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Most cited papers from MaxCyte (United States)

What are the most cited papers from MaxCyte (United States)?

The most cited paper from MaxCyte (United States) is "CRISPR-Cas9 gene repair of hematopoietic stem cells from patients with X-linked chronic granulomatous disease" (Suk See De Ravin, Linhong Li, Xiaolin Wu et al., 2017), with 262 citations. Next come "Targeted gene addition in human CD34+ hematopoietic cells for correction of X-linked chronic granulomatous disease" (195) and "Expression of chimeric antigen receptors in natural killer cells with a regulatory-compliant non-viral method" (141).

Showing 50 of 78 papers. Every paper is listed.

Most cited papers, sortable by citations and release date
#Paper
1 CRISPR-Cas9 gene repair of hematopoietic stem cells from patients with X-linked chronic granulomatous disease Suk See De Ravin, Linhong Li, Xiaolin Wu et al. · Science Translational Medicine 11 Jan 2017 262
2 Targeted gene addition in human CD34+ hematopoietic cells for correction of X-linked chronic granulomatous disease Suk See De Ravin et al. · Nature Biotechnology Open access 7 Mar 2016 195
3 Expression of chimeric antigen receptors in natural killer cells with a regulatory-compliant non-viral method Lin Li, L N Liu, Stephanie Feller et al. · Cancer Gene Therapy Open access 11 Sep 2009 141
4 Selective Field Effects on Intracellular Vacuoles and Vesicle Membranes with Nanosecond Electric Pulses Ephrem Tekle, Hammou Oubrahim, Sergey M. Dzekunov et al. · Biophysical Journal Open access 8 Apr 2005 137
5 Efficient mRNA-Based Genetic Engineering of Human NK Cells with High-Affinity CD16 and CCR7 Augments Rituximab-Induced ADCC against Lymphoma and Targets NK Cell Migration toward the Lymph Node-Associated Chemokine CCL19 Mattias Carlsten, Emily Ruth Levy, Amrita D. Karambelkar et al. · Frontiers in Immunology Open access 21 Mar 2016 119
6 CD38 knockout natural killer cells expressing an affinity optimized CD38 chimeric antigen receptor successfully target acute myeloid leukemia with reduced effector cell fratricide Mark E. Gurney, Arwen Stikvoort, Emma Nolan et al. · Haematologica Open access 30 Dec 2020 113
7 Development of Anti-Human Mesothelin-Targeted Chimeric Antigen Receptor Messenger RNA–Transfected Peripheral Blood Lymphocytes for Ovarian Cancer Therapy Chien‐Fu Hung, Xuequn Xu, Linhong Li et al. · Human Gene Therapy Open access 16 Jan 2018 81
8 Enhanced homology-directed repair for highly efficient gene editing in hematopoietic stem/progenitor cells Suk See De Ravin et al. · Blood Open access 24 Feb 2021 76
9 A roadmap for cost-of-goods planning to guide economic production of cell therapy products Yonatan Y. Lipsitz, William D. Milligan, Ian FitzPatrick et al. · Cytotherapy Open access 19 Sep 2017 76
10 Highly Efficient, Large Volume Flow Electroporation Linhong Li, Rama Shivakumar, Stephanie Feller et al. · Technology in Cancer Research & Treatment Oct 2002 63
11 CHO-S Antibody Titers >1 Gram/Liter Using Flow Electroporation-Mediated Transient Gene Expression followed by Rapid Migration to High-Yield Stable Cell Lines Krista K. Steger, James P. Brady, Weili Wang et al. · SLAS DISCOVERY Open access 18 Dec 2014 53
12 Preclinical Evaluation of CRISPR-Edited CAR-NK-92 Cells for Off-the-Shelf Treatment of AML and B-ALL Guillermo Ureña-Bailén, Jérôme-Maurice Dobrowolski, Yujuan Hou et al. · International Journal of Molecular Sciences Open access 24 Oct 2022 50
13 Assessing the gang-level and community-level effects of the Philadelphia Focused Deterrence strategy Caterina G. Roman, Nathan W. Link, Jordan M. Hyatt et al. · Journal of Experimental Criminology 22 Jun 2018 48
14 Homology-independent targeted insertion (HITI) enables guided CAR knock-in and efficient clinical scale CAR-T cell manufacturing Hyatt Balke‐Want, Vimal Keerthi, Nikolaos Gkitsas-Long et al. · Molecular Cancer Open access 26 Jun 2023 46
