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Most cited papers from MacroGenics (United States)

What are the most cited papers from MacroGenics (United States)?

The most cited paper from MacroGenics (United States) is "CAR T Cells Targeting B7-H3, a Pan-Cancer Antigen, Demonstrate Potent Preclinical Activity Against Pediatric Solid Tumors and Brain Tumors" (Robbie G. Majzner et al., 2019), with 699 citations. Next come "Development of a humanized monoclonal antibody with therapeutic potential against West Nile virus" (521) and "Teplizumab for treatment of type 1 diabetes (Protégé study): 1-year results from a randomised, placebo-controlled trial" (494).

Showing 50 of 61 papers. Every paper with more than 112 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 CAR T Cells Targeting B7-H3, a Pan-Cancer Antigen, Demonstrate Potent Preclinical Activity Against Pediatric Solid Tumors and Brain Tumors Robbie G. Majzner et al. · Clinical Cancer Research Open access 17 Jan 2019 699
2 Development of a humanized monoclonal antibody with therapeutic potential against West Nile virus Theodore Oliphant, Michael J. Engle, Grant E. Nybakken et al. · Nature Medicine Open access 24 Apr 2005 521
3 Teplizumab for treatment of type 1 diabetes (Protégé study): 1-year results from a randomised, placebo-controlled trial Nicole Sherry, William Hagopian, Johnny Ludvigsson et al. · The Lancet Open access 30 Jun 2011 494
4 Conjugation and radiolabeling of monoclonal antibodies with zirconium-89 for PET imaging using the bifunctional chelate p-isothiocyanatobenzyl-desferrioxamine Maria J.W.D. Vosjan, Lars R. Perk, Gerard W.M. Visser et al. · Nature Protocols 25 Mar 2010 449
5 Lethal Antibody Enhancement of Dengue Disease in Mice Is Prevented by Fc Modification Scott J. Balsitis, Katherine L. Williams, Ruben Lachica et al. · PLoS Pathogens Open access 11 Feb 2010 416
6 Absolute and relative nonlinear optical coefficients of KDP, KD*P, BaB/sub 2/O/sub 4/, LiIO/sub 3/, MgO:LiNbO/sub 3/, and KTP measured by phase-matched second-harmonic generation Robert C Eckardt, Hisashi Masuda, Yinxiang Fan et al. · IEEE Journal of Quantum Electronics May 1990 410
7 Paramagnetic lanthanide complexes as PARACEST agents for medical imaging Mark Woods, Donald E. Woessner, A. Dean Sherry · Chemical Society Reviews ReviewOpen access 2006 391
8 Combination immunotherapy: a road map Patrick Alexander Ott, Frank Stephen Hodi, Howard L. Kaufman et al. · Journal for ImmunoTherapy of Cancer Open access 10 Feb 2017 386
9 Structural basis of West Nile virus neutralization by a therapeutic antibody Grant E. Nybakken, Theodore Oliphant, Syd Johnson et al. · Nature Open access Sep 2005 362
10 Efficacy of Margetuximab vs Trastuzumab in Patients With Pretreated ERBB2-Positive Advanced Breast Cancer Hope S. Rugo et al. · JAMA Oncology Open access 23 Jan 2021 353
11 Flotetuzumab as salvage immunotherapy for refractory acute myeloid leukemia Geoffrey L. Uy et al. · Blood Open access 15 Sep 2020 332
12 Development of a Highly Protective Combination Monoclonal Antibody Therapy against Chikungunya Virus Pankaj Pal, Kimberly A. Dowd, James D. Brien et al. · PLoS Pathogens Open access 18 Apr 2013 314
13 Targeting CD73 in the tumor microenvironment with MEDI9447 Carl M. Hay, Erin Sult, Qihui Huang et al. · OncoImmunology Open access 11 Jul 2016 292
14 Development of an Fc-Enhanced Anti–B7-H3 Monoclonal Antibody with Potent Antitumor Activity Deryk T. Loo et al. · Clinical Cancer Research 21 May 2012 287
15 Fc Optimization of Therapeutic Antibodies Enhances Their Ability to Kill Tumor Cells In vitro and Controls Tumor Expansion In vivo via Low-Affinity Activating Fcγ Receptors Jeffrey B. Stavenhagen, Sergey N. Gorlatov, Nadine Tuaillon et al. · Cancer Research Open access 15 Sep 2007 280
