Most cited papers from Meikai University

Meikai University

What are the most cited papers from Meikai University?

The most cited paper from Meikai University is "Commitment and Differentiation of Osteoclast Precursor Cells by the Sequential Expression of C-Fms and Receptor Activator of Nuclear Factor κb (Rank) Receptors" (Fumio Arai, Takeshi Ken Miyamoto, Osamu Ohneda et al., 1999), with 700 citations. Next come "PGC7/Stella protects against DNA demethylation in early embryogenesis" (586) and "Estrogen Inhibits Bone Resorption by Directly Inducing Apoptosis of the Bone-resorbing Osteoclasts" (540).

Published TypeFieldAccessCitations

Showing 50 of 60 papers. Every paper with more than 116 citations is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	Commitment and Differentiation of Osteoclast Precursor Cells by the Sequential Expression of C-Fms and Receptor Activator of Nuclear Factor κb (Rank) Receptors Fumio Arai, Takeshi Ken Miyamoto, Osamu Ohneda et al. · The Journal of Experimental Medicine Open access	20 Dec 1999	700
2	PGC7/Stella protects against DNA demethylation in early embryogenesis Toshinobu Nakamura, Yoshikazu Arai, Hiroki Umehara et al. · Nature Cell Biology	3 Dec 2006	586
3	Estrogen Inhibits Bone Resorption by Directly Inducing Apoptosis of the Bone-resorbing Osteoclasts Takashi Kameda, Hiroshi Mano, Tatsuhisa Yuasa et al. · The Journal of Experimental Medicine Open access	18 Aug 1997	540
4	Large Scale Gene Expression Analysis of Osteoclastogenesisin Vitro and Elucidation of NFAT2 as a Key Regulator Norihiro Ishida, Kôji Hayashi, Mitsuhiro Hoshijima et al. · Journal of Biological Chemistry Open access	Oct 2002	380
5	Molecular Cloning of Human cDNA for Cathepsin K: Novel Cysteine Proteinase Predominantly Expressed in Bone Tetsuya Inaoka, Graeme Bilbe, Osamu Ishibashi et al. · Biochemical and Biophysical Research Communications	1995	357
6	Direct stimulation of osteoclastic bone resorption by bone morphogenetic protein (BMP)-2 and expression of BMP receptors in mature osteoclasts H Kaneko, Toshiya Arakawa, Hiroshi Mano et al. · Bone	Oct 2000	349
7	Vascular endothelial growth factor (VEGF) directly enhances osteoclastic bone resorption and survival of mature osteoclasts Mari Nakagawa, Toshio Kaneda, Toshiya Arakawa et al. · FEBS Letters Open access	9 May 2000	349
8	Molecular cloning of a possible cysteine proteinase predominantly expressed in osteoclasts. K. Tezuka, YASUYUKI TEZUKA, Atsushi Maejima et al. · Journal of Biological Chemistry Open access	1994	339
9	Meflin-Positive Cancer-Associated Fibroblasts Inhibit Pancreatic Carcinogenesis Yasuyuki Mizutani et al. · Cancer Research Open access	22 Aug 2019	335
10	Triterpene Alcohol and Sterol Ferulates from Rice Bran and Their Anti-inflammatory Effects Toshihiro Akihisa, Ken Yasukawa, Miho Yamaura et al. · Journal of Agricultural and Food Chemistry	26 May 2000	314
11	Excessive mechanical loading promotes osteoarthritis through the gremlin-1–NF-κB pathway Song Ho Chang, Daisuke Mori, Hiroshi Kobayashi et al. · Nature Communications Open access	29 Mar 2019	300
12	Production of bioactive triterpenes by Eriobotrya japonica calli Shoko Taniguchi, Yoko Imayoshi, Eri Kobayashi et al. · Phytochemistry	Feb 2002	294
13	Antioxidant and prooxidant action of eugenol-related compounds and their cytotoxicity Seiichiro Fujisawa, Toshiko Atsumi, Yoshinori Kadoma et al. · Toxicology	Aug 2002	287
14	Mandibular onlay grafting using prefabricated bone grafts with primary implant placement: an experimental study in minipigs. T Miyata, Y Kobayashi, H Araki et al. · PubMed	29 Jun 1998	249
