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Impact of Dual Lipid-Lowering Strategy With Ezetimibe and Atorvastatin on Coronary Plaque Regression in Patients With Percutaneous Coronary Intervention
Kenichi Tsujita et al. · Journal of the American College of Cardiology
Open access |
27 Jul 2015 |
456 |
| 2 |
Growth differentiation factor 15 as a useful biomarker for mitochondrial disorders
Shuichi Yatsuga, Yasunori Fujita, Akiko Ishii et al. · Annals of Neurology
Open access |
14 Oct 2015 |
299 |
| 3 |
Practical Guidance for the Evaluation and Management of Drug Hypersensitivity: Specific Drugs
Ana Dioun Broyles et al. · The Journal of Allergy and Clinical Immunology In Practice
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Oct 2020 |
232 |
| 4 |
HLA‐B*1511 is a risk factor for carbamazepine‐induced Stevens‐Johnson syndrome and toxic epidermal necrolysis in Japanese patients
Nahoko Kaniwa, Yoshiro Saito, Michiko Aihara et al. · Epilepsia
Open access |
3 Nov 2010 |
229 |
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Evaluation of Urinary 8-Hydroxydeoxy-Guanosine as a Novel Biomarker of Macrovascular Complications in Type 2 Diabetes
Takeshi Nishikawa, Takayuki Sasahara, Shinsuke Kiritoshi et al. · Diabetes Care
Open access |
May 2003 |
194 |
| 6 |
A whole-genome association study of major determinants for allopurinol-related Stevens–Johnson syndrome and toxic epidermal necrolysis in Japanese patients
Masahiro Tohkin, Nahoko Kaniwa, Yoshiro Saito et al. · The Pharmacogenomics Journal
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13 Sep 2011 |
186 |
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Clinical and Microbiological Differences between Mycobacterium abscessus and Mycobacterium massiliense Lung Diseases
Toshiyuki Harada, Yasushi Akiyama, Atsuyuki Kurashima et al. · Journal of Clinical Microbiology
Open access |
22 Aug 2012 |
176 |
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Effects of cigarette smoke on barrier function and tight junction proteins in the bronchial epithelium: protective role of cathelicidin LL-37
Miyoko Tatsuta, Keiko Kan‐o, Yumiko Ishii et al. · Respiratory Research
Open access |
9 Nov 2019 |
158 |
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Prospective and randomized clinical trial for the treatment of hepatocellular carcinoma ? a comparison of lipiodol-transcatheter arterial embolization with and without Adriamycin (first cooperative study)
Saburo Kawai et al. · Cancer Chemotherapy and Pharmacology
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1992 |
148 |
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Heterozygous deletion of ITPR1, but not SUMF1, in spinocerebellar ataxia type 16
Akiko Iwaki, Yu Kawano, Shiroh Miura et al. · Journal of Medical Genetics
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11 Oct 2007 |
144 |
| 11 |
Quantitation of the Global Right Ventricular Function in Children with Normal Heart and Congenital Heart Disease: A Right Ventricular Myocardial Performance Index
Masahiro Ishii, Genjyu Eto, Chuwa Tei et al. · Pediatric Cardiology
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Sep 2000 |
139 |
| 12 |
Prognostic value of serial serum KL-6 measurements in patients with idiopathic pulmonary fibrosis
Kentaro Wakamatsu, Nobuhiko Nagata, Hiroyuki Kumazoe et al. · Respiratory Investigation
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9 Nov 2016 |
122 |
| 13 |
Reduction rate of body mass index predicts prognosis for survival in amyotrophic lateral sclerosis: A multicenter study in Japan
Toshio Shimizu, Utako Nagaoka, Yuki Nakayama et al. · Amyotrophic Lateral Sclerosis
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28 May 2012 |
115 |
| 14 |
Impaired Food Transportation in Parkinson’s Disease Related to Lingual Bradykinesia
George Umemoto, Yoshio Tsuboi, Akio Kitashima et al. · Dysphagia
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28 Aug 2010 |
111 |
| 15 |
Clinical study of childhood acute disseminated encephalomyelitis, multiple sclerosis, and acute transverse myelitis in Fukuoka Prefecture, Japan
Hiroyuki Torisu et al. · Brain and Development
Open access |
27 Nov 2009 |
109 |
| 16 |
Rapid decrease in forced vital capacity in patients with idiopathic pulmonary upper lobe fibrosis
Kentaro Watanabe, Nobuhiko Nagata, Yasuhiko Kitasato et al. · Respiratory Investigation
