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Institution · Ocular Surface Center

Most cited papers from Ocular Surface Center

What are the most cited papers from Ocular Surface Center?

The most cited paper from Ocular Surface Center is "Pro- and anti-inflammatory forms of interleukin-1 in the tear fluid and conjunctiva of patients with dry-eye disease." (Abraham Solomon, Dilek Dursun, Zhihong Liu et al., 2001), with 731 citations. Next come "Amniotic Membrane Transplantation for Persistent Epithelial Defects With Ulceration" (721) and "Use of Tissue-Type Plasminogen Activator for Acute Ischemic Stroke" (659).

Showing 50 of 60 papers. Every paper with more than 199 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Pro- and anti-inflammatory forms of interleukin-1 in the tear fluid and conjunctiva of patients with dry-eye disease. Abraham Solomon, Dilek Dursun, Zhihong Liu et al. · PubMed Sep 2001 731
2 Amniotic Membrane Transplantation for Persistent Epithelial Defects With Ulceration Shwu‐Huey Lee, Scheffer C.G. Tseng · American Journal of Ophthalmology Open access Mar 1997 721
3 Use of Tissue-Type Plasminogen Activator for Acute Ischemic Stroke Irene L. Katzan, Anthony J. Furlan, Lynne E. Lloyd et al. · JAMA Mar 2000 659
4 Altered cytokine balance in the tear fluid and conjunctiva of patients with Sjögren's syndrome keratoconjunctivitis sicca Stephen C. Pflugfelder, David Jones, Zhonghua Ji et al. · Current Eye Research 1999 615
5 Comparison of Conjunctival Autografts, Amniotic Membrane Grafts, and Primary Closure for Pterygium Excision Pinnita Prabhasawat, Keith Barton, Gene Burkett et al. · Ophthalmology Open access Jun 1997 604
6 Experimental Dry Eye Stimulates Production of Inflammatory Cytokines and MMP-9 and Activates MAPK Signaling Pathways on the Ocular Surface Lihui Luo, De‐Quan Li, Amish H. Doshi et al. · Investigative Ophthalmology & Visual Science 22 Nov 2004 598
7 Tear Cytokine Profiles in Dysfunctional Tear Syndrome Helene Y Lam, Lauren Bleiden, Cintia Sade de Paiva et al. · American Journal of Ophthalmology Open access 10 Nov 2008 498
8 Cytologlogic Evidence of Corneal Diseases with Limbal Stem Cell Deficiency Vilavun Puangsricharern, Scheffer C.G. Tseng · Ophthalmology Open access Oct 1995 494
9 Suppression of transforming growth factor-beta isoforms, TGF-? receptor type II, and myofibroblast differentiation in cultured human corneal and limbal fibroblasts by amniotic membrane matrix Scheffer C.G. Tseng, De-Quan Li, Xiang Ma · Journal of Cellular Physiology Jun 1999 488
10 Amniotic Membrane Transplantation for Conjunctival Surface Reconstruction Scheffer C.G. Tseng, Pinnita Prabhasawat, Shwu‐Huey Lee · American Journal of Ophthalmology Open access Dec 1997 453
11 IL-17 disrupts corneal barrier following desiccating stress Cintia Sade de Paiva, Suksri Chotikavanich, Solherny B. Pangelinan et al. · Mucosal Immunology Open access 25 Feb 2009 425
12 Characterization of Putative Stem Cell Phenotype in Human Limbal Epithelia Zhuo Chen, Cintia Sade de Paiva, Lihui Luo et al. · Stem Cells Open access May 2004 424
13 Amniotic membrane transplantation for acute chemical or thermal burns Daniel Meller, Renato T. F. Pires, Robert J. Mack et al. · Ophthalmology May 2000 423
14 Antiinflammatory therapy for dry eye Stephen Carl Pflugfelder · American Journal of Ophthalmology Feb 2004 422
15 Broad H3K4me3 is associated with increased transcription elongation and enhancer activity at tumor-suppressor genes Kaifu Chen, Zhong Chen, Dayong Wu et al. · Nature Genetics Open access 24 Aug 2015 404
