Most cited papers from Otsuka (Japan)

Otsuka (Japan)

What are the most cited papers from Otsuka (Japan)?

The most cited paper from Otsuka (Japan) is "Paradoxical Decrease of an Adipose-Specific Protein, Adiponectin, in Obesity" (Yukio Arita, Shinji Kihara, Noriyuki Bob Ouchi et al., 1999), with 4,880 citations. Next come "Diet-induced insulin resistance in mice lacking adiponectin/ACRP30" (2,099) and "Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans" (1,766).

Published TypeFieldAccessAuthorsCitations

Showing 50 of 60 papers. Every paper with more than 347 citations is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	Paradoxical Decrease of an Adipose-Specific Protein, Adiponectin, in Obesity Yukio Arita, Shinji Kihara, Noriyuki Bob Ouchi et al. · Biochemical and Biophysical Research Communications	Apr 1999	4,880
2	Diet-induced insulin resistance in mice lacking adiponectin/ACRP30 Norikazu Maeda, Iichiro Shimomura, Ken Kishida et al. · Nature Medicine	17 Jun 2002	2,099
3	Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans Kimber L. Stanhope et al. · Journal of Clinical Investigation Open access	16 Apr 2009	1,766
4	Adiponectin, an Adipocyte-Derived Plasma Protein, Inhibits Endothelial NF-κB Signaling Through a cAMP-Dependent Pathway Noriyuki Bob Ouchi, Shinji Kihara, Yukio Arita et al. · Circulation	12 Sep 2000	1,743
5	Candida auris sp. nov., a novel ascomycetous yeast isolated from the external ear canal of an inpatient in a Japanese hospital Kazuo Satoh, Koichi Makimura, Yayoi Hasumi et al. · Microbiology and Immunology Open access	2009	1,417
6	Adipocyte-Derived Plasma Protein, Adiponectin, Suppresses Lipid Accumulation and Class A Scavenger Receptor Expression in Human Monocyte-Derived Macrophages Noriyuki Bob Ouchi, Shinji Kihara, Yukio Arita et al. · Circulation	27 Feb 2001	1,286
7	Modeling colorectal cancer using CRISPR-Cas9–mediated engineering of human intestinal organoids Mami Matano, Shoichi Date, Mariko Shimokawa et al. · Nature Medicine	23 Feb 2015	1,143
8	The power of genetic diversity in genome-wide association studies of lipids Sarah E. Graham et al. · Nature Open access527 authors	9 Dec 2021	1,099
9	Potentiometric Selectivity Coefficients of Ion-Selective Electrodes. Part I. Inorganic Cations (Technical Report) Yoshio Umezawa, Philippe Bühlmann, Kayoko Umezawa et al. · Pure and Applied Chemistry Open access	2000	1,099
10	A saturated map of common genetic variants associated with human height Loïc Yengo et al. · Nature Open access632 authors	12 Oct 2022	934
11	Complete sequencing and characterization of 21,243 full-length human cDNAs Toshio Ota et al. · Nature Genetics 157 authors	21 Dec 2003	934
12	Enhanced expression of PAI–1 in visceral fat: Possible contributor to vascular disease in obeisty Iichiro Shimomura, Tohru Funahasm, Masahiko Takahashi et al. · Nature Medicine	Jul 1996	897
13	Inflammasome Activation of Cardiac Fibroblasts Is Essential for Myocardial Ischemia/Reperfusion Injury Masanori Kawaguchi, Masafumi Takahashi, Takeki Hata et al. · Circulation	31 Jan 2011	887
14	A Colorectal Tumor Organoid Library Demonstrates Progressive Loss of Niche Factor Requirements during Tumorigenesis Masayuki Fujii, Mariko Shimokawa, Shoichi Date et al. · Cell stem cell Open access	21 May 2016	879
15	IL-4 induces adherence of human eosinophils and basophils but not neutrophils to endothelium. Association with expression of VCAM-1 Robert P. Schleimer, Sherry A. Sterbinsky, J.‐P. Kaiser et al. · The Journal of Immunology	Feb 1992	830
