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Most cited papers from Orthopedic Institute

What are the most cited papers from Orthopedic Institute?

The most cited paper from Orthopedic Institute is "Implant infections: adhesion, biofilm formation and immune evasion" (Carla Renata Arciola, Davide Campoccia, Lucio Montanaro, 2018), with 2,274 citations. Next come "3D tumor spheroid models for in vitro therapeutic screening: a systematic approach to enhance the biological relevance of data obtained" (1,156) and "Biofilm formation in Staphylococcus implant infections. A review of molecular mechanisms and implications for biofilm-resistant materials" (1,053).

Showing 50 of 60 papers. Every paper with more than 219 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Implant infections: adhesion, biofilm formation and immune evasion Carla Renata Arciola, Davide Campoccia, Lucio Montanaro · Nature Reviews Microbiology Review 2 May 2018 2,274
2 3D tumor spheroid models for in vitro therapeutic screening: a systematic approach to enhance the biological relevance of data obtained Michele Zanoni, Filippo Piccinini, Chiara Arienti et al. · Scientific Reports Open access 11 Jan 2016 1,156
3 Biofilm formation in Staphylococcus implant infections. A review of molecular mechanisms and implications for biofilm-resistant materials Carla Renata Arciola, Davide Campoccia, Pietro Speziale et al. · Biomaterials 13 Jun 2012 1,053
4 Dissemination of Wear Particles to the Liver, Spleen, and Abdominal Lymph Nodes of Patients with Hip or Knee Replacement* Robert M. Urban, Joshua James Jacobs, Michael J. Tomlinson et al. · Journal of Bone and Joint Surgery Apr 2000 791
5 Burden of 375 diseases and injuries, risk-attributable burden of 88 risk factors, and healthy life expectancy in 204 countries and territories, including 660 subnational locations, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023 Simon I Hay et al. · The Lancet Open access2,780 authors Oct 2025 762
6 Nosology and classification of genetic skeletal disorders: 2019 revision Geert R. Mortier, Daniel H. Cohn, Valérie Cormier‐Daire et al. · American Journal of Medical Genetics Part A 21 Oct 2019 624
7 Ranawat Award Paper: Predicting Total Knee Replacement Pain Victoria Anne Brander, S. David Stulberg, Angela D. Adams et al. · Clinical Orthopaedics and Related Research Nov 2003 610
8 Platelet‐Rich Plasma Intra‐Articular Injection Versus Hyaluronic Acid Viscosupplementation as Treatments for Cartilage Pathology: From Early Degeneration to Osteoarthritis Elizaveta Kon, Bert R. Mandelbaum, Roberto Buda et al. · Arthroscopy The Journal of Arthroscopic and Related Surgery 11 Aug 2011 584
9 Platelet‐rich plasma: intra‐articular knee injections produced favorable results on degenerative cartilage lesions Elizaveta Kon, Roberto Buda, Giuseppe Filardo et al. · Knee Surgery Sports Traumatology Arthroscopy 16 Oct 2009 576
10 Nosology and classification of genetic skeletal disorders: 2015 revision Luisa Bonafé, Valérie Cormier‐Daire, Christine M Hall et al. · American Journal of Medical Genetics Part A 23 Sep 2015 573
11 Mandibuloacral Dysplasia Is Caused by a Mutation in LMNA-Encoding Lamin A/C Giuseppe Novelli, Antoine Muchir, Federica Carla Sangiuolo et al. · The American Journal of Human Genetics Open access Aug 2002 546
12 Optimizing dentin bond durability: Control of collagen degradation by matrix metalloproteinases and cysteine cathepsins Leo Tjäderhane, Fábio Dupart Nascimento, Lorenzo Breschi et al. · Dental Materials Open access 16 Aug 2012 533
13 Osteosarcoma (Osteogenic sarcoma) Piero Picci · Orphanet Journal of Rare Diseases Open access 23 Jan 2007 526
14 Allograft Versus Autograft Anterior Cruciate Ligament Reconstruction Christopher C. Kaeding, Brian Aros, Angela D. Pedroza et al. · Sports Health A Multidisciplinary Approach Open access 12 Oct 2010 525
