddes, Helen Blade, James Francis McCabe et al. · Chemical Communications 2019 40
35 Catalytic direct amidations in tert -butyl acetate using B(OCH 2 CF 3 ) 3 Charlotte E. Coomber, Víctor Laserna, Liam Martin et al. · Organic & Biomolecular Chemistry Open access 2019 40
36 Towards environmentally friendlier Suzuki–Miyaura reactions with precursors of Pd-NHC (NHC = N-heterocyclic carbene) complexes Caroline Zinser, Katie G. Warren, Rebecca E. Meadows et al. · Green Chemistry 2018 40
37 Urogastrone-epidermal growth factor is trophic to the intestinal epithelium of parenterally fed rats Robert A. Goodlad, Thomas J. Wilson, W Lenton et al. · Cellular and Molecular Life Sciences Sep 1985 40
38 An automated computational approach to kinetic model discrimination and parameter estimation Connor J. Taylor, Hikaru Seki, Friederike M. Dannheim et al. · Reaction Chemistry & Engineering Open access 2021 37
39 A controlled study of benzydamine oral rinse (‘Difflam’) in general practice M. W. Whiteside · Current Medical Research and Opinion 1982 35
40 Potent, selective small molecule inhibitors of type III phosphatidylinositol-4-kinase α- but not β-inhibit the phosphatidylinositol signaling cascade and cancer cell proliferation Michael J. Waring, David M. Andrews, Paul Faulder et al. · Chemical Communications 13 Dec 2013 34
41 New N-acyl amino acid-functionalized biodegradable polyesters for pharmaceutical and biomedical applications Vincenzo Taresco, Jiraphong Suksiriworapong, Ioanna Danai Styliari et al. · RSC Advances Open access 2016 33
42 Optimization and sustainability assessment of a continuous flow Ru-catalyzed ester hydrogenation for an important precursor of a β2-adrenergic receptor agonist Michael Prieschl, Jorge García‐Lacuna, Rachel H. Munday et al. · Green Chemistry Open access 2020 31
43 General dual functionalisation of biomacromolecules via a cysteine bridging strategy Stephen J. Walsh, Jessica Iegre, Hikaru Seki et al. · Organic & Biomolecular Chemistry Open access 2020 30
44 Using batch reactor results to calculate optimal flow rates for the scale-up of UV photochemical reactions Luke D. Elliott, Jonathan P. Knowles, C. S. Stacey et al. · Reaction Chemistry & Engineering Open access 2018 29
45 Synthesis and indole coupling reactions of azetidine and oxetane sulfinate salts Anne-Chloé Nassoy, Piotr Raubo, Joseph P. A. Harrity · Chemical Communications 2015 29
46 Synthesis and kinetic resolution of N -Boc-2-arylpiperidines Edward J. Cochrane, Daniele Leonori, Lorraine A. Hassall et al. · Chemical Communications Open access 2014 29
47 Macrocyclisation and functionalisation of unprotected peptides via divinyltriazine cysteine stapling Naomi Robertson, Stephen J. Walsh, Elaine Fowler et al. · Chemical Communications 2019 28
48 A history for consumption ethics Terry Newholm, Sandra Newholm, Deirdre S. Shaw · Business History 10 Sep 2014 28
49 A mechanistic proposal for the protodeboronation of neat boronic acids: boronic acid mediated reaction in the solid state Gary M. Noonan, Andrew G. Leach · Organic & Biomolecular Chemistry Open access 2015 27
50 Definitive screening designs for multistep kinetic models in flow Christopher A. Hone, Alistair Boyd, Anne O’Kearney-McMullan et al. · Reaction Chemistry & Engineering 2019 26

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.