| 1 |
Perioperative chemotherapy with fluorouracil plus leucovorin, oxaliplatin, and docetaxel versus fluorouracil or capecitabine plus cisplatin and epirubicin for locally advanced, resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4): a randomised, phase 2/3 trial
Salah‐Eddin Al‐Batran et al. · The Lancet
|
11 Apr 2019 |
2,700 |
| 2 |
Mapping and predicting mortality from systemic sclerosis
Muriel Elhaï et al. · Annals of the Rheumatic Diseases
Open access |
23 Aug 2017 |
707 |
| 3 |
Comparison of endoscopic procedures vs Lichtenstein and other open mesh techniques for inguinal hernia repair: a meta-analysis of randomized controlled trials
C.‐G. Schmedt, Stefan Sauerland, R. Bittner · Surgical Endoscopy
Review |
2 Dec 2004 |
443 |
| 4 |
Update of Guidelines for laparoscopic treatment of ventral and incisional abdominal wall hernias (International Endohernia Society (IEHS))—Part A
R. Bittner et al. · Surgical Endoscopy
Open access |
27 Jun 2019 |
383 |
| 5 |
Low Penetrance, Broad Resistance, and Favorable Outcome of Interleukin 12 Receptor β1 Deficiency
Claire Fieschi et al. · The Journal of Experimental Medicine
Open access |
17 Feb 2003 |
307 |
| 6 |
Where in the brain is nonliteral language? A coordinate-based meta-analysis of functional magnetic resonance imaging studies
Alexander Michael Rapp, Dorothee E. Mutschler, Michael Erb · NeuroImage
Review |
Jul 2012 |
258 |
| 7 |
Heart toxicity from breast cancer radiotherapy
Marc Dieter Piroth, René Baumann, Wilfried Budach et al. · Strahlentherapie und Onkologie
Open access |
11 Oct 2018 |
235 |
| 8 |
Safety and clinical outcomes of rituximab therapy in patients with different autoimmune diseases: experience from a national registry (GRAID)
Hans‐Peter Tony et al. · Arthritis Research & Therapy
Open access |
13 May 2011 |
212 |
| 9 |
EAES Consensus Development Conference on endoscopic repair of groin hernias
Marijn M. Poelman et al. · Surgical Endoscopy
Open access |
24 May 2013 |
202 |
| 10 |
Classification of Rectus Diastasis—A Proposal by the German Hernia Society (DHG) and the International Endohernia Society (IEHS)
Wolfgang Matthias Johann Reinpold, Ferdinand Köckerling, R. Bittner et al. · Frontiers in Surgery
Open access |
27 Jan 2019 |
193 |
| 11 |
Effectiveness of triclosan-coated PDS Plus versus uncoated PDS II sutures for prevention of surgical site infection after abdominal wall closure: the randomised controlled PROUD trial
Markus K. Diener et al. · The Lancet
Open access |
7 Apr 2014 |
191 |
| 12 |
Laparoscopic transperitoneal procedure for routine repair of groin hernia
R. Bittner, C-G Schmedt, Jochen Schwarz et al. · British journal of surgery
Open access |
Aug 2002 |
188 |
| 13 |
Comprehensive Re-Sequencing of Adrenal Aldosterone Producing Lesions Reveal Three Somatic Mutations near the KCNJ5 Potassium Channel Selectivity Filter
Tobias Åkerström et al. · PLoS ONE
Open access |
27 Jul 2012 |
186 |
| 14 |
Use of Sodium Fluorescein Solution for Detection of Cerebrospinal Fluid Fistulas: An Analysis of 420 Administrations and Reported Complications in Europe and the United States
Rainer Keerl, Rainer Weber, Wolfgang Draf et al. · The Laryngoscope
|
29 Jan 2004 |
185 |
| 15 |
Imaging-based target volume reduction in chemoradiotherapy for locally advanced non-small-cell lung cancer (PET-Plan): a multicentre, open-label, randomised, controlled trial
Ursula Nestle et al. · The Lancet Oncology
|
12 Mar 2020 |
182 |
| 16 |
Comparison of endoscopic techniques vs Shouldice and other open nonmesh techniques for inguinal hernia repair: a meta-analysis of randomized controlled trials
R. Bittner, Stefan Sauerland, C.‐G. Schmedt · Surgical Endoscopy
Review |
22 Mar 2005 |
181 |
| 17 |
