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Most cited papers from Organix (United States)

What are the most cited papers from Organix (United States)?

The most cited paper from Organix (United States) is "Cannabidiol displays unexpectedly high potency as an antagonist of CB 1 and CB 2 receptor agonists in vitro" (Adèle Thomas, Gemma L. Baillie, Angela M. Phillips et al., 2007), with 761 citations. Next come "A biosynthetic pathway for anandamide" (474) and "Behavioral, biochemical, and molecular modeling evaluations of cannabinoid analogs" (413).

Showing 50 of 60 papers. Every paper with more than 44 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Cannabidiol displays unexpectedly high potency as an antagonist of CB 1 and CB 2 receptor agonists in vitro Adèle Thomas, Gemma L. Baillie, Angela M. Phillips et al. · British Journal of Pharmacology Open access 23 Jan 2007 761
2 A biosynthetic pathway for anandamide Jie Liu, Lei Wang, Judith Dale Harvey-White et al. · Proceedings of the National Academy of Sciences 28 Aug 2006 474
3 Behavioral, biochemical, and molecular modeling evaluations of cannabinoid analogs Billy R. Martin, David R. Compton, Brian F. Thomas et al. · Pharmacology Biochemistry and Behavior Nov 1991 413
4 1-(4-Methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one (Pyrovalerone) Analogues: A Promising Class of Monoamine Uptake Inhibitors Peter C. Meltzer, David Butler, Jeffrey R. Deschamps et al. · Journal of Medicinal Chemistry Open access 25 Jan 2006 412
5 Multiple pathways involved in the biosynthesis of anandamide Jie Liu, Lei Wang, Judith Dale Harvey-White et al. · Neuropharmacology Open access 7 Jun 2007 309
6 Selective Ligands and Cellular Effectors of a G Protein-Coupled Endothelial Cannabinoid Receptor László Offertáler, Fong-Ming Mo, Sándor Bátkai et al. · Molecular Pharmacology 27 Feb 2003 229
7 CB 1 cannabinoid receptor‐mediated modulation of food intake in mice Jenny L. Wiley, James J. Burston, Darnica C Leggett et al. · British Journal of Pharmacology Open access 21 Mar 2005 219
8 Discovery and characterization of endogenous cannabinoids Billy R. Martin, Raphael Mechoulam, R K Razdan · Life Sciences Jul 1999 204
9 Cannabinoid CB 2 Receptor Activation Decreases Cerebral Infarction in a Mouse Focal Ischemia/Reperfusion Model Ming Zhang, Billy R. Martin, Martin W. Adler et al. · Journal of Cerebral Blood Flow & Metabolism Open access 24 Jan 2007 166
10 Further Evidence of Dopamine Transporter Dysregulation in ADHD: A Controlled PET Imaging Study Using Altropane Thomas J. Spencer, Joseph Biederman, Bertha Kalifon Madras et al. · Biological Psychiatry Open access 25 May 2007 149
11 Substituted 3-phenyltropane analogs of cocaine: synthesis, inhibition of binding at cocaine recognition sites, and positron emission tomography imaging Peter C. Meltzer, A. Y. Liang, A.-L. Brownell et al. · Journal of Medicinal Chemistry Open access Apr 1993 138
12 The monoacylglycerol lipase inhibitor JZL184 suppresses inflammatory pain in the mouse carrageenan model Sudeshna Ghosh, Laura E. Wise, Yugang Chen et al. · Life Sciences Open access 28 Jun 2012 127
13 Development of the first potent and specific inhibitors of endocannabinoid biosynthesis Tiziana Bisogno, Maria Grazia Cascio, Bijali Saha et al. · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids Open access 24 Jan 2006 125
14 Highly Selective CB1 Cannabinoid Receptor Ligands and Novel CB1/VR1 Vanilloid Receptor “Hybrid” Ligands Vincenzo Di Marzo, Tiziana Bisogno, Luciano De Petrocellis et al. · Biochemical and Biophysical Research Communications Feb 2001 119
15 Modulation of the balance between cannabinoid CB1 and CB2 receptor activation during cerebral ischemic/reperfusion injury M. Zhang, Billy R. Martin, Martin W. Adler et al. · Neuroscience Open access 26 Jan 2008 117
