| 1 |
Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016
Andrew Rhodes et al. · Intensive Care Medicine
Open access |
18 Jan 2017 |
6,868 |
| 2 |
Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008
R. Phillip Dellinger et al. · Intensive Care Medicine
Open access |
3 Dec 2007 |
4,947 |
| 3 |
Recommendations for evaluation of the severity of native valvular regurgitation with two-dimensional and doppler echocardiography
William A. Zoghbi, Maurice L. Enriquez-Sarano, Elyse Foster et al. · Journal of the American Society of Echocardiography
Open access |
30 Jun 2003 |
4,077 |
| 4 |
Recommendations for Noninvasive Evaluation of Native Valvular Regurgitation
William A. Zoghbi, David H Adams, Robert O. Bonow et al. · Journal of the American Society of Echocardiography
|
14 Mar 2017 |
3,570 |
| 5 |
Ranibizumab versus Verteporfin for Neovascular Age-Related Macular Degeneration
David M. Brown, Peter K. Kaiser, Mark Michels et al. · New England Journal of Medicine
|
4 Oct 2006 |
3,535 |
| 6 |
Doppler Tissue Imaging: A Noninvasive Technique for Evaluation of Left Ventricular Relaxation and Estimation of Filling Pressures
Sherif F. Nagueh, Katherine J. Middleton, Helen A. Kopelen et al. · Journal of the American College of Cardiology
Open access |
Nov 1997 |
3,041 |
| 7 |
Effects of COVID-19 on College Students’ Mental Health in the United States: Interview Survey Study
Changwon Son, Sudeep Hegde, Alec Smith et al. · Journal of Medical Internet Research
Open access |
15 Aug 2020 |
2,848 |
| 8 |
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1
Daniel J. Klionsky et al. · Autophagy
Open access2,930 authors |
2 Jan 2021 |
2,743 |
| 9 |
The International Scientific Association of Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of postbiotics
Seppo Salminen, María Carmen Collado, Akihito Endo et al. · Nature Reviews Gastroenterology & Hepatology
ReviewOpen access |
4 May 2021 |
2,385 |
| 10 |
Worldwide Prevalence and Burden of Functional Gastrointestinal Disorders, Results of Rome Foundation Global Study
Ami D. Sperber et al. · Gastroenterology
Open access |
12 Apr 2020 |
2,280 |
| 11 |
Targeting NF-κB pathway for the therapy of diseases: mechanism and clinical study
Hui Yu, Liangbin Lin, Zhiqiang Zhang et al. · Signal Transduction and Targeted Therapy
Open access |
21 Sep 2020 |
2,178 |
| 12 |
Echocardiographic Assessment of Valve Stenosis: EAE/ASE Recommendations for Clinical Practice
Helmut Baumgartner, Judy W. S. Hung, Javier Bermejo et al. · Journal of the American Society of Echocardiography
Open access |
2009 |
2,147 |
| 13 |
ACC/AHA/ESC 2006 Guidelines for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death
Douglas Peter Zipes et al. · Journal of the American College of Cardiology
Open access |
31 Aug 2006 |
1,975 |
| 14 |
Stenting versus Aggressive Medical Therapy for Intracranial Arterial Stenosis
Marc I. Chimowitz et al. · New England Journal of Medicine
Open access |
7 Sep 2011 |
1,903 |
| 15 |
MeCP2, a Key Contributor to Neurological Disease, Activates and Represses Transcription
Maria H. Chahrour, Sung Yun Jung, Chad A. Shaw et al. · Science
Open access |
29 May 2008 |
1,859 |
| 16 |
Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance
Kari R. Fischer, Anna Durrans, Sharrell Lee et al. · Nature
Open access |
10 Nov 2015 |
1,830 |
| 17 |
Stroke-Associated Pneumonia: Major Advances and Obstacles
Yousef Hannawi, Bashar Hannawi, Chethan P. Venkatasubba Rao et al. · Cerebrovascular Diseases
Open access |
2013 |
1,670 |
| 18 |
Multidetector Computed Tomography for Acute Pulmonary Embolism
Paul D. Stein, Sarah E. Fowler, Lawrence R. Goodman et al. · New England Journal of Medicine
Open access |
