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Bruton Tyrosine Kinase Inhibitor Ibrutinib (PCI-32765) Has Significant Activity in Patients With Relapsed/Refractory B-Cell Malignancies
Ranjana H. Advani, Joseph J. Buggy, Jeff Porter Sharman et al. · Journal of Clinical Oncology
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9 Oct 2012 |
1,129 |
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Neratinib after trastuzumab-based adjuvant therapy in patients with HER2-positive breast cancer (ExteNET): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial
Arlene Chan et al. · The Lancet Oncology
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12 Feb 2016 |
569 |
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Combination Dabrafenib and Trametinib Versus Combination Nivolumab and Ipilimumab for Patients With Advanced BRAF-Mutant Melanoma: The DREAMseq Trial—ECOG-ACRIN EA6134
Michael B. Atkins et al. · Journal of Clinical Oncology
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27 Sep 2022 |
474 |
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IDH1 mutant malignant astrocytomas are more amenable to surgical resection and have a survival benefit associated with maximal surgical resection
Jason Beiko, Dima Suki, Kenneth R. Hess et al. · Neuro-Oncology
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4 Dec 2013 |
470 |
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Management of Metastatic Clear Cell Renal Cell Carcinoma: ASCO Guideline
W. Kimryn Rathmell, R. Bryan Rumble, Peter J. Van Veldhuizen et al. · Journal of Clinical Oncology
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21 Jun 2022 |
351 |
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Neoadjuvant Cemiplimab for Stage II to IV Cutaneous Squamous-Cell Carcinoma
Neil D. Gross et al. · New England Journal of Medicine
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12 Sep 2022 |
334 |
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Preliminary evidence for biologic activity of toceranib phosphate (Palladia®) in solid tumours
Cheryl A. London et al. · Veterinary and Comparative Oncology
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Jun 2011 |
231 |
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Collagen I Promotes Metastasis in Pancreatic Cancer by Activating c-Jun NH2-Terminal Kinase 1 and Up-regulating N-Cadherin Expression
Yasushi Shintani, Michael Anthony Hollingsworth, Margaret J. Wheelock et al. · Cancer Research
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15 Dec 2006 |
230 |
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Randomized Phase II Study of Bevacizumab in Combination With Chemotherapy in Previously Untreated Extensive-Stage Small-Cell Lung Cancer: Results From the SALUTE Trial
David Robert Spigel, P. Townley, David Michael Waterhouse et al. · Journal of Clinical Oncology
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19 Apr 2011 |
227 |
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American Society of Hematology/American Society of Clinical Oncology clinical practice guideline update on the use of epoetin and darbepoetin in adult patients with cancer
J. Douglas Rizzo, Melissa C. Brouwers, Patricia A. Hurley et al. · Blood
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26 Oct 2010 |
207 |
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5-Lipoxygenase and Leukotriene B4 Receptor Are Expressed in Human Pancreatic Cancers But Not in Pancreatic Ducts in Normal Tissue
René Hennig, Xianzhong Ding, Weigang Tong et al. · American Journal Of Pathology
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Aug 2002 |
190 |
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Hereditary nonpolyposis colorectal cancer (lynch syndromes I and II). II. Biomarker studies
Henry T. Lynch, Guy S. Schuelke, William J. Kimberling et al. · Cancer
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15 Aug 1985 |
169 |
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Dual checkpoint targeting of B7-H3 and PD-1 with enoblituzumab and pembrolizumab in advanced solid tumors: interim results from a multicenter phase I/II trial
Charu Aggarwal et al. · Journal for ImmunoTherapy of Cancer
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Apr 2022 |
151 |
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TRANSFORMER: A Randomized Phase II Study Comparing Bipolar Androgen Therapy Versus Enzalutamide in Asymptomatic Men With Castration-Resistant Metastatic Prostate Cancer
Samuel Ray Denmeade et al. · Journal of Clinical Oncology
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22 Feb 2021 |
144 |
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Phase 2 study of dasatinib in patients with alveolar soft part sarcoma, chondrosarcoma, chordoma, epithelioid sarcoma, or solitary fibrous tumor
Scott M. Schuetze, Vanessa Bolejack, Edwin Choy et al. · Cancer
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3 Oct 2016 |
138 |
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Sunitinib Plus Paclitaxel Versus Bevacizumab Plus Paclitaxel for First-Line Treatment of Patients With Advanced Breast Cancer: A Phase III, Randomized, Open-Label Trial
Nicholas J. Robert, Mansoor Noorali Saleh, Devchand Paul et al. · Clinical Breast Cancer
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Apr 2011 |
119 |
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Regorafenib plus nivolumab in patients with mismatch repair-proficient/microsatellite stable metastatic colorectal cancer: a single-arm, open-label, multicentre phase 2 study
