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4 Mar 2021 |
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Pyroptosis: mechanisms and diseases
Pian Yu, Xu Zhang, Nian Liu et al. · Signal Transduction and Targeted Therapy
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28 Mar 2021 |
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Ferroptosis, a new form of cell death: opportunities and challenges in cancer
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29 Mar 2019 |
2,025 |
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Osimertinib in Resected EGFR -Mutated Non–Small-Cell Lung Cancer
Yi-Long Lung Cancer Wu et al. · New England Journal of Medicine
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19 Sep 2020 |
1,809 |
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Comparison of the efficacy and safety of rosuvastatin versus atorvastatin, simvastatin, and pravastatin across doses (STELLAR**STELLAR = Statin Therapies for Elevated Lipid Levels compared Across doses to Rosuvastatin. Trial)
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Perioperative Pembrolizumab for Early-Stage Non–Small-Cell Lung Cancer
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3 Jun 2023 |
1,142 |
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Endoplasmic reticulum stress: molecular mechanism and therapeutic targets
Xingyi Chen, Chaoran Shi, Meihui He et al. · Signal Transduction and Targeted Therapy
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14 Sep 2023 |
1,010 |
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Clinical Features of 85 Fatal Cases of COVID-19 from Wuhan. A Retrospective Observational Study
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3 Apr 2020 |
999 |
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National Lipid Association Recommendations for Patient-Centered Management of Dyslipidemia: Part 1—Full Report
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792 |
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National Lipid Association Recommendations for Patient-Centered Management of Dyslipidemia: Part 2
Terry A. Jacobson et al. · Journal of clinical lipidology
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18 Sep 2015 |
792 |
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Perioperative Durvalumab for Resectable Non–Small-Cell Lung Cancer
John Victor Heymach et al. · New England Journal of Medicine
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23 Oct 2023 |
780 |
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Regulatory mechanisms of PD-1/PD-L1 in cancers
Xin Lin, Kuan Kang, Pan Chen et al. · Molecular Cancer
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18 May 2024 |
772 |
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Glioma targeted therapy: insight into future of molecular approaches
Keyang Yang, Zhijing Wu, Hao Zhang et al. · Molecular Cancer
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8 Feb 2022 |
738 |
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Daratumumab-Based Treatment for Immunoglobulin Light-Chain Amyloidosis
Efstathios Kastritis et al. · New England Journal of Medicine
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30 Jun 2021 |
703 |
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Cardiac Myosin Activation with Omecamtiv Mecarbil in Systolic Heart Failure
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13 Nov 2020 |
662 |
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Renin-angiotensin system inhibitors improve the clinical outcomes of COVID-19 patients with hypertension
Juan Meng, Guohui Xiao, Juanjuan Zhang et al. · Emerging Microbes & Infections
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650 |
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Roxadustat Treatment for Anemia in Patients Undergoing Long-Term Dialysis
Nan Chen et al. · New England Journal of Medicine
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24 Jul 2019 |
631 |
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Kinetics of viral load and antibody response in relation to COVID-19 severity
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7 Jul 2020 |
602 |
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Roxadustat for Anemia in Patients with Kidney Disease Not Receiving Dialysis
Nan Chen et al. · New England Journal of Medicine
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24 Jul 2019 |
587 |
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Aberrant gut microbiota alters host metabolome and impacts renal failure in humans and rodents
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2 Apr 2020 |
583 |
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The impact of the gut microbiota on the reproductive and metabolic endocrine system
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2021 |
565 |
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Regulatory mechanisms of immune checkpoints PD-L1 and CTLA-4 in cancer
Hao Zhang, Ziyu Dai, Wantao Wu et al. · Journal of Experimental & Clinical Cancer Research
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4 Jun 2021 |
547 |
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Towards an improved investment approach for an effective response to HIV/AIDS
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Altered metabolism in cancer: insights into energy pathways and therapeutic targets
Muhammad Tufail, Canhua Jiang, Ning Li · Molecular Cancer