15 Global burden of 292 causes of death in 204 countries and territories and 660 subnational locations, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023 Mohsen Naghavi et al. · The Lancet Open access2,463 authors Oct 2025 500
16 Presence of icaA and icaD Genes and Slime Production in a Collection of Staphylococcal Strains from Catheter-Associated Infections Carla Renata Arciola, Lucilla Baldassarri, Lucio Montanaro · Journal of Clinical Microbiology Open access Jun 2001 498
17 Platelet‐rich plasma intra‐articular knee injections for the treatment of degenerative cartilage lesions and osteoarthritis Giuseppe Filardo, Elizaveta Kon, Roberto Buda et al. · Knee Surgery Sports Traumatology Arthroscopy Open access 25 Aug 2010 476
18 Polysaccharide intercellular adhesin in biofilm: structural and regulatory aspects Carla Renata Arciola, Davide Campoccia, Stefano Ravaioli et al. · Frontiers in Cellular and Infection Microbiology Open access 10 Feb 2015 468
19 Biomechanical considerations in the pathogenesis of osteoarthritis of the knee Andras Heijink, Andreas H. Gomoll, Henning Madry et al. · Knee Surgery Sports Traumatology Arthroscopy Open access 15 Dec 2011 424
20 Operative Treatment of Femoral Neck Fractures in Patients Between the Ages of Fifteen and Fifty Years George John Haidukewych, Walter S. Rothwell, David Jacofsky et al. · Journal of Bone and Joint Surgery Aug 2004 420
21 Platelet‐rich plasma intra‐articular injections for cartilage degeneration and osteoarthritis: single‐ versus double‐spinning approach Giuseppe Filardo, Elizaveta Kon, Maria Teresa Pereira Ruiz et al. · Knee Surgery Sports Traumatology Arthroscopy 27 Dec 2011 413
22 Platelet-rich plasma vs hyaluronic acid to treat knee degenerative pathology: study design and preliminary results of a randomized controlled trial Giuseppe Filardo, Elizaveta Kon, Alessandro Di Martino et al. · BMC Musculoskeletal Disorders Open access 23 Nov 2012 390
23 Conservative Treatment of Plantar Heel Pain: Long-Term Follow-Up Mark Wolgin, Charles H. Cook, Charles E. Graham et al. · Foot & Ankle International Mar 1994 387
24 Interleukin 3- receptor targeted exosomes inhibit in vitro and in vivo Chronic Myelogenous Leukemia cell growth Daniele Bellavia, Stefania Raimondo, Giovanna Calabrese et al. · Theranostics Open access 2017 382
25 Platelet-Rich Plasma Intra-articular Knee Injections Show No Superiority Versus Viscosupplementation Giuseppe Filardo, Berardo Di Matteo, Alessandro Di Martino et al. · The American Journal of Sports Medicine 7 May 2015 368
26 Xenograft Versus Extraction Alone for Ridge Preservation After Tooth Removal: A Clinical and Histomorphometric Study Antonio Alci Barone, N. Nicoli Aldini, Milena Fini et al. · Journal of Periodontology Aug 2008 367
27 The Use of a Surgical Grade Calcium Sulfate as a Bone Graft Substitute Cynthia M. Kelly, Ross M. Wilkins, Steven Gitelis et al. · Clinical Orthopaedics and Related Research 2001 359
28 Molecular definition and sequence motifs of the 52-kD component of human SS-A/Ro autoantigen. Edward K. L. Chan, John C. Hamel, Jill P. Buyon et al. · Journal of Clinical Investigation Open access 1991 328
29 Use of platelet-rich plasma for the treatment of refractory jumper’s knee Giuseppe Filardo, Elizaveta Kon, Stefano Della Villa et al. · International Orthopaedics Open access 30 Jul 2009 324
30 THE JOHN INSALL AWARD: Pain and Depression Influence Outcome 5 Years after Knee Replacement Surgery Victoria Anne Brander, Stephen P. Gondek, Emily Jean Martin et al. · Clinical Orthopaedics and Related Research 29 Jun 2007 323
31 Aneurysmal Bone Cyst of the Mobile Spine Stefano Boriani, Federico De Iure, Laura Campanacci et al. · Spine 2001 311
32 Metabolic and Endocrine Abnormalities in Patients With Nonunions Mark R. Brinker, Daniel P. O’Connor, Yomna T Monla et al. · Journal of Orthopaedic Trauma Sep 2007 310
