Most cited papers from Oxagen (United Kingdom)

Oxagen (United Kingdom)

What are the most cited papers from Oxagen (United Kingdom)?

The most cited paper from Oxagen (United Kingdom) is "A Human Homolog of Yeast Pre-mRNA Splicing Gene, PRP31, Underlies Autosomal Dominant Retinitis Pigmentosa on Chromosome 19q13.4 (RP11)" (Eranga N. Vithana, Leen Abu‐Safieh, Maxine Allen et al., 2001), with 336 citations. Next come "Extent and Distribution of Linkage Disequilibrium in Three Genomic Regions" (332) and "Positional cloning of a novel gene influencing asthma from Chromosome 2q14" (328).

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Showing 50 of 89 papers. Every paper is listed.

Most cited papers, sortable by citations and release date
#	Paper
1	A Human Homolog of Yeast Pre-mRNA Splicing Gene, PRP31, Underlies Autosomal Dominant Retinitis Pigmentosa on Chromosome 19q13.4 (RP11) Eranga N. Vithana, Leen Abu‐Safieh, Maxine Allen et al. · Molecular Cell Open access	Aug 2001	336
2	Extent and Distribution of Linkage Disequilibrium in Three Genomic Regions Gonçalo R. Abecasis, Emiko Noguchi, Andrea Heinzmann et al. · The American Journal of Human Genetics Open access	2001	332
3	Positional cloning of a novel gene influencing asthma from Chromosome 2q14 Maxine Allen et al. · Nature Genetics	19 Oct 2003	328
4	Association between a complex insertion/deletion polymorphism in NOD1 (CARD4) and susceptibility to inflammatory bowel disease Dermot P.B. McGovern, Pirro G. Hysi, Tariq Ahmad et al. · Human Molecular Genetics	24 Mar 2005	318
5	Antagonism of the prostaglandin D2 receptors DP1 and CRTH2 as an approach to treat allergic diseases Roy Pettipher, Trevor T. Hansel, Richard E Armer · Nature Reviews Drug Discovery Review	30 Mar 2007	318
6	Prostaglandin D2 Causes Preferential Induction of Proinflammatory Th2 Cytokine Production through an Action on Chemoattractant Receptor-Like Molecule Expressed on Th2 Cells Luzheng Xue, Shân L. Gyles, Frank R. Wettey et al. · The Journal of Immunology	Nov 2005	267
7	The Association between Common Vitamin D Receptor Gene Variations and Osteoporosis: A Participant-Level Meta-Analysis André Gerardus Uitterlinden et al. · Annals of Internal Medicine Open access	15 Aug 2006	251
8	Alpha-B Crystallin Gene (CRYAB) Mutation Causes Dominant Congenital Posterior Polar Cataract in Humans Vanita Berry, Peter J. Francis, M. Ashwin Reddy et al. · The American Journal of Human Genetics Open access	Nov 2001	233
9	Remapping the Insulin Gene/IDDM2 Locus in Type 1 Diabetes Bryan J. Barratt et al. · Diabetes	Jul 2004	224
10	A randomized, double‐blind, placebo‐controlled study of the CRTH2 antagonist OC000459 in moderate persistent asthma N. Barnes, Ian Douglas Pavord, А. Г. Чучалин et al. · Clinical & Experimental Allergy Open access	15 Jul 2011	219
11	DNA variation and the future of human genetics Alan J. Schafer, J. Ross Hawkins · Nature Biotechnology	1998	211
12	Anti‐eosinophil activity and clinical efficacy of the CRTH 2 antagonist OC 000459 in eosinophilic esophagitis Alex Straumann, S. Hoesli, Ch. Bussmann et al. · Allergy	5 Feb 2013	208
13	Genomewide Linkage Study in 1,176 Affected Sister Pair Families Identifies a Significant Susceptibility Locus for Endometriosis on Chromosome 10q26 Susan A. Treloar, Jacqueline Wicks, Dale R. Nyholt et al. · The American Journal of Human Genetics Open access	4 Aug 2005	195
14	Large-Scale Evidence for the Effect of the COLIA1 Sp1 Polymorphism on Osteoporosis Outcomes: The GENOMOS Study Stuart H. Ralston et al. · PLoS Medicine Open access	14 Feb 2006	183
15	Likelihood-Based Estimation of Microsatellite Mutation Rates John C. Whittaker, Roger M. Harbord, Nicola Boxall et al. · Genetics	Jun 2003	182
