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Most cited papers from New York Structural Biology Center

What are the most cited papers from New York Structural Biology Center?

The most cited paper from New York Structural Biology Center is "CSF-1R inhibition alters macrophage polarization and blocks glioma progression" (Stephanie M. Pyonteck, Leila Akkari, Alberto J. Schuhmacher et al., 2013), with 2,544 citations. Next come "Positive-unlabeled convolutional neural networks for particle picking in cryo-electron micrographs" (1,871) and "Structures of Human Acetylcholinesterase in Complex with Pharmacologically Important Ligands" (1,365).

Showing 50 of 60 papers. Every paper with more than 188 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 CSF-1R inhibition alters macrophage polarization and blocks glioma progression Stephanie M. Pyonteck, Leila Akkari, Alberto J. Schuhmacher et al. · Nature Medicine Open access 22 Sep 2013 2,544
2 Positive-unlabeled convolutional neural networks for particle picking in cryo-electron micrographs Tristan Bepler, Andrew Morin, Micah Rapp et al. · Nature Methods Open access 7 Oct 2019 1,871
3 Structures of Human Acetylcholinesterase in Complex with Pharmacologically Important Ligands Jonah Cheung, Michael J. Rudolph, Fiana Burshteyn et al. · Journal of Medicinal Chemistry 4 Oct 2012 1,365
4 Addressing preferred specimen orientation in single-particle cryo-EM through tilting Yong Zi Tan, Philip Rupert Baldwin, Joseph H. Davis et al. · Nature Methods Open access 3 Jul 2017 1,069
5 Structural and immunologic characterization of bovine, horse, and rabbit serum albumins Karolina A. Majorek, Przemyslaw Jerzy Porebski, Arjun Dayal et al. · Molecular Immunology Open access 6 Jun 2012 980
6 Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs Thórdur Óskarsson, Swarnali Acharyya, Xiang H.-F. Zhang et al. · Nature Medicine Open access 26 Jun 2011 881
7 Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser Yanyong Kang et al. · Nature Open access 22 Jul 2015 845
8 Topaz-Denoise: general deep denoising models for cryoEM and cryoET Tristan Bepler, Kotaro Kelley, Alex J. Noble et al. · Nature Communications Open access 15 Oct 2020 640
9 PredictProtein—an open resource for online prediction of protein structural and functional features Guy Yachdav, Edda Kloppmann, László Kaján et al. · Nucleic Acids Research Open access 5 May 2014 631
10 Molecular Architecture of the Human Pre-mRNA 3′ Processing Complex Yongsheng Shi, Dafne Campigli Di Giammartino, Derek J. Taylor et al. · Molecular Cell Open access Feb 2009 580
11 Learning the protein language: Evolution, structure, and function Tristan Bepler, Bonnie Berger · Cell Systems Open access Jun 2021 553
12 Structure of the agonist-bound neurotensin receptor Jim F. White, Nicholas Noinaj, Yoko Shibata et al. · Nature Open access 9 Oct 2012 514
13 The IL-6/JAK/Stat3 Feed-Forward Loop Drives Tumorigenesis and Metastasis Qing Chang et al. · Neoplasia Open access Jul 2013 514
14 Structural Basis for Helicase-Polymerase Coupling in the SARS-CoV-2 Replication-Transcription Complex James Chen, Brandon F. Malone, Eliza Llewellyn et al. · Cell Open access 28 Jul 2020 512
15 ER-mitochondria tethering by PDZD8 regulates Ca 2+ dynamics in mammalian neurons Yusuke Hirabayashi, Seok‐Kyu Kwon, Hunki Paek et al. · Science Open access 2 Nov 2017 507
16 α-Klotho is a non-enzymatic molecular scaffold for FGF23 hormone signalling Gaozhi Chen, Liu Yang, Regina M. Goetz et al. · Nature Open access 2018 499
17 Codon influence on protein expression in E. coli correlates with mRNA levels Grégory Boël, Reka R. Letso, H. Neely et al. · Nature Open access 12 Jan 2016 488
18 Perspectives on NMR in drug discovery: a technique comes of age Maurizio Pellecchia, Ivano Bertini, David Cowburn et al. · Nature Reviews Drug Discovery ReviewOpen access 26 Aug 2008 419
19 Analysing Six Types of Protein–Protein Interfaces Yanay Ofran, Burkhard Rost · Journal of Molecular Biology 27 Dec 2002 415
20 Polarized release of T-cell-receptor-enriched microvesicles at the immunological synapse Kaushik Choudhuri, Jaime Llodrá, Eric W. Roth et al. · Nature Open access 31 Jan 2014 403
21 Characterization and engineering of the bifunctional N - and O -glucosyltransferase involved in xenobiotic metabolism in plants Melissa Brazier‐Hicks, Wendy A. Offen, Markus C. Gershater et al. · Proceedings of the National Academy of Sciences Open access 12 Dec 2007 322
22 Structure of a DNA-bound Ultrabithorax–Extradenticle homeodomain complex Jonathan M. Passner, Hyung Don Ryoo, Leyi Shen et al. · Nature Feb 1999 321
