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Most cited papers from OncoTherapy Science (Japan)

What are the most cited papers from OncoTherapy Science (Japan)?

The most cited paper from OncoTherapy Science (Japan) is "Functional analysis of Arabidopsis NCED6 and NCED9 genes indicates that ABA synthesized in the endosperm is involved in the induction of seed dormancy" (Valérie Lefebvre, Helen North, Anne Frey et al., 2006), with 504 citations. Next come "Phase II Clinical Trial of Multiple Peptide Vaccination for Advanced Head and Neck Cancer Patients Revealed Induction of Immune Responses and Improved OS" (156) and "Development of an orally-administrative MELK-targeting inhibitor that suppresses the growth of various types of human cancer" (155).

Showing 50 of 60 papers. Every paper with more than 13 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Functional analysis of Arabidopsis NCED6 and NCED9 genes indicates that ABA synthesized in the endosperm is involved in the induction of seed dormancy Valérie Lefebvre, Helen North, Anne Frey et al. · The Plant Journal 10 Jan 2006 504
2 Phase II Clinical Trial of Multiple Peptide Vaccination for Advanced Head and Neck Cancer Patients Revealed Induction of Immune Responses and Improved OS Yoshihiro Yoshitake, Daiki Fukuma, Akira Yuno et al. · Clinical Cancer Research 13 Nov 2014 156
3 Development of an orally-administrative MELK-targeting inhibitor that suppresses the growth of various types of human cancer Suyoun Chung, Hanae Suzuki, Takashi Miyamoto et al. · Oncotarget Open access 21 Dec 2012 155
4 Profiling of Hormones and Related Metabolites in Seed Dormancy and Germination Studies Mitsunori Seo, Yusuke Jikumaru, Yuji Kamiya · Methods in molecular biology Book chapter 2011 150
5 TOPK inhibitor induces complete tumor regression in xenograft models of human cancer through inhibition of cytokinesis Yo Matsuo, Jae‐Hyun Park, Takashi Miyamoto et al. · Science Translational Medicine 22 Oct 2014 140
6 Phase I clinical trial using peptide vaccine for human vascular endothelial growth factor receptor 2 in combination with gemcitabine for patients with advanced pancreatic cancer Motoki Miyazawa, R. Ohsawa, Takuya Tsunoda et al. · Cancer Science Open access 27 Oct 2009 117
7 Identification of a Novel Tumor-Associated Antigen, Cadherin 3/P-Cadherin, as a Possible Target for Immunotherapy of Pancreatic, Gastric, and Colorectal Cancers Katsunori Imai, Shinya Hirata, Atsushi Irie et al. · Clinical Cancer Research Open access 15 Oct 2008 112
8 Phase I clinical study of multiple epitope peptide vaccine combined with chemoradiation therapy in esophageal cancer patients Hisae Iinuma, Ryoji Fukushima, Tsuyoshi Inaba et al. · Journal of Translational Medicine Open access 2014 95
9 HLA‐A2‐restricted CTL epitopes of a novel lung cancer‐associated cancer testis antigen, cell division cycle associated 1, can induce tumor‐reactive CTL Michiko Harao, Shinya Hirata, Atsushi Irie et al. · International Journal of Cancer 3 Sep 2008 92
10 T-LAK Cell-Originated Protein Kinase (TOPK) as a Prognostic Factor and a Potential Therapeutic Target in Ovarian Cancer Yuji Ikeda, Jae‐Hyun Park, Takashi Miyamoto et al. · Clinical Cancer Research 23 Jun 2016 88
11 Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia Houda Alachkar, Martin Mutonga, Klaus Hans Metzeler et al. · Oncotarget Open access 28 Oct 2014 67
12 A first-in-human study investigating biodistribution, safety and recommended dose of a new radiolabeled MAb targeting FZD10 in metastatic synovial sarcoma patients Anne‐Laure Giraudet et al. · BMC Cancer Open access 8 Jun 2018 65
13 Effective screening of T cells recognizing neoantigens and construction of T-cell receptor-engineered T cells Taigo Kato, Tatsuo Matsuda, Yuji Ikeda et al. · Oncotarget Open access 13 Jan 2018 62