31 May 2006 |
1,664 |
| 19 |
Ranibizumab for Diabetic Macular Edema
Quan Dong Nguyen, David M. Brown, Dennis M. Marcus et al. · Ophthalmology
|
11 Feb 2012 |
1,625 |
| 20 |
Hyponatremia
Horacio J. Adrogué, Nicolaos E. Madias · New England Journal of Medicine
|
25 May 2000 |
1,597 |
| 21 |
A clinicopathologic analysis of adriamycin cardiotoxicity
Edward A. Lefrak, Jan V Pitha, Sidney Rosenheim et al. · Cancer
|
Aug 1973 |
1,566 |
| 22 |
Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: a randomised placebocontrolled study
Richard N. Channick, Gérald Simonneau, Olivier Sitbon et al. · The Lancet
|
Oct 2001 |
1,537 |
| 23 |
Investigating Mental Health of US College Students During the COVID-19 Pandemic: Cross-Sectional Survey Study
Xiaomei Wang, Sudeep Hegde, Changwon Son et al. · Journal of Medical Internet Research
Open access |
7 Sep 2020 |
1,486 |
| 24 |
Comprehensive Genomic Analysis Identifies Novel Subtypes and Targets of Triple-Negative Breast Cancer
Matthew D. Burstein, Anna I. Tsimelzon, Graham M. Poage et al. · Clinical Cancer Research
Open access |
11 Sep 2014 |
1,430 |
| 25 |
A critical review of recombinant human bone morphogenetic protein-2 trials in spinal surgery: emerging safety concerns and lessons learned
Eugene J. Carragee, Eric L. Hurwitz, Bradley Kenneth Weiner · The Spine Journal
|
Jun 2011 |
1,410 |
| 26 |
Ranibizumab versus Verteporfin Photodynamic Therapy for Neovascular Age-Related Macular Degeneration: Two-Year Results of the ANCHOR Study
David M. Brown, Mark Michels, Peter K. Kaiser et al. · Ophthalmology
|
31 Dec 2008 |
1,323 |
| 27 |
A Fully Magnetically Levitated Left Ventricular Assist Device — Final Report
Mandeep R. Mehra et al. · New England Journal of Medicine
Open access |
17 Mar 2019 |
1,314 |
| 28 |
A distinct “side population” of cells with high drug efflux capacity in human tumor cells
Charlotte Hirschmann-Jax, Angela E. Foster, Gerald Georg Wulf et al. · Proceedings of the National Academy of Sciences
Open access |
20 Sep 2004 |
1,279 |
| 29 |
Bronchiolitis obliterans syndrome 2001: an update of the diagnostic criteria
Marc Estenne, JANET R. MAURER, Annette Boehler et al. · The Journal of Heart and Lung Transplantation
Open access |
Mar 2002 |
1,278 |
| 30 |
Current and Evolving Echocardiographic Techniques for the Quantitative Evaluation of Cardiac Mechanics: ASE/EAE Consensus Statement on Methodology and Indications
Victor Mor‐Avi, Roberto Miguel Lang, Luigi Paolo Badano et al. · Journal of the American Society of Echocardiography
Open access |
20 Feb 2011 |
1,267 |
| 31 |
A Preoperative Nomogram for Disease Recurrence Following Radical Prostatectomy for Prostate Cancer
Michael W. Kattan, James Andrew Eastham, Alan M. F. Stapleton et al. · JNCI Journal of the National Cancer Institute
|
20 May 1998 |
1,262 |
| 32 |
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma
Roger Stupp et al. · JAMA
Open access |
15 Dec 2015 |
1,256 |
| 33 |
Effect of epidural stimulation of the lumbosacral spinal cord on voluntary movement, standing, and assisted stepping after motor complete paraplegia: a case study
Susan J. Harkema, Yury Gerasimenko, Jonathan E. Hodes et al. · The Lancet
Open access |
23 May 2011 |
1,244 |
| 34 |
Hepatocellular carcinoma: a review
Julius Balogh, David W. Victor, Emad H. Asham et al. · Journal of Hepatocellular Carcinoma
Open access |
Oct 2016 |
1,225 |
| 35 |
Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma
Martin Pulé, Barbara Savoldo, Gary D. Myers et al. · Nature Medicine
Open access |
Nov 2008 |
1,200 |
| 36 |
American Association of Clinical Endocrinologists/American College of Endocrinology Clinical Practice Guidelines for the Diagnosis and Treatment of Postmenopausal Osteoporosis—2020 Update
