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Most cited papers from Personalis (United States)

What are the most cited papers from Personalis (United States)?

The most cited paper from Personalis (United States) is "A global reference for human genetic variation" (Corresponding authors et al., 2015), with 20,444 citations. Next come "Circulating Tumor DNA Analysis Guiding Adjuvant Therapy in Stage II Colon Cancer" (1,076) and "Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Pharmacogenetics‐Guided Warfarin Dosing: 2017 Update" (724).

Showing 50 of 60 papers. Every paper with more than 34 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 A global reference for human genetic variation Corresponding authors et al. · Nature Open access815 authors 29 Sep 2015 20,444
2 Circulating Tumor DNA Analysis Guiding Adjuvant Therapy in Stage II Colon Cancer Jeanne Tie et al. · New England Journal of Medicine Open access 4 Jun 2022 1,076
3 Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Pharmacogenetics‐Guided Warfarin Dosing: 2017 Update JA Johnson, KE Caudle, Li Gong et al. · Clinical Pharmacology & Therapeutics Open access 15 Feb 2017 724
4 Characterizing the genetic basis of transcriptome diversity through RNA-sequencing of 922 individuals Alexis J. Battle, Sara Mostafavi, Xiaowei Zhu et al. · Genome Research Open access 3 Oct 2013 651
5 Tolerance of Whole-Genome Doubling Propagates Chromosomal Instability and Accelerates Cancer Genome Evolution Sally M. Dewhurst, Nicholas McGranahan, Rebecca A. Burrell et al. · Cancer Discovery Open access 16 Jan 2014 490
6 Sotigalimab and/or nivolumab with chemotherapy in first-line metastatic pancreatic cancer: clinical and immunologic analyses from the randomized phase 2 PRINCE trial Lacey Padrón et al. · Nature Medicine Open access Jun 2022 381
7 CD40 agonistic monoclonal antibody APX005M (sotigalimab) and chemotherapy, with or without nivolumab, for the treatment of metastatic pancreatic adenocarcinoma: an open-label, multicentre, phase 1b study Mark H. O’Hara et al. · The Lancet Oncology 30 Dec 2020 311
8 Identifying who has long COVID in the USA: a machine learning approach using N3C data Emily Pfaff et al. · The Lancet Digital Health Open access 16 May 2022 278
9 Personalized neoantigen vaccine and pembrolizumab in advanced hepatocellular carcinoma: a phase 1/2 trial Mark M. Yarchoan, Edward John Gane, Thomas Urban Marron et al. · Nature Medicine Open access Apr 2024 249
10 A public resource facilitating clinical use of genomes Mad Price Ball et al. · Proceedings of the National Academy of Sciences Open access 13 Jul 2012 247
11 Circulating tumor DNA as a potential marker of adjuvant chemotherapy benefit following surgery for localized pancreatic cancer Belinda Lee et al. · Annals of Oncology Open access 25 Jun 2019 219
12 Extending reference assembly models Deanna M. Church, Valérie Schneider, Karyn Meltz Steinberg et al. · Genome biology Open access 23 Jan 2015 204
13 Effects of isoflurane anesthesia on the cardiovascular function of the C57BL/6 mouse. Christakis Constantinides, Richard James Mean, Ben J. Janssen · PubMed Open access 2011 202
14 Type I interferon signaling genes in recurrent major depression: increased expression detected by whole-blood RNA sequencing Sara Mostafavi et al. · Molecular Psychiatry Open access 3 Dec 2013 194
15 DNA–bare gold affinity interactions: mechanism and applications in biosensing Kevin M. Koo, Abu Ali Ibn Sina, Laura Garcia Carrascosa et al. · Analytical Methods 2015 177
16 A panel data analysis of the impact of trade on human development Antony N. Davies, Gary Quinlivan · The Journal of Socio-Economics 27 Jan 2006 161
