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Most cited papers from Medisch Spectrum Twente

Medisch Spectrum Twente

What are the most cited papers from Medisch Spectrum Twente?

The most cited paper from Medisch Spectrum Twente is "A novel assay for apoptosis Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V" (István Vermes, C. Haanen, Helga M. Steffens-nakken et al., 1995), with 5,471 citations. Next come "Genetics of rheumatoid arthritis contributes to biology and drug discovery" (2,501) and "A Comparison of Rate Control and Rhythm Control in Patients with Recurrent Persistent Atrial Fibrillation" (2,377).

Showing 50 of 61 papers. Every paper with more than 376 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 A novel assay for apoptosis Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V István Vermes, C. Haanen, Helga M. Steffens-nakken et al. · Journal of Immunological Methods Open access Jul 1995 5,471
2 Genetics of rheumatoid arthritis contributes to biology and drug discovery Yukinori Okada et al. · Nature Open access 24 Dec 2013 2,501
3 A Comparison of Rate Control and Rhythm Control in Patients with Recurrent Persistent Atrial Fibrillation Isabelle C. Van Gelder, Vincent E. Hagens, Hans A. Bosker et al. · New England Journal of Medicine Open access 5 Dec 2002 2,377
4 Surgery and postoperative radiotherapy versus surgery alone for patients with stage-1 endometrial carcinoma: multicentre randomised trial Carien L. Creutzberg, Wim LJ van Putten, Peter C.M. Koper et al. · The Lancet Apr 2000 1,786
5 A Step-up Approach or Open Necrosectomy for Necrotizing Pancreatitis Hjalmar C. van Santvoort et al. · New England Journal of Medicine Open access 21 Apr 2010 1,726
6 Vaginal brachytherapy versus pelvic external beam radiotherapy for patients with endometrial cancer of high-intermediate risk (PORTEC-2): an open-label, non-inferiority, randomised trial Remi A. Nout, VTHBM Smit, Hein Putter et al. · The Lancet Mar 2010 1,154
7 American Clinical Neurophysiology Society's Standardized Critical Care EEG Terminology: 2021 Version Lawrence J. Hirsch et al. · Journal of Clinical Neurophysiology Open access 2021 1,132
8 Randomised comparison of combined step-down prednisolone, methotrexate and sulphasalazine with sulphasalazine alone in early rheumatoid arthritis Maarten Boers, Arco C. Verhoeven, Harry M. Markusse et al. · The Lancet Open access Aug 1997 1,078
9 Preoperative Biliary Drainage for Cancer of the Head of the Pancreas Niels Anthony Van Der Gaag, Erik A. Rauws, Casper H.J. van Eijck et al. · New England Journal of Medicine Open access 13 Jan 2010 1,049
10 Improved Risk Assessment by Integrating Molecular and Clinicopathological Factors in Early-stage Endometrial Cancer—Combined Analysis of the PORTEC Cohorts Ellen Stelloo, Remi A. Nout, Elisabeth M. Osse et al. · Clinical Cancer Research 22 Mar 2016 872
11 Prevalence of comorbidities in rheumatoid arthritis and evaluation of their monitoring: results of an international, cross-sectional study (COMORA) Maxime Dougados et al. · Annals of the Rheumatic Diseases Open access 4 Oct 2013 871
12 Efficacy and safety of procalcitonin guidance in reducing the duration of antibiotic treatment in critically ill patients: a randomised, controlled, open-label trial Evelien de Jong et al. · The Lancet Infectious Diseases Open access 2 Mar 2016 847
13 Flow cytometry of apoptotic cell death István Vermes, C. Haanen, Chris P.M. Reutelingsperger · Journal of Immunological Methods Sep 2000 793
14 Subthalamic nucleus versus globus pallidus bilateral deep brain stimulation for advanced Parkinson's disease (NSTAPS study): a randomised controlled trial Vincent J.J. Odekerken, Teus van Laar, Michiel J. Staal et al. · The Lancet Neurology 15 Nov 2012 775
