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Most cited papers from Mirus Bio (United States)

What are the most cited papers from Mirus Bio (United States)?

The most cited paper from Mirus Bio (United States) is "Program DYNAFIT for the Analysis of Enzyme Kinetic Data: Application to HIV Proteinase" (Petr Kuzmič, 1996), with 1,521 citations. Next come "Dynamic PolyConjugates for targeted in vivo delivery of siRNA to hepatocytes" (680) and "Efficient delivery of siRNA for inhibition of gene expression in postnatal mice" (552).

Showing 50 of 61 papers. Every paper with more than 19 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Program DYNAFIT for the Analysis of Enzyme Kinetic Data: Application to HIV Proteinase Petr Kuzmič · Analytical Biochemistry Jun 1996 1,521
2 Dynamic PolyConjugates for targeted in vivo delivery of siRNA to hepatocytes David B. Rozema, David Levering Lewis, Darren H. Wakefield et al. · Proceedings of the National Academy of Sciences Open access 24 Jul 2007 680
3 Efficient delivery of siRNA for inhibition of gene expression in postnatal mice David Levering Lewis, James E. Hagstrom, Aaron G. Loomis et al. · Nature Genetics 29 Jul 2002 552
4 Progress and prospects: naked DNA gene transfer and therapy Hans Herweijer, Jon A. Wolff · Gene Therapy Mar 2003 407
5 Reengineering a receptor footprint of adeno-associated virus enables selective and systemic gene transfer to muscle Aravind Asokan, Julia C Conway, Jana L. Phillips et al. · Nature Biotechnology Open access 27 Dec 2009 271
6 True Marc Dellian, Fan Yuan, V.S. Trubetskoy et al. · British Journal of Cancer Open access 2000 222
7 Hypothesis: naked plasmid DNA is taken up by cellsin vivo by a receptor-mediated process Vladimir G. Budker, Tatayana Budker, Guofeng Zhang et al. · The Journal of Gene Medicine Mar 2000 210
8 A Facile Nonviral Method for Delivering Genes and siRNAs to Skeletal Muscle of Mammalian Limbs James E. Hagstrom, Julia O Hegge, Guofeng Zhang et al. · Molecular Therapy Open access 22 Jun 2004 193
9 Gene therapy progress and prospects: Hydrodynamic gene delivery Hans Herweijer, Jon A. Wolff · Gene Therapy 30 Nov 2006 189
10 Breaking the Bonds: Non-viral Vectors Become Chemically Dynamic Jon A. Wolff, David B. Rozema · Molecular Therapy Open access 23 Oct 2007 164
11 Endosomolysis by Masking of a Membrane-Active Agent (EMMA) for Cytoplasmic Release of Macromolecules David B. Rozema, Kirk Ekena, David Levering Lewis et al. · Bioconjugate Chemistry 19 Dec 2002 162
12 Recharging cationic DNA complexes with highly charged polyanions for in vitro and in vivo gene delivery V.S. Trubetskoy, So C. Wong, Vladimir M. Subbotin et al. · Gene Therapy 23 Jan 2003 161
13 Polymeric micelles as carriers of diagnostic agents V.S. Trubetskoy · Advanced Drug Delivery Reviews Review 5 Apr 1999 147
14 Rational design and in vitro and in vivo delivery of Dicer substrate siRNA Mohammed Amarzguioui, Patric S. Lundberg, Edouard M. Cantin et al. · Nature Protocols 27 Jun 2006 132
15 Transcriptional and phenotypic comparisons of Ppara knockout and siRNA knockdown mice Angus T. De Souza, Xudong Dai, Andrew G Spencer et al. · Nucleic Acids Research Open access 31 Aug 2006 115
16 Alternative inclusion of fibroblast growth factor receptor 2 exon IIIc in Dunning prostate tumors reveals unexpected epithelial mesenchymal plasticity Sebastian Oltean, Brian S. Sorg, Todd R. Albrecht et al. · Proceedings of the National Academy of Sciences 8 Sep 2006 115
