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Most cited papers from Oncode Institute

What are the most cited papers from Oncode Institute?

The most cited paper from Oncode Institute is "Signatures of mutational processes in human cancer" (Australian Pancreatic Cancer Genome Initiative et al., 2013), with 10,284 citations. Next come "Gene expression profiling predicts clinical outcome of breast cancer" (9,661) and "Mutational landscape determines sensitivity to PD-1 blockade in non–small cell lung cancer" (8,049).

Showing 50 of 60 papers. Every paper with more than 1,229 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Signatures of mutational processes in human cancer Australian Pancreatic Cancer Genome Initiative et al. · Nature Open access 14 Aug 2013 10,284
2 Gene expression profiling predicts clinical outcome of breast cancer Laura van ‘t Veer, Hongyue A. Dai, Marc J. van de Vijver et al. · Nature Open access 2002 9,661
3 Mutational landscape determines sensitivity to PD-1 blockade in non–small cell lung cancer Naiyer A. Rizvi et al. · Science Open access 12 Mar 2015 8,049
4 Computational Radiomics System to Decode the Radiographic Phenotype Joost J. M. van Griethuysen, Andriy Fedorov, Chintan Parmar et al. · Cancer Research Open access 31 Oct 2017 6,776
5 A Gene-Expression Signature as a Predictor of Survival in Breast Cancer Marc J. van de Vijver et al. · New England Journal of Medicine Open access 18 Dec 2002 6,562
6 A System for Stable Expression of Short Interfering RNAs in Mammalian Cells Thijn R. Brummelkamp, René Bernards, Reuven Agami · Science Open access 19 Apr 2002 4,319
7 The evolving tumor microenvironment: From cancer initiation to metastatic outgrowth Karin E. de Visser, Johanna A. Joyce · Cancer Cell Open access Mar 2023 4,002
8 The repertoire of mutational signatures in human cancer Ludmil B. Alexandrov et al. · Nature Open access1,384 authors 5 Feb 2020 3,854
9 Pan-cancer analysis of whole genomes Lauri A. Aaltonen et al. · Nature Open access1,324 authors 5 Feb 2020 3,360
10 Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma Jesse Meir Zaretsky et al. · New England Journal of Medicine Open access 13 Jul 2016 3,284
11 Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers Karoline B. Kuchenbaecker et al. · JAMA Open access 20 Jun 2017 2,963
12 B cells and tertiary lymphoid structures promote immunotherapy response Beth Ann Helmink et al. · Nature Open access 15 Jan 2020 2,809
13 Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1 Daniel J. Klionsky et al. · Autophagy Open access2,930 authors 2 Jan 2021 2,743
14 The human tumor microbiome is composed of tumor type–specific intracellular bacteria Deborah Nejman et al. · Science Open access 28 May 2020 2,523
15 The Human Cell Atlas Aviv Regev et al. · eLife Open access 5 Dec 2017 2,441
16 International network of cancer genome projects Jennifer L. Jennings et al. · Nature Open access256 authors 13 Apr 2010 2,439
17 Landscape of somatic mutations in 560 breast cancer whole-genome sequences Serena Nik‐Zainal et al. · Nature Open access 29 Apr 2016 2,395
18 Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression Urmo Võsa et al. · Nature Genetics Open access114 authors Sep 2021 2,339
19 A Landscape of Pharmacogenomic Interactions in Cancer Francesco Iorio et al. · Cell Open access Jul 2016 2,333
20 Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs Alfred H. Schinkel, Jasper Smit, Olaf van Tellingen et al. · Cell May 1994 2,298
21 Regulation and Function of the PD-L1 Checkpoint Chong Sun, Riccardo Mezzadra, Ton N. Schumacher · Immunity Open access Mar 2018 2,294
22 Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes Australian Pancreatic Cancer Genome Initiative et al. · Nature Open access127 authors 24 Oct 2012 2,133
23 Towards a systems understanding of MHC class I and MHC class II antigen presentation Jacques Neefjes, Marlieke L.M. Jongsma, Petra Paul et al. · Nature reviews. Immunology Review 11 Nov 2011 2,069
24 A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity Norman Sachs et al. · Cell Open access 7 Dec 2017 2,061
25 The essence of senescence: Figure 1. Thomas Kuilman, Chrysiis Michaloglou, Wolter J. Mooi et al. · Genes & Development Open access 15 Nov 2010 2,051