16	TAZ: a novel transcriptional co‐activator regulated by interactions with 14‐3‐3 and PDZ domain proteins Fumihiko Kanai, Paola A. Marignani, Dilara Sarbassova et al. · The EMBO Journal Open access	15 Dec 2000	771
17	Reverse search for enumeration David Avis, Komei Fukuda · Discrete Applied Mathematics Open access	Mar 1996	770
18	Visualization and targeting of LGR5+ human colon cancer stem cells Mariko Shimokawa, Yuki Ohta, Shingo Nishikori et al. · Nature	27 Mar 2017	765
19	OPC-67683, a Nitro-Dihydro-Imidazooxazole Derivative with Promising Action against Tuberculosis In Vitro and In Mice Makoto Matsumoto, Hiroyuki Hashizume, Tatsuo Tomishige et al. · PLoS Medicine Open access	22 Nov 2006	754
20	Adipocyte-Derived Plasma Protein Adiponectin Acts as a Platelet-Derived Growth Factor-BB–Binding Protein and Regulates Growth Factor–Induced Common Postreceptor Signal in Vascular Smooth Muscle Cell Yukio Arita, Shinji Kihara, Noriyuki Bob Ouchi et al. · Circulation Open access	18 Jun 2002	696
21	Adhesion of human basophils, eosinophils, and neutrophils to interleukin 1-activated human vascular endothelial cells: contributions of endothelial cell adhesion molecules. Bruce S. Bochner, Francis William Luscinskas, Michael A. Gimbrone et al. · The Journal of Experimental Medicine Open access	Jun 1991	666
22	Tough Physical Double‐Network Hydrogels Based on Amphiphilic Triblock Copolymers Hui Jie Zhang, Tao Lin Sun, Ao Kai Zhang et al. · Advanced Materials Open access	27 Apr 2016	610
23	Human Intestinal Organoids Maintain Self-Renewal Capacity and Cellular Diversity in Niche-Inspired Culture Condition Masayuki Fujii, Mami Matano, Kohta Toshimitsu et al. · Cell stem cell Open access	Dec 2018	583
24	An Adipocyte-Derived Plasma Protein, Adiponectin, Adheres to Injured Vascular Walls Yoshihisa Okamoto, Yutaka Arita, M. Nishida et al. · Hormone and Metabolic Research	Feb 2000	569
25	Purification and subunit structure of hepatocyte growth factor from rat platelets Toshikazu Nakamura, Katsuhiko Nawa, Akira Ichihara et al. · FEBS Letters	30 Nov 1987	554
26	Electron and photon performance measurements with the ATLAS detector using the 2015–2017 LHC proton-proton collision data G. Aad et al. · Journal of Instrumentation Open access2,048 authors	10 Dec 2019	533
27	Decreased Plasma Adiponectin Concentrations in Women with Dyslipidemia Miyao Matsubara, Shoji Maruoka, Shinji Katayose · The Journal of Clinical Endocrinology & Metabolism	Jun 2002	518
28	The antipsychotic aripiprazole is a potent, partial agonist at the human 5-HT1A receptor Shaun Jordan, Vuk Koprivica, Ruoyan Chen et al. · European Journal of Pharmacology	Apr 2002	514
29	Effect of particle size reduction on dissolution and oral absorption of a poorly water-soluble drug, cilostazol, in beagle dogs Jun-ichi Jinno, Naoki Kamada, Masateru Miyake et al. · Journal of Controlled Release	11 Jan 2006	510
30	Inverse relationship between plasma adiponectin and leptin concentrations in normal-weight and obese women M Matsubara, Shuichiro Maruoka, Shinji Katayose · European Journal of Endocrinology	Aug 2002	509
31	ARNOLD CONJECTURE AND GROMOV–WITTEN INVARIANT Kenji Fukaya, Kaoru Ono · Topology Open access	Sep 1999	500
32	Combined measurements of Higgs boson production and decay using up to 80 fb − 1 of proton-proton collision data at s = 13 TeV collected with the ATLAS experiment G. Aad et al. · Physical review. D/Physical review. D. Open access2,939 authors	3 Jan 2020	497