17 Porcine partial liver transplantation: A novel model of the “small-for-size” liver graft Dympna M. Kelly, Jake A. Demetris, John J. Fung et al. · Liver Transplantation Open access 31 Jan 2004 112
18 Recovery of the Endogenous β Cell Function in the NOD Model of Autoimmune Diabetes Tatiana D. Zorina, Vladimir M. Subbotin, Suzanne Bertera et al. · Stem Cells Jul 2003 110
19 Mechanism of plasmid delivery by hydrodynamic tail vein injection. I. Hepatocyte uptake of various molecules Magdolna G. Sebestyén, Vladimir G. Budker, Tatiana Budker et al. · The Journal of Gene Medicine 25 May 2006 107
20 The Effect of Cell Division on the Cellular Dynamics of Microinjected DNA and Dextran James J. Ludtke, Magdolna G. Sebestyén, Jon A. Wolff · Molecular Therapy Open access May 2002 104
21 A Broad Spectrum Kunitz Type Serine Protease Inhibitor Secreted by the Hookworm Ancylostoma ceylanicum Aaron Michael Milstone, Lisa Marie Harrison, Richard D. Bungiro et al. · Journal of Biological Chemistry Open access Sep 2000 101
22 Layer-by-layer deposition of oppositely charged polyelectrolytes on the surface of condensed DNA particles V.S. Trubetskoy, Andrew H. Loomis, James E. Hagstrom et al. · Nucleic Acids Research Open access Aug 1999 99
23 Analysis of arterial intimal hyperplasia: review and hypothesis Vladimir M. Subbotin · Theoretical Biology and Medical Modelling Open access 31 Oct 2007 92
24 Roles of Serine Accumulation and Catabolism in the Colonization of the Murine Urinary Tract by Escherichia coli CFT073 Andrew Anfora, Brian J. Haugen, Paula L. Roesch et al. · Infection and Immunity Open access 5 Sep 2007 88
25 Caged DNA Does Not Aggregate in High Ionic Strength Solutions Vladimir S. Trubetskoy, Aaron G. Loomis, Paul M. Slattum et al. · Bioconjugate Chemistry 29 May 1999 85
26 Motor Unit Number Index (MUNIX) detects motor neuron loss in pre-symptomatic muscles in Amyotrophic Lateral Sclerosis Christoph Neuwirth, Paul E. Barkhaus, Christian Burkhardt et al. · Clinical Neurophysiology 18 Dec 2016 84
27 Mechanism of plasmid delivery by hydrodynamic tail vein injection. II. Morphological studies Vladimir G. Budker, Vladimir M. Subbotin, Tatiana Budker et al. · The Journal of Gene Medicine 23 May 2006 84
28 Intraarterial Delivery of Naked Plasmid DNA Expressing Full-Length Mouse Dystrophin in the mdx Mouse Model of Duchenne Muscular Dystrophy Goufeng Zhang, James J. Ludtke, Christine Thioudellet et al. · Human Gene Therapy Aug 2004 83
29 Systemic siRNA delivery via hydrodynamic intravascular injection David Levering Lewis, Jon A. Wolff · Advanced Drug Delivery Reviews Review Mar 2007 81
30 Sustained liver‐specific transgene expression from the albumin promoter in mice following hydrodynamic plasmid DNA delivery Christine I. Wooddell, Thomas Reppen, Jon A. Wolff et al. · The Journal of Gene Medicine 10 Mar 2008 71
31 Self-assembly of DNA-polymer complexes using template polymerization Vladimir S. Trubetskoy · Nucleic Acids Research Open access 15 Sep 1998 62
32 Delivery of siRNA and siRNA Expression Constructs to Adult Mammals by Hydrodynamic Intravascular Injection David Levering Lewis, Jon A. Wolff · Methods in enzymology on CD-ROM/Methods in enzymology Book chapter 2005 59
33 Progress Toward A Nonviral Gene Therapy Protocol for The Treatment of Anemia Magdolna G. Sebestyén, Julia O Hegge, Mark Noble et al. · Human Gene Therapy Open access Mar 2007 56