16 Production and Activity of Matrix Metalloproteinase-9 on the Ocular Surface Increase in Dysfunctional Tear Syndrome Suksri Chotikavanich, Cintia Sade de Paiva, De Quan Li et al. · Investigative Ophthalmology & Visual Science Open access 23 Jun 2009 400
17 Stimulation of Matrix Metalloproteinases by Hyperosmolarity via a JNK Pathway in Human Corneal Epithelial Cells De‐Quan Li, Zhuo Chen, Xiu Jun Song et al. · Investigative Ophthalmology & Visual Science 22 Nov 2004 392
18 The Diagnosis and Management of Dry Eye Stephen Carl Pflugfelder, Abraham Solomon, Michael Ethan Stern · Cornea Sep 2000 363
19 Topical nonpreserved methylprednisolone therapy for keratoconjunctivitis sicca in Sjögren syndrome P J Marsh, Stephen C. Pflugfelder · Ophthalmology Open access Apr 1999 358
20 Dry Eye as a Mucosal Autoimmune Disease Michael Ethan Stern, Chris S. Schaumburg, Stephen Carl Pflugfelder · International Reviews of Immunology Open access 13 Jan 2013 348
21 JNK and ERK MAP kinases mediate induction of IL-1β, TNF-α and IL-8 following hyperosmolar stress in human limbal epithelial cells De‐Quan Li, Lihui Luo, Zhuo Chen et al. · Experimental Eye Research Open access 4 Oct 2005 347
22 Pathogenic role of Demodex mites in blepharitis Jingbo Liu, Hosam Sheha, Scheffer C.G. Tseng · Current Opinion in Allergy and Clinical Immunology Open access 4 Aug 2010 346
23 Corneal epithelial stem cells at the limbus: looking at some old problems from a new angle Robert M. Lavker, Scheffer C.G. Tseng, Tung‐Tien Sun · Experimental Eye Research 20 Nov 2003 341
24 Hyperosmolar Saline Is a Proinflammatory Stress on the Mouse Ocular Surface Lihui Luo, De‐Quan Li, Rosa M. Corrales et al. · Eye & Contact Lens Science & Clinical Practice Sep 2005 340
25 Inflammatory macrophage migration requires MMP-9 activation by plasminogen in mice Yanqing Gong, Erika Hart, Aleksey Shchurin et al. · Journal of Clinical Investigation Open access Aug 2008 335
26 Matrix Metalloproteinase-9 Knockout Confers Resistance to Corneal Epithelial Barrier Disruption in Experimental Dry Eye Stephen Carl Pflugfelder, William J. Farley, Lihui Luo et al. · American Journal Of Pathology Open access 2005 331
27 Dry Eye–Induced Conjunctival Epithelial Squamous Metaplasia Is Modulated by Interferon-γ Cintia Sade de Paiva, Arturo Villarreal, Rosa M. Corrales et al. · Investigative Ophthalmology & Visual Science 25 May 2007 324
28 ABCG2 Transporter Identifies a Population of Clonogenic Human Limbal Epithelial Cells Cintia Sade de Paiva, Zhuo Chen, Rosa M. Corrales et al. · Stem Cells Open access 2005 318
29 How Does Amniotic Membrane Work? Scheffer C.G. Tseng, Edgar M. Espana, Tetsuya Kawakita et al. · The Ocular Surface Jul 2004 315
30 Niche regulation of corneal epithelial stem cells at the limbus Wei Shan Li, Yasutaka Hayashida, Ying‐Ting Chen et al. · Cell Research Open access 2007 314
31 Apoptosis of Ocular Surface Cells in Experimentally Induced Dry Eye Steven Yeh, Xiu Jun Song, William J. Farley et al. · Investigative Ophthalmology & Visual Science 2003 306
32 Suppression of interleukin 1alpha and interleukin 1beta in human limbal epithelial cells cultured on the amniotic membrane stromal matrix Abraham Solomon · British Journal of Ophthalmology Open access Apr 2001 291
33 Suppression of TGF-ß signaling in both normal conjunctival fibroblasts and pterygial body fibroblasts by amniotic membrane Sao-Bing Lee, De‐Quan Li, Donald T.H. Tan et al. · Current Eye Research 2000 290
