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Most cited papers from Medisch Centrum Alkmaar

What are the most cited papers from Medisch Centrum Alkmaar?

The most cited paper from Medisch Centrum Alkmaar is "Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease" (Paul M. Ridker et al., 2017), with 9,517 citations. Next come "70-Gene Signature as an Aid to Treatment Decisions in Early-Stage Breast Cancer" (2,097) and "Delirium in Elderly Patients and the Risk of Postdischarge Mortality, Institutionalization, and Dementia" (2,024).

Showing 50 of 60 papers. Every paper with more than 284 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease Paul M. Ridker et al. · New England Journal of Medicine Open access 27 Aug 2017 9,517
2 70-Gene Signature as an Aid to Treatment Decisions in Early-Stage Breast Cancer Fátima Cardoso et al. · New England Journal of Medicine Open access 24 Aug 2016 2,097
3 Delirium in Elderly Patients and the Risk of Postdischarge Mortality, Institutionalization, and Dementia Joost Witlox, Lisa S. M. Eurelings, Jos F. M. de Jonghe et al. · JAMA 27 Jul 2010 2,024
4 A Step-up Approach or Open Necrosectomy for Necrotizing Pancreatitis Hjalmar C. van Santvoort et al. · New England Journal of Medicine Open access 21 Apr 2010 1,726
5 Use of clopidogrel with or without aspirin in patients taking oral anticoagulant therapy and undergoing percutaneous coronary intervention: an open-label, randomised, controlled trial Willem J.M. Dewilde, Tom Oirbans, Freek W.A. Verheugt et al. · The Lancet 12 Feb 2013 1,725
6 Early combined immunosuppression or conventional management in patients with newly diagnosed Crohn's disease: an open randomised trial Geert D’Haens et al. · The Lancet Feb 2008 1,243
7 Randomised comparison of combined step-down prednisolone, methotrexate and sulphasalazine with sulphasalazine alone in early rheumatoid arthritis Maarten Boers, Arco C. Verhoeven, Harry M. Markusse et al. · The Lancet Open access Aug 1997 1,078
8 Lenient versus Strict Rate Control in Patients with Atrial Fibrillation Isabelle C. Van Gelder, Hessel F. Groenveld, Harry J.G.M. Crijns et al. · New England Journal of Medicine 15 Mar 2010 1,036
9 Apixaban with Antiplatelet Therapy after Acute Coronary Syndrome John Hunter Alexander et al. · New England Journal of Medicine Open access 24 Jul 2011 1,002
10 Prasugrel versus Clopidogrel for Acute Coronary Syndromes without Revascularization Matthew T. Roe et al. · New England Journal of Medicine Open access 26 Aug 2012 884
11 Effectiveness of positron emission tomography in the preoperative assessment of patients with suspected non-small-cell lung cancer: the PLUS multicentre randomised trial Harm van Tinteren, Otto S. Hoekstra, Egbert Frederik Smit et al. · The Lancet Apr 2002 865
12 Altered PTEN Expression as a Diagnostic Marker for the Earliest Endometrial Precancers George L. Mutter · JNCI Journal of the National Cancer Institute 7 Jun 2000 850
13 Modern modelling techniques are data hungry: a simulation study for predicting dichotomous endpoints Tjeerd van der Ploeg, Peter C. Austin, Ewout Willem Steyerberg · BMC Medical Research Methodology Open access Dec 2014 842
14 Current evidence on hospital antimicrobial stewardship objectives: a systematic review and meta-analysis Emelie C Schuts, Marlies Hulscher, Johan Willem Mouton et al. · The Lancet Infectious Diseases Review 2 Mar 2016 782
15 Thrombin-Receptor Antagonist Vorapaxar in Acute Coronary Syndromes Pierluigi Tricoci et al. · New England Journal of Medicine Open access 13 Nov 2011 757
16 A Conservative and Minimally Invasive Approach to Necrotizing Pancreatitis Improves Outcome Hjalmar C. van Santvoort et al. · Gastroenterology Open access 10 Jul 2011 748
17 Population-based epidemiology, malignancy risk, and outcome of primary sclerosing cholangitis Kirsten Boonstra, Rinse Karel Weersma, Karel J. van Erpecum et al. · Hepatology Open access 14 Jun 2013 732