Marwan Fakih et al. · EClinicalMedicine
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Apr 2023 |
114 |
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Phase 2 Trial of Gemcitabine, Cisplatin, plus Ipilimumab in Patients with Metastatic Urothelial Cancer and Impact of DNA Damage Response Gene Mutations on Outcomes
Matthew D. Galsky et al. · European Urology
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13 Dec 2017 |
114 |
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Neoadjuvant cemiplimab and surgery for stage II–IV cutaneous squamous-cell carcinoma: follow-up and survival outcomes of a single-arm, multicentre, phase 2 study
Neil D. Gross et al. · The Lancet Oncology
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21 Oct 2023 |
109 |
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Safety and Efficacy of Nivolumab in Patients With Advanced Non–Clear Cell Renal Cell Carcinoma: Results From the Phase IIIb/IV CheckMate 374 Study
Nicholas J. Vogelzang et al. · Clinical Genitourinary Cancer
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16 May 2020 |
107 |
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Contemporary experience with high-dose interleukin-2 therapy and impact on survival in patients with metastatic melanoma and metastatic renal cell carcinoma
Ajjai Shivaram Alva et al. · Cancer Immunology Immunotherapy
Open access |
6 Oct 2016 |
105 |
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Facilitation of radiotherapeutic error by computerized record and verify systems
Gregory Patton, David K. Gaffney, John Moeller · International Journal of Radiation Oncology*Biology*Physics
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23 Apr 2003 |
103 |
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Androgen receptor mutations in patients with castration-resistant prostate cancer treated with apalutamide
Dana E. Rathkopf et al. · Annals of Oncology
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Jun 2017 |
100 |
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Comprehensive molecular profiling of multiple myeloma identifies refined copy number and expression subtypes
Sheri Skerget et al. · Nature Genetics
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19 Aug 2024 |
94 |
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Replication protein A, the laxative that keeps DNA regular: The importance of RPA phosphorylation in maintaining genome stability
Brendan M. Byrne, Greg G. Oakley · Seminars in Cell and Developmental Biology
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13 Nov 2018 |
91 |
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Safety and Antitumor Activity of Apalutamide (ARN-509) in Metastatic Castration-Resistant Prostate Cancer with and without Prior Abiraterone Acetate and Prednisone
Dana E. Rathkopf, Emmanuel S. Antonarakis, Neal D. Shore et al. · Clinical Cancer Research
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17 Feb 2017 |
86 |
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Randomized phase 2 study of obinutuzumab monotherapy in symptomatic, previously untreated chronic lymphocytic leukemia
John C. Byrd, Joseph Michael Flynn, Thomas J. Kipps et al. · Blood
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16 Oct 2015 |
86 |
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Pembrolizumab and platinum-based chemotherapy as first-line therapy for advanced non–small-cell lung cancer: Phase 1 cohorts from the KEYNOTE-021 study
Shirish M. Gadgeel, James P. Stevenson, Corey Jay Langer et al. · Lung Cancer
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25 Aug 2018 |
84 |
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Adjuvant Cemiplimab or Placebo in High-Risk Cutaneous Squamous-Cell Carcinoma
Danny Rischin et al. · New England Journal of Medicine
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31 May 2025 |
82 |
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Comparison of outcomes of transplantation and resection in patients with early hepatocellular carcinoma: a meta-analysis
Mashaal Dhir, ELIZABETH R. LYDEN, Lynette M. Smith et al. · HPB
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19 Jun 2012 |
81 |
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Identification of a Novel, Recurrent SLC44A1‐PRKCA Fusion in Papillary Glioneuronal Tumor
Julia A. Bridge, Xiao‐qiong Liu, János Sümegi et al. · Brain Pathology
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22 Jun 2012 |
81 |
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A phase 1 trial of SGN-CD70A in patients with CD70-positive diffuse large B cell lymphoma and mantle cell lymphoma
Tycel Jovelle Phillips, Paul M. Barr, Steven I. Park et al. · Investigational New Drugs
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22 Aug 2018 |
78 |
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Results of a phase 2 study of bortezomib in patients with relapsed or refractory indolent lymphoma
Nicholas Di Bella, Raymond Taetle, Kathryn S. Kolibaba et al. · Blood
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20 Nov 2009 |
77 |
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A Phase II Trial of the CD40 Agonistic Antibody Sotigalimab (APX005M) in Combination with Nivolumab in Subjects with Metastatic Melanoma with Confirmed Disease Progression on Anti-PD-1 Therapy
Sarah Ann Weiss, Mario Sznol, Montaser F. Shaheen et al. · Clinical Cancer Research
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3 Aug 2023 |