Cooperative Trial CWS-91 for Localized Soft Tissue Sarcoma in Children, Adolescents, and Young Adults
Tobias M. Dantonello, Christoph Int‐Veen, D. Harms et al. · Journal of Clinical Oncology
|
18 Feb 2009 |
178 |
| 18 |
Update of Guidelines for laparoscopic treatment of ventral and incisional abdominal wall hernias (International Endohernia Society (IEHS)): Part B
R. Bittner et al. · Surgical Endoscopy
Open access |
10 Jul 2019 |
173 |
| 19 |
Palmitate-Induced Interleukin-6 Expression in Human Coronary Artery Endothelial Cells
Harald Staiger, Katrin Staiger, Norbert Stefan et al. · Diabetes
|
Dec 2004 |
172 |
| 20 |
Cardiovascular Outcomes with Tirzepatide versus Dulaglutide in Type 2 Diabetes
Stephen James Nicholls et al. · New England Journal of Medicine
Open access |
17 Dec 2025 |
167 |
| 21 |
Apixaban for treatment of embolic stroke of undetermined source (ATTICUS randomized trial): Rationale and study design
Tobias Geisler et al. · International Journal of Stroke
Open access |
23 Nov 2016 |
164 |
| 22 |
Extracorporeal Septoplasty for the Markedly Deviated Septum
Wolfgang Gubisch · Archives of Facial Plastic Surgery
|
Jul 2005 |
160 |
| 23 |
Intra‐articular ganglion cysts of the knee joint: a report of 85 cases and review of the literature
Wilfried K. Krudwig, K Schulte, Carl Heinemann · Knee Surgery Sports Traumatology Arthroscopy
|
18 Sep 2003 |
158 |
| 24 |
Human tumor cell modification by virus infection: an efficient and safe way to produce cancer vaccine with pleiotropic immune stimulatory properties when using Newcastle disease virus
Volker Schirrmacher, C Haas, Riley Bonifer et al. · Gene Therapy
|
1999 |
153 |
| 25 |
Packing in endonasal surgery
Rainer K. Weber, Rainer Keerl, Friedrich Hochapfel et al. · American Journal of Otolaryngology
|
Sep 2001 |
144 |
| 26 |
The Extracorporeal Septum Plasty
Wolfgang Gubisch · Plastic & Reconstructive Surgery
|
Apr 1995 |
144 |
| 27 |
Short-term outcomes from a prospective randomized trial comparing laparoscopic and open surgery for colorectal cancer
Jens Neudecker, Friedt Klein, R. Bittner et al. · British journal of surgery
Open access |
13 Nov 2009 |
143 |
| 28 |
Switching to once-weekly insulin icodec versus once-daily insulin degludec in individuals with basal insulin-treated type 2 diabetes (ONWARDS 2): a phase 3a, randomised, open label, multicentre, treat-to-target trial
Athena Philis‐Tsimikas, Marisse Asong, Edward Franek et al. · The Lancet Diabetes & Endocrinology
|
3 May 2023 |
140 |
| 29 |
Saturated, but Not Unsaturated, Fatty Acids Induce Apoptosis of Human Coronary Artery Endothelial Cells via Nuclear Factor-κB Activation
Katrin Staiger, Harald Staiger, Cora Weigert et al. · Diabetes
|
25 Oct 2006 |
138 |
| 30 |
Brain insulin sensitivity is linked to adiposity and body fat distribution
Stephanie Kullmann, Vera Valenta, Robert J. Wagner et al. · Nature Communications
Open access |
15 Apr 2020 |
136 |
| 31 |
Expression of Ghrelin and its Receptor in Human Tissues
Bianca Ueberberg, Nicole Unger, W Saeger et al. · Hormone and Metabolic Research
|
10 Aug 2009 |
130 |
| 32 |
Excimer Laser Photorefractive Keratectomy for Hyperopia
D. Dausch, Robert Klein, E Schröder · Journal of Refractive Surgery
|
1993 |
128 |
| 33 |
Levels of Antibodies Specific to Tetanus Toxoid,Haemophilus influenzaeType b, and Pneumococcal Capsular Polysaccharide in Healthy Children and Adults
Uwe Schauer, Frank Stemberg, Christian Rieger et al. · Clinical and Vaccine Immunology
Open access |
Mar 2003 |
124 |
| 34 |
Early Diagnosis of Acquired von Willebrand Syndrome (AVWS) is Elementary for Clinical Practice in Patients Treated with ECMO Therapy
Johannes Kalbhenn, René Schmidt, Lea Nakamura et al. · Journal of Atherosclerosis and Thrombosis
Open access |
