Most cited papers from Myriad Genetics

Myriad Genetics

What are the most cited papers from Myriad Genetics?

The most cited paper from Myriad Genetics is "A Strong Candidate for the Breast and Ovarian Cancer Susceptibility Gene BRCA1" (Yoshio Miki et al., 1994), with 6,134 citations. Next come "A Draft Sequence of the Rice Genome ( Oryza sativa L. ssp. japonica )" (2,915) and "A Cell Cycle Regulator Potentially Involved in Genesis of Many Tumor Types" (2,798).

Published TypeFieldAccessCitations

Showing 50 of 60 papers. Every paper with more than 298 citations is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	A Strong Candidate for the Breast and Ovarian Cancer Susceptibility Gene BRCA1 Yoshio Miki et al. · Science	7 Oct 1994	6,134
2	A Draft Sequence of the Rice Genome ( Oryza sativa L. ssp. japonica ) Stephen A. Goff et al. · Science	5 Apr 2002	2,915
3	A Cell Cycle Regulator Potentially Involved in Genesis of Many Tumor Types Alexander Kamb, Nelleke A. Gruis, Jane Weaver-Feldhaus et al. · Science	15 Apr 1994	2,798
4	Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers Peter A. Steck, Mark A. Pershouse, Samar A. Jasser et al. · Nature Genetics	Apr 1997	2,772
5	The genome of the domesticated apple (Malus × domestica Borkh.) Riccardo Velasco et al. · Nature Genetics	27 Aug 2010	2,158
6	Lynch Syndrome Patients with Limited Family History Identified in a Laboratory Setting: A Descriptive Study Michelle Landon, Jennifer R. Saam, Krystal L. Brown et al. · Oncology Open access	2015	1,942
7	Whole-Genome Shotgun Assembly and Analysis of the Genome of Fugu rubripes Samuel A. J. R. Aparicio et al. · Science	23 Aug 2002	1,634
8	Patients Tested at a Laboratory for Hereditary Cancer Syndromes Show an Overlap for Multiple Syndromes in Their Personal and Familial Cancer Histories Jennifer R. Saam, Christopher Arnell, Aaron P. Theisen et al. · Oncology Open access	2015	1,528
9	Tsg101 and the Vacuolar Protein Sorting Pathway Are Essential for HIV-1 Budding Jennifer E. Garrus, Uta K. von Schwedler, Owen Pornillos et al. · Cell Open access	Oct 2001	1,387
10	BRCA1 Mutations in Primary Breast and Ovarian Carcinomas P. Andrew Futreal et al. · Science	7 Oct 1994	1,212
11	Kcnq1ot1 Antisense Noncoding RNA Mediates Lineage-Specific Transcriptional Silencing through Chromatin-Level Regulation Radha Raman Pandey, Tanmoy Mondal, Faizaan Mohammad et al. · Molecular Cell Open access	Oct 2008	1,200
12	Homologous Recombination Deficiency (HRD) Score Predicts Response to Platinum-Containing Neoadjuvant Chemotherapy in Patients with Triple-Negative Breast Cancer Melinda L. Telli et al. · Clinical Cancer Research Open access	8 Mar 2016	1,198
13	A High Quality Draft Consensus Sequence of the Genome of a Heterozygous Grapevine Variety Riccardo Velasco et al. · PLoS ONE Open access	18 Dec 2007	1,106
14	Carboplatin in BRCA1/2-mutated and triple-negative breast cancer BRCAness subgroups: the TNT Trial Andrew N.J. Tutt et al. · Nature Medicine Open access	27 Apr 2018	920
15	A New Definition of Genetic Counseling: National Society of Genetic Counselors’ Task Force Report Robert G. Resta, Barbara Bowles Biesecker, Robin L. Bennett et al. · Journal of Genetic Counseling Open access	Apr 2006	903
16	Patterns of genomic loss of heterozygosity predict homologous recombination repair defects in epithelial ovarian cancer Victor Abkevich, Kirsten M. Timms, Bryan T. Hennessy et al. · British Journal of Cancer Open access	9 Oct 2012	870