15 Cutting Edge: TCR-Induced NAB2 Enhances T Cell Function by Coactivating IL-2 Transcription Samuel L. Collins, Lawrence A. Wolfraim, Charles G. Drake et al. · The Journal of Immunology Dec 2006 43
16 Simulated evidence on the prospects of treating more drug-involved offenders Avinash Singh Bhati, John Roman · Journal of Experimental Criminology Mar 2010 33
17 Efficient Large Volume Lentiviral Vector Production Using Flow Electroporation Scott R. Witting, Lin-Hong Li, Aparna C. Jasti et al. · Human Gene Therapy Open access 21 Sep 2011 32
18 Heterologous survey of 130 DNA transposons in human cells highlights their functional divergence and expands the genome engineering toolbox Tongtong Zhang et al. · Cell Open access 5 Jun 2024 28
19 Preclinical evaluation for engraftment of CD34+ cells gene-edited at the sickle cell disease locus in xenograft mouse and non-human primate models Naoya Uchida, Linhong Li, Tina Nassehi et al. · Cell Reports Medicine Open access Apr 2021 27
20 Optimized electroporation of CRISPR-Cas9/gRNA ribonucleoprotein complex for selection-free homologous recombination in human pluripotent stem cells Huaigeng Xu, Yuto Kita, Uikyu Bang et al. · STAR Protocols Open access 16 Nov 2021 25
21 Large Volume Flow Electroporation of mRNA: Clinical Scale Process Linhong Li, Cornell Allen, Rama Shivakumar et al. · Methods in molecular biology Book chapter 8 Nov 2012 25
22 A non-viral gene delivery system designed for clinical use Joseph C. Fratantoni, Sergey M. Dzekunov, Vin Singh et al. · Cytotherapy 2003 23
23 Rapid, in vivo, evaluation of antiangiogenic and antineoplastic gene products by nonviral transfection of tumor cells Jonathan M. Weiss, Rama Shivakumar, Stephanie Feller et al. · Cancer Gene Therapy 19 Mar 2004 22
24 Delivery of Whole Tumor Lysate into Dendritic Cells for Cancer Vaccination Linda N. Liu, Rama Shivakumar, Cornell Allen et al. · Methods in molecular biology Book chapter 2008 22
25 Efficient electroporation of neuronal cells using synthetic oligonucleotides: identifying duplex RNA and antisense oligonucleotide activators of human frataxin expression Xiulong Shen, Sharon Beasley, Jennifer N. Putman et al. · RNA Open access 31 May 2019 21
26 Non-viral TRAC-knocked-in CD19KICAR-T and gp350KICAR-T cells tested against Burkitt lymphomas with type 1 or 2 EBV infection: In vivo cellular dynamics and potency Tobias Braun, Alina Pruene, Milita Darguzyte et al. · Frontiers in Immunology Open access 24 Mar 2023 20
27 Rapid and efficient nonviral gene delivery of CD154 to primary chronic lymphocytic leukemia cells Letai Li, Eleonora Biagi, Cornell Allen et al. · Cancer Gene Therapy 5 Aug 2005 20
28 Clinical scale electroloading of mature dendritic cells with melanoma whole tumor cell lysate is superior to conventional lysate co-incubation in triggering robust in vitro expansion of functional antigen-specific CTL Lawrence A. Wolfraim, Masashi Takahara, Angelia M. Viley et al. · International Immunopharmacology 8 Feb 2013 18
29 CRISPR-Cas9-Based Gene Knockout of Immune Checkpoints in Expanded NK Cells Tahereh Mohammadian Gol, Miso Kim, Ralph Sinn et al. · International Journal of Molecular Sciences Open access 8 Nov 2023 16
30 MAGT1 messenger RNA-corrected autologous T and natural killer cells for potential cell therapy in X-linked immunodeficiency with magnesium defect, Epstein-Barr virus infection and neoplasia disease Julie Brault, Ronald J. Meis, Linhong Li et al. · Cytotherapy 10 Oct 2020 15
31 Elucidation of the liver pathophysiology of COVID-19 patients using liver-on-a-chips Sayaka Deguchi, Kaori Kosugi, Rina Hashimoto et al. · PNAS Nexus Open access Mar 2023 14
32 Final overall survival analysis of the phase 3 HERITAGE study demonstrates equivalence of trastuzumab-dkst to trastuzumab in HER2-positive metastatic breast cancer Hope S. Rugo et al. · Breast Cancer Research and Treatment Open access 14 Jun 2021 14
33 Comparison of two CD40-ligand/interleukin-2 vaccines in patients with chronic lymphocytic leukemia Fatma Visal Okur, Eric S. Yvon, Ettore Biagi et al. · Cytotherapy Open access 12 Jul 2011 14