14 Homoepitaxial Hydride Vapor Phase Epitaxy Growth on GaN Wafers Manufactured by the Na-Flux Method Masayuki Imanishi, Takehiro Yoshida, Toshio Kitamura et al. · Crystal Growth & Design 5 Jun 2017 60
15 Effective growth-suppressive activity of maternal embryonic leucine-zipper kinase (MELK) inhibitor against small cell lung cancer Hiroyuki Inoue, Taigo Kato, Sope Omowale Olugbile et al. · Oncotarget Open access 10 Feb 2016 57
16 Oncogenic roles of TOPK and MELK, and effective growth suppression by small molecular inhibitors in kidney cancer cells Taigo Kato, Hiroyuki Inoue, Seiya Imoto et al. · Oncotarget Open access 26 Feb 2016 55
17 WHSC1L1-mediated EGFR mono-methylation enhances the cytoplasmic and nuclear oncogenic activity of EGFR in head and neck cancer Vassiliki Saloura, Theodore Vougiouklakis, Makda Getachew Zewde et al. · Scientific Reports Open access 19 Jan 2017 54
18 A VEGF receptor vaccine demonstrates preliminary efficacy in neurofibromatosis type 2 Ryota Tamura, Masato Fujioka, Yukina Morimoto et al. · Nature Communications Open access 17 Dec 2019 53
19 Method for comparing the structures of protein ligand‐binding sites and application for predicting protein–drug interactions Ryoichi Minai, Yo Matsuo, Hiroyuki Onuki et al. · Proteins Structure Function and Bioinformatics 23 Jan 2008 53
20 SMYD3-mediated lysine methylation in the PH domain is critical for activation of AKT1 Yuichiro Yoshioka, Takehiro Suzuki, Yo Matsuo et al. · Oncotarget Open access 8 Sep 2016 52
21 A phase IB trial of 24-hour intravenous PX-12, a thioredoxin-1 inhibitor, in patients with advanced gastrointestinal cancers Amanda F. Baker, K. N. Adab, Natarajan Raghunand et al. · Investigational New Drugs Open access 18 Jun 2012 52
22 p53-independent p21 induction by MELK inhibition Tatsuo Matsuda, Taigo Kato, Kazuma Kiyotani et al. · Oncotarget Open access 15 Jun 2017 51
23 A novel tumor‐associated antigen, cell division cycle 45‐like can induce cytotoxic T‐lymphocytes reactive to tumor cells Yusuke Tomita, Katsunori Imai, Satoru Senju et al. · Cancer Science Open access 13 Jan 2011 46
24 Critical roles of SMYD2-mediated β-catenin methylation for nuclear translocation and activation of Wnt signaling Xiaolan Deng, Ryuji Hamamoto, Theodore Vougiouklakis et al. · Oncotarget Open access 27 Jul 2017 45
25 α‐particle therapy for synovial sarcoma in the mouse using an astatine‐211‐labeled antibody against frizzled homolog 10 Huizi Keiko Li, Aya Sugyo, Atsushi B. Tsuji et al. · Cancer Science Open access 27 Jun 2018 41
26 Preclinical evaluation of biomarkers associated with antitumor activity of MELK inhibitor Suyoun Chung, Kyoko Kijima, Aiko Kudo et al. · Oncotarget Open access 24 Feb 2016 40
27 TOPK (T‐ LAK cell‐originated protein kinase) inhibitor exhibits growth suppressive effect on small cell lung cancer Jae‐Hyun Park, Hiroyuki Inoue, Taigo Kato et al. · Cancer Science Open access 11 Jan 2017 39
28 Protein lysine methyltransferase SMYD 3 is involved in tumorigenesis through regulation of HER 2 homodimerization Yuichiro Yoshioka, Takehiro Suzuki, Yo Matsuo et al. · Cancer Medicine Open access 22 Jun 2017 35
29 FZD10‐targeted α‐radioimmunotherapy with 225Ac‐labeled OTSA101 achieves complete remission in a synovial sarcoma model Hitomi Sudo, Atsushi B. Tsuji, Aya Sugyo et al. · Cancer Science Open access 21 Dec 2021 31
30 Characterization of the B-cell receptor repertoires in peanut allergic subjects undergoing oral immunotherapy Kazuma Kiyotani, Tu H Mai, Rui Yamaguchi et al. · Journal of Human Genetics Open access 30 Nov 2017 30
31 Identification of superoxide production by Arabidopsis thaliana aldehyde oxidases AAO1 and AAO3 Maryam Zarepour, Kristina Simon, Moritz Wilch et al. · Plant Molecular Biology 14 Oct 2012 30
