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Most cited papers from Nanotherapeutics (United States)

What are the most cited papers from Nanotherapeutics (United States)?

The most cited paper from Nanotherapeutics (United States) is "Guidelines for the Early Management of Adults With Ischemic Stroke" (Harold P. Adams, Gregory del Zoppo, Mark J. Alberts et al., 2007), with 2,479 citations. Next come "Guidelines for Prevention of Stroke in Patients With Ischemic Stroke or Transient Ischemic Attack" (1,883) and "Definition and Evaluation of Transient Ischemic Attack" (1,854).

Showing 50 of 60 papers. Every paper with more than 138 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Guidelines for the Early Management of Adults With Ischemic Stroke Harold P. Adams, Gregory del Zoppo, Mark J. Alberts et al. · Stroke 12 Apr 2007 2,479
2 Guidelines for Prevention of Stroke in Patients With Ischemic Stroke or Transient Ischemic Attack Ralph L. Sacco, Robert J. Adams, Gregory W. Albers et al. · Stroke 23 Jan 2006 1,883
3 Definition and Evaluation of Transient Ischemic Attack J. Donald Easton, Jeffrey L. Saver, Gregory W. Albers et al. · Stroke 7 May 2009 1,854
4 Primary Prevention of Ischemic Stroke Larry B. Goldstein, Robert J. Adams, Mark J. Alberts et al. · Stroke Open access 4 May 2006 1,371
5 Regulation of antibacterial defense in the small intestine by the nuclear bile acid receptor Takeshi Inagaki, Antonio Moschetta, Youn-Kyoung Lee et al. · Proceedings of the National Academy of Sciences 10 Feb 2006 1,174
6 Time to Treatment With Intravenous Tissue Plasminogen Activator and Outcome From Acute Ischemic Stroke Jeffrey L. Saver, Gregg C. Fonarow, Eric Edward Smith et al. · JAMA 18 Jun 2013 887
7 Sulfonyl fluorides as privileged warheads in chemical biology Arjun Narayanan, Lyn H. Jones · Chemical Science Open access 2015 555
8 Polypharmacy as commonly defined is an indicator of limited value in the assessment of drug‐related problems Kirsten Kilvik Viktil, Hege Salvesen Blix, Tron Anders Moger et al. · British Journal of Clinical Pharmacology Open access 30 Aug 2006 543
9 Type II monocytes modulate T cell–mediated central nervous system autoimmune disease Martin S. Weber, Thomas Prod’homme, Sawsan Youssef et al. · Nature Medicine Aug 2007 449
10 The Classification of Microglial Activation Phenotypes on Neurodegeneration and Regeneration in Alzheimer’s Disease Brain Megan M. Varnum, Tsuneya Ikezu · Archivum Immunologiae et Therapiae Experimentalis Open access 18 Jun 2012 407
11 The primary periodic paralyses: diagnosis, pathogenesis and treatment Shannon L. Venance, Stephen C. Cannon, Doreen Fialho et al. · Brain 29 Sep 2005 371
12 Acute Disseminated Encephalomyelitis Til Menge, Bernhard Hemmer, Stefan Nessler et al. · Archives of Neurology Nov 2005 369
13 Restricted Expression of G86R Cu/Zn Superoxide Dismutase in Astrocytes Results in Astrocytosis But Does Not Cause Motoneuron Degeneration Yun H. Gong, Alexander Sh. Parsadanian, Albina Andreeva et al. · Journal of Neuroscience Open access 15 Jan 2000 365
14 Cholesterol 24-Hydroxylase: An Enzyme of Cholesterol Turnover in the Brain David W. Russell, Rebekkah W. Halford, Denise M. O. Ramirez et al. · Annual Review of Biochemistry ReviewOpen access 9 Jan 2009 337
15 Protective effect of encapsulated cells producing neurotrophic factor CNTF in a monkey model of Huntington's disease Dwaine F. Emerich, Shelley R. Winn, Philippe Hantraye et al. · Nature Mar 1997 325
