Institution · Mochida Pharmaceutical (Japan)

Most cited papers from Mochida Pharmaceutical (Japan)

Mochida Pharmaceutical (Japan)

What are the most cited papers from Mochida Pharmaceutical (Japan)?

The most cited paper from Mochida Pharmaceutical (Japan) is "Fas ligand in human serum" (Masato Tanaka, Takashi Suda, Kyosuke Haze et al., 1996), with 683 citations. Next come "In vivo transfection of cis element “decoy” against nuclear factor- κB binding site prevents myocardial infarction" (587) and "Antibody recycling by engineered pH-dependent antigen binding improves the duration of antigen neutralization" (359).

Published TypeFieldAccessCitations

Showing 50 of 60 papers. Every paper with more than 105 citations is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	Fas ligand in human serum Masato Tanaka, Takashi Suda, Kyosuke Haze et al. · Nature Medicine	Mar 1996	683
2	In vivo transfection of cis element “decoy” against nuclear factor- κB binding site prevents myocardial infarction Ryuichi Morishita, Toshiko Sugimoto, Motokuni Aoki et al. · Nature Medicine	Aug 1997	587
3	Antibody recycling by engineered pH-dependent antigen binding improves the duration of antigen neutralization Tomoyuki Igawa et al. · Nature Biotechnology	17 Oct 2010	359
4	Establishment of new preparation method for solid dispersion formulation of tacrolimus Kazunari Yamashita, Toshiomi Nakate, Kazuto Okimoto et al. · International Journal of Pharmaceutics	9 Oct 2003	348
5	Essential roles of the Fas-Fas ligand pathway in the development of pulmonary fibrosis Kazuyoshi Kuwano, Naoki Hagimoto, Masayuki Kawasaki et al. · Journal of Clinical Investigation Open access	Jul 1999	347
6	The Keap1-Nrf2 System Prevents Onset of Diabetes Mellitus Akira Uruno, Yuki Furusawa, Yoko Yagishita et al. · Molecular and Cellular Biology Open access	29 May 2013	333
7	Evaluation of a newly identified soluble CD14 subtype as a marker for sepsis Yasunori Yaegashi, Nobuhiro Sato, Yasushi A Suzuki et al. · Journal of Infection and Chemotherapy	2005	327
8	In Vitro Activities of a New Lipopeptide Antifungal Agent, FK463, against a Variety of Clinically Important Fungi Shuichi Tawara, Fumiaki Ikeda, Katsuyuki Maki et al. · Antimicrobial Agents and Chemotherapy Open access	2000	311
9	Characterizations of Three Major Cysteine Sensors of Keap1 in Stress Response Ryota Saito, Takafumi Suzuki, Keiichiro Hiramoto et al. · Molecular and Cellular Biology Open access	2 Nov 2015	296
10	Increased Adiponectin Secretion by Highly Purified Eicosapentaenoic Acid in Rodent Models of Obesity and Human Obese Subjects Michiko Itoh, Takayoshi Suganami, Noriko Satoh et al. · Arteriosclerosis Thrombosis and Vascular Biology Open access	15 Jun 2007	295
11	Reshaping a human antibody to inhibit the interleukin 6-dependent tumor cell growth. Koh Sato, Masayuki Tsuchiya, José W. Saldanha et al. · PubMed	15 Feb 1993	278
12	Identification of novel adrenomedullin in mammals: a potent cardiovascular and renal regulator Yoshio Takei, Koji Inoue, Maho Ogoshi et al. · FEBS Letters Open access	4 Dec 2003	270
13	Reduced elimination of IgG antibodies by engineering the variable region Tomoyuki Igawa, Hiroyuki Tsunoda, Tatsuhiko Tachibana et al. · Protein Engineering Design and Selection	15 Feb 2010	266
14	Type II collagen-induced murine arthritis. I. Induction and perpetuation of arthritis require synergy between humoral and cell-mediated immunity. Nobuo Seki, Yuji Sudo, Tatsunobu Yoshioka et al. · The Journal of Immunology	Mar 1988	261
15	FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum No. 968. III. Antitumor activities on experimental tumors in mice. Hirotsugu Ueda, Toshitaka Manda, Sanae Matsumoto et al. · The Journal of Antibiotics Open access	1994	260
