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Yipeng Wang, Eckhard Mandelkow� · Nature reviews. Neuroscience
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3 Dec 2015 |
2,308 |
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Structure of 20S proteasome from yeast at 2.4Å resolution
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Structure of TPR Domain–Peptide Complexes
Clemens Scheufler, Achim Brinker, Gleb P. Bourenkov et al. · Cell
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Apr 2000 |
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Tau protein liquid–liquid phase separation can initiate tau aggregation
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22 Feb 2018 |
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Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria
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Oct 2001 |
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Assembly of τ protein into Alzheimer paired helical filaments depends on a local sequence motif ( 306 VQIVYK 311 ) forming β structure
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Open access |
9 May 2000 |
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Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease
Jean C. Augustinack, Anja Schneider, Eva‐Maria Mandelkow et al. · Acta Neuropathologica
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26 Oct 2001 |
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Structure of Functionally Activated Small Ribosomal Subunit at 3.3 Å Resolution
Frank Schluenzen, Ante Tocilj, Raz Zarivach et al. · Cell
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Sep 2000 |
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Tau in Alzheimer's disease
Eva‐Maria Mandelkow, E Mandelkow · Trends in Cell Biology
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High Resolution Structure of the Large Ribosomal Subunit from a Mesophilic Eubacterium
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Nov 2001 |
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Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress
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18 Mar 2002 |
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MARK, a Novel Family of Protein Kinases That Phosphorylate Microtubule-Associated Proteins and Trigger Microtubule Disruption
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Apr 1997 |
887 |
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Biochemistry and Cell Biology of Tau Protein in Neurofibrillary Degeneration
Eva‐Maria Mandelkow, Eva‐Maria Mandelkow, Eva‐Maria Mandelkow et al. · Cold Spring Harbor Perspectives in Medicine
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20 Mar 2012 |
874 |
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Overexpression of Tau Protein Inhibits Kinesin-dependent Trafficking of Vesicles, Mitochondria, and Endoplasmic Reticulum: Implications for Alzheimer's Disease
Andreas Ebneth, Robert Godemann, Karsten Stamer et al. · The Journal of Cell Biology
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2 Nov 1998 |
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Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: Distinction between PHF-like immunoreactivity and microtubule binding
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Jul 1993 |
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A sequence of cytoskeleton changes related to the formation of neurofibrillary tangles and neuropil threads
F. Braak, Heiko Braak, Eva‐Maria Mandelkow · Acta Neuropathologica
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Jun 1994 |
761 |
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Indirubins Inhibit Glycogen Synthase Kinase-3β and CDK5/P25, Two Protein Kinases Involved in Abnormal Tau Phosphorylation in Alzheimer's Disease
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2001 |
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Duplicated P5CS genes of Arabidopsis play distinct roles in stress regulation and developmental control of proline biosynthesis
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19 Sep 2007 |
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Aβ Oligomers Cause Localized Ca 2+ Elevation, Missorting of Endogenous Tau into Dendrites, Tau Phosphorylation, and Destruction of Microtubules and Spines
Hans Zempel, Edda Thies, Eckhard Mandelkow� et al. · Journal of Neuroscience
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8 Sep 2010 |
692 |
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Structural Polymorphism of 441-Residue Tau at Single Residue Resolution
Marco D. Mukrasch, Stefan Bibow, Jegannath Korukottu et al. · PLoS Biology
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12 Feb 2009 |
676 |
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Domains of tau Protein and Interactions with Microtubules
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16 Oct 1994 |
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Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing
Yipeng Wang, Marta Martínez‐Vicente, Ulrike Krüger et al. · Human Molecular Genetics
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4 Aug 2009 |
618 |
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Mutations of Tau Protein in Frontotemporal Dementia Promote Aggregation of Paired Helical Filaments by Enhancing Local β-Structure
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Dec 2001 |
601 |
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Phosphorylation that Detaches Tau Protein from Microtubules (Ser262, Ser214) Also Protects It against Aggregation into Alzheimer Paired Helical Filaments
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Mar 1999 |
575 |
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An Arabidopsis Callose Synthase, GSL5, Is Required for Wound and Papillary Callose Formation
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10 Oct 2003 |
572 |
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Microtubule dynamics and microtubule caps: a time-resolved cryo-electron microscopy study.