73 |
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Survival trends in mantle cell lymphoma in the United States over 16 years 1992–2007
Rekha Chandran, Stuart K. Gardiner, M. Simon et al. · Leukemia & lymphoma/Leukemia and lymphoma
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13 Jan 2012 |
72 |
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DaxibotulinumtoxinA for Injection has a prolonged duration of response in the treatment of glabellar lines: Pooled data from two multicenter, randomized, double-blind, placebo-controlled, phase 3 studies (SAKURA 1 and SAKURA 2)
Vince Bertucci, Nowell J. Solish, Joely Kaufman‐Janette et al. · Journal of the American Academy of Dermatology
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29 Nov 2019 |
70 |
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Phase 1/2 study of cyclin-dependent kinase (CDK)4/6 inhibitor palbociclib (PD-0332991) with bortezomib and dexamethasone in relapsed/refractory multiple myeloma
Rubén Niesvizky et al. · Leukemia & lymphoma/Leukemia and lymphoma
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27 Mar 2015 |
66 |
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Can pregabalin prevent paclitaxel-associated neuropathy?—An ACCRU pilot trial
Shivani S. Shinde, Drew K. Seisler, Gamini S. Soori et al. · Supportive Care in Cancer
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8 Jul 2015 |
65 |
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Azacitidine favorably modulates PSA kinetics correlating with plasma DNA LINE-1 hypomethylation in men with chemonaïve castration-resistant prostate cancer
Guru Sonpavde, Ana Maria Aparicio, Feng Zhan et al. · Urologic Oncology Seminars and Original Investigations
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7 Dec 2009 |
64 |
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Genomic Landscape of Angiosarcoma: A Targeted and Immunotherapy Biomarker Analysis
Andrea P. Espejo Freire, Andrew Elliott, Andrew Eric Rosenberg et al. · Cancers
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26 Sep 2021 |
61 |
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Clavicular Fractures Following Coracoclavicular Ligament Reconstruction with Tendon Graft
Kimberly A. Turman, Chealon D. Miller, Mark D. Miller · Journal of Bone and Joint Surgery
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Jun 2010 |
59 |
| 42 |
A Randomized, Phase 2 Trial of Docetaxel with or without PX-866, an Irreversible Oral Phosphatidylinositol 3-Kinase Inhibitor, in Patients with Relapsed or Metastatic Non–Small-Cell Lung Cancer
Benjamin Philip Levy, Alexander I. Spira, Daniel Jacob Becker et al. · Journal of Thoracic Oncology
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12 Jun 2014 |
53 |
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Holy Basil leaf extract decreases tumorigenicity and metastasis of aggressive human pancreatic cancer cells in vitro and in vivo: Potential role in therapy
Tomohiro Shimizu, María P. Torres, Subhankar Chakraborty et al. · Cancer Letters
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21 Mar 2013 |
49 |
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The Btk Inhibitor, PCI-32765, Induces Durable Responses with Minimal Toxicity In Patients with Relapsed/Refractory B-Cell Malignancies: Results From a Phase I Study
Nathan Hale Fowler, Jeff Porte Sharman, Sonali M. Smith et al. · Blood
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19 Nov 2010 |
48 |
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Overall survival by clinical risk category for high dose interleukin-2 (HD IL-2) treated patients with metastatic renal cell cancer (mRCC): data from the PROCLAIMSM registry
Mayer Fishman, Janice P. Dutcher, Joseph I. Clark et al. · Journal for ImmunoTherapy of Cancer
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27 Mar 2019 |
47 |
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LBA6 Phase III trial of [177Lu]Lu-PSMA-617 combined with ADT + ARPI in patients with PSMA-positive metastatic hormone-sensitive prostate cancer (PSMAddition)
S.T. Tagawa, O. Sartor, J.M. Piulats et al. · Annals of Oncology
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Sep 2025 |
45 |
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Incidence and Prognostic Significance of Second Primary Cancers in Renal Cell Carcinoma
Subhankar Chakraborty, Stefano Tarantolo, Surinder K. Batra et al. · American Journal of Clinical Oncology
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22 Mar 2012 |
44 |
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Chemotherapy options in castration-resistant prostate cancer
R. Hauke, Benjamin A. Teply · Indian Journal of Urology
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2016 |
42 |
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A Randomized, Phase II Trial of Cetuximab With or Without PX-866, an Irreversible Oral Phosphatidylinositol 3-Kinase Inhibitor, in Patients With Metastatic Colorectal Carcinoma
Daniel W. Bowles, Mark D. Kochenderfer, Allen Lee Cohn et al. · Clinical Colorectal Cancer
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Apr 2016 |
42 |
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An Open-label, Single-arm, Phase 2 Trial of Panitumumab Plus FOLFIRI as Second-line Therapy in Patients with Metastatic Colorectal Cancer
Allen Lee Cohn, Grace Shumaker, Pankaj Khandelwal et al. · Clinical Colorectal Cancer
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26 May 2011 |
40 |