16	Inhibition of IgE‐dependent histamine release from human dispersed lung mast cells by anti‐allergic drugs and salbutamol Martin K. Church, Jun Hiroi · British Journal of Pharmacology Open access	Feb 1987	250
17	Taxonomy, Fermentation, Isolation and Biological Activities. Hiroaki Mori, Yasuharu Urano, Fumie Abe et al. · The Journal of Antibiotics Open access	2003	236
18	New Antitumor Substances, FR901463, FR901464 and FR901465. II. Activities against Experimental Tumors in Mice and Mechanism of Action. Hidenori Nakajima, Yasuhiro Hori, Hiroshi Terano et al. · The Journal of Antibiotics Open access	1996	218
19	Molecular Cloning and Characterization of a Surface Antigen Preferentially Overexpressed on Multiple Myeloma Cells Toshihiko Ohtomo, Yasuhiro Sugamata, Yasuko Ozaki et al. · Biochemical and Biophysical Research Communications	May 1999	203
20	TGF-β1 as an Enhancer of Fas-Mediated Apoptosis of Lung Epithelial Cells Naoki Hagimoto, Kazuyoshi Kuwano, Ichiro Inoshima et al. · The Journal of Immunology	Jun 2002	202
21	INTERLEUKIN-6 (IL-6) INDUCES THE PROLIFERATION OF SYNOVIAL FIBROBLASTIC CELLS IN THE PRESENCE OF SOLUBLE IL-6 RECEPTOR Masahiko Mihara, Yoichiro Moriya, Tadamitsu Kishimoto et al. · Lara D. Veeken	1995	201
22	Dienogest is a selective progesterone receptor agonist in transactivation analysis with potent oral endometrial activity due to its efficient pharmacokinetic profile Shinichi Sasagawa, Yutaka Shimizu, Hideaki Kami et al. · Steroids	9 Nov 2007	188
23	A New Spontaneously Diabetic Non‐obese Torii Rat Strain With Severe Ocular Complications Masami Shinohara, Taku Masuyama, Toshiyuki Shoda et al. · Journal of Diabetes Research Open access	30 Dec 1999	178
24	Gasdermin D–mediated release of IL-33 from senescent hepatic stellate cells promotes obesity-associated hepatocellular carcinoma Ryota Yamagishi et al. · Science Immunology Open access	24 Jun 2022	175
25	ADP ribosyl cyclase activity of a novel bone marrow stromal cell surface molecule, BST‐1 Yuichi Hirata, Naoki Kimura, Koh Sato et al. · FEBS Letters Open access	19 Dec 1994	171
26	Constitutive Expression of Aryl Hydrocarbon Receptor in Keratinocytes Causes Inflammatory Skin Lesions Masafumi Tauchi, Azumi Hida, Takaaki Negishi et al. · Molecular and Cellular Biology Open access	14 Oct 2005	168
27	Sonophoresis. II. Examination of the Mechanism(s) of Ultrasound-Enhanced Transdermal Drug Delivery D. Bommi Bommannan, Gopinathan K. Menon, Hirohisa Okuyama et al. · Pharmaceutical Research	Aug 1992	166
28	Antiobesity Effect of Eicosapentaenoic Acid in High-Fat/High-Sucrose Diet–Induced Obesity Ayumi Sato, Hiroyuki Kawano, Tatsuto Notsu et al. · Diabetes Open access	3 Aug 2010	161
29	Lethal effect of recombinant human Fas ligand in mice pretreated with Propionibacterium acnes Masato Tanaka, Takashi Suda, T Yatomi et al. · The Journal of Immunology	Mar 1997	161
30	Purification and Characterization of Soluble Human IL-6 Receptor Expressed in CHO Cells Kiyoshi Yasukawa, Takashi Saito, Takeshi Fukunaga et al. · The Journal of Biochemistry	Oct 1990	151
31	A highly sensitive method to assay FK-506 levels in plasma. Kyoichi Tamura, Minoru Kobayashi, Kazuhiko Hashimoto et al. · PubMed	Oct 1987	148
32	IgE Hyperproduction Through Enhanced Tyrosine Phosphorylation of Janus Kinase 3 in NC/Nga Mice, a Model for Human Atopic Dermatitis Masahiro Matsumoto, Chisei Ra, Keiko Kawamoto et al. · The Journal of Immunology Open access	1999	146
33	Increased Very Low Density Lipoprotein Secretion and Gonadal Fat Mass in Mice Overexpressing Liver DGAT1 Tomomi Yamazaki, Eriko Sasaki, Chihaya Kakinuma et al. · Journal of Biological Chemistry Open access	30 Mar 2005	145