15	Anatomy and Histology of Rodent and Human Major Salivary Glands—Overview of the Japan Salivary Gland Society-Sponsored Workshop— Osamu Amano, Kenichi Mizobe, Yasuhiko Bando et al. · ACTA HISTOCHEMICA ET CYTOCHEMICA Open access	2012	247
16	Insulin-like growth factor-I supports formation and activation of osteoclasts. Hiroshi Mochizuki, Yoshiyuki Hakeda, N Wakatsuki et al. · Endocrinology	Sep 1992	245
17	Cytotoxicity, ROS-generation activity and radical-scavenging activity of curcumin and related compounds. Seiichiro Fujisawa, Toshiko Atsumi, Mariko Ishihara et al. · PubMed	19 Jul 2004	234
18	Stimulatory effect of bone morphogenetic protein-2 on osteoclast-like cell formation and bone-resorbing activity Masanori Kanatani, Toshitsugu Sugimoto, Hiroshi Kaji et al. · Journal of Bone and Mineral Research	Nov 1995	226
19	Calcium-Sensing Receptor in Mature Osteoclasts, Which Are Bone Resorbing Cells Takashi Kameda, Hiroshi Mano, Yoshiji Yamada et al. · Biochemical and Biophysical Research Communications	Apr 1998	219
20	Absorption and urinary excretion of procyanidin B2 [epicatechin-(4β-8)-epicatechin] in rats Seigo Baba, Naomi Osakabe, Midori Natsume et al. · Free Radical Biology and Medicine	Jul 2002	219
21	Identification of the membrane-type matrix metalloproteinase MT1-MMP in osteoclasts Takuya Sato, Maria del Carmen Ovejero, Hou Peng et al. · Journal of Cell Science	Mar 1997	213
22	Identification of osteopontin in isolated rabbit osteoclasts Ken-ichi Tezuka, Takuya Sato, Hiroshi Kamioka et al. · Biochemical and Biophysical Research Communications	Jul 1992	212
23	The potential role of interleukin‐17 in the immunopathology of periodontal disease Keiso Takahashi, Takashi Azuma, Hitoshi Motohira et al. · Journal Of Clinical Periodontology	29 Mar 2005	211
24	3,5-Dibenzoyl-1,4-dihydropyridines: Synthesis and MDR Reversal in Tumor Cells Masami Kawase, Anamik K. Shah, Harsukh Gaveriya et al. · Bioorganic & Medicinal Chemistry	Apr 2002	203
25	Generation of osteoclasts from isolated hematopoietic progenitor cells Noriyoshi Kurihara, Toshio Suda, Yasusada Miura et al. · Blood Open access	Sep 1989	202
26	ACE2: The key Molecule for Understanding the Pathophysiology of Severe and Critical Conditions of COVID-19: Demon or Angel? Li Xiao, Hiroshi Sakagami, Nobuhiko Miwa · Viruses Open access	28 Apr 2020	194
27	Keratocystic odontogenic tumor: a retrospective study of 183 cases Patricia González‐Alva, Akio Tanaka, Yuka Oku et al. · Journal of Oral Science Open access	2008	189
28	Smelling lavender and rosemary increases free radical scavenging activity and decreases cortisol level in saliva Toshiko Atsumi, Keiichi Tonosaki · Psychiatry Research	Feb 2007	188
29	Mechanical, antibacterial and bond strength properties of nano-titanium-enriched glass ionomer cement René García‐Contreras, Rogelio José Scougall‐Vilchis, Rosalía Contreras‐Bulnes et al. · Journal of Applied Oral Science Open access	Jun 2015	187
30	Cytotoxic Flavonoids with Isoprenoid Groups from Morus mongolica Yaqin Shi, Toshio Fukai, Hiroshi Sakagami et al. · Journal of Natural Products	4 Jan 2001	167
31	Identification of matrix metalloproteinase 9 in rabbit osteoclasts. K. Tezuka, Keita Nemoto, YASUYUKI TEZUKA et al. · Journal of Biological Chemistry Open access	May 1994	166
32	Cerebrosides A and C, Sphingolipid Elicitors of Hypersensitive Cell Death and Phytoalexin Accumulation in Rice Plants Jinichiro Koga, Toyozo Yamauchi, Masaru Shimura et al. · Journal of Biological Chemistry Open access	Nov 1998	165
33	Kinetics of radical-scavenging activity of hesperetin and hesperidin and their inhibitory activity on COX-2 expression. Atsusi Hirata, Yukio Murakami, Masao Shoji et al. · PubMed	13 Oct 2005	163