16 Rapid detection of Parkinson's disease by SPECT with altropane: A selective ligand for dopamine transporters Alan J. Fischman, Ali A. Bonab, John W. Babich et al. · Synapse Jun 1998 116
17 Cardiovascular Effects of 2-Arachidonoyl Glycerol in Anesthetized Mice Zoltán Járai, Jens A. Wagner, Sravan Kumar Goparaju et al. · Hypertension Open access Feb 2000 102
18 Inhibition of monoacylglycerol lipase and fatty acid amide hydrolase by analogues of 2‐arachidonoylglycerol Nazdar Ghafouri, Gunnar Tiger, Raj K. Razdan et al. · British Journal of Pharmacology Open access Nov 2004 102
19 Modulation of Cannabinoid Receptor Activation as a Neuroprotective Strategy for EAE and Stroke Ming Zhang, Billy R. Martin, Martin W. Adler et al. · Journal of Neuroimmune Pharmacology Open access 2 Mar 2009 101
20 The psychoactive plant cannabinoid, Δ 9 ‐tetrahydrocannabinol, is antagonized by Δ 8 ‐ and Δ 9 ‐tetrahydrocannabivarin in mice in vivo Roger G. Pertwee, Adèle Thomas, Leslie A. Stevenson et al. · British Journal of Pharmacology Open access 23 Jan 2007 99
21 The Discovery of an Unusually Selective and Novel Cocaine Analog: Difluoropine. Synthesis and Inhibition of Binding at Cocaine Recognition Sites Peter C. Meltzer, A. Y. Liang, Bertha Kalifon Madras · Journal of Medicinal Chemistry Open access Jun 1994 95
22 The CB2 cannabinoid receptor-selective agonist O-3223 reduces pain and inflammation without apparent cannabinoid behavioral effects Steven G. Kinsey, Anu Mahadevan, Bingjun Zhao et al. · Neuropharmacology Open access 17 Sep 2010 94
23 Inhibition of Monoacylglycerol Lipase Attenuates Nonsteroidal Anti-Inflammatory Drug-Induced Gastric Hemorrhages in Mice Steven G. Kinsey, Daniel K. Nomura, Scott T. O’Neal et al. · Journal of Pharmacology and Experimental Therapeutics Open access 10 Jun 2011 91
24 Structure−Activity Analysis of Anandamide Analogs: Relationship to a Cannabinoid Pharmacophore Brian F. Thomas, Irma B. Adams, S. Wayne Mascarella et al. · Journal of Medicinal Chemistry 1996 88
25 G Protein-coupled Endothelial Receptor for Atypical Cannabinoid Ligands Modulates a Ca2+-dependent K+ Current Malcolm Begg, Fong-Ming Mo, László Offertáler et al. · Journal of Biological Chemistry Open access Nov 2003 86
26 Targeting multiple cannabinoid anti‐tumour pathways with a resorcinol derivative leads to inhibition of advanced stages of breast cancer Ryuichi Murase, Rumi Kawamura, Eric A. Singer et al. · British Journal of Pharmacology Open access 9 Jun 2014 84
27 Neurobehavioral activity in mice of N-vanillyl-arachidonyl-amide Vincenzo Di Marzo, Christopher S. Breivogel, Tiziana Bisogno et al. · European Journal of Pharmacology Open access Oct 2000 81
28 SAR of psilocybin analogs: Discovery of a selective 5-HT2C agonist Howard Sard, Govindaraj Kumaran, Cynthia Morency et al. · Bioorganic & Medicinal Chemistry Letters Open access 3 Aug 2005 80
29 2-Carbomethoxy-3-aryl-8-oxabicyclo[3.2.1]octanes: Potent Non-Nitrogen Inhibitors of Monoamine Transporters Peter C. Meltzer, Anna Y. Liang, Paul Blundell et al. · Journal of Medicinal Chemistry Open access Aug 1997 80
30 Inhibition of Cytosolic Phospholipase A2α: Hit to Lead Optimization John C. McKew, Megan A. Foley, Paresh Thakker et al. · Journal of Medicinal Chemistry Open access 8 Dec 2005 77
31 6ʺ-Azidohex-2ʺ-yne-cannabidiol: a potential neutral, competitive cannabinoid CB1 receptor antagonist Adèle Thomas, Ruth A. Ross, Bijali Saha et al. · European Journal of Pharmacology 11 Feb 2004 77
32 Asexual Populations of the Human Malaria Parasite, Plasmodium falciparum, Use a Two-Step Genomic Strategy to Acquire Accurate, Beneficial DNA Amplifications Jennifer L. Güler, D.L. Freeman, Vida Ahyong et al. · PLoS Pathogens Open access 23 May 2013 77