34 Increased hepatic platelet activating factor (PAF) and PAF receptors in carbon tetrachloride induced liver cirrhosis Yilan Yang, E M Nemoto, S A K Harvey et al. · Gut Open access 11 May 2004 53
35 Small proline-rich proteins 2 are noncoordinately upregulated by IL-6/STAT3 signaling after bile duct ligation Isao Nozaki, John G. Lunz, Susan M. Specht et al. · Laboratory Investigation Open access 22 Nov 2004 50
36 Sex differences in hepatic gene expression in a rat model of ethanol-induced liver injury Stasa D. Tadic, Mary S. Elm, Ha-Sheng Li et al. · Journal of Applied Physiology Sep 2002 48
37 Membrane Activity and Transfection Ability of Amphipathic Polycations as a Function of Alkyl Group Size Darren H. Wakefield, Jason J. Klein, Jon A. Wolff et al. · Bioconjugate Chemistry 31 Aug 2005 48
38 Entrapment and Condensation of DNA in Neutral Reverse Micelles Vladimir G. Budker, Paul M. Slattum, Sean D. Monahan et al. · Biophysical Journal Open access Mar 2002 47
39 Portacaval shunt causes apoptosis and liver atrophy in rats despite increases in endogenous levels of major hepatic growth factors Chandrashekhar R. Gandhi, Noriko Murase, Vladimir M. Subbotin et al. · Journal of Hepatology Open access 26 Aug 2002 43
40 Genetic Immunization for Antibody Generation in Research Animals by Intravenous Delivery of Plasmid DNA Mary Kay Bates, Guofeng Zhang, Magdolna G. Sebestyén et al. · BioTechniques Open access Feb 2006 39
41 Differential internalization of hu14.18-IL2 immunocytokine by NK and tumor cell: impact on conjugation, cytotoxicity, and targeting Ilia N. Buhtoiarov, Zane C. Neal, Jacek Gan et al. · Journal of Leukocyte Biology Open access 19 Jan 2011 38
42 Effects of Side Chain Configuration and Backbone Spacing on the Gene Delivery Properties of Lysine-Derived Cationic Polymers Sarah E. Eldred, Margaret R. Pancost, Karin M. Otte et al. · Bioconjugate Chemistry May 2005 38
43 Efficient in vitro and in vivo expression of covalently modified plasmid DNA Paul M. Slattum, Aaron G. Loomis, Kira J Machnik et al. · Molecular Therapy Open access 21 Jun 2003 36
44 Endothelin receptor antagonist TAK-044 arrests and reverses the development of carbon tetrachloride induced cirrhosis in rats Chinnasamy Thirunavukkarasu, Y Yang, V M Subbotin et al. · Gut Open access 11 Jun 2004 35
45 Regulation of Polyamine Analogue Cytotoxicity by c-Jun in Human MDA-MB-435 Cancer Cells Yi Huang, Judith Clancy Keen, Erin R. Hager et al. · Molecular Cancer Research Feb 2004 34
46 Effect of Tissue-Specific Promoters and microRNA Recognition Elements on Stability of Transgene Expression After Hydrodynamic Naked Plasmid DNA Delivery Lisa J. Wolff, Jon A. Wolff, Magdolna G. Sebestyén · Human Gene Therapy 7 Feb 2009 34
47 Rapid Intravascular Injection into Limb Skeletal Muscle: A Damage Assessment Study Hechmi Toumi, Julia O Hegge, Vladimir M. Subbotin et al. · Molecular Therapy Open access 27 Sep 2005 33
48 Long-term RNA interference from optimized siRNA expression constructs in adult mice Christine I. Wooddell, Cristopher V. Van Hout, Thomas Reppen et al. · Biochemical and Biophysical Research Communications 27 Jun 2005 28
49 siRNA delivery technologies for mammalian systems David B. Rozema, David Levering Lewis · TARGETS Dec 2003 26
50 Delivery of Small Interfering RNA to Mammalian Cells in Culture by Using Cationic Lipid⧸Polymer-Based Transfection Reagents Robert M. Brazas, James E. Hagstrom · Methods in enzymology on CD-ROM/Methods in enzymology Book chapter 2005 26

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.