4 Sep 2014 |
124 |
| 35 |
Heart-sparing radiotherapy techniques in breast cancer patients: a recommendation of the breast cancer expert panel of the German society of radiation oncology (DEGRO)
Breast Cancer Expert Panel of the German Society of Radiation Oncology (DEGRO), Marciana Nona Duma, René Baumann et al. · Strahlentherapie und Onkologie
|
18 Jul 2019 |
123 |
| 36 |
Suprathel®—An innovative, resorbable skin substitute for the treatment of burn victims
C. Uhlig, Matthias Rapp, B. Hartmann et al. · Burns
|
3 Nov 2006 |
123 |
| 37 |
S3-Leitlinie der Deutschen Gesellschaft für Verdauungs- und Stoffwechselkrankheiten und der Deutschen Gesellschaft für Viszeralchirurgie zur Diagnostik und Behandlung von Gallensteinen
Frank Lammert, Michael W. Neubrand, R. Bittner et al. · Zeitschrift für Gastroenterologie
Open access |
Sep 2007 |
120 |
| 38 |
Hypoxia-imaging with 18F-Misonidazole and PET: Changes of kinetics during radiotherapy of head-and-neck cancer
Susanne Martina Eschmann, Frank Paulsen, Claudia Bedeshem et al. · Radiotherapy and Oncology
|
Jun 2007 |
119 |
| 39 |
Laparoscopic inguinal hernia repair: gold standard in bilateral hernia repair? Results of more than 2800 patients in comparison to literature
Constantin Aurel Wauschkuhn, Jochen Schwarz, Ulf Boekeler et al. · Surgical Endoscopy
|
7 May 2010 |
118 |
| 40 |
The nicotinic α6 subunit gene determines variability in chronic pain sensitivity via cross-inhibition of P2X2/3 receptors
Jeffrey S. Wieskopf et al. · Science Translational Medicine
Open access |
13 May 2015 |
118 |
| 41 |
The Impact of the Risk Factor “Age” on the Early Postoperative Results of Surgery for Colorectal Carcinoma and Its Significance for Perioperative Management
F. Marusch, A. Koch, Uwe Schmidt et al. · World Journal of Surgery
|
27 Jun 2005 |
116 |
| 42 |
The Association Between Orthogeriatric Co-Management and Mortality Following Hip Fracture
Kilian Rapp, Clemens Becker, Chris Todd et al. · Deutsches Ärzteblatt international
Open access |
17 Jan 2020 |
115 |
| 43 |
The AESOP robot system in laparoscopic surgery: Increased risk or advantage for surgeon and patient?
Barbara Kraft, C. J�ger, K. Kraft et al. · Surgical Endoscopy
|
19 Jun 2004 |
114 |
| 44 |
Total Gastrectomy
R. Bittner, Michael Butters, Ulrich Martin et al. · Annals of Surgery
Open access |
Jul 1996 |
111 |
| 45 |
Predictive agreement between the fetal arterial oxygen saturation and fetal scalp pH: Results of the German multicenter study
Maritta Kühnert, Birgit Seelbach‐Goebel, Michael Butterwegge · American Journal of Obstetrics and Gynecology
|
Feb 1998 |
110 |
| 46 |
Time-dependent Inhibition of G Protein–coupled Receptor Signaling by Local Anesthetics
Markus W. Hollmann, Susanne Herroeder, Katrin S. Kurz et al. · Anesthesiology
|
23 Mar 2004 |
110 |
| 47 |
Eltrombopag for advanced myelodysplastic syndromes or acute myeloid leukaemia and severe thrombocytopenia (ASPIRE): a randomised, placebo-controlled, phase 2 trial
Moshe Mittelman, Uwe Platzbecker, Boris Vladimirovich Afanasyev et al. · The Lancet Haematology
|
11 Dec 2017 |
108 |
| 48 |
Suprathel, a New Skin Substitute, in the Management of Partial-Thickness Burn Wounds
Hardy P. Schwarze, Markus V. Küntscher, C. Uhlig et al. · Annals of Plastic Surgery
|
Feb 2008 |
105 |
| 49 |
A clinical phase II study with sorafenib in patients with progressive hormone-refractory prostate cancer: a study of the CESAR Central European Society for Anticancer Drug Research-EWIV
Simone Steinbild, K. Mross, Annette Frost et al. · British Journal of Cancer
Open access |
27 Nov 2007 |
104 |
| 50 |
Time-trends in the epidemiology of peptic ulcer bleeding
Christian Ohmann et al. · Scandinavian Journal of Gastroenterology
|
2005 |
103 |