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Institution · Otsuka (United States)

Most cited papers from Otsuka (United States)

What are the most cited papers from Otsuka (United States)?

The most cited paper from Otsuka (United States) is "Tolvaptan in Patients with Autosomal Dominant Polycystic Kidney Disease" (Vicente E. Torres, Arlene B. Chapman, Olivier Devuyst et al., 2012), with 1,628 citations. Next come "Tolvaptan, a Selective Oral Vasopressin V 2 -Receptor Antagonist, for Hyponatremia" (1,221) and "Brain-derived Neurotrophic Factor Is Stored in Human Platelets and Released by Agonist Stimulation" (786).

Showing 50 of 60 papers. Every paper with more than 199 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Tolvaptan in Patients with Autosomal Dominant Polycystic Kidney Disease Vicente E. Torres, Arlene B. Chapman, Olivier Devuyst et al. · New England Journal of Medicine Open access 3 Nov 2012 1,628
2 Tolvaptan, a Selective Oral Vasopressin V 2 -Receptor Antagonist, for Hyponatremia Robert W. Schrier, Peter A. Gross, Mihai Gheorghiade et al. · New England Journal of Medicine Open access 14 Nov 2006 1,221
3 Brain-derived Neurotrophic Factor Is Stored in Human Platelets and Released by Agonist Stimulation Hironobu Fujimura, Ruoyan Chen, Takashi Nakamura et al. · Thrombosis and Haemostasis 2002 786
4 Delamanid for Multidrug-Resistant Pulmonary Tuberculosis Maria Tarcela Gler et al. · New England Journal of Medicine Open access 7 Jun 2012 748
5 NCCN Guidelines Insights: Non–Small Cell Lung Cancer, Version 4.2016 David S. Ettinger et al. · Journal of the National Comprehensive Cancer Network Open access Mar 2016 739
6 Lymphocyte interactions with endothelial cells Yoji Shimizu, Walter Newman, Yoshiya Tanaka et al. · Immunology Today Open access 1992 686
7 Evidence for the involvement of interleukin 6 in experimental cancer cachexia. Gideon Strassmann, M Fong, J S Kenney et al. · Journal of Clinical Investigation Open access May 1992 662
8 Tolvaptan in Later-Stage Autosomal Dominant Polycystic Kidney Disease Vicente E. Torres, Arlene B. Chapman, Olivier Devuyst et al. · New England Journal of Medicine Open access 4 Nov 2017 640
9 Efficacy and Safety of Aripiprazole and Haloperidol Versus Placebo in Patients With Schizophrenia and Schizoaffective Disorder John Michael Kane, William H. Carson, Anutosh Ranjan Saha et al. · The Journal of Clinical Psychiatry 15 Sep 2002 629
10 Aripiprazole in the Treatment of Irritability in Children and Adolescents With Autistic Disorder Randall Owen, Linmarie Sikich, Ronald N. Marcus et al. · PEDIATRICS 30 Nov 2009 616
11 A Placebo-Controlled, Fixed-Dose Study of Aripiprazole in Children and Adolescents With Irritability Associated With Autistic Disorder Ronald N. Marcus, Randall Owen, Lisa Kamen et al. · Journal of the American Academy of Child & Adolescent Psychiatry 14 Oct 2009 569
12 Neurotrophins and depression C. Anthony Altar · Trends in Pharmacological Sciences Review Feb 1999 537
13 The Efficacy and Safety of Aripiprazole as Adjunctive Therapy in Major Depressive Disorder Ronald N. Marcus, Robert D. McQuade, William H. Carson et al. · Journal of Clinical Psychopharmacology Apr 2008 519
14 The antipsychotic aripiprazole is a potent, partial agonist at the human 5-HT1A receptor Shaun Jordan, Vuk Koprivica, Ruoyan Chen et al. · European Journal of Pharmacology Apr 2002 514
15 The Economic Burden of Schizophrenia in the United States in 2013 Martin Cloutier, Myrlene Sanon Aigbogun, Annie Guérin et al. · The Journal of Clinical Psychiatry 25 Apr 2016 494
16 Aripiprazole in the treatment of schizophrenia: safety and tolerability in short-term, placebo-controlled trials Stephen R. Marder, Robert D. McQuade, Elyse G. Stock et al. · Schizophrenia Research May 2003 471