18 Pharmacodynamic effect and clinical efficacy of clopidogrel and prasugrel with or without a proton-pump inhibitor: an analysis of two randomised trials Michelle L. O’Donoghue, Eugene Braunwald, Elliott Marshall Antman et al. · The Lancet Sep 2009 728
19 Predictors of Coronary Stent Thrombosis Jochem Wouter van Werkum, Antonius A.C.M. Heestermans, Anoek Zomer et al. · Journal of the American College of Cardiology Open access Apr 2009 700
20 Imaging techniques for assessment of inflammatory bowel disease: Joint ECCO and ESGAR evidence-based consensus guidelines Julián Panés et al. · Journal of Crohn s and Colitis Open access 16 Apr 2013 673
21 Haloperidol Prophylaxis for Elderly Hip‐Surgery Patients at Risk for Delirium: A Randomized Placebo‐Controlled Study Kees J. Kalisvaart, Jos F. M. de Jonghe, Marja J. Bogaards et al. · Journal of the American Geriatrics Society Open access 21 Sep 2005 652
22 Frailty screening methods for predicting outcome of a comprehensive geriatric assessment in elderly patients with cancer: a systematic review Marije Emilie Hamaker, J.M. Jonker, Sophia E de Rooij et al. · The Lancet Oncology Review 28 Sep 2012 647
23 Cut-Off Points for Mild, Moderate, and Severe Pain on the Numeric Rating Scale for Pain in Patients with Chronic Musculoskeletal Pain: Variability and Influence of Sex and Catastrophizing Anne M. Boonstra, Roy E. Stewart, Albere J. A. Köke et al. · Frontiers in Psychology Open access 29 Sep 2016 646
24 X-linked adrenoleukodystrophy (X-ALD): clinical presentation and guidelines for diagnosis, follow-up and management Marc Engelen, Stephan Kemp, Marianne de Visser et al. · Orphanet Journal of Rare Diseases Open access 2012 584
25 Accuracy of Currently Available Techniques for Prediction of Functional Recovery After Revascularization in Patients With Left Ventricular Dysfunction Due to Chronic Coronary Artery Disease: Comparison of Pooled Data Jeroen Joost Bax, William C. Wijns, Jan Hein Cornel et al. · Journal of the American College of Cardiology Open access Nov 1997 564
26 Early Invasive versus Selectively Invasive Management for Acute Coronary Syndromes Robbert J. de Winter, Fons Windhausen, Jan Hein Cornel et al. · New England Journal of Medicine Open access 14 Sep 2005 538
27 Speaking up for patient safety by hospital-based health care professionals: a literature review Ayako Okuyama, Cordula Wagner, Bart Bijnen · BMC Health Services Research Open access 8 Feb 2014 533
28 Maintenance treatment with capecitabine and bevacizumab in metastatic colorectal cancer (CAIRO3): a phase 3 randomised controlled trial of the Dutch Colorectal Cancer Group Lieke H. J. Simkens et al. · The Lancet Open access 10 Apr 2015 529
29 Effect of Azithromycin Maintenance Treatment on Infectious Exacerbations Among Patients With Non–Cystic Fibrosis Bronchiectasis Josje Altenburg, Casper S. de Graaff, Ymkje Stienstra et al. · JAMA 26 Mar 2013 503
30 The Incidence of Cerebral Venous Thrombosis Jonathan M. Coutinho, Susanna Maria Zuurbier, Majid Aramideh et al. · Stroke 21 Sep 2012 473
31 Pulmonary exacerbation in adults with bronchiectasis: a consensus definition for clinical research Adam T. Hill et al. · European Respiratory Journal Open access Jun 2017 463
32 Low-Grade Dysplasia in Barrett's Esophagus: Overdiagnosed and Underestimated Wouter L. Curvers, Fiebo J. ten Kate, Kausilia Krishnawatie Krishnadath et al. · The American Journal of Gastroenterology 11 May 2010 463
33 Ticagrelor vs. clopidogrel in patients with acute coronary syndromes and diabetes: a substudy from the PLATelet inhibition and patient Outcomes (PLATO) trial Stefan Karl James, Dominick Joseph Angiolillo, Jan Hein Cornel et al. · European Heart Journal Open access 29 Aug 2010 450