16 Leukocyte Common Antigen-Related Phosphatase Is a Functional Receptor for Chondroitin Sulfate Proteoglycan Axon Growth Inhibitors Daniel W. Fisher, Bin Xing, John C. Dill et al. · Journal of Neuroscience Open access 5 Oct 2011 316
17 Implications of receptor-mediated endocytosis and intracellular trafficking dynamics in the development of antibody drug conjugates Michael F. Ritchie, Lioudmila Tchistiakova, Nathan Scott · mAbs Open access 2013 313
18 Loss of Predominant Shank3 Isoforms Results in Hippocampus-Dependent Impairments in Behavior and Synaptic Transmission Mehreen Kouser, Haley E. Speed, Colleen M. Dewey et al. · Journal of Neuroscience Open access 20 Nov 2013 304
19 Gene expression during sex determination reveals a robust female genetic program at the onset of ovarian development Serge Nef, Olivier Schaad, Nancy R. Stallings et al. · Developmental Biology Open access Nov 2005 290
20 Andrographolide and its analogues: versatile bioactive molecules for combating inflammation and cancer Jonathan Chee Woei Lim, Tze Khee Chan, David S.W. Ng et al. · Clinical and Experimental Pharmacology and Physiology 21 Oct 2011 268
21 Brain cholesterol turnover required for geranylgeraniol production and learning in mice Tiina J. Kotti, Denise M. O. Ramirez, Brad E. Pfeiffer et al. · Proceedings of the National Academy of Sciences 27 Feb 2006 261
22 Multifocal acquired demyelinating sensory and motor neuropathy: The Lewis-Sumner syndrome David Saperstein, Anthony A. Amato, Gil I. Wolfe et al. · Muscle & Nerve May 1999 259
23 Magnetic nanoscale metal organic frameworks for potential targeted anticancer drug delivery, imaging and as an MRI contrast agent Angshuman Ray Chowdhuri, Dipsikha Bhattacharya, Sumanta Kumar Sahu · Dalton Transactions 23 Dec 2015 251
24 Myelinogenesis and Axonal Recognition by Oligodendrocytes in Brain Are Uncoupled inOlig1-Null Mice Mei Xin, Tao Yue, Zhenyi Ma et al. · Journal of Neuroscience Open access 9 Feb 2005 251
25 Detouring of cisplatin to access mitochondrial genome for overcoming resistance Sean Marrache, Rakesh Pathak, Shanta Dhar · Proceedings of the National Academy of Sciences Open access 7 Jul 2014 246
26 A Randomized, Double-blind, Placebo-Controlled Trial of Subcutaneously Injected Apomorphine for Parkinsonian Off-State Events Richard B. Dewey, J. Thomas Hutton, Peter A. LeWitt et al. · Archives of Neurology Sep 2001 246
27 Plasma and Fecal Metabolite Profiles in Autism Spectrum Disorder Brittany D. Needham, Mark D. Adame, Gloria Serena et al. · Biological Psychiatry Open access 10 Oct 2020 244
28 Relationships Between Retinal Axonal and Neuronal Measures and Global Central Nervous System Pathology in Multiple Sclerosis Shiv Saidha, Elias S. Sotirchos, Jiwon Oh et al. · JAMA Neurology Open access 2013 232
29 Implants of Encapsulated Human CNTF-Producing Fibroblasts Prevent Behavioral Deficits and Striatal Degeneration in a Rodent Model of Huntington’s Disease Dwaine F. Emerich, Mark D. Lindner, Shelley R. Winn et al. · Journal of Neuroscience Open access 15 Aug 1996 209
30 Macular Volume Determined by Optical Coherence Tomography as a Measure of Neuronal Loss in Multiple Sclerosis Bryn M. Burkholder, Benjamin Osborne, Michael J. Loguidice et al. · Archives of Neurology Open access Nov 2009 200
31 Implants of polymer‐encapsulated human NGF‐secreting cells in the nonhuman primate: Rescue and sprouting of degenerating cholinergic basal forebrain neurons Dwaine F. Emerich, Shelley R. Winn, James S. Harper et al. · The Journal of Comparative Neurology Nov 1994 199
32 In vivo chemical exchange saturation transfer imaging allows early detection of a therapeutic response in glioblastoma Koji Sagiyama, Tomoyuki Mashimo, Osamu Togao et al. · Proceedings of the National Academy of Sciences Open access 10 Mar 2014 197