Eckhard Mandelkow�, Eckhard Mandelkow�, Ron A. Milligan · The Journal of Cell Biology
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Sep 1991 |
572 |
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Mitogen activated protein (MAP) kinase transforms tau protein into an Alzheimer‐like state.
Gerard Drewes, B. Lichtenberg-Kraag, Frank Döring et al. · The EMBO Journal
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Structural studies of tau protein and Alzheimer paired helical filaments show no evidence for beta-structure.
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RNA stimulates aggregation of microtubule‐associated protein tau into Alzheimer‐like paired helical filaments
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16 Dec 1996 |
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Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3
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17 Apr 2001 |
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Glycogen synthase kinase‐3 and the Alzheimer‐like state of microtubule‐associated protein tau
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21 Dec 1992 |
513 |
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The switch of tau protein to an Alzheimer‐like state includes the phosphorylation of two serine‐proline motifs upstream of the microtubule binding region.
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Apr 1992 |
483 |
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Alzheimer-like paired helical filaments and antiparallel dimers formed from microtubule-associated protein tau in vitro.
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Aug 1992 |
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Abnormal Alzheimer‐like phosphorylation of tau‐protein by cyclin‐dependent kinases cdk2 and cdk5
Karlheinz Baumann, Eva‐Maria Mandelkow, E.-M. Mandelkow et al. · FEBS Letters
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28 Dec 1993 |
477 |
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Structure and mechanism of the aberrant ba3‐cytochrome c oxidase from Thermus thermophilus
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17 Apr 2000 |
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Microtubules and microtubule-associated proteins
Eckhard Mandelkow, Eva‐Maria Mandelkow · Current Opinion in Cell Biology
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Inhibition of cyclin-dependent kinases, GSK-3β and CK1 by hymenialdisine, a marine sponge constituent
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Global Hairpin Folding of Tau in Solution
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28 Jan 2006 |
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Structural Basis for the Function of the Ribosomal L7/12 Stalk in Factor Binding and GTPase Activation
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The structures of HslU and the ATP-dependent protease HslU–HslV
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“Lest we forget you — methylene blue …”
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13 Feb 2011 |
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Rapid Assembly of Alzheimer-like Paired Helical Filaments from Microtubule-Associated Protein Tau Monitored by Fluorescence in Solution
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24 Jun 1998 |
411 |
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The Crystal Structure of Dimeric Kinesin and Implications for Microtubule-Dependent Motility
Frank Kozielski, Stefan Sack, Alexander Marx et al. · Cell
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Dec 1997 |
411 |
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Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses
Eckhard Mandelkow�, E Mandelkow · Neurobiology of Aging
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24 Nov 2003 |
402 |
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Structure of cytochrome c nitrite reductase
Oliver Einsle, Albrecht Messerschmidt, Petra Stach et al. · Nature
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Microtubule-associated Protein/Microtubule Affinity-regulating Kinase (p110mark)
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Tau aggregation is driven by a transition from random coil to beta sheet structure
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Paullones are potent inhibitors of glycogen synthase kinase‐3β and cyclin‐dependent kinase 5/p25
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Oct 2000 |
376 |
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Oxidation of cysteine-322 in the repeat domain of microtubule-associated protein tau controls the in vitro assembly of paired helical filaments.
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29 Aug 1995 |
375 |
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In Vivo Microdialysis Reveals Age-Dependent Decrease of Brain Interstitial Fluid Tau Levels in P301S Human Tau Transgenic Mice
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14 Sep 2011 |
363 |