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Institution · Pfizer (United States)

Most cited papers from Pfizer (United States)

What are the most cited papers from Pfizer (United States)?

The most cited paper from Pfizer (United States) is "Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings 1PII of original article: S0169-409X(96)00423-1. The article was originally published in Advanced Drug Delivery Reviews 23 (1997) 3–25. 1" (Christopher A. Lipinski, Franco Lombardo, Beryl W. Dominy et al., 2001), with 18,154 citations. Next come "An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest" (14,405) and "Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings" (11,492).

Showing 50 of 59 papers. Every paper with more than 2,275 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings 1PII of original article: S0169-409X(96)00423-1. The article was originally published in Advanced Drug Delivery Reviews 23 (1997) 3–25. 1 Christopher A. Lipinski, Franco Lombardo, Beryl W. Dominy et al. · Advanced Drug Delivery Reviews Review Mar 2001 18,154
2 An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest Rahul S. Desikan, Florent Ségonne, Bruce R. Fischl et al. · NeuroImage 14 Mar 2006 14,405
3 Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings Christopher A. Lipinski, Franco Lombardo, Beryl W. Dominy et al. · Advanced Drug Delivery Reviews Review 1997 11,492
4 2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative Daniel Aletaha et al. · Arthritis & Rheumatism Open access 10 Aug 2010 9,731
5 Biological insights from 108 schizophrenia-associated genetic loci Stephan Ripke et al. · Nature Open access297 authors Jul 2014 8,181
6 Lead- and drug-like compounds: the rule-of-five revolution Christopher A. Lipinski · Drug Discovery Today Technologies Dec 2004 6,290
7 Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) Daniel J. Klionsky et al. · Autophagy Open access2,467 authors 2 Jan 2016 6,023
8 Cardiac-Resynchronization Therapy with or without an Implantable Defibrillator in Advanced Chronic Heart Failure Michael R. Bristow, Leslie Ann Saxon, JOHN P. BOEHMER et al. · New England Journal of Medicine 19 May 2004 5,848
9 Clinical importance of changes in chronic pain intensity measured on an 11-point numerical pain rating scale John T. Farrar, James P. Young, Linda LaMoreaux et al. · Pain Nov 2001 5,825
10 Sunitinib versus Interferon Alfa in Metastatic Renal-Cell Carcinoma Robert John Motzer, Thomas E. Hutson, Piotr Tomczak et al. · New England Journal of Medicine Open access 10 Jan 2007 5,801
11 Principles of Good Practice for the Translation and Cultural Adaptation Process for Patient-Reported Outcomes (PRO) Measures: Report of the ISPOR Task Force for Translation and Cultural Adaptation Diane J. Wild, Alyson Grove, Mona L. Martin et al. · Value in Health Open access Mar 2005 5,609
12 Proposed minimum reporting standards for chemical analysis Lloyd W. Sumner et al. · Metabolomics Open access 11 Sep 2007 5,359
13 The biology and management of non-small cell lung cancer Roy S. Herbst, Daniel Morgensztern, CHRIS H. BOSHOFF · Nature 2018 5,116
14 Genetic effects on gene expression across human tissues François Aguet et al. · Nature Open access250 authors 10 Oct 2017 4,762
15 Anaplastic Lymphoma Kinase Inhibition in Non–Small-Cell Lung Cancer Eunice Lee Kwak et al. · New England Journal of Medicine Open access 27 Oct 2010 4,517
16 MET Amplification Leads to Gefitinib Resistance in Lung Cancer by Activating ERBB3 Signaling Jeffrey A. Engelman, Kreshnik Zejnullahu, Tetsuya Mitsudomi et al. · Science 26 Apr 2007 4,504
17 FinnGen provides genetic insights from a well-phenotyped isolated population Mitja Kurki et al. · Nature Open access169 authors 18 Jan 2023 4,362
18 Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage Takeshi Nishikawa, Diane Edelstein, Xue Liang Du et al. · Nature Apr 2000 4,302
19 Core outcome measures for chronic pain clinical trials: IMMPACT recommendations Robert H. Dworkin et al. · Pain 6 Nov 2004 3,789
20 Macromodel—an integrated software system for modeling organic and bioorganic molecules using molecular mechanics Fariborz Mohamadi, Nigel G. J. Richards, Wayne C. Guida et al. · Journal of Computational Chemistry May 1990 3,774
21 Drug-like properties and the causes of poor solubility and poor permeability Christopher A. Lipinski · Journal of Pharmacological and Toxicological Methods Jul 2000 3,766
22 Genotypic and Histological Evolution of Lung Cancers Acquiring Resistance to EGFR Inhibitors Lecia Van Dam Sequist et al. · Science Translational Medicine Open access 23 Mar 2011 3,603
23 How many drug targets are there? John P. Overington, Bissan Al‐Lazikani, Andrew L. Hopkins · Nature Reviews Drug Discovery Review Dec 2006 3,554
