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Institution · Marinus Pharmaceuticals (United States)

Most cited papers from Marinus Pharmaceuticals (United States)

Marinus Pharmaceuticals (United States)

What are the most cited papers from Marinus Pharmaceuticals (United States)?

The most cited paper from Marinus Pharmaceuticals (United States) is "Safety and efficacy of ganaxolone in patients with CDKL5 deficiency disorder: results from the double-blind phase of a randomised, placebo-controlled, phase 3 trial" (Elia M Pestana Knight et al., 2022), with 158 citations. Next come "Safety and efficacy of ganaxolone in patients with CDKL5 deficiency disorder: results from the double-blind phase of a randomised, placebo-controlled, phase 3 trial" (130) and "Why We Need Continuous Pharmaceutical Manufacturing and How to Make It Happen" (121).

Showing 50 of 77 papers. Every paper is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Safety and efficacy of ganaxolone in patients with CDKL5 deficiency disorder: results from the double-blind phase of a randomised, placebo-controlled, phase 3 trial Elia M Pestana Knight et al. · The Lancet Neurology 13 Apr 2022 158
2 Safety and efficacy of ganaxolone in patients with CDKL5 deficiency disorder: results from the double-blind phase of a randomised, placebo-controlled, phase 3 trial Elia Pestana‐Knight, Sam Amin, Nadia Bahi‐Buisson et al. · UCL Discovery (University College London) Open access May 2022 130
3 Why We Need Continuous Pharmaceutical Manufacturing and How to Make It Happen Clive Badman, Charles L. Cooney, Alastair J. Florence et al. · Journal of Pharmaceutical Sciences Open access 2 Aug 2019 121
4 Clinical Evaluation of Ganaxolone in Pediatric and Adolescent Patients with Refractory Epilepsy Vincent A. Pieribone, Julia Y. Tsai, Christine Soufflet et al. · Epilepsia 18 Jul 2007 110
5 Health‐related quality of life assessment in haemophilia patients on prophylaxis therapy: a systematic review of results from prospective clinical trials Abiola O. Oladapo, J. Epstein, E. Williams et al. · Haemophilia Review 17 Jul 2015 84
6 Reactor design and selection for effective continuous manufacturing of pharmaceuticals Chuntian Hu · Journal of Flow Chemistry Open access 18 May 2021 74
7 Is resternotomy in cardiac surgery still a problem?☆ David L.S. Morales, Erin R. Williams, Ranjit John · Interactive Cardiovascular and Thoracic Surgery Open access 4 Jun 2010 68
8 Combating Human Trafficking with Multimodal Deep Models Edmund Tong, Amir Zadeh, Cara Jones et al. Conference paperOpen access 2017 67
9 A randomized controlled trial of ganaxolone in posttraumatic stress disorder Ann M. Rasmusson, Christine E. Marx, Sonia Jain et al. · Psychopharmacology 30 Jun 2017 67
10 Randomized, double‐blind, placebo‐controlled phase 2 study of ganaxolone as add‐on therapy in adults with uncontrolled partial‐onset seizures Michael R. Sperling, Pavel Klein, Julia Y. Tsai · Epilepsia 23 Feb 2017 63
11 Association Between Treatment Progression, Disease Refractoriness, and Burden of Illness Among Hospitalized Patients With Status Epilepticus Elan L. Guterman, John P. Betjemann, Alex A. Aimetti et al. · JAMA Neurology Open access 5 Apr 2021 60
12 Intravenously Administered Ganaxolone Blocks Diazepam-Resistant Lithium-Pilocarpine–Induced Status Epilepticus in Rats: Comparison with Allopregnanolone Michael S. Saporito, John A. Gruner, Amy DiCamillo et al. · Journal of Pharmacology and Experimental Therapeutics Open access 15 Dec 2018 53
13 Intravenous ganaxolone for the treatment of refractory status epilepticus: Results from an open‐label , dose‐finding , phase 2 trial Henrikas Vaitkevicius, Richard Eugene Ramsay, Christa B. Swisher et al. · Epilepsia Open access 24 Jun 2022 52
14 An automated modular assembly line for drugs in a miniaturized plant Chuntian Hu, Christopher J. Testa, Wei Wu et al. · Chemical Communications 9 Dec 2019 41