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18 Sep 2024 |
514 |
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Safety and Efficacy of a Monoclonal Antibody to Proprotein Convertase Subtilisin/Kexin Type 9 Serine Protease, SAR236553/REGN727, in Patients With Primary Hypercholesterolemia Receiving Ongoing Stable Atorvastatin Therapy
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28 Mar 2012 |
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31 Oct 2012 |
470 |
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National Lipid Association recommendations for patient-centered management of dyslipidemia: Part 1 – executive summary
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15 Jul 2014 |
466 |
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Inflammation-related biomarkers in major psychiatric disorders: a cross-disorder assessment of reproducibility and specificity in 43 meta-analyses
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18 Sep 2019 |
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Incidence and mortality trend of congenital heart disease at the global, regional, and national level, 1990–2017
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3 Jun 2020 |
430 |
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Define cancer-associated fibroblasts (CAFs) in the tumor microenvironment: new opportunities in cancer immunotherapy and advances in clinical trials
Hao Zhang, Xinghai Yue, Zhe Chen et al. · Molecular Cancer
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2 Oct 2023 |
425 |
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Causal relationship between gut microbiota and cancers: a two-sample Mendelian randomisation study
Yiwen Long, Lanhua Tang, Yangying Zhou et al. · BMC Medicine
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21 Feb 2023 |
419 |
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Efficacy and safety of alirocumab in high cardiovascular risk patients with inadequately controlled hypercholesterolaemia on maximally tolerated doses of statins: the ODYSSEY COMBO II randomized controlled trial
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16 Feb 2015 |
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Association Between CYP2C19 Loss-of-Function Allele Status and Efficacy of Clopidogrel for Risk Reduction Among Patients With Minor Stroke or Transient Ischemic Attack
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Tissue macrophages: origin, heterogenity, biological functions, diseases and therapeutic targets
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7 Mar 2025 |
338 |
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Immune evasion in cancer: mechanisms and cutting-edge therapeutic approaches
Muhammad Tufail, Canhua Jiang, Ning Li · Signal Transduction and Targeted Therapy
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30 Jul 2025 |
335 |
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Perioperative Rosuvastatin in Cardiac Surgery
Zhe Zheng, Raja Jayaram, Lixin Jiang et al. · New England Journal of Medicine
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4 May 2016 |
319 |
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Bupropion SR Enhances Weight Loss: A 48‐Week Double‐Blind, Placebo‐ Controlled Trial
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Sample Size Guideline for Correlation Analysis
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10 Mar 2016 |
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circPTN sponges miR-145-5p/miR-330-5p to promote proliferation and stemness in glioma
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11 Sep 2019 |
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Lysyl Oxidase (LOX) Family Members: Rationale and Their Potential as Therapeutic Targets for Liver Fibrosis
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Inflammation in diabetic retinopathy: possible roles in pathogenesis and potential implications for therapy
Guo-Tong Xu, Jingfa Zhang, Lei Tang · Neural Regeneration Research
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27 Oct 2022 |
285 |
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Wnt9a Promotes Renal Fibrosis by Accelerating Cellular Senescence in Tubular Epithelial Cells
Congwei Luo, Shan Yu Zhou, Zhanmei Zhou et al. · Journal of the American Society of Nephrology
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12 Feb 2018 |
283 |
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Clinical determinants for fatality of 44,672 patients with COVID-19
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28 Apr 2020 |
282 |
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Pattern recognition receptors: function, regulation and therapeutic potential
Ruochan Chen, Ju Zou, Jiawang Chen et al. · Signal Transduction and Targeted Therapy
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10 Jul 2025 |
279 |
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Immune checkpoint modulators in cancer immunotherapy: recent advances and emerging concepts
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17 Aug 2022 |
275 |
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Results of the National Cholesterol Education (NCEP) Program Evaluation Project Utilizing Novel E-Technology (NEPTUNE) II Survey and Implications for Treatment Under the Recent NCEP Writing Group Recommendations
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