17 Imaging vascular function for early stage clinical trials using dynamic contrast-enhanced magnetic resonance imaging Martin O. Leach et al. · European Radiology 6 May 2012 153
18 Single haplotype assembly of the human genome from a hydatidiform mole Karyn Meltz Steinberg, Valérie Schneider, Tina A. Graves-Lindsay et al. · Genome Research Open access 4 Nov 2014 150
19 svclassify: a method to establish benchmark structural variant calls Hemang M. Parikh, Marghoob Mohiyuddin, Hugo Y. K. Lam et al. · BMC Genomics Open access 15 Jan 2016 149
20 Phased Whole-Genome Genetic Risk in a Family Quartet Using a Major Allele Reference Sequence Frederick E. Dewey et al. · PLoS Genetics Open access 15 Sep 2011 149
21 Real-time dialogue between experimenters and dreamers during REM sleep Karen R. Konkoly, Kristoffer Appel, Emma Chabani et al. · Current Biology Open access 19 Feb 2021 132
22 Ultrasensitive ctDNA detection for preoperative disease stratification in early-stage lung adenocarcinoma James R. Black et al. · Nature Medicine Open access280 authors 2025 105
23 Are minor alleles more likely to be risk alleles? Takashi Kido, Weronika Sikora-Wohlfeld, Minae Kawashima et al. · BMC Medical Genomics Open access 19 Jan 2018 93
24 Stress, Anxiety, and Weight Gain among University and College Students: A Systematic Review Suzan A. Haidar, Nanné K. de Vries, Mirey Karavetian et al. · Journal of the Academy of Nutrition and Dietetics Review 30 Jan 2018 91
25 TIME TO ABANDON INTERNET ADDICTION? PREDICTING PROBLEMATIC INTERNET, GAME, AND SOCIAL MEDIA USE FROM PSYCHOSOCIAL WELL-BEING AND APPLICATION USE Antonius J. van Rooij, Christopher John Ferguson, Dike van de Mheen et al. · Research portal (Tilburg University) Open access 2017 91
26 A survey of current practices for genomic sequencing test interpretation and reporting processes in US laboratories Julianne M. O’Daniel et al. · Genetics in Medicine Open access 3 Nov 2016 89
27 High prevalence of focal and multi-focal somatic genetic variants in the human brain Michael John Keogh, Wei Wei, Juvid Aryaman et al. · Nature Communications Open access 9 Oct 2018 79
28 A variant by any name: quantifying annotation discordance across tools and clinical databases Jennifer L. Yen, Sarah Garcia, Aldrin Montana et al. · Genome Medicine Open access 24 Jan 2017 78
29 TPMT, COMT and ACYP2 genetic variants in paediatric cancer patients with cisplatin-induced ototoxicity Signe Thiesen, Peng Yin, Andrea Jorgensen et al. · Pharmacogenetics and Genomics Open access 25 Apr 2017 78
30 Transforming literature screening: The emerging role of large language models in systematic reviews Fernando M. Delgado-Chaves, Matthew James Jennings, António Atalaia et al. · Proceedings of the National Academy of Sciences ReviewOpen access 6 Jan 2025 76
31 Lymphocytic response to tumour and deficient DNA mismatch repair identify subtypes of stage II/III colorectal cancer associated with patient outcomes David S. Williams, Dmitri Mouradov, Robert N. Jorissen et al. · Gut 30 Jan 2018 76
32 The European Cancer Patient’s Bill of Rights, update and implementation 2016 Mark Lawler et al. · ESMO Open Open access 2016 74
33 Physical Activity and Sedentary Time: Association with Metabolic Health and Liver Fat Kelly A. Bowden Davies, Victoria S. Sprung, Juliette A. Norman et al. · Medicine & Science in Sports & Exercise Open access 29 Jan 2019 70
34 Exome sequencing in 32 patients with anophthalmia/microphthalmia and developmental eye defects Anne Michele Slavotinek et al. · Clinical Genetics Open access 2 Dec 2014 70