17	Analysis of the p16 gene (CDKN2) as a candidate for the chromosome 9p melanoma susceptibility locus Alexander Kamb et al. · Nature Genetics	Sep 1994	856
18	The complete BRCA2 gene and mutations in chromosome 13q-linked kindreds Sean V. Tavtigian et al. · Nature Genetics	Mar 1996	845
19	Clinical Characteristics of Individuals With Germline Mutations in BRCA1 and BRCA2: Analysis of 10,000 Individuals Thomas Frank · Journal of Clinical Oncology	15 Mar 2002	827
20	The Protein Network of HIV Budding Uta K. von Schwedler, Melissa D. Stuchell, Barbara Theresia Müller et al. · Cell Open access	Sep 2003	825
21	Prognostic value of an RNA expression signature derived from cell cycle proliferation genes in patients with prostate cancer: a retrospective study Jack M. Cuzick, Gregory P. Swanson, Gabrielle Fisher et al. · The Lancet Oncology Open access	9 Feb 2011	821
22	Efficacy of Bilateral Prophylactic Mastectomy in BRCA1 and BRCA2 Gene Mutation Carriers Lynn C. Hartmann, Thomas A. Sellers, Daniel J. Schaid et al. · JNCI Journal of the National Cancer Institute	7 Nov 2001	749
23	Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis Eiji Morita, Virginie Sandrin, Hyo-Young Chung et al. · The EMBO Journal Open access	13 Sep 2007	741
24	Prevalence and Spectrum of Germline Cancer Susceptibility Gene Mutations Among Patients With Early-Onset Colorectal Cancer Rachel Pearlman et al. · JAMA Oncology Open access	19 Dec 2016	739
25	Regulation of p16 CDKN2 Expression and Its Implications for Cell Immortalization and Senescence Eiji Hara, Rosalind Smith, David A.D. Parry et al. · Molecular and Cellular Biology Open access	Mar 1996	732
26	Comprehensive statistical study of 452 BRCA1 missense substitutions with classification of eight recurrent substitutions as neutral Sean V. Tavtigian, A M Deffenbaugh, L Yin et al. · Journal of Medical Genetics Open access	13 Jul 2005	677
27	NCCN Guidelines Insights: Genetic/Familial High-Risk Assessment: Breast and Ovarian, Version 2.2017 Mary B. Daly et al. · Journal of the National Comprehensive Cancer Network Open access	31 Dec 2016	664
28	Follow-up of Prostatectomy versus Observation for Early Prostate Cancer Timothy J Wilt, Karen M. Jones, Michael J. Barry et al. · New England Journal of Medicine Open access	12 Jul 2017	624
29	NSAIDs and enantiomers of flurbiprofen target γ-secretase and lower Aβ42 in vivo Jason L. Eriksen, Sarah A. Sagi, Tawnya E. Smith et al. · Journal of Clinical Investigation Open access	Aug 2003	623
30	Incidence and Outcome of BRCA Mutations in Unselected Patients with Triple Receptor-Negative Breast Cancer Ana Maria Gonzalez-Angulo, Kirsten M. Timms, Shuying Liu et al. · Clinical Cancer Research Open access	14 Jan 2011	606
31	Clinical Characteristics of Individuals With Germline Mutations in BRCA1 and BRCA2 : Analysis of 10,000 Individuals Thomas S. Frank, Amie M. Deffenbaugh, Julia Reid et al. · Journal of Clinical Oncology	15 Mar 2002	562
32	A candidate prostate cancer susceptibility gene at chromosome 17p Sean V. Tavtigian et al. · Nature Genetics	Feb 2001	556
33	RAD51 Interacts with the Evolutionarily Conserved BRC Motifs in the Human Breast Cancer Susceptibility Gene brca2 Alexander K.C. Wong, Ralph S. Pero, Patricia A. Ormonde et al. · Journal of Biological Chemistry Open access	Dec 1997	545
34	A single BRCA2 mutation in male and female breast cancer families from Iceland with varied cancer phenotypes Steinunn Thorlacius, Guðríður H. Ólafsdóttir, Laufey Tryggvadóttír et al. · Nature Genetics	May 1996	531