23 Routine single particle CryoEM sample and grid characterization by tomography Alex J. Noble et al. · eLife Open access 29 May 2018 320
24 Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1 Kai Y. Xu et al. · Nature Medicine Open access 29 May 2018 313
25 Expression system for structural and functional studies of human glycosylation enzymes Kelley W. Moremen et al. · Nature Chemical Biology Open access 18 Dec 2017 312
26 3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV–infected mice Athri D. Rathnayake, Jian Hua Zheng, Yunjeong Kim et al. · Science Translational Medicine Open access 3 Aug 2020 296
27 Mimicking Cellular Sorting Improves Prediction of Subcellular Localization Rajesh Parameshwaran Nair, Burkhard Rost · Journal of Molecular Biology 8 Mar 2005 294
28 Structures of Human Acetylcholinesterase Bound to Dihydrotanshinone I and Territrem B Show Peripheral Site Flexibility Jonah Cheung, Ebony Nicole Gary, Kazuro Shiomi et al. · ACS Medicinal Chemistry Letters Open access 23 Sep 2013 293
29 The AKT-mTOR pathway plays a critical role in the development of leiomyosarcomas Eva Hernando, Elizabeth Charytonowicz, Maria E. Dudas et al. · Nature Medicine 13 May 2007 291
30 Ultrastructural analysis of hepatitis C virus particles Maria Teresa Catanese, Kunihiro Uryu, Martina Kopp et al. · Proceedings of the National Academy of Sciences Open access 20 May 2013 287
31 A Small Molecule RAS-Mimetic Disrupts RAS Association with Effector Proteins to Block Signaling Sai Krishna Athaluri Divakar, Rodrigo Vasquez‐Del Carpio, Kaushik Dutta et al. · Cell Open access Apr 2016 282
32 SNAP predicts effect of mutations on protein function Yana Bromberg, Guy Yachdav, Burkhard Rost · Bioinformatics Open access 30 Aug 2008 281
33 Structure of the insulin receptor–insulin complex by single-particle cryo-EM analysis Giovanna Scapin, Venkata P. Dandey, Zhening Zhang et al. · Nature Open access 28 Feb 2018 279
34 Automatic prediction of protein function Kazimierz O. Wrzeszczyński, Y. Ofran, Burkhard Rost et al. · Cellular and Molecular Life Sciences Open access Dec 2003 279
35 ISIS: interaction sites identified from sequence Yanay Ofran, Burkhard Rost · Bioinformatics Open access 15 Jan 2007 270
36 Protein–Protein Interaction Hotspots Carved into Sequences Yanay Ofran, Burkhard Rost · PLoS Computational Biology Open access 5 Jul 2007 263
37 Predicted protein–protein interaction sites from local sequence information Yanay Ofran, Burkhard Rost · FEBS Letters 14 May 2003 262
38 Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP Ruifeng Qi, Evans Boateng Sarbeng, Qun Liu et al. · Nature Structural & Molecular Biology Open access 26 May 2013 258
39 Cardiolipin Affects the Supramolecular Organization of ATP Synthase in Mitochondria Devrim Acehan, Ashim Malhotra, Yang Xu et al. · Biophysical Journal Open access May 2011 257
40 Improved molecular replacement by density- and energy-guided protein structure optimization Frank DiMaio, Thomas C. Terwilliger, Randy J. Read et al. · Nature Open access 28 Apr 2011 252
41 Bestrophin 1 and retinal disease Adiv A. Johnson, Karina E Guziewicz, C. Justin Lee et al. · Progress in Retinal and Eye Research Open access 30 Jan 2017 249
42 Modular Assembly of the Bacterial Large Ribosomal Subunit Joseph H. Davis, Yong Zi Tan, Bridget O Carragher et al. · Cell Open access Dec 2016 244
43 FACT caught in the act of manipulating the nucleosome Yang Liu, Keda Zhou, Naifu Zhang et al. · Nature Open access 27 Nov 2019 243
44 Reducing effects of particle adsorption to the air–water interface in cryo-EM Alex J. Noble, Hui Alex Wei, Venkata P. Dandey et al. · Nature Methods Open access 17 Sep 2018 240
45 Untangling Desmosomal Knots with Electron Tomography Wanzhong He, Pamela Cowin, David L. Stokes · Science 2 Oct 2003 237
46 Crystal structures of catalytic complexes of the oxidative DNA/RNA repair enzyme AlkB Bomina Yu, William C. Edstrom, Jordi Benach et al. · Nature Feb 2006 237
47 Structure of an endosomal signaling GPCR–G protein–β-arrestin megacomplex Anthony H. Nguyen et al. · Nature Structural & Molecular Biology Open access 18 Nov 2019 234
48 The structural basis of cyclic diguanylate signal transduction by PilZ domains Jordi Benach, Swarup S. Swaminathan, Rita Tamayo et al. · The EMBO Journal Open access 22 Nov 2007 230
49 A Cell-penetrating Helical Peptide as a Potential HIV-1 Inhibitor Hongtao Zhang, Qian Cheng Zhao, Shibani Bhattacharya et al. · Journal of Molecular Biology Open access 7 Mar 2008 216
50 Structure and drug resistance of the Plasmodium falciparum transporter PfCRT Jonathan Kim, Yong Zi Tan, Kathryn J. Wicht et al. · Nature Open access 27 Nov 2019 212

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.