34 Utilization of Intravenous Tissue Plasminogen Activator for Acute Ischemic Stroke Irene L. Katzan, Maxim D. Hammer, Eric D. Hixson et al. · Archives of Neurology Mar 2004 290
35 Amniotic membrane transplantation after extensive removal of primary and recurrent pterygia Abraham Solomon, Renato T. F. Pires, Scheffer C.G. Tseng · Ophthalmology Mar 2001 288
36 Amniotic membrane transplantation for severe neurotrophic corneal ulcers H.-J. Chen · British Journal of Ophthalmology Open access Aug 2000 279
37 Ex vivo expansion of limbal epithelial stem cells: amniotic membrane serving as a stem cell niche Martin Grueterich, Edgar M. Espana, Scheffer C.G. Tseng · Survey of Ophthalmology Nov 2003 277
38 Tear fluid gelatinase B activity correlates with IL-1alpha concentration and fluorescein clearance in ocular rosacea. Adolfo A Afonso, Lucia Sobrin, Dagoberto C. Monroy et al. · PubMed Oct 1999 271
39 Evaluation of corneal thickness and topography in normal eyes using the Orbscan corneal topography system Zhenzhen Liu, Andrew Huang, Stephen Carl Pflugfelder · British Journal of Ophthalmology Open access Jul 1999 264
40 Rethinking Dry Eye Disease: A Perspective on Clinical Implications Anthony J. Bron, Alan Tomlinson, Gary N. Foulks et al. · The Ocular Surface 13 Feb 2014 259
41 A mouse model of keratoconjunctivitis sicca. Dilek Dursun, Min Wang, Dagoberto C. Monroy et al. · PubMed Mar 2002 258
42 High Prevalence ofDemodexin Eyelashes with Cylindrical Dandruff Yingying Gao, Mario A. Di Pascuale, Wei Shan Li et al. · Investigative Ophthalmology & Visual Science 25 Aug 2005 247
43 Correlation of Goblet Cell Density and Mucosal Epithelial Membrane Mucin Expression with Rose Bengal Staining in Patients with Ocular Irritation Stephen Carl Pflugfelder, Scheffer C.G. Tseng, Kenichi Yoshino et al. · Ophthalmology Open access Feb 1997 245
44 Inflammation in Dry Eye Michael Ethan Stern, Stephen Carl Pflugfelder · The Ocular Surface Apr 2004 245
45 Inflammation and the Nervous System: The Connection in the Cornea in Patients with Infectious Keratitis Andrea Cruzat, Deborah Witkin, Neda Baniasadi et al. · Investigative Ophthalmology & Visual Science Open access 2 Apr 2011 243
46 Treatment of recalcitrant recurrent corneal erosions with inhibitors of matrix metalloproteinase-9, doxycycline and corticosteroids Dilek Dursun, Michael C Kim, Abraham Solomon et al. · American Journal of Ophthalmology Jul 2001 240
47 A randomized, double-masked, placebo-controlled, multicenter comparison of loteprednol etabonate ophthalmic suspension, 0.5%, and placebo for treatment of keratoconjunctivitis sicca in patients with delayed tear clearance Stephen Carl Pflugfelder, Steven L. Maskin, Bruce D. Anderson et al. · American Journal of Ophthalmology Sep 2004 233
48 Acute and Chronic Ophthalmic Involvement in Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis – A Comprehensive Review and Guide to Therapy. II. Ophthalmic Disease Sahar Kohanim et al. · The Ocular Surface 14 Feb 2016 224
49 Phenotypic characterization of human corneal epithelial cells expanded ex vivo from limbal explant and single cell cultures Hyun Seung Kim, Xiu Jun Song, Cintia Sade de Paiva et al. · Experimental Eye Research Open access 3 Apr 2004 214
50 Amniotic membrane transplantation for partial limbal stem cell deficiency David F. Anderson · British Journal of Ophthalmology Open access May 2001 213

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.