33 A general method for C3 reductive alkylation of indoles Anu Mahadevan, Howard Sard, Mario Daniel Gonzalez et al. · Tetrahedron Letters 19 May 2003 71
34 A novel fluorophosphonate inhibitor of the biosynthesis of the endocannabinoid 2‐arachidonoylglycerol with potential anti‐obesity effects Tiziana Bisogno, Anu Mahadevan, Roberto Coccurello et al. · British Journal of Pharmacology Open access 17 Oct 2012 71
35 Novel Cannabinol Probes for CB1 and CB2 Cannabinoid Receptors Anu Mahadevan, Craig Siegel, Billy R. Martin et al. · Journal of Medicinal Chemistry Open access 9 Sep 2000 71
36 Pharmacological and behavioral evaluation of alkylated anandamide analogs Irma B. Adams, William J. Ryan, Michael I. Singer et al. · Life Sciences May 1995 70
37 Technepine: A high-affinity99mtechnetium probe to label the dopamine transporter in brain by SPECT imaging Bertha Kalifon Madras, Alun Gwynne Jones, Ashfaq Mahmood et al. · Synapse Mar 1996 68
38 New potent and selective inhibitors of anandamide reuptake with antispastic activity in a mouse model of multiple sclerosis Alessia Ligresti, Maria Grazia Cascio, Gareth Pryce et al. · British Journal of Pharmacology Open access 14 Nov 2005 66
39 O‐1057, a potent water‐soluble cannabinoid receptor agonist with antinociceptive properties Roger G. Pertwee, Thomas M. Gibson, Lesley Stevenson et al. · British Journal of Pharmacology Open access Apr 2000 65
40 Sensitivity to Δ9-tetrahydrocannabinol is selectively enhanced in beta-arrestin2−/− mice Christopher S. Breivogel, Jonathan M. Lambert, Steven Gerfin et al. · Behavioural Pharmacology Open access Jul 2008 62
41 Nitrogen-based drugs are not essential for blockade of monoamine transporters Bertha Kalifon Madras, Zdenek B. Pristupa, Hyman B. Niznik et al. · Synapse Dec 1996 62
42 Potent Anandamide Analogs: The Effect of Changing the Length and Branching of the End Pentyl Chain William J. Ryan, W. Kenneth Banner, Jenny L. Wiley et al. · Journal of Medicinal Chemistry Open access Oct 1997 61
43 2-Carbomethoxy-3-aryl-8-bicyclo[3.2.1]octanes: Potent Non-Nitrogen Inhibitors of Monoamine Transporters Peter C. Meltzer, Paul Blundell, Yaw Fui Yong et al. · Journal of Medicinal Chemistry 15 Jul 2000 59
44 Evaluation of prevalent phytocannabinoids in the acetic acid model of visceral nociception Lamont Booker, Pattipati S. Naidu, Raj K. Razdan et al. · Drug and Alcohol Dependence Open access 13 Aug 2009 59
45 [11C,127I] Altropane: A highly selective ligand for PET imaging of dopamine transporter sites Alan J. Fischman, Ali A. Bonab, John W. Babich et al. · Synapse 2001 59
46 Structural determinants of the partial agonist‐inverse agonist properties of 6′‐azidohex‐2′‐yne‐Δ8‐tetrahydrocannabinol at cannabinoid receptors Ruth A. Ross, Thomas M. Gibson, Lesley Stevenson et al. · British Journal of Pharmacology Open access Oct 1999 58
47 Evaluation of Cannabimimetic Discriminative Stimulus Effects of Anandamide and Methylated Fluoroanandamide in Rhesus Monkeys Jenny L. Wiley, Keith M. Golden, William J. Ryan et al. · Pharmacology Biochemistry and Behavior Dec 1997 54
48 Altropane, a SPECT or PET imaging probe for dopamine neurons: III. Human dopamine transporter in postmortem normal and Parkinson's diseased brain Bertha Kalifon Madras, Lawrence M. Gracz, Michele A. Fahey et al. · Synapse Jun 1998 54
49 A Technetium-99m SPECT Imaging Agent Which Targets the Dopamine Transporter in Primate Brain Peter C. Meltzer, Paul Blundell, Alun Gwynne Jones et al. · Journal of Medicinal Chemistry Open access Jun 1997 54
50 SR-141716A-induced stimulation of locomotor activity Caroline E. Bass, Graeme Griffin, Mark C. Grier et al. · Pharmacology Biochemistry and Behavior 30 Oct 2002 52

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.