15 Acceptance- and mindfulness-based interventions for the treatment of chronic pain: a meta-analytic review Martine M. Veehof, Hester R. Trompetter, Ernst Thomas Bohlmeijer et al. · Cognitive Behaviour Therapy Open access 2 Jan 2016 762
16 A Conservative and Minimally Invasive Approach to Necrotizing Pancreatitis Improves Outcome Hjalmar C. van Santvoort et al. · Gastroenterology Open access 10 Jul 2011 748
17 Endoscopic or Surgical Step-Up Approach for Infected Necrotising Pancreatitis: A Multicentre Randomised Trial Sandra van Brunschot et al. · The Lancet Open access 3 Nov 2017 743
18 Procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections Philipp Schüetz et al. · Cochrane Database of Systematic Reviews Open access 12 Oct 2017 657
19 Stroke genetics informs drug discovery and risk prediction across ancestries Aniket Mishra et al. · Nature Open access592 authors 30 Sep 2022 637
20 Electrospinning of collagen and elastin for tissue engineering applications Laura Buttafoco, N.G. Kolkman, P. Engbers‐Buijtenhuijs et al. · Biomaterials 20 Aug 2005 629
21 Minimally Invasive Versus Open Distal Pancreatectomy (LEOPARD) Thijs de Rooij et al. · Annals of Surgery Open access 3 Aug 2018 625
22 COBRA combination therapy in patients with early rheumatoid arthritis: Long‐term structural benefits of a brief intervention Robert Landewé, Maarten Boers, Arco C. Verhoeven et al. · Arthritis & Rheumatism Open access Feb 2002 614
23 Laparoscopic versus open pancreatoduodenectomy for pancreatic or periampullary tumours (LEOPARD-2): a multicentre, patient-blinded, randomised controlled phase 2/3 trial Jony van Hilst et al. · ˜The œLancet. Gastroenterology & hepatology Open access115 authors 27 Jan 2019 611
24 Diagnostic Accuracy of Fast Computational Approaches to Derive Fractional Flow Reserve From Diagnostic Coronary Angiography Shengxian Tu, Jelmer Sybren Westra, Junqing Yang et al. · JACC: Cardiovascular Interventions Open access Oct 2016 604
25 Self management for patients with chronic obstructive pulmonary disease Marlies Zwerink, Marjolein G J Brusse-Keizer, Paul DLPM van der Valk et al. · Cochrane Database of Systematic Reviews Open access 24 Mar 2014 581
26 Tumor-Infiltrating Lymphocyte Therapy or Ipilimumab in Advanced Melanoma Maartje W. Rohaan et al. · New England Journal of Medicine Open access 7 Dec 2022 577
27 Lung cancer LDCT screening and mortality reduction — evidence, pitfalls and future perspectives Matthijs Oudkerk, Shiyuan Liu, Marjolein A. Heuvelmans et al. · Nature Reviews Clinical Oncology ReviewOpen access 12 Oct 2020 556
28 Coronary Angiography after Cardiac Arrest without ST-Segment Elevation Jorrit S. Lemkes et al. · New England Journal of Medicine Open access 18 Mar 2019 548
29 36th International Symposium on Intensive Care and Emergency Medicine R. M. Bateman et al. · Critical Care Open access2,440 authors Apr 2016 531
30 Obesity affects spontaneous pregnancy chances in subfertile, ovulatory women Jan Willem van der Steeg, Pieternel Steures, Marinus J.C. Eijkemans et al. · Human Reproduction Open access 12 Dec 2007 519
31 Effect of long-acting nifedipine on mortality and cardiovascular morbidity in patients with stable angina requiring treatment (ACTION trial): randomised controlled trial Philip Alexander Poole-Wilson et al. · The Lancet Sep 2004 518
32 Prehospital initiation of tirofiban in patients with ST-elevation myocardial infarction undergoing primary angioplasty (On-TIME 2): a multicentre, double-blind, randomised controlled trial Arnoud W.J. van ’t Hof, Jurriën M. ten Berg, Ton A.A.C.M. Heestermans et al. · The Lancet Aug 2008 513
33 Effects of the Direct Lipoprotein-Associated Phospholipase A 2 Inhibitor Darapladib on Human Coronary Atherosclerotic Plaque Patrick W.J.C. Serruys et al. · Circulation Open access 3 Sep 2008 505