26 The β-Catenin/TCF-4 Complex Imposes a Crypt Progenitor Phenotype on Colorectal Cancer Cells Marc van de Wetering, Elena Lanchares Sancho, Cornelis L. Verweij et al. · Cell Open access Oct 2002 2,026
27 Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens Matthew M. Gubin et al. · Nature Open access 25 Nov 2014 2,015
28 Neutrophils in cancer: neutral no more Seth B. Coffelt, Max D. Wellenstein, Karin E. de Visser · Nature reviews. Cancer Review 10 Jun 2016 1,895
29 A Genomic and Functional Inventory of Deubiquitinating Enzymes Sebastian M. B. Nijman, Mark P.A. Luna‐Vargas, Arno Velds et al. · Cell Open access Dec 2005 1,866
30 Organoids in cancer research Jarno Drost, Hans C. Clevers · Nature reviews. Cancer ReviewOpen access 24 Apr 2018 1,820
31 Patient-Derived Xenograft Models: An Emerging Platform for Translational Cancer Research Manuel M. Hidalgo, Frédéric Amant, Andrew Victor Biankin et al. · Cancer Discovery Open access 16 Jul 2014 1,810
32 A Family of Drug Transporters: the Multidrug Resistance-Associated Proteins Piet Borst, Raymond Evers, Marcel Kool et al. · JNCI Journal of the National Cancer Institute 16 Aug 2000 1,766
33 IL-17-producing γδ T cells and neutrophils conspire to promote breast cancer metastasis Seth B. Coffelt, Kelly Kersten, Chris W. Doornebal et al. · Nature Open access 30 Mar 2015 1,746
34 Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy Eric A. Reits, James W. Hodge, Carla A. Herberts et al. · The Journal of Experimental Medicine Open access 24 Apr 2006 1,744
35 Short-course radiotherapy followed by chemotherapy before total mesorectal excision (TME) versus preoperative chemoradiotherapy, TME, and optional adjuvant chemotherapy in locally advanced rectal cancer (RAPIDO): a randomised, open-label, phase 3 trial Renu R. Bahadoer et al. · The Lancet Oncology Open access147 authors 7 Dec 2020 1,715
36 Epidemiology of Renal Cell Carcinoma Umberto Capitanio, Karim Bensalah, Axel Bex et al. · European Urology Open access 20 Sep 2018 1,699
37 SARS-CoV-2 productively infects human gut enterocytes Mart Matthias Lamers et al. · Science Open access May 2020 1,688
38 Defining ‘T cell exhaustion’ Christian U. Blank, W. Nicholas Haining, Werner Held et al. · Nature reviews. Immunology ReviewOpen access 30 Sep 2019 1,669
39 Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7 Gerrit G. Langer, Serge X. Cohen, Victor S. Lamzin et al. · Nature Protocols Open access 19 Jun 2008 1,651
40 CD8+ T cell states in human cancer: insights from single-cell analysis Anne M. van der Leun, Daniela S. Thommen, Ton N. Schumacher · Nature reviews. Cancer Review 5 Feb 2020 1,602
41 Cancer Exosomes Perform Cell-Independent MicroRNA Biogenesis and Promote Tumorigenesis Sónia A. Melo, Hikaru Sugimoto, Joyce T. O’Connell et al. · Cancer Cell Open access 24 Oct 2014 1,590
42 Therapeutic cancer vaccines Mansi Saxena, Sjoerd H. van der Burg, Cornelis J.M. Melief et al. · Nature reviews. Cancer Review 27 Apr 2021 1,589
43 Mammalian ABC Transporters in Health and Disease Piet Borst, R. Oude Elferink · Annual Review of Biochemistry ReviewOpen access Jun 2002 1,585
44 The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus Jacqueline J.L. Jacobs, Karin Kieboom, Silvia Marino et al. · Nature 1999 1,583
45 Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress Geert J.P.L. Kops, Tobias B. Dansen, Paulien E. Polderman et al. · Nature Open access Sep 2002 1,579
46 Genome-wide cell-free DNA fragmentation in patients with cancer Stephen Cristiano et al. · Nature Open access 29 May 2019 1,561
47 Eleven grand challenges in single-cell data science David Lähnemann et al. · Genome biology Open access 7 Feb 2020 1,493
48 Homozygous disruption of the murine MDR2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease Jasper Smit, Alfred H. Schinkel, Ronald P.J. Oude Elferink et al. · Cell Nov 1993 1,478
49 Molecular Reconstruction of Sleeping Beauty, a Tc1-like Transposon from Fish, and Its Transposition in Human Cells Zoltán Ivics, Perry B. Hackett, Ronald H.A. Plasterk et al. · Cell Open access Nov 1997 1,446
50 Neoadjuvant immunotherapy leads to pathological responses in MMR-proficient and MMR-deficient early-stage colon cancers Myriam Chalabi et al. · Nature Medicine Open access Apr 2020 1,437

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.