16	Association of the TSHR gene with Graves' disease: the first disease specific locus Bryan M. DeChairo, Delilah Zabaneh, Joanne E. Collins et al. · European Journal of Human Genetics	17 Aug 2005	179
17	The roles of the prostaglandin D2receptors DP1and CRTH2 in promoting allergic responses Roy Pettipher · British Journal of Pharmacology Open access	29 Oct 2007	166
18	The insulin gene VNTR, type 2 diabetes and birth weight Ken K. Ong, David I. Phillips, Caroline H. D. Fall et al. · Nature Genetics	Mar 1999	159
19	Loci for regulation of bone mineral density in men and women identified by genome wide linkage scan: the FAMOS study Stuart H. Ralston, Nick W. Galwey, Ian Mackay et al. · Human Molecular Genetics	3 Mar 2005	137
20	The Effect of Genetic Drift in a Young Genetically Isolated Population Luba Milena Pardo, Ian Mackay, Ben A. Oostra et al. · Annals of Human Genetics	21 Apr 2005	136
21	Linkage disequilibrium in young genetically isolated Dutch population Yurii S. Aulchenko, Peter Heutink, Ian Mackay et al. · European Journal of Human Genetics Open access	31 Mar 2004	122
22	Genomewide Search in Familial Paget Disease of Bone Shows Evidence of Genetic Heterogeneity with Candidate Loci on Chromosomes 2q36, 10p13, and 5q35 Lynne J. Hocking, Craig A. Herbert, Rosie K. Nicholls et al. · The American Journal of Human Genetics Open access	Nov 2001	117
23	Clinical features in women with polycystic ovaries: relationships to insulin sensitivity, insulin gene VNTR and birth weight Katherine F. Michelmore, Ken K. Ong, S.A. MASON et al. · Clinical Endocrinology	Oct 2001	113
24	Analysis of the IBD5 locus and potential gene-gene interactions in Crohn’s disease Kenichi Negoro, D P B McGovern, Y Kinouchi et al. · Gut Open access	11 Mar 2003	110
25	Inhibition of the asthmatic allergen challenge response by the CRTH2 antagonist OC000459 Dave Singh, Paul Cadden, Michael Hunter et al. · European Respiratory Journal Open access	10 Apr 2012	103
26	LPIN2 Is Associated With Type 2 Diabetes, Glucose Metabolism, and Body Composition Yurii S. Aulchenko, Jan Pullen, Wigard P. Kloosterman et al. · Diabetes Open access	6 Sep 2007	102
27	Large-scale analysis of association between polymorphisms in the transforming growth factor beta 1 gene (TGFB1) and osteoporosis: The GENOMOS study Bente Lomholt Langdahl et al. · Bone	5 Dec 2007	95
28	Identification of a Ras GTPase‐activating protein regulated by receptor‐mediated Ca2+ oscillations Simon A. Walker, Sabine Kupzig, Dalila Bouyoucef et al. · The EMBO Journal Open access	Apr 2004	92
29	Genome-Wide Mapping of Susceptibility to Coronary Artery Disease Identifies a Novel Replicated Locus on Chromosome 17 Martin Farrall, Fiona R. Green, John F. Peden et al. · PLoS Genetics Open access	16 May 2006	88
30	A Genome-Wide Screen in 1119 Relative Pairs with Autoimmune Thyroid Disease Jenny C. Taylor, Stephen C. L. Gough, P. J. Hunt et al. · The Journal of Clinical Endocrinology & Metabolism	Feb 2006	85
31	The CRTH 2 antagonist OC 000459 reduces nasal and ocular symptoms in allergic subjects exposed to grass pollen, a randomised, placebo‐controlled, double‐blind trial Friedrich Horak, Petra Ursula Zieglmayer, René Zieglmayer et al. · Allergy	Oct 2012	85
32	Replication and extension studies of inflammatory bowel disease susceptibility regions confirm linkage to chromosome 6p (IBD3) Bryan M. DeChairo, Claire Dimon, David A. van Heel et al. · European Journal of Human Genetics	Aug 2001	79
33	Novel Function of CRTH2 in Preventing Apoptosis of Human Th2 Cells through Activation of the Phosphatidylinositol 3-Kinase Pathway Luzheng Xue, Anna Barrow, Roy Pettipher · The Journal of Immunology Open access	Jun 2009	77