35 Effectiveness of a Web-Based Computer-Tailored Multiple-Lifestyle Intervention for People Interested in Reducing their Cardiovascular Risk: A Randomized Controlled Trial Vera Storm, Julia Dörenkämper, Dominique Alexandra Reinwand et al. · Journal of Medical Internet Research Open access 11 Apr 2016 67
36 Enabling miniaturised personalised diagnostics: from lab-on-a-chip to lab-in-a-drop Kevin M. Koo, Eugene J. H. Wee, Yuling Wang et al. · Lab on a Chip 2017 66
37 Prediction of Immunotherapy Response in Melanoma through Combined Modeling of Neoantigen Burden and Immune-Related Resistance Mechanisms Charles W. Abbott, Sean M. Boyle, Rachel Marty Pyke et al. · Clinical Cancer Research Open access Aug 2021 60
38 GPCR heteromers: An overview of their classification, function and physiological relevance Natasha C. Dale, Elizabeth K. M. Johnstone, Kevin D. G. Pfleger · Frontiers in Endocrinology Open access 30 Aug 2022 58
39 Achieving high-sensitivity for clinical applications using augmented exome sequencing Anil Jayant Patwardhan et al. · Genome Medicine Open access 15 Jul 2015 58
40 Disease Risk Factors Identified Through Shared Genetic Architecture and Electronic Medical Records Li Li, David Ruau, Chirag J. Patel et al. · Science Translational Medicine Open access 30 Apr 2014 57
41 Whole genome sequencing-powered ctDNA sequencing for breast cancer detection Isaac García-Murillas, Charles W. Abbott, Rosalind J. Cutts et al. · Annals of Oncology Open access 4 Feb 2025 56
42 Disease Variant Landscape of a Large Multiethnic Population of Moyamoya Patients by Exome Sequencing Lorelei D. Shoemaker, Michael James Clark, Anil Jayant Patwardhan et al. · G3 Genes Genomes Genetics Open access 10 Nov 2015 53
43 Early somatic mosaicism is a rare cause of long-QT syndrome James Rush Priest et al. · Proceedings of the National Academy of Sciences Open access 28 Sep 2016 51
44 Role of CD14+ monocyte-derived oxidised mitochondrial DNA in the inflammatory interferon type 1 signature in juvenile dermatomyositis Meredyth Wilkinson, DALE A. MOULDING, Thomas McDonnell et al. · Annals of the Rheumatic Diseases Open access 23 Dec 2022 49
45 Fluoropyrimidine chemotherapy: recommendations for DPYD genotyping and therapeutic drug monitoring of the Swiss Group of Pharmacogenomics and Personalised Therapy Seid Hamzic, Stefan Paul Aebi, Markus Joerger et al. · Swiss Medical Weekly Open access 24 Nov 2020 49
46 De Novo Occurrence of a Variant in ARL3 and Apparent Autosomal Dominant Transmission of Retinitis Pigmentosa Samuel P. Strom, Michael James Clark, Ariadna Martinez et al. · PLoS ONE Open access 10 Mar 2016 48
47 Epigenetic inactivation of the candidate tumor suppressorUSP44is a frequent and early event in colorectal neoplasia Mathew A. Sloane, Jason W.H. Wong, D. S. Perera et al. · Epigenetics Open access 16 May 2014 48
48 Ipilimumab alone or in combination with nivolumab in patients with advanced melanoma who have progressed or relapsed on PD-1 blockade: clinical outcomes and translational biomarker analyses Claire Frances Friedman, Christine N. Spencer, Christopher R. Cabanski et al. · Journal for ImmunoTherapy of Cancer Open access 2022 45
49 DNA methylation profiling distinguishes histological subtypes of renal cell carcinoma A Slater, Majed Saleh Alokail, Dean Gentle et al. · Epigenetics Open access 21 Feb 2013 44
50 Orexin Signaling: A Complex, Multifaceted Process Natasha C. Dale, Daniël Hoyer, Laura H. Jacobson et al. · Frontiers in Cellular Neuroscience Open access 13 Apr 2022 43

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.