| 1 |
Mutation detection and single-molecule counting using isothermal rolling-circle amplification
Paul M. Lizardi, Xiaohua C. Huang, Zhengrong Zhu et al. · Nature Genetics
|
Jul 1998 |
1,457 |
| 2 |
A closed tube format for amplification and detection of DNA based on energy transfer
Irina A. Nazarenko, S. K. Bhatnagar, Robert J. Hohman · Nucleic Acids Research
Open access |
Jun 1997 |
353 |
| 3 |
Big data analytics in smart grids: state‐of‐the‐art, challenges, opportunities, and future directions
Bishnu Prasad Bhattarai, Sumit Paudyal, Yusheng Luo et al. · IET Smart Grid
Open access |
5 Feb 2019 |
294 |
| 4 |
Histone H3 phosphorylation and expression of cyclins A and B1 measured in individual cells during their progression through G2 and mitosis
Gloria Juan, Frank Traganos, William M. James et al. · Cytometry
|
Jun 1998 |
263 |
| 5 |
Amplification and overexpression of HER-2/neu in carcinomas of the salivary gland: correlation with poor prognosis.
Michael F. Press, Malcolm C. Pike, Gene Hung et al. · PubMed
|
Nov 1994 |
222 |
| 6 |
Heavy-duty truck electrification and the impacts of depot charging on electricity distribution systems
Brennan Borlaug, Matteo Muratori, Madeline Gilleran et al. · Nature Energy
|
21 Jun 2021 |
212 |
| 7 |
G Protein-Mediated Neuronal DNA Fragmentation Induced by Familial Alzheimer's Disease-Associated Mutants of APP
Tomoki Yamatsuji, Takashi Matsui, Takashi Okamoto et al. · Science
|
31 May 1996 |
211 |
| 8 |
Reviewing the impacts of distributed generation on distribution system protection
M.T. Doyle
Conference paper |
25 Jun 2003 |
181 |
| 9 |
Prognostic significance of HER-2/neu gene amplification status by fluorescence in Situ hybridization of prostate carcinoma
Jeffrey S. Ross, Christine E. Sheehan, Alida Hayner‐Buchan et al. · Cancer
Open access |
Jun 1997 |
140 |
| 10 |
Phosphorylation-induced Rearrangement of the Histone H3 NH2-terminal Domain during Mitotic Chromosome Condensation
Debra M. Sauvé, Hilary J. Anderson, Jill Ray et al. · The Journal of Cell Biology
Open access |
19 Apr 1999 |
139 |
| 11 |
Amplification of padlock probes for DNA diagnostics by cascade rolling circle amplification or the polymerase chain reaction.
David Thomas, Gerardo Nardone, Sandra K. Randall · PubMed
|
Dec 1999 |
111 |
| 12 |
Effects of mammographic density and benign breast disease on breast cancer risk (United States)
Celia Byrne, Catherine Schairer, Louise Annette Brinton et al. · Cancer Causes & Control
|
Feb 2001 |
107 |
| 13 |
HER-2/neu gene amplification status in prostate cancer by fluorescence in situ hybridization
Jeffrey S. Ross, Christine Sheehan, Alida Hayner‐Buchan et al. · Human Pathology
|
Jul 1997 |
105 |
| 14 |
Recombination Induced by Triple-Helix-Targeted DNA Damage in Mammalian Cells
A. Fawad Faruqi, Michael M. Seidman, David Jay Segal et al. · Molecular and Cellular Biology
Open access |
Dec 1996 |
102 |
| 15 |
Common clonal origin of synchronous primary head and neck squamous cell carcinomas: Analysis by tumor karyotypes and fluorescence in situ hybridization
Maria J. Worsham, Sandra R. Wolman, Thomas E. Carey et al. · Human Pathology
|
Mar 1995 |
100 |
| 16 |
Blocking extracellular activation of myostatin as a strategy for treating muscle wasting
Michelle Pirruccello, Justin Jackson, Stefan Wawersik et al. · Scientific Reports
Open access |
29 Jan 2018 |
94 |
| 17 |
Physical mapping of the holoprosencephaly critical region on chromosome 7q36
Fiorella Gurrieri, Barbara J. Trask, Ger van den Engh et al. · Nature Genetics
|
Mar 1993 |
93 |
| 18 |
Identification of a DinB/UmuC homolog in the archeon Sulfolobus solfataricus
Olga I. Kulaeva, Eugene V. Koonin, John P. McDonald et al. · Mutation research. Fundamental and molecular mechanisms of mutagenesis
|
Oct 1996 |
91 |
| 19 |
A brief account of viral vectors and their promise for gene therapy
M H Finer, Joseph C. Glorioso · Gene Therapy
Open access |
2017 |
77 |
| 20 |
A Special Fluorescent In Situ Hybridization Technique to Study Peripheral Blood and Assess the Effectiveness of Interferon Therapy in Chronic Myeloid Leukemia
Ismael Buño, William A. Wyatt, Alan R. Zinsmeister et al. · Blood
|
Oct 1998 |
75 |
| 21 |
HER-2/neuOncogene Amplification by Fluorescence In Situ Hybridization in Epithelial Tumors of the Ovary
Jeffrey S. Ross, Fan Yang, Bhaskar Kallakury et al. · American Journal of Clinical Pathology
|
Mar 1999 |
74 |
| 22 |
Mutagenesis by third-strand-directed psoralen adducts in repair-deficient human cells: high frequency and altered spectrum in a xeroderma pigmentosum variant.