33	Clonal Hematopoiesis Associated With Adverse Outcomes After Autologous Stem-Cell Transplantation for Lymphoma Christopher James Gibson et al. · Journal of Clinical Oncology Open access	23 Feb 2017	483
34	Mechanotransduction in mouse inner ear hair cells requires transmembrane channel–like genes Yoshiyuki Kawashima, Gwenaëlle S. G. Géléoc, Kiyoto Kurima et al. · Journal of Clinical Investigation Open access	21 Nov 2011	481
35	Aripiprazole in the treatment of schizophrenia: safety and tolerability in short-term, placebo-controlled trials Stephen R. Marder, Robert D. McQuade, Elyse G. Stock et al. · Schizophrenia Research	May 2003	471
36	Gonadal sex differentiation in teleost fish Masaru Nakamura, Tohru Kobayashi, Xiaotian Chang et al. · Journal of Experimental Zoology	Aug 1998	454
37	ATLAS b-jet identification performance and efficiency measurement with $$t{\bar{t}}$$ events in pp collisions at $$\sqrt{s}=13$$ TeV G. Aad et al. · The European Physical Journal C Open access2,930 authors	Nov 2019	437
38	A detailed map of Higgs boson interactions by the ATLAS experiment ten years after the discovery G. Aad et al. · Nature Open access2,903 authors	4 Jul 2022	419
39	Involvement of IL-6 in mesangial proliferative glomerulonephritis. Yuko Horii, Atsushi Muraguchi, Masayuki Iwano et al. · The Journal of Immunology	Dec 1989	411
40	Plasma and brain pharmacokinetic profile of cannabidiol (CBD), cannabidivarine (CBDV), Δ9-tetrahydrocannabivarin (THCV) and cannabigerol (CBG) in rats and mice following oral and intraperitoneal administration and CBD action on obsessive–compulsive behaviour Serena Deiana, Akihito Watanabe, Yuki Yamasaki et al. · Psychopharmacology	27 Jul 2011	410
41	A pivoting algorithm for convex hulls and vertex enumeration of arrangements and polyhedra David Avis, Komei Fukuda · Discrete & Computational Geometry Open access	Aug 1992	407
42	Performance of electron and photon triggers in ATLAS during LHC Run 2 G. Aad et al. · The European Physical Journal C Open access2,949 authors	2020	406
43	The characteristics and chronology of the earliest Acheulean at Konso, Ethiopia Yonas Beyene, Shigehiro Katoh, Giday WoldeGabriel et al. · Proceedings of the National Academy of Sciences Open access	28 Jan 2013	405
44	Automated extraction of information on protein–protein interactions from the biological literature Toshihide Ono, Haretsugu Hishigaki, Akira Tanigami et al. · Bioinformatics Open access	Feb 2001	398
45	Tissue-specific mRNA Expression Profiles of Human ATP-binding Cassette and Solute Carrier Transporter Superfamilies Masuhiro Nishimura, Shinsaku Naito · Drug Metabolism and Pharmacokinetics	2005	391
46	Seven Direct Methods for Measuring HDL and LDL Cholesterol Compared with Ultracentrifugation Reference Measurement Procedures W. Greg Miller, Gary L. Myers, Ikunosuke Sakurabayashi et al. · Clinical Chemistry Open access	8 Apr 2010	386
47	Purine and Pyrimidine Nucleotide Synthesis and Metabolism Barbara A. Moffatt, Hiroshi Ashihara · The Arabidopsis Book Open access	2002	382
48	Muon reconstruction and identification efficiency in ATLAS using the full Run 2 pp collision data set at $$\sqrt{s}=13$$ TeV G. Aad et al. · The European Physical Journal C Open access2,936 authors	Jul 2021	381
49	An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells Ekaterina V. Vinogradova et al. · Cell Open access	29 Jul 2020	381
50	Genomic structure and mutations in adipose-specific gene, adiponectin Motoko Takahashi, Yutaka Arita, Kazuya Yamagata et al. · International Journal of Obesity	Jul 2000	378

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.