17 A comparison of cilostazol and pentoxifylline for treating intermittent claudication David L. Dawson, Bruce S. Cutler, William R. Hiatt et al. · The American Journal of Medicine Nov 2000 442
18 Vascular endothelial cells synthesize and secrete brain‐derived neurotrophic factor Takeshi Nakahashi, Hironobu Fujimura, C. Anthony Altar et al. · FEBS Letters Open access 20 Mar 2000 436
19 Vasopressin V 2 -Receptor Blockade With Tolvaptan in Patients With Chronic Heart Failure Mihai Gheorghiade, Imran Khan Niazi, John Ouyang et al. · Circulation 13 May 2003 430
20 Nabiximols for Opioid-Treated Cancer Patients With Poorly-Controlled Chronic Pain: A Randomized, Placebo-Controlled, Graded-Dose Trial Russell K. Portenoy, Elena Doina Ganae-Motan, Silvia Allende‐Pérez et al. · Journal of Pain Open access 5 Apr 2012 421
21 Triacylglycerol accumulation in human obesity and type 2 diabetes is associated with increased rates of skeletal muscle fatty acid transport and increased sarcolemmal FAT/CD36 Arend Bonen, Michelle L. Parolin, Gregory R. Steinberg et al. · The FASEB Journal 7 May 2004 410
22 Neuropsychiatric signs and symptoms of Alzheimer's disease: New treatment paradigms Krista L. Lanctôt, Joan C. Amatniek, Sonia Ancoli‐Israel et al. · Alzheimer s & Dementia Translational Research & Clinical Interventions Open access 5 Aug 2017 403
23 Choline Diet and Its Gut Microbe–Derived Metabolite, Trimethylamine N-Oxide, Exacerbate Pressure Overload–Induced Heart Failure Chelsea L. Organ, Hiroyuki Otsuka, Shashi Bhushan et al. · Circulation Heart Failure Open access 24 Dec 2015 392
24 Human recombinant monocyte chemotactic protein and other c-c chemokines bind and induce directional migration of dendritic cells in vitro Luo Ling Xu, M. Kim Warren, Wendy L. Rose et al. · Journal of Leukocyte Biology Sep 1996 381
25 Acute Regulation of Fatty Acid Uptake Involves the Cellular Redistribution of Fatty Acid Translocase Arend Bonen, Joost J.F.P. Luiken, Yoga Arumugam et al. · Journal of Biological Chemistry Open access May 2000 378
26 Evidence for the involvement of interleukin 10 in the differential deactivation of murine peritoneal macrophages by prostaglandin E2. Gideon Strassmann, Vina Patil-koota, F D Finkelman et al. · The Journal of Experimental Medicine Open access Dec 1994 369
27 Brexpiprazole I: In Vitro and In Vivo Characterization of a Novel Serotonin-Dopamine Activity Modulator Kenji Maeda, Haruhiko Sugino, Hitomi Akazawa et al. · Journal of Pharmacology and Experimental Therapeutics 20 Jun 2014 369
28 Aripiprazole Intramuscular Depot as Maintenance Treatment in Patients With Schizophrenia John Michael Kane, Raymond Sanchez, Pamela P. Perry et al. · The Journal of Clinical Psychiatry Open access 2 May 2012 362
29 Oral Tolvaptan Is Safe and Effective in Chronic Hyponatremia Tomás Berl, Friederike Quittnat-Pelletier, Joseph George Verbalis et al. · Journal of the American Society of Nephrology Open access 25 Feb 2010 352
30 BDNF Promotes the Regenerative Sprouting, But Not Survival, of Injured Serotonergic Axons in the Adult Rat Brain Laura A. Mamounas, C. Anthony Altar, Mary E. Blue et al. · Journal of Neuroscience Open access 15 Jan 2000 348
31 A multicenter, randomized, double-blind, controlled phase 3 trial of fixed-dose brexpiprazole for the treatment of adults with acute schizophrenia John Michael Kane, Aleksandar Skuban, John Ouyang et al. · Schizophrenia Research 12 Feb 2015 327
32 Neurotrophin trafficking by anterograde transport C. Anthony Altar, Peter S. DiStefano · Trends in Neurosciences Review Oct 1998 319
33 Efficacy and safety of aripiprazole vs. haloperidol for long-term maintenance treatment following acute relapse of schizophrenia Siegfried F. Kasper, Mark N. Lerman, Robert D. McQuade et al. · The International Journal of Neuropsychopharmacology Dec 2003 312
