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Institution · OncoGenex Pharmaceuticals (United States)

Most cited papers from OncoGenex Pharmaceuticals (United States)

OncoGenex Pharmaceuticals (United States)

What are the most cited papers from OncoGenex Pharmaceuticals (United States)?

The most cited paper from OncoGenex Pharmaceuticals (United States) is "T-cell antigen CD28 mediates adhesion with B cells by interacting with activation antigen B7/BB-1." (Peter S. Linsley, Edward A. Clark, Jeffrey A. Ledbetter, 1990), with 755 citations. Next come "Role of the CD28 receptor in T-cell activation" (681) and "Structure and Function of Human Amphiregulin: A Member of the Epidermal Growth Factor Family" (600).

Showing 50 of 59 papers. Every paper with more than 62 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 T-cell antigen CD28 mediates adhesion with B cells by interacting with activation antigen B7/BB-1. Peter S. Linsley, Edward A. Clark, Jeffrey A. Ledbetter · Proceedings of the National Academy of Sciences Open access Jul 1990 755
2 Role of the CD28 receptor in T-cell activation Carl H. June, Jeffrey A. Ledbetter, Peter S. Linsley et al. · Immunology Today 1990 681
3 Structure and Function of Human Amphiregulin: A Member of the Epidermal Growth Factor Family MOHAMMED SHOYAB, Gregory D. Plowman, Vicki L. McDonald et al. · Science 24 Feb 1989 600
4 Production of transforming growth factor beta 1 during repair of arterial injury. Mark W. Majesky, Volkhard Lindner, Daniel R. Twardzik et al. · Journal of Clinical Investigation Open access Sep 1991 533
5 T-Cell Proliferation Involving the CD28 Pathway Is Associated witH Cyclosporine-Resistant Interleukin 2 Gene Expression Carl H. June, Jeffrey A. Ledbetter, Marjorie Gillespie et al. · Molecular and Cellular Biology Open access Dec 1987 529
6 Inhibition of Endothelial Regeneration by Type-Beta Transforming Growth Factor from Platelets Ronald L. Heimark, Daniel R. Twardzik, Stephen Mark Schwartz · Science 5 Sep 1986 435
7 Cloning and sequence analysis of a cDNA for rat transforming growth factor-α David C. Lee, Timothy M. Rose, Nancy R. Webb et al. · Nature 7 Feb 1985 387
8 Amphiregulin: a bifunctional growth-modulating glycoprotein produced by the phorbol 12-myristate 13-acetate-treated human breast adenocarcinoma cell line MCF-7. MOHAMMED SHOYAB, V L McDonald, J G Bradley et al. · Proceedings of the National Academy of Sciences Open access Sep 1988 370
9 Molecular cloning and expression of an additional epidermal growth factor receptor-related gene. Gregory D. Plowman, Gena S. Whitney, M G Neubauer et al. · Proceedings of the National Academy of Sciences Open access Jul 1990 370
10 Epithelial Wound Healing Enhanced by Transforming Growth Factor-α and Vaccinia Growth Factor Gregory S. Schultz, Michael J. V. White, Robert O. Mitchell et al. · Science 16 Jan 1987 366
11 Integrins alpha v beta 3 and alpha v beta 5 contribute to cell attachment to vitronectin but differentially distribute on the cell surface. Elizabeth A. Wayner, Robert A. Orlando, David A. Cheresh · The Journal of Cell Biology Open access 15 May 1991 360
12 The Amphiregulin Gene Encodes a Novel Epidermal Growth Factor-Related Protein with Tumor-Inhibitory Activity Gregory D. Plowman, Janell M. Green, Vicki L. McDonald et al. · Molecular and Cellular Biology Open access May 1990 357
13 Condensation of the chromatin at the membrane of an apoptotic nucleus is not associated with activation of an endonuclease F Oberhammer, Gerhard Fritsch, Mascha C. Schmied et al. · Journal of Cell Science Feb 1993 277
14 Molecular events in the processing of recombinant type 1 pre-pro-transforming growth factor beta to the mature polypeptide. Larry E. Gentry, Mario N. Lioubin, A F Purchio et al. · Molecular and Cellular Biology Open access Oct 1988 267