15 E-factor analysis of a pilot plant for end-to-end integrated continuous manufacturing (ICM) of pharmaceuticals Chuntian Hu, Christopher J. Testa, Stephen C. Born et al. · Green Chemistry 2020 33
16 The effect of omega-3 carboxylic acids on apolipoprotein CIII−containing lipoproteins in severe hypertriglyceridemia Allyson M. Morton, Jeremy D. Furtado, Jane Lee et al. · Journal of clinical lipidology 14 Sep 2016 32
17 GABAA receptor occupancy by subtype selective GABAAα2,3 modulators: PET studies in humans Aurelija Jučaitė, Zsolt Cselényi, Jaakko Lappalainen et al. · Psychopharmacology Open access 24 Dec 2016 31
18 Formulation strategies for the development of high drug-loaded amorphous solid dispersions Hemanth Kumar Mamidi, Siddhant Palekar, Henis J. Patel et al. · Drug Discovery Today 27 Oct 2023 27
19 Detection and Characterization of Human Trafficking Networks Using Unsupervised Scalable Text Template Matching Lin Li, Olga Simek, Angela C. Lai et al. Conference paper Dec 2018 27
20 Long‐term treatment with ganaxolone for seizures associated with cyclin‐dependent kinase‐like 5 deficiency disorder: Two‐year open‐label extension follow‐up Heather E. Olson, Sam Amin, Nadia Bahi‐Buisson et al. · Epilepsia Open access 11 Nov 2023 26
21 Transcranial-Doppler-Measured Vasospasm Severity is Associated with Delayed Cerebral Infarction After Subarachnoid Hemorrhage Samuel B. Snider, Ibrahim Migdady, Sarah L. LaRose et al. · Neurocritical Care 9 Nov 2021 26
22 An experimental study on polymorph control and continuous heterogeneous crystallization of carbamazepine Chuntian Hu, Christopher J. Testa, Brianna T. Shores et al. · CrystEngComm 2019 26
23 Continuous reactive crystallization of an API in PFR-CSTR cascade with in-line PATs Chuntian Hu, Brianna T. Shores, Rachel A. Derech et al. · Reaction Chemistry & Engineering 2020 25
24 Phase 2, placebo-controlled clinical study of oral ganaxolone in PCDH19-clustering epilepsy Joseph E. Sullivan, Boudewijn W. Gunning, Muhammad Zafar et al. · Epilepsy Research Open access 22 Feb 2023 24
25 Identification and Detection of Human Trafficking Using Language Models Jessica Zhu, Lin Li, Cara Jones Conference paper Nov 2019 23
26 Development of an automated multi-stage continuous reactive crystallization system with in-line PATs for high viscosity process Chuntian Hu, Joshua E. Finkelstein, Wei Wu et al. · Reaction Chemistry & Engineering 2018 22
27 Quantifying the Relationship between Large Public Events and Escort Advertising Behavior Benedikt Boecking, Kyle Miller, Emily Barbara Kennedy et al. · Journal of Human Trafficking 20 Apr 2018 22
28 Effects of ganaxolone on non-seizure outcomes in CDKL5 Deficiency Disorder: Double-blind placebo-controlled randomized trial Jenny Anne Downs, Peter Jacoby, Nicola Specchio et al. · European Journal of Paediatric Neurology Open access 17 Jun 2024 21
29 Influences on the trajectory and subsequent outcomes in CDKL5 deficiency disorder Helen Leonard, Mohammed Junaid, Kingsley Wong et al. · Epilepsia Open access 27 Nov 2021 19
30 Neurological complications of cancer immunotherapy (CAR T cells) Daniel B. Rubin, Henrikas Vaitkevicius · Journal of the Neurological Sciences 18 Mar 2021 18
31 Enhancing Patient-Centric Drug Development: Coupling Hot Melt Extrusion with Fused Deposition Modeling and Pressure-Assisted Microsyringe Additive Manufacturing Platforms with Quality by Design Dinesh Nyavanandi, Preethi Mandati, Nithin Vidiyala et al. · Pharmaceutics Open access 25 Dec 2024 17
32 A 12-week extension study to assess the safety and tolerability of naloxegol in patients with noncancer pain and opioid-induced constipation Lynn Roy Webster, Raj Tummala, Ulysses Diva et al. · Journal of Opioid Management Nov 2016 17
33 INFOSHIELD: Generalizable Information-Theoretic Human-Trafficking Detection Meng-Chieh Lee, Catalina Vajiac, Aayushi Kulshrestha et al. Conference paper Apr 2021 16