34 Meta-analysis of results from eight randomized, placebo-controlled trials on the effect of cilostazol on patients with intermittent claudication Paul Daniel Thompson, Richard Zimet, William P. Forbes et al. · The American Journal of Cardiology Review Dec 2002 312
35 Aripiprazole for the Prevention of Relapse in Stabilized Patients With Chronic Schizophrenia Teresa A. Pigott, William H. Carson, Anutosh Ranjan Saha et al. · The Journal of Clinical Psychiatry 15 Sep 2003 312
36 Adhesion through the LFA-1 (CD11a/CD18)-ICAM-1 (CD54) and the VLA-4 (CD49d)-VCAM-1 (CD106) pathways prevents apoptosis of germinal center B cells. Gerrit Koopman, Robert M. J. Keehnen, Ernst Lindhout et al. · The Journal of Immunology Apr 1994 311
37 Hyponatremia in cirrhosis: From pathogenesis to treatment† Pere Ginès, Tomás Berl, Mauro Bernardi et al. · Hepatology Open access Sep 1998 300
38 High-shear-stress-induced activation of platelets and microparticles enhances expression of cell adhesion molecules in THP-1 and endothelial cells Shosaku Nomura, Narendra N. Tandon, Takashi Nakamura et al. · Atherosclerosis Oct 2001 300
39 Genetic/Familial High-Risk Assessment: Breast and Ovarian, Version 2.2015 Mary B. Daly et al. · Journal of the National Comprehensive Cancer Network Feb 2016 295
40 A Randomized, Double-Blind, Placebo-Controlled 26-Week Trial of Aripiprazole in Recently Manic Patients With Bipolar I Disorder Paul E. Keck, Joseph R. Calabrese, Robert D. McQuade et al. · The Journal of Clinical Psychiatry 15 Apr 2006 290
41 Prevalence of post-traumatic stress disorder in the United States: a systematic literature review Jeffrey R Schein, Christy R. Houle, Annette Urganus et al. · Current Medical Research and Opinion ReviewOpen access 9 Sep 2021 283
42 Good Publication Practice (GPP) Guidelines for Company-Sponsored Biomedical Research: 2022 Update Lisa M DeTora, Dikran Toroser, Angela Sykes et al. · Annals of Internal Medicine 29 Aug 2022 270
43 Insulin Stimulates Long-Chain Fatty Acid Utilization by Rat Cardiac Myocytes Through Cellular Redistribution of FAT/CD36 Joost J.F.P. Luiken, Debby P.Y. Koonen, Jodil Willems et al. · Diabetes Oct 2002 262
44 The Economic Burden of Posttraumatic Stress Disorder in the United States From a Societal Perspective Lori L. Davis, Jeff R. Schein, Martin Cloutier et al. · The Journal of Clinical Psychiatry Open access 21 Apr 2022 260
45 A Novel Function for Fatty Acid Translocase (FAT)/CD36 Shannon E. Campbell, Narendra N. Tandon, Gebretateos Woldegiorgis et al. · Journal of Biological Chemistry Open access Jun 2004 259
46 Prevalence of autosomal dominant polycystic kidney disease in the European Union Cynthia J Willey, Jaime D. Blais, Anthony K Hall et al. · Nephrology Dialysis Transplantation Open access 20 Jun 2016 253
47 Switching patients to aripiprazole from other antipsychotic agents: a multicenter randomized study on behalf of the Aripiprazole Study Group, Daniel E. Casey, William H. Carson et al. · Psychopharmacology 28 Feb 2003 252
48 Aripiprazole Monotherapy in Nonpsychotic Bipolar I Depression Michael E. Thase, Alan Jonas, Arif Khan et al. · Journal of Clinical Psychopharmacology Feb 2008 252
49 Effect of Cilostazol on Treadmill Walking, Community‐Based Walking Ability, and Health‐Related Quality of Life in Patients with Intermittent Claudication Due to Peripheral Arterial Disease: Meta‐Analysis of Six Randomized Controlled Trials Judith G. Regensteiner, John E. Ware, Walter J. McCarthy et al. · Journal of the American Geriatrics Society Dec 2002 252
50 Aripiprazole in the treatment of acute manic or mixed episodes in patients with bipolar I disorder: a 3-week placebo-controlled study Gary S. Sachs, Raymond Sanchez, Ronald N. Marcus et al. · Journal of Psychopharmacology 14 Feb 2006 251

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.