16 Implantable Myoelectric Sensors (IMESs) for Intramuscular Electromyogram Recording Richard F ff Weir, Phil R. Troyk, Glen A. DeMichele et al. · IEEE Transactions on Biomedical Engineering Open access 29 Sep 2008 276
17 Global burden of influenza-associated lower respiratory tract infections and hospitalizations among adults: A systematic review and meta-analysis Kathryn E. Lafond et al. · PLoS Medicine ReviewOpen access Mar 2021 269
18 Memory B cells, but not long-lived plasma cells, possess antigen specificities for viral escape mutants Whitney E. Purtha, Thomas F. Tedder, Syd Johnson et al. · The Journal of Experimental Medicine Open access 12 Dec 2011 267
19 In Situ Detection of Apoptosis by the TUNEL Assay: An Overview of Techniques Deryk T. Loo · Methods in molecular biology Book chapter 15 Oct 2010 266
20 Application of dual affinity retargeting molecules to achieve optimal redirected T-cell killing of B-cell lymphoma Paul A. Moore, Wenjun Zhang, G. Jonah Rainey et al. · Blood 8 Feb 2011 263
21 A risk-based bioanalytical strategy for the assessment of antibody immune responses against biological drugs Gopi Shankar, Charles E. Pendley, Kathryn E. Stein · Nature Biotechnology May 2007 262
22 Selective dysregulation of the FcγIIB receptor on memory B cells in SLE Meggan C. Mackay, Anfisa Stanevsky, Tao Wang et al. · The Journal of Experimental Medicine Open access 21 Aug 2006 253
23 Anti-tumor activity and toxicokinetics analysis of MGAH22, an anti-HER2 monoclonal antibody with enhanced Fcγ receptor binding properties Jeffrey L. Nordstrom, Sergey N. Gorlatov, Wenjun Zhang et al. · Breast Cancer Research Open access 30 Nov 2011 251
24 Teplizumab Preserves C-Peptide in Recent-Onset Type 1 Diabetes William Hagopian, Robert J. Ferry, Nicole Sherry et al. · Diabetes Open access 25 Jun 2013 249
25 Identifying baseline immune-related biomarkers to predict clinical outcome of immunotherapy Sacha Gnjatic, Vincenzo Bronte, Laura Rosa Brunet et al. · Journal for ImmunoTherapy of Cancer Open access 12 May 2017 243
26 Trends in Next-Generation Sequencing and a New Era for Whole Genome Sequencing Sang Tae Park, Jayoung Kim · International Neurourology Journal Open access 28 Nov 2016 234
27 First-in-human phase 1 study of margetuximab (MGAH22), an Fc-modified chimeric monoclonal antibody, in patients with HER2-positive advanced solid tumors Yung‐Jue Bang, Giuseppe Giaccone, S.-A. Im et al. · Annals of Oncology Open access 25 Jan 2017 228
28 Structure and Function Analysis of Therapeutic Monoclonal Antibodies against Dengue Virus Type 2 Soila Sukupolvi-Petty, S. Kyle Austin, Michael J. Engle et al. · Journal of Virology Open access Jul 2010 224
29 Immune landscapes predict chemotherapy resistance and immunotherapy response in acute myeloid leukemia Jayakumar Narayanan Vadakekolathu et al. · Science Translational Medicine Open access 3 Jun 2020 218
30 p-Isothiocyanatobenzyl-desferrioxamine: a new bifunctional chelate for facile radiolabeling of monoclonal antibodies with zirconium-89 for immuno-PET imaging Lars R. Perk, Maria J.W.D. Vosjan, Gerard W.M. Visser et al. · European Journal of Nuclear Medicine and Molecular Imaging Open access 17 Sep 2009 216
31 The Development of Therapeutic Antibodies That Neutralize Homologous and Heterologous Genotypes of Dengue Virus Type 1 Bimmi Shrestha, James D. Brien, Soila Sukupolvi-Petty et al. · PLoS Pathogens Open access Apr 2010 213
32 Effector Cell Recruitment with Novel Fv-based Dual-affinity Re-targeting Protein Leads to Potent Tumor Cytolysis and in Vivo B-cell Depletion Syd Johnson, Stephen P. Burke, Ling Ju Huang et al. · Journal of Molecular Biology 10 Apr 2010 197
33 Margetuximab plus pembrolizumab in patients with previously treated, HER2-positive gastro-oesophageal adenocarcinoma (CP-MGAH22–05): a single-arm, phase 1b–2 trial Daniel V.T. Catenacci et al. · The Lancet Oncology 9 Jul 2020 192