34 Effect of acorn burying depth on germination, seedling emergence and development of Quercus aliena var. acuteserrata M. J. A. Werger, Ke Guo, Rui Tong Li · Utrecht University Repository (Utrecht University) Open access 2001 14
35 Corroborating various material-sparing techniques with hot melt extrusion for the preparation of triclabendazole amorphous solid dispersions Siddhant Palekar, Hemanth Kumar Mamidi, Yi Guo et al. · International Journal of Pharmaceutics 28 Apr 2023 12
36 A multicenter, open-label trial of ganaxolone in children with PCDH19 epilepsy (P5.236) Jaakko Lappalainen, Michael G. Chez, Joseph E. Sullivan et al. · Neurology 18 Apr 2017 11
37 EEG parameters as endpoints in epilepsy clinical trials - An expert panel opinion paper Jeffrey Buchhalter, Caroline Neuray, Jocelyn Y. Cheng et al. · Epilepsy Research 29 Sep 2022 10
38 Emerging Applications and Regulatory Strategies for Advanced Medicines Manufacturing – Towards the Development of a Platform Approach Jagjit Singh Srai et al. · Journal of Pharmaceutical Sciences 23 Apr 2024 9
39 Complex Metabolism of the Novel Neurosteroid, Ganaxolone, in Humans: A Unique Challenge for Metabolites in Safety Testing Assessment William L. Fitch, Steven M. Smith, Michael S. Saporito et al. · Drug Metabolism and Disposition 19 Mar 2023 9
40 TrafficVis: Visualizing Organized Activity and Spatio-Temporal Patterns for Detecting and Labeling Human Trafficking Catalina Vajiac, Duen Horng Chau, Andreas Olligschlaeger et al. · IEEE Transactions on Visualization and Computer Graphics 6 Oct 2022 9
41 Ejaculate Allocation and Sperm Characteristics Differ among Alternative Male Types in a Species of Fish with Cooperation and Competition among Unrelated Males Suzanne H. Alonzo, Kelly A. Stiver, Holly K. Kindsvater et al. · Cells Open access Oct 2021 8
42 Proof-of-Concept Design of an In-Line pH Neutralization System with Coarse and Fine Adjustments for the Continuous Manufacturing of Pharmaceuticals Wen Ke, Chuntian Hu, Wei Wu et al. · Organic Process Research & Development 6 Aug 2021 8
43 A Multicenter, Double-Blind, Randomized, Placebo-Controlled Phase 3 Trial to Determine the Efficacy and Safety of Ganaxolone as Adjunctive Therapy for Adults with Drug-Resistant Focal-Onset Seizures (P5.237) Jaakko Lappalainen, Julia Y. Tsai, William Amerine et al. · Neurology 18 Apr 2017 7
44 Intravenous Ganaxolone: Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability in Healthy Adults Maciej Ga̧sior, Aatif M. Husain, Megan E. Barra et al. · Clinical Pharmacology in Drug Development Open access 17 Jan 2024 6
45 Neurologic Complications in Patients with Cancer Kathryn B. Holroyd, Daniel B. Rubin, Henrikas Vaitkevicius · Seminars in Neurology Oct 2021 5
46 T-NET: Weakly Supervised Graph Learning for Combatting Human Trafficking Pratheeksha Nair, Jiaqi Liu, Catalina Vajiac et al. · Proceedings of the AAAI Conference on Artificial Intelligence Conference paperOpen access 24 Mar 2024 4
47 Model predictive in vitro dissolution testing in pharmaceutical continuous manufacturing: An equivalence study Qinglin Su, Paul Hermant, Federica Casati et al. · AIChE Journal 26 May 2023 4
48 Multiple High-Grade and Rare Immune-Related Adverse Events in a Colon Cancer Patient with Genomic and Cytokine Profiling Kevin Tyan, Osama Abu-Shawer, Joanna Bagińska et al. · Immunotherapy 13 Jun 2022 4
49 Transcranial Doppler cerebrovascular reactivity: Thresholds for clinical significance in cerebrovascular disease Robert William Regenhardt, Neal M. Nolan, Alvin S. Das et al. · Journal of Neuroimaging Open access 30 Mar 2024 2
50 Extended Duration Safety and Efficacy of Adjunctive Ganaxolone Treatment in Patients with CDKL5 Deficiency Disorder: 8-Month Minimum Open-Label Extension Follow-up (S13.005) Heather E. Olson, Ahsan N. V. Moosa, Eva Rybak et al. · Neurology 3 May 2022 2

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.