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Aug 2012 |
102 |
| 17 |
HPGCD Outperforms HPBCD as a Potential Treatment for Niemann-Pick Disease Type C During Disease Modeling with iPS Cells
Minami Soga, Yoichi Ishitsuka, Makoto Hamasaki et al. · Stem Cells
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19 Dec 2014 |
102 |
| 18 |
Multiple system degeneration with basophilic inclusions in Japanese ALS patients with FUS mutation
Takahisa Tateishi, Toshihiro Hokonohara, Ryo Yamasaki et al. · Acta Neuropathologica
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4 Dec 2009 |
101 |
| 19 |
A unique case of fibrodysplasia ossificans progressiva with an ACVR1 mutation, G356D, other than the common mutation (R206H)
Hirokazu Furuya, Koji Ikezoe, Lixiang Wang et al. · American Journal of Medical Genetics Part A
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17 Jan 2008 |
90 |
| 20 |
The thoracic cage becomes flattened in the progression of pleuroparenchymal fibroelastosis
Taishi Harada, Yūji Yoshida, Yasuhiko Kitasato et al. · European Respiratory Review
Open access |
31 May 2014 |
87 |
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SCA8 RAN polySer protein preferentially accumulates in white matter regions and is regulated by eIF3F
Fatma Ayhan, Barbara A. Perez, Hannah K. Shorrock et al. · The EMBO Journal
Open access |
11 Sep 2018 |
81 |
| 22 |
Clinical Significance of Adverse Events for Patients with Unresectable Hepatocellular Carcinoma Treated with Lenvatinib: A Multicenter Retrospective Study
Shigeo Shimose, Hideki Iwamoto, Takashi Niizeki et al. · Cancers
Open access |
11 Jul 2020 |
79 |
| 23 |
Extensive polymorphisms of LILRB1 (ILT2, LIR1) and their association with HLA-DRB1 shared epitope negative rheumatoid arthritis
Kimiko Kuroki, Naoyuki Tsuchiya, Mitsunori Shiroishi et al. · Human Molecular Genetics
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13 Jul 2005 |
79 |
| 24 |
Pathomorphology of Esophageal and Gastric Varices
Masaaki Arakawa, Takao Masuzaki, Kunio Okuda · Seminars in Liver Disease
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2002 |
78 |
| 25 |
Phase II Trial of Intra-Arterial Chemotherapy using a Novel Lipophilic Platinum Derivative (SM-11355) in Patients with Hepatocellular Carcinoma
Takuji Okusaka, Shuichi Okada, Toshio Nakanishi et al. · Investigational New Drugs
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16 Jan 2004 |
77 |
| 26 |
Clinical features and a mutation with late onset of limb girdle muscular dystrophy 2B
Toshinari Takahashi et al. · Journal of Neurology Neurosurgery & Psychiatry
Open access |
15 Dec 2012 |
76 |
| 27 |
Long-term recovery of exercise capacity and pulmonary function after lobectomy
Yoshinori Nagamatsu, Kanetaka Maeshiro, Norman Y. Kimura et al. · Journal of Thoracic and Cardiovascular Surgery
Open access |
Nov 2007 |
76 |
| 28 |
Specific HLA Types are Associated with Antiepileptic Drug-Induced Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis in Japanese Subjects
Nahoko Kaniwa et al. · Pharmacogenomics
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Nov 2013 |
72 |
| 29 |
Beyond free radical scavenging: Beneficial effects of edaravone (Radicut) in various diseases (Review)
Kiyoshi Kikuchi, Nobuyuki Takeshige, Naoki Miura et al. · Experimental and Therapeutic Medicine
Open access |
20 Sep 2011 |
71 |
| 30 |
Molecular epidemiology and clinical spectrum of hereditary spastic paraplegia in the Japanese population based on comprehensive mutational analyses
Hiroyuki Ishiura, Yuji Takahashi, Toshihiro Hayashi et al. · Journal of Human Genetics
Open access |
23 Jan 2014 |
70 |
| 31 |
FALS with FUS mutation in Japan, with early onset, rapid progress and basophilic inclusion
Naoki Suzuki, Masashi Aoki, Hitoshi Warita et al. · Journal of Human Genetics
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12 Mar 2010 |
70 |
| 32 |
IL-38: A new factor in rheumatoid arthritis
Shinichi Takenaka, Shinjiro Kaieda, Tomotaka Kawayama et al. · Biochemistry and Biophysics Reports
Open access |
30 Oct 2015 |
69 |
| 33 |
Edaravone attenuates cerebral ischemic injury by suppressing aquaporin-4
Kiyoshi Kikuchi et al. · Biochemical and Biophysical Research Communications
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7 Sep 2009 |
68 |
| 34 |
Heterogeneous clinical features in patients with pulmonary fibrosis showing histology of pleuroparenchymal fibroelastosis