34 Efficient Responses in a Murine Renal Tumor Model by Electroloading Dendritic Cells With Whole-Tumor Lysate Jonathan M. Weiss, Cornell Allen, Rama Shivakumar et al. · Journal of Immunotherapy 13 Oct 2005 13
35 SARS-CoV-2-induced disruption of a vascular bed in a microphysiological system caused by type-I interferon from bronchial organoids Kazuya Fujimoto, Yoshikazu Kameda, Yuta Nagano et al. · Lab on a Chip Open access 2024 12
36 Challenges in Gene Therapy for Somatic Reverted Mosaicism in X-Linked Combined Immunodeficiency by CRISPR/Cas9 and Prime Editing Yujuan Hou, Guillermo Ureña-Bailén, Tahereh Mohammadian Gol et al. · Genes Open access 13 Dec 2022 12
37 Multiple genetic programs contribute to CD4 T cell memory differentiation and longevity by maintaining T cell quiescence Nianbin Song, Srona Sengupta, Stanislav Khoruzhenko et al. · Cellular Immunology Open access 6 Sep 2020 12
38 Bioprocessing considerations for generation of iPSCs intended for clinical application: perspectives from the ISCT Emerging Regenerative Medicine Technology working group Hannah W. Song, Jennifer N. Solomon, Fernanda Masri et al. · Cytotherapy Open access Jun 2024 11
39 Selecting a Cell Engineering Methodology During Cell Therapy Product Development Lauren M. Timmins, Alexandra Burr, Kristina Carroll et al. · Cell Transplantation Open access 2021 10
40 CGMP-compliant, clinical scale, non-viral platform for efficient gene editing using CRISPR/Cas9 L. Li, P. Natarajan, Cornell Allen et al. · Cytotherapy 14 Mar 2014 10
41 Supporting the Manufacturing of Medical Supplies in Africa: Collaboration Between Africa CDC, Partners, and Member States Mohammed Abdulaziz, Hanna Idris-Dantata, Tochi Joy Okwor et al. · Global Health Science and Practice Open access 15 Sep 2023 9
42 Clinical-Grade mRNA Electroporation of NK Cells: A Novel and Highly Efficient Method to Genetically Reprogram Human NK Cells for Cancer Immunotherapy Mattias Carlsten, Linhong Li, Su Su et al. · Blood 6 Dec 2014 9
43 Accelerated generation of gene‐engineered monoclonal CHO cell lines using FluidFM nanoinjection and CRISPR/Cas9 Justin S. Antony, Anabel Migenda Herranz, Tahereh Mohammadian Gol et al. · Biotechnology Journal Open access Apr 2024 8
44 Mass balance, routes of excretion, and pharmacokinetics of investigational oral [14C]-alisertib (MLN8237), an Aurora A kinase inhibitor in patients with advanced solid tumors Xiaofei Zhou, Sandeepraj Pusalkar, Swapan K. Chowdhury et al. · Investigational New Drugs 6 Nov 2018 7
45 ORAOV1 , CCND1 , and MIR548K Are the Driver Oncogenes of the 11q13 Amplicon in Squamous Cell Carcinoma Céline I. Mahieu, Andrew G. Mancini, Ellee Pisey Vikram et al. · Molecular Cancer Research Open access 6 Nov 2023 6
46 Enrichment of Allelic Editing Outcomes by Prime Editing in Induced Pluripotent Stem Cells Ryo Niwa, Tomoko Matsumoto, Alexander Y. Liu et al. · The CRISPR Journal Open access Oct 2024 5
47 Preparation of NanoMEDIC Extracellular Vesicles to Deliver CRISPR-Cas9 Ribonucleoproteins for Genomic Exon Skipping Kei Watanabe, Peter Gee, Akitsu Hotta · Methods in molecular biology Book chapter 18 Nov 2022 5
48 NADPH oxidase correction by mRNA transfection of apheresis granulocytes in chronic granulomatous disease Suk See De Ravin et al. · Blood Advances Open access 7 Dec 2020 4
49 Highly efficient gene knockout in tumor-infiltrating lymphocytes by adenine base editing Morteza Hafezi, Raphaël Genolet, Leila Hadadi et al. · Molecular Therapy Oncology Open access 22 Aug 2025 3
50 A phase I study of intraperitoneal MCY-M11 Anti-mesothelin CAR for women with platinum resistant high grade serous adenocarcinoma of the ovary, primary peritoneum, or fallopian tube, or subjects with peritoneal mesothelioma with recurrence after prior chemotherapy Christina M. Annunziata, C. Dansky-Ullmann, Armin Ghobadi et al. · Annals of Oncology Open access Oct 2019 3

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.