34 Epilepsy in low‐grade gliomas: The impact on cognitive function and quality of life Martin Klein, Nadine H. J. Engelberts, Henk M. van der Ploeg et al. · Annals of Neurology Open access 19 Sep 2003 430
35 Premature ovarian failure: a systematic review on therapeutic interventions to restore ovarian function and achieve pregnancy YVONNE VAN KASTEREN · Human Reproduction Update ReviewOpen access Sep 1999 411
36 Supervised exercise therapy versus non-supervised exercise therapy for intermittent claudication Hugo JP Fokkenrood, Bianca L.W. Bendermacher, Gert Jan Lauret et al. · Cochrane Database of Systematic Reviews 23 Aug 2013 395
37 Final results of the Cervical Incompetence Prevention Randomized Cerclage Trial (CIPRACT): Therapeutic cerclage with bed rest versus bed rest alone Sietske M. Althuisius, Gustaaf Dekker, Pieter Hummel et al. · American Journal of Obstetrics and Gynecology Nov 2001 392
38 Randomised controlled trial comparing transfusion of leucocyte-depleted or buffy-coat-depleted blood in surgery for colorectal cancer Jos G. A. Houbiers, Anneke Brand, Leo M.G. van de Watering et al. · The Lancet Aug 1994 390
39 Antibiotic Treatment Strategies for Community-Acquired Pneumonia in Adults Douwe F. Postma, Cornelis H. van Werkhoven, Leontine J. R. van Elden et al. · New England Journal of Medicine Open access 2 Apr 2015 389
40 Bleeding complications with the P2Y12 receptor antagonists clopidogrel and ticagrelor in the PLATelet inhibition and patient Outcomes (PLATO) trial Richard C. Becker, Jean‐Pierre Bassand, Andrzej Budaj et al. · European Heart Journal Open access 16 Nov 2011 386
41 Effect of rivastigmine as an adjunct to usual care with haloperidol on duration of delirium and mortality in critically ill patients: a multicentre, double-blind, placebo-controlled randomised trial Maarten MJ van Eijk, Kit CB Roes, Marina L. H. Honing et al. · The Lancet Nov 2010 371
42 Endothelial Dysfunction, Inflammation, and Apoptosis in Diabetes Mellitus Inge A. M. van den Oever, Hennie G. Raterman, Mike T. Nurmohamed et al. · Mediators of Inflammation Open access 2010 369
43 Laparoscopic ileocaecal resection versus infliximab for terminal ileitis in Crohn's disease: a randomised controlled, open-label, multicentre trial Cyriel Y. Ponsioen et al. · ˜The œLancet. Gastroenterology & hepatology 31 Aug 2017 368
44 Improvement of left ventricular ejection fraction, heart failure symptoms and prognosis after revascularization in patients with chronic coronary artery disease and viable myocardium detected by dobutamine stress echocardiography Jeroen Joost Bax, Don Poldermans, Abdou Elhendy et al. · Journal of the American College of Cardiology Open access Jul 1999 363
45 Early versus On-Demand Nasoenteric Tube Feeding in Acute Pancreatitis Olaf J. Bakker et al. · New England Journal of Medicine Open access 20 Nov 2014 344
46 Effect of socket preservation therapies following tooth extraction in non-molar regions in humans: a systematic review J. M. A. G. Ten Heggeler, Dagmar Else Slot, G.A. van der Weijden · Clinical Oral Implants Research Review 22 Nov 2010 343
47 Functional Recovery After Acute Myocardial Infarction Robin Nijveldt, Aernout M. Beek, Alexander Hirsch et al. · Journal of the American College of Cardiology Open access Jul 2008 343
48 The Preventive Antibiotics in Stroke Study (PASS): a pragmatic randomised open-label masked endpoint clinical trial Willeke F. Westendorp et al. · The Lancet Open access 19 Jan 2015 339
49 Randomized clinical trial of observational versus antibiotic treatment for a first episode of CT-proven uncomplicated acute diverticulitis Lidewine Daniels et al. · British journal of surgery Open access 30 Sep 2016 329
50 Prognosis of coma after therapeutic hypothermia: A prospective cohort study Aline Bouwes, Jan M. Binnekade, Michael A. Kuiper et al. · Annals of Neurology 12 Sep 2011 328

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.