33 Zika Virus: Medical Countermeasure Development Challenges Robert W. Malone, E. Jane Homan, Michael V. Callahan et al. · PLoS neglected tropical diseases Open access 2 Mar 2016 192
34 ZMYND8 acetylation mediates HIF-dependent breast cancer progression and metastasis Yan Chen, Bo Zhang, Lei Bao et al. · Journal of Clinical Investigation Open access 8 Apr 2018 187
35 Increased Risk of Late Posttraumatic Seizures Associated With Inheritance of APOE ϵ4 Allele Ramon R. Diaz-Arrastia, Yunhua Gong, Suzette Fair et al. · Archives of Neurology Jun 2003 187
36 On the theory of membrane fusion. The stalk mechanism. Markin Vs, Kozlov Mm, Borovjagin Vl · PubMed Oct 1984 186
37 Approaches to discover non-ATP site kinase inhibitors Lori Krim Gavrin, Eddine Saiah · MedChemComm 29 Aug 2012 186
38 Middle interhemispheric variant of holoprosencephaly Alan J. Lewis, Erin M. Simon, Anthony James Barkovich et al. · Neurology 24 Dec 2002 186
39 Protection of Encapsulated Human Islets Implanted Without Immunosuppression in Patients With Type I or Type II Diabetes and in Nondiabetic Control Subjects David W. Scharp, C Swanson, Barbara J. Olack et al. · Diabetes Sep 1994 184
40 Large intestine–targeted, nanoparticle-releasing oral vaccine to control genitorectal viral infection Qing Zhu, James Talton, Guofeng Zhang et al. · Nature Medicine Open access 15 Jul 2012 182
41 Porcine Endogenous Retrovirus Transmission Characteristics of an Inbred Herd of Miniature Swine Beth A. Oldmixon, James C. S. Wood, Thomas A. Ericsson et al. · Journal of Virology Open access 15 Mar 2002 180
42 Cytokine upregulation in a murine model of familial amyotrophic lateral sclerosis Jeffrey L. Elliott · Molecular Brain Research Nov 2001 180
43 Neuroprotective Gene Therapy for Huntington’s Disease Using a Polymer Encapsulated BHK Cell Line Engineered to Secrete Human CNTF Anne‐Catherine Bachoud‐Lévi, Nicole Déglon, Jean‐Paul Nguyen et al. · Human Gene Therapy Open access 10 Aug 2000 172
44 Polymer Encapsulated Cell Lines Genetically Engineered to Release Ciliary Neurotrophic Factor Can Slow Down Progressive Motor Neuronopathy in the Mouse Yves Sagot, Sanda Tan, E. Edward Baetge et al. · European Journal of Neuroscience Jun 1995 169
45 Gating-Spring Models of Mechanoelectrical Transduction by Hair Cells of the Internal Ear Vladislav S. Markin, Albert James Hudspeth · Annual Review of Biophysics and Biomolecular Structure Jun 1995 161
46 Targeted nanoparticles in mitochondrial medicine Rakesh Pathak, Nagesh Kolishetti, Shanta Dhar · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology Open access 27 Oct 2014 161
47 Overexpression of CCS in G93A-SOD1 mice leads to accelerated neurological deficits with severe mitochondrial pathology Marjatta Son, Krishna Puttaparthi, Hibiki Kawamata et al. · Proceedings of the National Academy of Sciences Open access 27 Mar 2007 160
48 Fusion-dependent formation of lipid nanoparticles containing macromolecular payloads Jayesh A. Kulkarni, Dominik Witzigmann, Jerry Leung et al. · Nanoscale Open access 2019 158
49 The Impact of Efflux Transporters in the Brain on the Development of Drugs for CNS Disorders Eve M. Taylor · Clinical Pharmacokinetics 2002 153
50 Autism-Associated Insertion Mutation (InsG) of Shank3 Exon 21 Causes Impaired Synaptic Transmission and Behavioral Deficits Haley E. Speed, Mehreen Kouser, Zhong Xuan et al. · Journal of Neuroscience Open access Jul 2015 152

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.