24 Core outcome domains for chronic pain clinical trials: IMMPACT recommendations Dennis C. Turk et al. · Pain 22 Sep 2003 3,518
25 Intensive Lipid Lowering with Atorvastatin in Patients with Stable Coronary Disease John C. LaRosa, Scott M. Grundy, David D. Waters et al. · New England Journal of Medicine Open access 9 Mar 2005 3,517
26 Interpreting the Clinical Importance of Treatment Outcomes in Chronic Pain Clinical Trials: IMMPACT Recommendations Robert H. Dworkin et al. · Journal of Pain Open access 13 Dec 2007 3,496
27 Crizotinib versus Chemotherapy in Advanced ALK -Positive Lung Cancer Alice Tsang Shaw et al. · New England Journal of Medicine Open access Jun 2013 3,429
28 Membrane transporters in drug development Kathleen M. Giacomini et al. · Nature Reviews Drug Discovery ReviewOpen access Mar 2010 3,373
29 Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression eQTLGen et al. · Nature Genetics Open access218 authors 26 Apr 2018 3,347
30 The druggable genome Andrew L. Hopkins, Colin R. Groom · Nature Reviews Drug Discovery Sep 2002 3,335
31 Voriconazole versus Amphotericin B for Primary Therapy of Invasive Aspergillosis Raoul Herbrecht et al. · New England Journal of Medicine Open access 8 Aug 2002 3,326
32 Applications of machine learning in drug discovery and development Jessica J. Vamathevan, Dominic A. Clark, Paul Czodrowski et al. · Nature Reviews Drug Discovery ReviewOpen access 11 Apr 2019 3,274
33 A Novel Serum Protein Similar to C1q, Produced Exclusively in Adipocytes Philipp E. Scherer, Suzanne P. Williams, Michael Fogliano et al. · Journal of Biological Chemistry Open access Nov 1995 3,253
34 First-Line Crizotinib versus Chemotherapy in ALK -Positive Lung Cancer Benjamin J. Solomon, Tony S.K. Mok, Dong‐Wan Kim et al. · New England Journal of Medicine Open access 3 Dec 2014 3,251
35 Effects of Torcetrapib in Patients at High Risk for Coronary Events Philip J. Barter, Mark J. Caulfield, Mats A. L. Eriksson et al. · New England Journal of Medicine Open access 5 Nov 2007 3,168
36 Eplerenone in Patients with Systolic Heart Failure and Mild Symptoms Faiez M. Zannad, John J.V. McMurray, Henry Krum et al. · New England Journal of Medicine Open access 14 Nov 2010 3,112
37 Development and evaluation of an abridged, 5-item version of the International Index of Erectile Function (IIEF-5) as a diagnostic tool for erectile dysfunction RC Rosen, JC Cappelleri, MD Smith et al. · International Journal of Impotence Research Dec 1999 3,073
38 Palbociclib and Letrozole in Advanced Breast Cancer Richard S. Finn, Miguel Martín, Hope S. Rugo et al. · New England Journal of Medicine 16 Nov 2016 3,059
39 Mapping genomic loci implicates genes and synaptic biology in schizophrenia Vassily Vladimirovich Trubetskoy et al. · Nature Open access613 authors 8 Apr 2022 2,894
40 Tafamidis Treatment for Patients with Transthyretin Amyloid Cardiomyopathy Matthew J. Maurer et al. · New England Journal of Medicine Open access 27 Aug 2018 2,841
41 The PI3K Pathway in Human Disease David A. Fruman, Honyin Chiu, Benjamin David Hopkins et al. · Cell Open access Aug 2017 2,806
42 Comparison of pain syndromes associated with nervous or somatic lesions and development of a new neuropathic pain diagnostic questionnaire (DN4) Didier Bouhassira, Nadine Attal, H. Alchaar et al. · Pain 29 Jan 2005 2,755
43 Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1 Daniel J. Klionsky et al. · Autophagy Open access2,930 authors 2 Jan 2021 2,743
44 A synthetic inhibitor of the mitogen-activated protein kinase cascade. David T. Dudley, Long Pang, Stuart J. Decker et al. · Proceedings of the National Academy of Sciences Open access 15 Aug 1995 2,717
45 From Vulnerable Plaque to Vulnerable Patient Morteza Naghavi et al. · Circulation 13 Oct 2003 2,670
46 Population-Based Survey of Urinary Incontinence, Overactive Bladder, and Other Lower Urinary Tract Symptoms in Five Countries: Results of the EPIC Study Debra E. Irwin, Ian Milsom, Steinar Hunskaar et al. · European Urology 3 Oct 2006 2,647
47 Atorvastatin in Patients with Type 2 Diabetes Mellitus Undergoing Hemodialysis Christoph Wanner, Vera Krane, Winfried März et al. · New England Journal of Medicine Open access 20 Jul 2005 2,634
48 AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC Veit Hornung, Andrea Ablasser, Marie Charrel-Dennis et al. · Nature Open access 21 Jan 2009 2,632
49 Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial George D. Demetri, Allan T. van Oosterom, Christopher R. Garrett et al. · The Lancet Oct 2006 2,626
50 New insights into the genetic etiology of Alzheimer’s disease and related dementias Céline Bellenguez et al. · Nature Genetics Open access1,266 authors Apr 2022 2,608

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.