15 Vaccinia virus encodes a polypeptide homologous to epidermal growth factor and transforming growth factor JOSEPH PATRICK BROWN, Daniel R. Twardzik, Hans Marquardt et al. · Nature 7 Feb 1985 250
16 Highly tumor-reactive, internalizing, mouse monoclonal antibodies to Le(y)-related cell surface antigens. I Hellström, H. Jacques Garrigues, Ursula Garrigues et al. · PubMed Apr 1990 239
17 Anti-tumor effects of antibody-alkaline phosphatase conjugates in combination with etoposide phosphate. P D Senter, Mark G. Saulnier, George J. Schreiber et al. · Proceedings of the National Academy of Sciences Open access Jul 1988 236
18 Site-directed Mutagenesis of Cysteine Residues in the Pro Region of the Transforming Growth Factor β1 Precursor Amy M. Brunner, Hans Marquardt, Alison R. Malacko et al. · Journal of Biological Chemistry Open access Aug 1989 224
19 Type 1 Transforming Growth Factor Beta: Amplified Expression and Secretion of Mature and Precursor Polypeptides in Chinese Hamster Ovary Cells Larry E. Gentry, Nancy R. Webb, Guan Lim et al. · Molecular and Cellular Biology Open access Oct 1987 220
20 Transforming Growth Factor-β2: cDNA Cloning and Sequence Analysis Linda Madisen, Nancy R. Webb, Timothy M. Rose et al. · DNA 1988 198
21 Inhibition of HIV replication by pokeweed antiviral protein targeted to CD4+ cells by monoclonal antibodies Joyce M. Zarling, Patricia A. Moran, Omar K. Haffar et al. · Nature Sep 1990 197
22 Molecular cloning, sequence analysis, and functional expression of a novel growth regulator, oncostatin M. Najma Iqbal Malik, J C Kallestad, Nancy L. Gunderson et al. · Molecular and Cellular Biology Open access Jul 1989 195
23 Effect of immunization with a vaccinia-HIV env recombinant on HIV infection of chimpanzees Shiu‐Lok Hu, Patricia N. Fultz, Harold M. McClure et al. · Nature 20 Aug 1987 194
24 Expression of AIDS virus envelope gene in recombinant vaccinia viruses Shiu-Lok Hu, Steve G. Kosowski, Joel M. Dalrymple · Nature 10 Apr 1986 188
25 Epithelins 1 and 2: isolation and characterization of two cysteine-rich growth-modulating proteins. MOHAMMED SHOYAB, V L McDonald, C A Byles et al. · Proceedings of the National Academy of Sciences Open access Oct 1990 182
26 Signal transduction through cd4 receptors: stimulatory vs. inhibitory activity is regulated by cd4 proximity to the cd31t cell receptor Jeffrey A. Ledbetter, Carl H. June, Peter S. Rabinovitch et al. · European Journal of Immunology Apr 1988 167
27 Effects of anti-gp120 monoclonal antibodies on CD4 receptor binding by the env protein of human immunodeficiency virus type 1 Peter S. Linsley, J A Ledbetter, Elaine Kinney-Thomas et al. · Journal of Virology Open access Oct 1988 156
28 Stimulation of Bone Resorption in Vitro by Synthetic Transforming Growth Factor-Alpha K J Ibbotson, Daniel R. Twardzik, S M D'Souza et al. · Science 24 May 1985 151
29 Developmental Expression of Rat Transforming Growth Factor-α mRNA David C. Lee, Rosemary A. Rochford, George J. Todaro et al. · Molecular and Cellular Biology Open access Dec 1985 147
30 Isolation and characterization of a putative endogenous benzodiazepineoid (endozepine) from bovine and human brain. MOHAMMED SHOYAB, Larry E. Gentry, Hans Marquardt et al. · Journal of Biological Chemistry Open access Sep 1986 139
31 Epidermal growth factor receptor occupancy inhibits vaccinia virus infection Deborah A. Eppstein, Y. Vivienne Marsh, Alain B. Schreiber et al. · Nature 19 Dec 1985 136
32 Complete amino acid sequence of human transforming growth factor type beta 2. Hans Marquardt, Mario N. Lioubin, Tatsuhiko N. Ikeda · Journal of Biological Chemistry Open access Sep 1987 136
33 Tyrosine phosphorylation of a 120-kilodalton pp60src substrate upon epidermal growth factor and platelet-derived growth factor receptor stimulation and in polyomavirus middle-T-antigen-transformed cells. S B Kanner, A B Reynolds, J. Thomas Parsons · Molecular and Cellular Biology Open access Feb 1991 132