Yūji Yoshida, Nobuhiko Nagata, Nobuko Tsuruta et al. · Respiratory Investigation
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29 Dec 2015 |
67 |
| 35 |
A unique mutation of ALK2, G356D, found in a patient with fibrodysplasia ossificans progressiva is a moderately activated BMP type I receptor
Toru Fukuda et al. · Biochemical and Biophysical Research Communications
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25 Oct 2008 |
67 |
| 36 |
Pathologic stage I non–small cell lung cancer with high levels of preoperative serum carcinoembryonic antigen: Clinicopathologic characteristics and prognosis
Haruhisa Matsuguma, Rie Nakahara, Seiji Igarashi et al. · Journal of Thoracic and Cardiovascular Surgery
Open access |
2008 |
65 |
| 37 |
Lenvatinib prolongs the progression‑free survival time of patients with intermediate‑stage hepatocellular carcinoma refractory to transarterial chemoembolization: A multicenter cohort study using data mining analysis
Shigeo Shimose, Takumi Kawaguchi, Masatoshi Tanaka et al. · Oncology Letters
Open access |
19 Jun 2020 |
64 |
| 38 |
Pathogenic Mutation of ALK2 Inhibits Induced Pluripotent Stem Cell Reprogramming and Maintenance: Mechanisms of Reprogramming and Strategy for Drug Identification
Makoto Hamasaki, Yoshinobu Hashizume, Yoshinori Yamada et al. · Stem Cells
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4 Sep 2012 |
64 |
| 39 |
Endoplasmic reticulum stress in myotonic dystrophy type 1 muscle
Koji Ikezoe, Masayuki Nakamori, Hirokazu Furuya et al. · Acta Neuropathologica
Open access |
27 Jul 2007 |
64 |
| 40 |
Prognostic stratification of patients with nasopharyngeal carcinoma based on tumor immune microenvironment
Takeharu Ono, Koichi Azuma, Akihiko Kawahara et al. · Head & Neck
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13 May 2018 |
63 |
| 41 |
Hydrogen Sulfide Production From Cysteine and Homocysteine by Periodontal and Oral Bacteria
Akihiro Yoshida, Mamiko Yoshimura, Naoya Ohara et al. · Journal of Periodontology
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Nov 2009 |
62 |
| 42 |
Establishing diagnostic criteria for Perry syndrome
Takayasu Mishima, Shinsuke Fujioka, Hiroyuki Tomiyama et al. · Journal of Neurology Neurosurgery & Psychiatry
Open access |
31 Oct 2017 |
60 |
| 43 |
Loss of hnRNPA1 in ALS spinal cord motor neurons with TDP ‐43‐positive inclusions
Hiroyuki Honda, Hideomi Hamasaki, Tomihiro Wakamiya et al. · Neuropathology
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22 Oct 2014 |
60 |
| 44 |
Alternating Lenvatinib and Trans-Arterial Therapy Prolongs Overall Survival in Patients with Inter-Mediate Stage HepatoCellular Carcinoma: A Propensity Score Matching Study
Shigeo Shimose, Hideki Iwamoto, Masatoshi Tanaka et al. · Cancers
Open access |
5 Jan 2021 |
57 |
| 45 |
The Japanese Society of Hypertension Guidelines for the management of elevated blood pressure and hypertension 2025 (JSH2025)
Yusuke Ohya et al. · Hypertension Research
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2026 |
56 |
| 46 |
Clinicopathologic Features of Oculopharyngodistal Myopathy WithLRP12CGG Repeat Expansions Compared With Other Oculopharyngodistal Myopathy Subtypes
Theerawat Kumutpongpanich et al. · JAMA Neurology
Open access |
28 May 2021 |
55 |
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Sporadic juvenile amyotrophic lateral sclerosis caused by mutant FUS/TLS: possible association of mental retardation with this mutation
Satoshi Yamashita, Akira S. Mori, Hideya Sakaguchi et al. · Journal of Neurology
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4 Nov 2011 |
55 |
| 48 |
A polymorphism in CCR1/CCR3 is associated with narcolepsy
Hiromi Toyoda et al. · Brain Behavior and Immunity
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15 May 2015 |
54 |
| 49 |
Distal tuberosity osteotomy in open-wedge high tibial osteotomy does not exacerbate patellofemoral osteoarthritis on arthroscopic evaluation
Tomohiro Horikawa, Kenji Kubota, Shintaro Hara et al. · Knee Surgery Sports Traumatology Arthroscopy
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28 Jun 2019 |
53 |
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“Reversed Halo Sign” of High-resolution Computed Tomography in Pulmonary Sarcoidosis
Hiroyuki Kumazoe, Kazuko Matsunaga, Nobuhiko Nagata et al. · Journal of Thoracic Imaging
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Feb 2009 |
53 |