Pauline M. Camacho, Steven M. Petak, Neil Binkley et al. · Endocrine Practice
|
May 2020 |
1,167 |
| 37 |
Ranibizumab for Macular Edema following Central Retinal Vein Occlusion
David M. Brown, Peter A. Campochiaro, Rishi P. Singh et al. · Ophthalmology
|
10 Apr 2010 |
1,160 |
| 38 |
American Association of Clinical Endocrinologists and American College of Endocrinology Clinical Practice Guidelines for the Diagnosis and Treatment of Postmenopausal Osteoporosis — 2016--Executive Summary
Pauline M. Camacho, Steven M. Petak, Neil Binkley et al. · Endocrine Practice
|
2016 |
1,147 |
| 39 |
Cardiac Troponin T Levels for Risk Stratification in Acute Myocardial Ischemia
Erik Magnus Ohman, Paul W. Armstrong, Robert H. Christenson et al. · New England Journal of Medicine
Open access |
31 Oct 1996 |
1,133 |
| 40 |
Caring for Critically Ill Patients with the ABCDEF Bundle: Results of the ICU Liberation Collaborative in Over 15,000 Adults
Brenda Truman Pun et al. · Critical Care Medicine
Open access |
18 Oct 2018 |
1,110 |
| 41 |
Current and Evolving Echocardiographic Techniques for the Quantitative Evaluation of Cardiac Mechanics: ASE/EAE Consensus Statement on Methodology and Indications Endorsed by the Japanese Society of Echocardiography
Victor Mor‐Avi, Roberto Miguel Lang, Luigi Paolo Badano et al. · European Journal of Echocardiography
Open access |
Mar 2011 |
1,093 |
| 42 |
Comparative Dose Efficacy Study of Atorvastatin Versus Simvastatin, Pravastatin, Lovastatin, and Fluvastatin in Patients With Hypercholesterolemia (The CURVES Study) fn1fn1This study was supported by Parke-Davis, Division of Warner Lambert Company, Morris Plains, New Jersey. Manuscript received August 20, 1997; revised manuscript received and accepted November 24, 1997.
Peter J.H. Jones, Stephanie D. Kafonek, Irene Laurora et al. · The American Journal of Cardiology
|
Mar 1998 |
1,079 |
| 43 |
Closure or Medical Therapy for Cryptogenic Stroke with Patent Foramen Ovale
Anthony J. Furlan, Mark Reisman, Joseph M. Massaro et al. · New England Journal of Medicine
|
14 Mar 2012 |
1,067 |
| 44 |
Transcatheter Aortic Valve Replacement Using a Self-Expanding Bioprosthesis in Patients With Severe Aortic Stenosis at Extreme Risk for Surgery
Jeffrey J. Popma et al. · Journal of the American College of Cardiology
Open access |
21 Mar 2014 |
1,050 |
| 45 |
CD28 costimulation improves expansion and persistence of chimeric antigen receptor–modified T cells in lymphoma patients
Barbara Savoldo, Carlos Almeida Ramos, Enli Liu et al. · Journal of Clinical Investigation
Open access |
25 Apr 2011 |
1,029 |
| 46 |
Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)
Andrea Cossarizza et al. · European Journal of Immunology
Open access436 authors |
Oct 2019 |
1,014 |
| 47 |
Irritable bowel syndrome
Paul Enck, Qasim Aziz, Giovanni Barbara et al. · Nature Reviews Disease Primers
ReviewOpen access |
24 Mar 2016 |
1,011 |
| 48 |
Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways
Elizabeth T. Cirulli et al. · Science
Open access |
21 Feb 2015 |
1,002 |
| 49 |
Updated Molecular Testing Guideline for the Selection of Lung Cancer Patients for Treatment With Targeted Tyrosine Kinase Inhibitors: Guideline From the College of American Pathologists, the International Association for the Study of Lung Cancer, and the Association for Molecular Pathology
Neal Ian Lindeman et al. · Archives of Pathology & Laboratory Medicine
Open access |
22 Jan 2018 |
953 |
| 50 |
The role of TGF-β signaling in myocardial infarction and cardiac remodeling
Maro Bujak, Nikolaos G. Frangogiannis · Cardiovascular Research
Open access |
10 Oct 2006 |
934 |