34 Small molecule-mediated reprogramming of human hepatocytes into bipotent progenitor cells Yohan Kim, Kyojin Kang, Seung Bum Lee et al. · Journal of Hepatology 19 Sep 2018 184
35 Risk factors for COVID-19-related in-hospital mortality in a high HIV and tuberculosis prevalence setting in South Africa: a cohort study Waasila Jassat et al. · The Lancet HIV Open access1,574 authors 4 Aug 2021 181
36 Targeting CD123 in acute myeloid leukemia using a T-cell–directed dual-affinity retargeting platform Muneera Al-Hussaini, Michael P. Rettig, Julie Ritchey et al. · Blood Open access 3 Nov 2015 179
37 A CD3xCD123 bispecific DART for redirecting host T cells to myelogenous leukemia: Preclinical activity and safety in nonhuman primates Gurunadh Reddy Chichili, Ling Ju Huang, Hua Li et al. · Science Translational Medicine 27 May 2015 174
38 Preclinical Development of MGC018, a Duocarmycin-based Antibody–drug Conjugate Targeting B7-H3 for Solid Cancer Juniper A. Scribner et al. · Molecular Cancer Therapeutics 23 Sep 2020 163
39 TP53 abnormalities correlate with immune infiltration and associate with response to flotetuzumab immunotherapy in AML Jayakumar Narayanan Vadakekolathu et al. · Blood Advances Open access 15 Oct 2020 156
40 Monoclonal antibodies capable of discriminating the human inhibitory Fcγ‐receptor IIB (CD32B) from the activating Fcγ‐receptor IIA (CD32A): biochemical, biological and functional characterization Maria-Concetta Verı́, Sergey N. Gorlatov, Hua Li et al. · Immunology Open access 26 Mar 2007 156
41 Dual checkpoint targeting of B7-H3 and PD-1 with enoblituzumab and pembrolizumab in advanced solid tumors: interim results from a multicenter phase I/II trial Charu Aggarwal et al. · Journal for ImmunoTherapy of Cancer Open access Apr 2022 151
42 T-cell receptor-based therapy: an innovative therapeutic approach for solid tumors Apostolia Maria Tsimberidou, Karlyle Van Morris, Henry Hiep Vo et al. · Journal of Hematology & Oncology Open access 30 Jun 2021 151
43 The genome of Diuraphis noxia, a global aphid pest of small grains Scott J. Nicholson, Michael L. Nickerson, Michael C. Dean et al. · BMC Genomics Open access 4 Jun 2015 150
44 Genotype-Specific Neutralization and Protection by Antibodies against Dengue Virus Type 3 James D. Brien, S. Kyle Austin, Soila Sukupolvi-Petty et al. · Journal of Virology Open access 12 Aug 2010 145
45 Asymptomatic transmission and high community burden of seasonal influenza in an urban and a rural community in South Africa, 2017–18 (PHIRST): a population cohort study Cheryl A. Cohen et al. · The Lancet Global Health Open access 18 May 2021 143
46 Selective blockade of the inhibitory Fcγ receptor (FcγRIIB) in human dendritic cells and monocytes induces a type I interferon response program Kavita M. Dhodapkar, Devi Kanti Banerjee, John Edward Connolly et al. · The Journal of Experimental Medicine Open access 14 May 2007 143
47 The PD-1- and LAG-3-targeting bispecific molecule tebotelimab in solid tumors and hematologic cancers: a phase 1 trial Jason J. Luke et al. · Nature Medicine Open access 19 Oct 2023 139
48 Complement Protein C1q Inhibits Antibody-Dependent Enhancement of Flavivirus Infection in an IgG Subclass-Specific Manner Erin Mehlhop, Camilo Ansarah-Sobrinho, Syd Johnson et al. · Cell Host & Microbe Open access Dec 2007 137
49 Dual-Affinity Re-Targeting proteins direct T cell–mediated cytolysis of latently HIV-infected cells Julia Sung et al. · Journal of Clinical Investigation Open access 27 Sep 2015 134
50 Poorly Neutralizing Cross-Reactive Antibodies against the Fusion Loop of West Nile Virus Envelope Protein ProtectIn Vivovia Fcγ Receptor and Complement-Dependent Effector Mechanisms Matthew R. Vogt, Kimberly A. Dowd, Michael J. Engle et al. · Journal of Virology Open access 15 Sep 2011 132

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.