34	Eicosapentaenoic Acid Enhances Nitric Oxide Production by Cultured Human Endothelial Cells Yukichi Okuda, Kazuko Kawashima, Toshie Sawada et al. · Biochemical and Biophysical Research Communications	Mar 1997	142
35	Sphingosylphosphorylcholine Is a Novel Messenger for Rho-Kinase–Mediated Ca 2+ Sensitization in the Bovine Cerebral Artery Satoshi Shirao, Shiro Kashiwagi, Masafumi Sato et al. · Circulation Research	26 Jul 2002	141
36	Pharmacological profile of a high affinity dipeptide NK1 receptor antagonist, FK888 Takashi Fujii, Masako Murai, Hiroshi Morimoto et al. · British Journal of Pharmacology Open access	Nov 1992	141
37	Engineering the variable region of therapeutic IgG antibodies Tomoyuki Igawa, Hiroyuki Tsunoda, Taichi Kuramochi et al. · mAbs Open access	May 2011	139
38	Repeated administration of low-dose lipopolysaccharide induces preterm delivery in mice: A model for human preterm parturition and for assessment of the therapeutic ability of drugs against preterm delivery Nobuhiko Kaga, Yukio Katsuki, Masaomi Obata et al. · American Journal of Obstetrics and Gynecology	Feb 1996	139
39	FR901483, a Novel Immunosuppressant Isolated from Cladobotryum sp. No. 11231. Taxonomy of the Producing Organism, Fermentation, Isolation,Physico-chemical Properties and Biological Activities. Kazutoshi Sakamoto, Eisaku Tsujii, Fumie Abe et al. · The Journal of Antibiotics Open access	1996	138
40	Rapid induction of more malignant tumors by various genotoxic carcinogens in transgenic mice harboring a human prototype c-Ha-ras gene than in control non-transgenic mice Satoshi Yamamoto, Kunitoshi Mitsumori, Yukio Kodama et al. · Carcinogenesis Open access	1996	134
41	Effects of Aryl Hydrocarbon Receptor Signaling on the Modulation of Th1/Th2 Balance Takaaki Negishi, Yutaka Kato, Osamu Ooneda et al. · The Journal of Immunology Open access	Dec 2005	133
42	Metabolism of FK506, a potent immunosuppressive agent, by cytochrome P450 3A enzymes in rat, dog and human liver microsomes Toshipumi Shiraga, Hiroji Matsuda, Kazuko Nagase et al. · Biochemical Pharmacology	Feb 1994	131
43	Tacrolimus suppressed the production of cytokines involved in atopic dermatitis by direct stimulation of human PBMC system. (Comparison with steroids) Shozo Sakuma, Yasuyuki Higashi, Natuki Sato et al. · International Immunopharmacology	Jun 2001	127
44	Evaluation of the efficacy and safety of dienogest in the treatment of painful symptoms in patients with adenomyosis: a randomized, double-blind, multicenter, placebo-controlled study Yutaka Osuga, Haruka Fujimoto-Okabe, Atsushi Hagino · Fertility and Sterility Open access	11 Sep 2017	122
45	Structural Characterization of Natural and Recombinant Human Granulocyte Colony-Stimulating Factors1 Naoki Kubota, Tetsuro Orita, Kunihiro Hattori et al. · The Journal of Biochemistry	Mar 1990	120
46	The pharmacology of the integrins Dermot M Cox, Toshiaki Aoki, Jiro Seki et al. · Medicinal Research Reviews	Mar 1994	118
47	Distribution and Protein Binding of FK506, a Potent Immunosuppressive Macrolide Lactone, in Human Blood and Its Uptake by Erythrocytes Kazuko Nagase, Kazuhide Iwasaki, Katsuko Nozaki et al. · Journal of Pharmacy and Pharmacology	Feb 1994	117
48	Molecular cloning and nucleotide sequence of the HU-1 gene of Escherichia coli Yasunobu Kano, Setsuo Yoshino, Morimasa Wada et al. · Molecular and General Genetics MGG	Nov 1985	114
49	Spontaneous nitric oxide release accounts for the potent pharmacological actions of FK409 Yasuhiro Kita, Yoshimi Hirasawa, Kazuhiro Maeda et al. · European Journal of Pharmacology	May 1994	112
50	A long-acting anti–IL-8 antibody improves inflammation and fibrosis in endometriosis Ayako Nishimoto, Izumi Sato, Kiyotaka Nakano et al. · Science Translational Medicine	22 Feb 2023	111

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.