34	Nerve distribution to the human knee joint: anatomical and immunohistochemical study Yasusuke Hirasawa, Seiichiro Okajima, Masaharu Ohta et al. · International Orthopaedics Open access	10 Mar 2000	162
35	Interleukin-1 stimulates cytokines, prostaglandin E2 and matrix metalloproteinase-1 production via activation of MAPK/AP-1 and NF-κB in human gingival fibroblasts Yoshihiro Kida, Makoto Kobayashi, Takao Suzuki et al. · Cytokine	10 Dec 2004	155
36	Polyphenols from Eriobotrya japonica and Their Cytotoxicity against Human Oral Tumor Cell Lines. Hideyuki Ito, Eri Kobayashi, Yoshie Takamatsu et al. · Chemical and Pharmaceutical Bulletin Open access	2000	151
37	Fluid Shear Stress-induced Cyclooxygenase-2 Expression Is Mediated by C/EBP β, cAMP-response Element-binding Protein, and AP-1 in Osteoblastic MC3T3-E1 Cells Aichi Ogasawara, Toshiya Arakawa, Toshio Kaneda et al. · Journal of Biological Chemistry Open access	Mar 2001	150
38	Cathepsin K Antisense Oligodeoxynucleotide Inhibits Osteoclastic Bone Resorption Takashi Inui, Osamu Ishibashi, Tetsuya Inaoka et al. · Journal of Biological Chemistry Open access	Mar 1997	150
39	New anticancer drug candidates sulfonamides as selective hCA IX or hCA XII inhibitors Halise İnci Gül, Cem Yamalı, Hiroshi Sakagami et al. · Bioorganic Chemistry Open access	16 Jan 2018	147
40	A comparative study of the antioxidant/prooxidant activities of eugenol and isoeugenol with various concentrations and oxidation conditions T Atsumi, Sechiro Fujisawa, Keiichi Tonosaki · Toxicology in Vitro	20 Jun 2005	147
41	Synthesis and bioactivities of pyrazoline benzensulfonamides as carbonic anhydrase and acetylcholinesterase inhibitors with low cytotoxicity Dilan Özmen Özgün, Halise İnci Gül, Cem Yamalı et al. · Bioorganic Chemistry	20 Dec 2018	143
42	Vitamin K2Inhibits Osteoclastic Bone Resorption by Inducing Osteoclast Apoptosis Takashi Kameda, Koshi Miyazawa, Yoshihisa Mori et al. · Biochemical and Biophysical Research Communications	Mar 1996	140
43	Radical scavenging activity and cytotoxicity of ferulic acid. Takako Ogiwara, Kazue Satoh, Yoshinori Kadoma et al. · PubMed	20 Feb 2003	137
44	Synthesis and bioactivity studies on new 4-(3-(4-Substitutedphenyl)-3a,4-dihydro-3H-indeno[1,2-c]pyrazol-2-yl) benzenesulfonamides Halise İnci Gül, Mehtap Tugrak, Hiroshi Sakagami et al. · Journal of Enzyme Inhibition and Medicinal Chemistry Open access	30 Mar 2016	134
45	Clinical application of removable partial dentures using thermoplastic resin—Part I: Definition and indication of non-metal clasp dentures Kenji Fueki et al. · Journal of Prosthodontic Research Open access	2014	134
46	Preliminary evaluation of antinephritis and radical scavenging activities of glabridin from Glycyrrhiza glabra Toshio Fukai, Kazue Satoh, Taro Nomura et al. · Fitoterapia	12 Aug 2003	133
47	Computer-Mediated Relationship Development: A Cross-Cultural Comparison Young-ok Yum, Kazuya Hara · Journal of Computer-Mediated Communication Open access	Nov 2005	132
48	The periodontal pathogen Porphyromonas gingivalis induces the Epstein–Barr virus lytic switch transactivator ZEBRA by histone modification Kenichi Imai, Harumi Inoue, Muneaki Tamura et al. · Biochimie	11 Dec 2011	132
49	Cytotoxicity and apoptosis induction by butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT). Masatoshi Saito, Hiroshi Sakagami, Seiichiro Fujisawa · PubMed	Apr 2004	131
50	Traits and genotypes may predict the successful training of drug detection dogs Masami Maejima, Miho Inoue‐Murayama, Keiichi Tonosaki et al. · Applied Animal Behaviour Science	14 Nov 2006	131

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.