34	Update on the Development of Antagonists of Chemoattractant Receptor-Homologous Molecule Expressed on Th2 Cells (CRTH2). From Lead Optimization to Clinical Proof-of-Concept in Asthma and Allergic Rhinitis Roy Pettipher, Mark A. Whittaker · Journal of Medicinal Chemistry Open access	6 Jan 2012	75
35	Evidence for a Major Gene for Bone Mineral Density in Idiopathic Osteoporotic Families Lon R. Cardon, C. Garner, S. T. Bennett et al. · Journal of Bone and Mineral Research	Jun 2000	69
36	A Genome-Wide Screen for Asthma-Associated Quantitative Trait Loci in a Mouse Model of Allergic Asthma Ying Zhang, J. Lefort, V. Kearsey et al. · Human Molecular Genetics	Apr 1999	66
37	Pharmacologic Profile of OC000459, a Potent, Selective, and Orally Active D Prostanoid Receptor 2 Antagonist That Inhibits Mast Cell-Dependent Activation of T Helper 2 Lymphocytes and Eosinophils Roy Pettipher, Shân L. Vinall, Luzheng Xue et al. · Journal of Pharmacology and Experimental Therapeutics	22 Nov 2011	66
38	Significant evidence of one or more susceptibility loci for endometriosis with near-Mendelian inheritance on chromosome 7p13–15 Krina T. Zondervan, Susan A. Treloar, Jianghai Lin et al. · Human Reproduction	11 Dec 2006	62
39	Inflammatory Bowel Disease Is Linked to 19p13 and Associated with ICAM-1 Jin Hong Low, Fiona A. Williams, Yang Xuesong et al. · Inflammatory Bowel Diseases	21 Apr 2004	60
40	A gene for ataxic cerebral palsy maps to chromosome 9p12–q12 DP McHale, Andrew P. Jackson, Donald Campbell et al. · European Journal of Human Genetics	Apr 2000	52
41	Efficiencies of F2 and Backcross Generations for Bulked Segregant Analysis Using Dominant Markers Ian Mackay, Peter D.S. Caligari · Crop Science	May 2000	48
42	A dominant role for chemoattractant receptor‐homologous molecule expressed on T helper type 2 (Th2) cells (CRTH2) in mediating chemotaxis of CRTH2+ CD4+ Th2 lymphocytes in response to mast cell supernatants Shân L. Gyles, Luzheng Xue, Elizabeth R. Townsend et al. · Immunology Open access	8 Aug 2006	48
43	Δ12-Prostaglandin D2 is a potent and selective CRTH2 receptor agonist and causes activation of human eosinophils and Th2 lymphocytes Lucien Gazi, Shân L. Gyles, Jennifer Rose et al. · Prostaglandins & Other Lipid Mediators	2005	47
44	Inflammatory Bowel Disease: Progress Towards a Gene David A. van Heel, Jack Satsangi, Alisoun H. Carey et al. · Canadian Journal of Gastroenterology Open access	2000	47
45	Antagonists of the Prostaglandin D2 Receptor CRTH2 Roy Pettipher, Trevor T. Hansel · Drug News & Perspectives	2008	46
46	Affected sib-pair analysis in endometriosis Stephen Kennedy, Simon T. Bennett, Daniel E. Weeks · Human Reproduction Update	Jul 2001	45
47	Leukotriene E4 Activates Human Th2 Cells for Exaggerated Proinflammatory Cytokine Production in Response to Prostaglandin D2 Luzheng Xue, Anna Barrow, Vicki M. Fleming et al. · The Journal of Immunology Open access	15 Dec 2011	44
48	Inhibition of PI3K and calcineurin suppresses chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2)-dependent responses of Th2 lymphocytes to prostaglandin D2 Luzheng Xue, Shân L. Gyles, Anna Barrow et al. · Biochemical Pharmacology	2 Dec 2006	44
49	Interaction between prostaglandin D2 and chemoattractant receptor-homologous molecule expressed on Th2 cells mediates cytokine production by Th2 lymphocytes in response to activated mast cells Luzheng Xue, Anna Barrow, Roy Pettipher · Clinical & Experimental Immunology Open access	11 Feb 2009	42
50	Simulations of amphiphilic fluids using mesoscale lattice-Boltzmann and lattice-gas methods Peter J. Love, Maziar Nekovee, Peter V. Coveney et al. · Computer Physics Communications Open access	19 May 2003	42

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.