33 A Prospective, Randomized, Multicenter Food and Drug Administration Investigational Device Exemption Study of Lumbar Total Disc Replacement With the CHARITÉ ™ Artificial Disc Versus Lumbar Fusion Paul C. McAfee, Bryan W. Cunningham, Gwen A. Holsapple et al. · Spine Jul 2005 308
34 Early osteoarthritis of the knee Henning Madry, Elizaveta Kon, Vincenzo Condello et al. · Knee Surgery Sports Traumatology Arthroscopy 21 Mar 2016 306
35 Relationship of chemotherapy-induced necrosis and surgical margins to local recurrence in osteosarcoma. Piero Picci, Luca Sangiorgi, Bruce T. Rougraff et al. · Journal of Clinical Oncology Dec 1994 306
36 Functional Safe Zone Is Superior to the Lewinnek Safe Zone for Total Hip Arthroplasty: Why the Lewinnek Safe Zone Is Not Always Predictive of Stability Taro Tezuka, Nathanael D. Heckmann, Russell J. Bodner et al. · The Journal of Arthroplasty 2 Nov 2018 292
37 DXA: Technical aspects and application Alberto Bazzocchi, Federico Ponti, Ugo Albisinni et al. · European Journal of Radiology 15 Apr 2016 286
38 The healing of confined critical size cancellous defects in the presence of silk fibroin hydrogel Milena Fini, Antonella Motta, Paola Torricelli et al. · Biomaterials 15 Dec 2004 285
39 Effect of Graft Choice on the Outcome of Revision Anterior Cruciate Ligament Reconstruction in the Multicenter ACL Revision Study (MARS) Cohort The MARS Group et al. · The American Journal of Sports Medicine Open access 30 Sep 2014 280
40 Definition and classification of early osteoarthritis of the knee Frank P. Luyten, Matteo Denti, Giuseppe Filardo et al. · Knee Surgery Sports Traumatology Arthroscopy Open access 7 Nov 2011 280
41 Systemic Safety of High-Dose Antibiotic-Loaded Cement Spacers after Resection of an Infected Total Knee Arthroplasty Bryan D. Springer, Gwo‐Chin Lee, Douglas R. Osmon et al. · Clinical Orthopaedics and Related Research Oct 2004 278
42 Current treatment strategies for inhibiting mTOR in cancer Francesca Chiarini, Camilla Evangelisti, James Andrew McCubrey et al. · Trends in Pharmacological Sciences ReviewOpen access 11 Dec 2014 276
43 Ketamine versus ECT for Nonpsychotic Treatment-Resistant Major Depression Amit N. Anand et al. · New England Journal of Medicine 24 May 2023 275
44 Platelet‐rich plasma: why intra‐articular? A systematic review of preclinical studies and clinical evidence on PRP for joint degeneration Giuseppe Filardo, Elizaveta Kon, Alice Roffi et al. · Knee Surgery Sports Traumatology Arthroscopy ReviewOpen access 25 Nov 2013 269
45 Denosumab in patients with giant-cell tumour of bone: a multicentre, open-label, phase 2 study Sant P. Chawla, Jean‐Yves Blay, Piotr Lukasz Rutkowski et al. · The Lancet Oncology 5 Nov 2019 257
46 Arthroscopic Superior Capsular Reconstruction With Acellular Dermal Allograft for the Treatment of Massive Irreparable Rotator Cuff Tears: Short‐Term Clinical Outcomes and the Radiographic Parameter of Superior Capsular Distance William T. Pennington, Brian A. Bartz, Joann M. Pauli et al. · Arthroscopy The Journal of Arthroscopic and Related Surgery 15 Feb 2018 256
47 Functional Performance Testing After Anterior Cruciate Ligament Reconstruction Geoffrey D. Abrams, Joshua David Harris, Anil Kumar Gupta et al. · Orthopaedic Journal of Sports Medicine Open access 2014 255
48 Platelet‐rich plasma (PRP) to treat sports injuries: evidence to support its use Elizaveta Kon, Giuseppe Filardo, Alessandro Di Martino et al. · Knee Surgery Sports Traumatology Arthroscopy 16 Nov 2010 255
49 Functional Outcomes Following Trauma-Related Lower-Extremity Amputation Ellen J. MacKenzie, Michael J. Bosse, Renan C. Castillo et al. · Journal of Bone and Joint Surgery Aug 2004 251
50 Cigarette Smoking Increases the Risk for Rotator Cuff Tears Keith M. Baumgarten, David Gerlach, Leesa M. Galatz et al. · Clinical Orthopaedics and Related Research Open access 12 Mar 2009 244

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.