35	MMAC1/PTEN mutations in primary tumor specimens and tumor cell lines. Dahong Teng et al. · PubMed	Dec 1997	470
36	Sequence analysis of BRCA1 and BRCA2: correlation of mutations with family history and ovarian cancer risk. Thomas S. Frank et al. · Journal of Clinical Oncology	Jul 1998	461
37	A Systematic Genetic Assessment of 1,433 Sequence Variants of Unknown Clinical Significance in the BRCA1 and BRCA2 Breast Cancer–Predisposition Genes Douglas F. Easton, Amie M. Deffenbaugh, Dmitry Pruss et al. · The American Journal of Human Genetics Open access	19 Oct 2007	459
38	TBCRC009: A Multicenter Phase II Clinical Trial of Platinum Monotherapy With Biomarker Assessment in Metastatic Triple-Negative Breast Cancer Steven Jay Isakoff, Erica L. Mayer, Lei He et al. · Journal of Clinical Oncology Open access	7 Apr 2015	439
39	Frequency of mutations in individuals with breast cancer referred for BRCA 1 and BRCA 2 testing using next‐generation sequencing with a 25‐gene panel Nadine Tung, Chiara Battelli, Brian A Allen et al. · Cancer Open access	3 Sep 2014	439
40	Association of BRCA1/2defects with genomic scores predictive of DNA damage repair deficiency among breast cancer subtypes Kirsten M. Timms, Victor Abkevich, Elisha Hughes et al. · Breast Cancer Research Open access	4 Dec 2014	431
41	Reduced susceptibility to ischemic brain injury and N -methyl- d -aspartate-mediated neurotoxicity in cyclooxygenase-2-deficient mice Costantino Iadecola, Kiyoshi Niwa, Shigeru Nogawa et al. · Proceedings of the National Academy of Sciences Open access	30 Jan 2001	416
42	Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis Francesca Capon, Paola Di Meglio, Joanna Szaub et al. · Human Genetics	21 Jun 2007	416
43	A study of over 35,000 women with breast cancer tested with a 25‐gene panel of hereditary cancer genes Saundra S. Buys, John F. Sandbach, Amanda Gammon et al. · Cancer Open access	13 Jan 2017	414
44	Complex structure and regulation of the P16 (MTS1) locus. Steven Stone, Ping Jiang, Priya Dayananth et al. · PubMed	15 Jul 1995	396
45	Integrated Evaluation of DNA Sequence Variants of Unknown Clinical Significance: Application to BRCA1 and BRCA2 David E. Goldgar, Douglas F. Easton, Amie M. Deffenbaugh et al. · The American Journal of Human Genetics Open access	12 Sep 2004	392
46	BRCA1 and BRCA2 mutations in women of different ethnicities undergoing testing for hereditary breast‐ovarian cancer Michael J. Hall, Julia Reid, Lynn Anne Burbidge et al. · Cancer Open access	24 Feb 2009	377
47	Somatic Mutations in BRCA1 and BRCA2 Could Expand the Number of Patients That Benefit From Poly (ADP Ribose) Polymerase Inhibitors in Ovarian Cancer Bryan T. Hennessy, Kirsten M. Timms, Mark Stafford Carey et al. · Journal of Clinical Oncology Open access	7 Jul 2010	374
48	Prognostic value of a cell cycle progression signature for prostate cancer death in a conservatively managed needle biopsy cohort on behalf of the Transatlantic Prostate Group, Jack M. Cuzick, Daniel Maurice Berney et al. · British Journal of Cancer Open access	23 Feb 2012	369
49	BRG1, a component of the SWI-SNF complex, is mutated in multiple human tumor cell lines. Andrew Kai Cheung Wong, Fergus Shanahan, Joseph C. Y. Chen et al. · PubMed	Nov 2000	366
50	BRCA2 germline mutations in male breast cancer cases and breast cancer families Fergus J. Couch, Linda M. Farid, Michelle L. DeShano et al. · Nature Genetics	May 1996	365

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.