34 Effect of procalcitonin-guided antibiotic treatment on mortality in acute respiratory infections: a patient level meta-analysis Philipp Schüetz et al. · The Lancet Infectious Diseases Open access 14 Oct 2017 490
35 Safety of pulsed field ablation in more than 17,000 patients with atrial fibrillation in the MANIFEST-17K study Emmanuel Ekanem et al. · Nature Medicine Open access139 authors Jul 2024 484
36 Colonic stenting versus emergency surgery for acute left-sided malignant colonic obstruction: a multicentre randomised trial Jeanin Elise van Hooft, Willem Adrianus Bemelman, Bas Oldenburg et al. · The Lancet Oncology Open access 16 Mar 2011 473
37 Cardiovascular disease in patients with rheumatoid arthritis: results from the QUEST-RA study Antonio Naranjo et al. · Arthritis Research & Therapy Open access 6 Mar 2008 473
38 Low skeletal muscle area is a risk factor for mortality in mechanically ventilated critically ill patients Peter J.M. Weijs, Wilhelmus G. P. M. Looijaard, Ingeborg M. Dekker et al. · Critical Care Open access 13 Jan 2014 463
39 Substantial lymph-vascular space invasion (LVSI) is a significant risk factor for recurrence in endometrial cancer – A pooled analysis of PORTEC 1 and 2 trials Tjalling Bosse, Elke E.M. Peters, Carien L. Creutzberg et al. · European Journal of Cancer Open access 6 Jun 2015 453
40 High Prognostic Impact of Flow Cytometric Minimal Residual Disease Detection in Acute Myeloid Leukemia: Data From the HOVON/SAKK AML 42A Study Monique Terwijn et al. · Journal of Clinical Oncology Open access 24 Sep 2013 452
41 Aspirin plus Heparin or Aspirin Alone in Women with Recurrent Miscarriage Stef P. Kaandorp, Mariëtte Goddijn, Joris van der Post et al. · New England Journal of Medicine 25 Mar 2010 452
42 Chemotherapy plus Involved-Field Radiation in Early-Stage Hodgkin's Disease Christophe Fermé et al. · New England Journal of Medicine Open access 7 Nov 2007 448
43 Effect of Ranolazine, an Antianginal Agent With Novel Electrophysiological Properties, on the Incidence of Arrhythmias in Patients With Non–ST-Segment–Elevation Acute Coronary Syndrome Benjamin M. Scirica, David A. Morrow, Hanoch Hod et al. · Circulation Open access 6 Sep 2007 445
44 10 year survival after breast-conserving surgery plus radiotherapy compared with mastectomy in early breast cancer in the Netherlands: a population-based study Marissa Corine van Maaren, Linda de Munck, Geertruida H. de Bock et al. · The Lancet Oncology Open access 24 Jun 2016 441
45 Risk factors for septic arthritis in patients with joint disease Carola J. E. Kaandorp, Dirkjan van Schaardenburg, Pieta Krijnen et al. · Arthritis & Rheumatism Open access Dec 1995 440
46 Mutations in the Transcription Factor Gene SOX18 Underlie Recessive and Dominant Forms of Hypotrichosis-Lymphedema-Telangiectasia Alexandre Irrthum, Koenraad Devriendt, David A. Chitayat et al. · The American Journal of Human Genetics Open access Jun 2003 432
47 Minimum clinically important improvement and patient acceptable symptom state in pain and function in rheumatoid arthritis, ankylosing spondylitis, chronic back pain, hand osteoarthritis, and hip and knee osteoarthritis: Results from a prospective multinational study Florence Tubach, Philippe Ravaud, Emilio Martín-Mola et al. · Arthritis Care & Research Open access 6 Jun 2012 429
48 Aspirin with or without Clopidogrel after Transcatheter Aortic-Valve Implantation Jorn Brouwer et al. · New England Journal of Medicine Open access 30 Aug 2020 423
49 Stent-Related Adverse Events >1 Year After Percutaneous Coronary Intervention Mahesh V. Madhavan, Ajay Jayant Kirtane, Björn Redfors et al. · Journal of the American College of Cardiology Open access Feb 2020 421
50 Alternative Fistula Risk Score for Pancreatoduodenectomy (a-FRS) Timothy H. Mungroop et al. · Annals of Surgery Open access 13 Dec 2017 419

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.