32 Development of novel SUV39H2 inhibitors that exhibit growth suppressive effects in mouse xenograft models and regulate the phosphorylation of H2AX Theodore Vougiouklakis, Vassiliki Saloura, Jae‐Hyun Park et al. · Oncotarget Open access 7 Aug 2018 29
33 Clinical and histopathological analyses of VEGF receptors peptide vaccine in patients with primary glioblastoma - a case series Ryota Tamura, Yukina Morimoto, Kenzo Kosugi et al. · BMC Cancer Open access 12 Mar 2020 28
34 KNN lead-free piezoelectric films grown by sputtering Kenji Shibata, Kazutoshi Watanabe, Toshiaki Kuroda et al. · Applied Physics Letters 29 Aug 2022 25
35 Stromal Matrix Protein Expression Following Preoperative Systemic Therapy in Breast Cancer Anna‐Mária Tõkés, Attila Marcell Szász, Andrea Farkas et al. · Clinical Cancer Research Open access 15 Jan 2009 25
36 A Comprehensive System for Generation and Evaluation of Induced Pluripotent Stem Cells Using piggyBac Transposition Tomoyuki Tsukiyama, Megumi Kato‐Itoh, Hiromitsu Nakauchi et al. · PLoS ONE Open access 25 Mar 2014 25
37 Identification of HLA-A24-Restricted Novel T Cell Epitope Peptides Derived from P-Cadherin and Kinesin Family Member 20A Ryuji Osawa, Takuya Tsunoda, Sachiko Yoshimura et al. · BioMed Research International Open access 2012 25
38 Development of GaN substrate with a large diameter and small orientation deviation Takehiro Yoshida, Masayuki Imanishi, Toshio Kitamura et al. · physica status solidi (b) 6 Feb 2017 24
39 T-LAK cell-originated protein kinase presents a novel therapeutic target inFLT3-ITD mutated acute myeloid leukemia Houda Alachkar, Martin Mutonga, Gregory Malnassy et al. · Oncotarget Open access 2 Oct 2015 24
40 Identification of CDCA1‐derived long peptides bearing both CD4+ and CD8+ T‐cell epitopes: CDCA1‐specific CD4+ T‐cell immunity in cancer patients Yusuke Tomita, Akira Yuno, Hirotake Tsukamoto et al. · International Journal of Cancer Open access 8 Jul 2013 24
41 In vivo therapeutic effect of CDH3/P-cadherin-targeting radioimmunotherapy Hiroki Yoshioka, Shinji Yamamoto, Hirofumi Hanaoka et al. · Cancer Immunology Immunotherapy Open access 5 Jan 2012 22
42 Effect of Engine Output on Maneuverability of a VLCC in Still Water and Adverse Weather Conditions Hironori Yasukawa, Mochammad Zaky, Isao Yonemasu et al. · Journal of Marine Science and Technology Open access 18 Mar 2017 21
43 Anti-myeloma activity of MELK inhibitor OTS167: effects on drug-resistant myeloma cells and putative myeloma stem cell replenishment of malignant plasma cells Andrew T. Stefka, J-H Park, Yo Matsuo et al. · Blood Cancer Journal Open access 19 Aug 2016 20
44 An oncofetal antigen, IMP-3-derived long peptides induce immune responses of both helper T cells and CTLs Masatoshi Hirayama, Yusuke Tomita, Akira Yuno et al. · OncoImmunology Open access 4 Jan 2016 20
45 Analysis of rate-based congestion control algorithms for ATM networks. 1. Steady state analysis Hiroyuki Ohsaki, Masayuki Murata, Hiroshi Suzuki et al. Conference paper 19 Nov 2002 20
46 FET family proto-oncogene Fus contributes to self-renewal of hematopoietic stem cells Takeaki Sugawara, Hideyuki Oguro, Masamitsu Negishi et al. · Experimental Hematology Open access 22 Apr 2010 19
47 Ergonomics of Various Modalities for Ear Surgery Matthew Ern Lin, Sheng Zhou, Seiji Kakeheta et al. · OTO Open Open access Jul 2024 18
48 Development of small molecular compounds targeting cancer stem cells Jae‐Hyun Park, Suyoun Chung, Yo Matsuo et al. · MedChemComm Open access 11 Nov 2016 18
49 Implementation of a Gate-Level Evolvable Hardware Chip Masaya Iwata, Isamu Kajitani, Yong Liu et al. · Lecture notes in computer science Conference paper 2001 18
50 Investigation on the rudder force of a ship in large drifting conditions with the MMG model Hironori Yasukawa, Tomohiro Ishikawa, Yasuo Yoshimura · Journal of Marine Science and Technology 30 Jan 2021 17

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.