Manidipa Raha, G Wang, Michael M. Seidman et al. · Proceedings of the National Academy of Sciences
Open access |
2 Apr 1996 |
71 |
| 23 |
ONCR-177, an Oncolytic HSV-1 Designed to Potently Activate Systemic Antitumor Immunity
Brian B. Haines, Agnieszka Denslow, Peter Grzesik et al. · Cancer Immunology Research
|
22 Dec 2020 |
70 |
| 24 |
Effectiveness of managed gene flow in reducing genetic divergence associated with captive breeding
Charles D. Waters, Jeffrey J. Hard, Marine Servane Ono Brieuc et al. · Evolutionary Applications
Open access |
18 Sep 2015 |
62 |
| 25 |
Glioblastoma-instructed astrocytes suppress tumour-specific T cell immunity
Camilo Faust Akl et al. · Nature
Open access |
21 May 2025 |
61 |
| 26 |
Tumor-Specific Fluorescence Antibody Imaging Enables Accurate Staging Laparoscopy in an Orthotopic Model of Pancreatic Cancer
Hop S. Tran Cao, Sharmeela Kaushal, Cristina Angela Metildi et al. · Hepatogastroenterology
Open access |
22 Dec 2011 |
60 |
| 27 |
Differences in the kinetic properties of BamHI endonuclease and methylase with linear DNA substrates.
Gerardo Nardone, Jacinta Teresa George, Jack G. Chirikjian · Journal of Biological Chemistry
Open access |
Sep 1986 |
60 |
| 28 |
Identification of HER-2/neu oncogene amplification by fluorescence in situ hybridization in stage I endometrial carcinoma.
Michael W. Riben, John H. Malfetano, Tipu Nazeer et al. · PubMed
|
Aug 1997 |
53 |
| 29 |
Evaluation of school children at high risk for fragile X syndrome utilizing buccal cell FMR‐1 testing
Randi Jenssen Hagerman, Philip Wilson, Louise W. Staley et al. · American Journal of Medical Genetics
|
15 Jul 1994 |
49 |
| 30 |
Rescue of the limb deformity in Hammertoe mutant mice by retinoic acid-induced cell death
Harleen Singh Ahuja, William G. James, Zahra Zakeri · Developmental Dynamics
|
Apr 1997 |
47 |
| 31 |
Molecular genetic analysis of the 3p — syndrome
Maude Elvira Phipps, Farida Latif, Amanda H. Prowse et al. · Human Molecular Genetics
Open access |
1994 |
45 |
| 32 |
Development of intravenously administered synthetic RNA virus immunotherapy for the treatment of cancer
Edward M. Kennedy et al. · Nature Communications
Open access |
7 Oct 2022 |
43 |
| 33 |
Massively Digitized Power Grid: Opportunities and Challenges of Use-Inspired AI
Le Xie, Xiangtian Zheng, Yannan Sun et al. · Proceedings of the IEEE
Open access |
22 Jun 2022 |
43 |
| 34 |
Seismic inversion and uncertainty quantification using transdimensional Markov chain Monte Carlo method
Dehan Zhu, Richard L. Gibson · Geophysics
|
6 Apr 2018 |
41 |
| 35 |
Fluorescence in situ hybridization: A new tool for the pathologist
Sandra R. Wolman · Human Pathology
|
Jun 1994 |
41 |
| 36 |
Fluorescence in situ hybridization (fish): A user's guide to optimal preparation of cytologic specimens
Andrea D. Abati, Jeffrey S. Sanford, Patricia A. Fetsch et al. · Diagnostic Cytopathology
|
Dec 1995 |
41 |
| 37 |