34 HIV-infected humans, but not chimpanzees, have circulating cytotoxic T lymphocytes that lyse uninfected CD4+ cells. J M Zarling, J A Ledbetter, J Sias et al. · The Journal of Immunology Apr 1990 131
35 Interactions of recombinant and platelet transforming growth factor-β1 precursor with the insulin-like growth factor II/mannose 6-phosphate receptor Kristina S. Kovacina, George Steele-Perkins, A F Purchio et al. · Biochemical and Biophysical Research Communications Open access Apr 1989 126
36 Regulation of Cell Growth by Recombinant Oncostatin M Diane Horn, William C. Fitzpatrick, Peter T. Gompper et al. · Growth Factors 1990 115
37 Complete amino acid sequences of bovine and human endozepines. Homology with rat diazepam binding inhibitor. Hans Marquardt, George J. Todaro, MOHAMMED SHOYAB · Journal of Biological Chemistry Open access Jul 1986 114
38 Activation of prodrugs by antibody‐enzyme conjugates: a new approach to cancer therapy Peter D. Senter · The FASEB Journal Feb 1990 110
39 A phase I dose-escalation study of apatorsen (OGX-427), an antisense inhibitor targeting heat shock protein 27 (Hsp27), in patients with castration-resistant prostate cancer and other advanced cancers K.N. Chi, Evan Y. Yu, Cindy A. Jacobs et al. · Annals of Oncology Open access 29 Mar 2016 107
40 Synthesis of biologically active rat transforming growth factor I James P. Tam, Hans Marquardt, Daniel F. Rosberger et al. · Nature May 1984 103
41 Expression and characterization of transforming growth factor alpha precursor protein in transfected mammalian cells. Larry E. Gentry, Daniel R. Twardzik, Guan Lim et al. · Molecular and Cellular Biology Open access May 1987 99
42 Enhancement of the in vitro and in vivo antitumor activities of phosphorylated mitomycin C and etoposide derivatives by monoclonal antibody-alkaline phosphatase conjugates. P D Senter, George J. Schreiber, David L. Hirschberg et al. · PubMed Nov 1989 96
43 Custirsen (OGX-011) combined with cabazitaxel and prednisone versus cabazitaxel and prednisone alone in patients with metastatic castration-resistant prostate cancer previously treated with docetaxel (AFFINITY): a randomised, open-label, international, phase 3 trial Tomasz M. Beer, Sebastién J. Hotte, Fred Saad et al. · The Lancet Oncology 12 Oct 2017 92
44 T-cell responses to human AIDS virus in macaques immunized with recombinant vaccinia viruses Joyce M. Zarling, William R. Morton, Patricia A. Moran et al. · Nature 25 Sep 1986 92
45 Molecular Cloning of a Novel Bone-Forming Compound: Osteoinductive Factor Linda Madisen, MIKE NEUBAUER, Gregory D. Plowman et al. · DNA and Cell Biology Jun 1990 92
46 Custirsen in combination with docetaxel and prednisone for patients with metastatic castration-resistant prostate cancer (SYNERGY trial): a phase 3, multicentre, open-label, randomised trial Kim N. Chi, Celestia S. Higano, Brent A. Blumenstein et al. · The Lancet Oncology 7 Mar 2017 88
47 A synthetic fragment of rat transforming growth factor α with receptor binding and antigenic properties JOHN J. JUN. NESTOR, Sherry R. Newman, Barbara DeLustro et al. · Biochemical and Biophysical Research Communications May 1985 87
48 Transforming Growth Factor-β 1 Inhibits Ovarian Androgen Production: Gene Expression, Cellular Localization, Mechanisms(s), and Site(s) of Action* Eleuterio R. Hernández, Arye Hurwitz, Donna W. Payne et al. · Endocrinology Dec 1990 80
49 Reduced proliferation in T lymphocytes in aged humans is predominantly in the CD8+ subset, and is unrelated to defects in transmembrane signaling which are predominantly in the CD4+ subset Angelika Grossmann, Jeffrey A. Ledbetter, Peter S. Rabinovitch · Experimental Cell Research Feb 1989 74
50 Oncogenes and Growth Factors George J. Todaro Book chapter 1988 73

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.