p53 compound heterozygosity in a severely affected child with Li-Fraumeni Syndrome
Susan Quesnel, Sigitas Jonas Verselis, Carol Portwine et al. · Oncogene
|
8 Jul 1999 |
39 |
| 38 |
Genetic variability and differentiation in red deer (Cervus elaphus L) of Central Europe
GB Hartl, R. Willing, Glenn Lang et al. · Genetics Selection Evolution
Open access |
15 Oct 1990 |
36 |
| 39 |
Maintaining a wild phenotype in a conservation hatchery program for Chinook salmon: The effect of managed breeding on early male maturation
Donald A. Larsen, Deborah L. Harstad, Abby E. Fuhrman et al. · PLoS ONE
Open access |
15 May 2019 |
34 |
| 40 |
Genomewide association analyses of fitness traits in captive‐reared Chinook salmon: Applications in evaluating conservation strategies
Charles D. Waters, Jeffrey J. Hard, Marine Servane Ono Brieuc et al. · Evolutionary Applications
Open access |
22 Jan 2018 |
34 |
| 41 |
PMU based generator parameter identification to improve the system planning and operation
Chin-Chu Tsai, Wei‐Jen Lee, Eithar Nashawati et al.
Conference paper |
Jul 2012 |
34 |
| 42 |
Genetic counseling in a navajo hereditary nonpolyposis colorectal cancer kindred
Henry T. Lynch, T. Drouhard, Hans F. A. Vasen et al. · Cancer
Open access |
1996 |
34 |
| 43 |
Arming oHSV with ULBP3 drives abscopal immunity in lymphocyte-depleted glioblastoma
Hans‐Georg Wirsching et al. · JCI Insight
Open access |
10 Jul 2019 |
33 |
| 44 |
Breast cancer information on the web
Stephen Henry Friend, Anne‐Lise Børresen, Larry Brody et al. · Nature Genetics
|
Nov 1995 |
33 |
| 45 |
Photoimmunotherapy Inhibits Tumor Recurrence After Surgical Resection on a Pancreatic Cancer Patient-Derived Orthotopic Xenograft (PDOX) Nude Mouse Model
Yukihiko Hiroshima, Ali A. Maawy, Yong Zhang et al. · Annals of Surgical Oncology
Open access |
16 Apr 2015 |
33 |
| 46 |
Breeding success of four male life history types of spring Chinook Salmon spawning in an artificial stream
Steve L. Schroder, Curtis M. Knudsen, Todd N. Pearsons et al. · Environmental Biology of Fishes
Open access |
12 Apr 2011 |
29 |
| 47 |
CANCER BIOLOGY: Drug-resistant breast cancer cells frequently retain expression of a functional wild-type p53 protein
Jean M. Gudas, Hoang Duc Nguyen, Tao Li et al. · Carcinogenesis
|
1996 |
28 |
| 48 |
Application of Biotin, Digoxigenin or Fluorescein Conjugated Deoxynucleotides to Label DNA Strand Breaks for Analysis of Cell Proliferation and Apoptosis Using Flow Cytometry
Xun Li, William M. James, Frank Traganos et al. · Biotechnic & Histochemistry
|
1995 |
27 |
| 49 |
Design of an Interferon-Resistant Oncolytic HSV-1 Incorporating Redundant Safety Modalities for Improved Tolerability
Edward M. Kennedy, Terry Farkaly, Peter Grzesik et al. · Molecular Therapy — Oncolytics
Open access |
8 Aug 2020 |
26 |
| 50 |
Pancreatic Cancer: A Time to Change
Cristina Rosa Ferrone, David P. Ryan · Annals of Surgery
|
12 May 2020 |
26 |