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Most cited papers from PharmacoGenetics (China)

What are the most cited papers from PharmacoGenetics (China)?

The most cited paper from PharmacoGenetics (China) is "Global colorectal cancer burden in 2020 and projections to 2040" (Yue Xi, Pengfei Xu, 2021), with 2,543 citations. Next come "Serum amyloid A, the major vertebrate acute‐phase reactant" (1,124) and "An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans" (830).

Showing 50 of 60 papers. Every paper with more than 200 citations is listed.

Most cited papers, sortable by citations and release date
#Paper
1 Global colorectal cancer burden in 2020 and projections to 2040 Yue Xi, Pengfei Xu · Translational Oncology Open access 6 Jul 2021 2,543
2 Serum amyloid A, the major vertebrate acute‐phase reactant Clarissa Uhlar, Alexander Steven Whitehead · European Journal of Biochemistry Open access Oct 1999 1,124
3 An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans Robert A. Scott et al. · Diabetes Open access175 authors 31 May 2017 830
4 Rare and low-frequency coding variants alter human adult height Eirini Marouli et al. · Nature Open access373 authors 31 Jan 2017 665
5 Gene-Expression Patterns in Drug-Resistant Acute Lymphoblastic Leukemia Cells and Response to Treatment Amy de Haar-Holleman, Meyling Hua-Chen Cheok, Monique L. den Boer et al. · New England Journal of Medicine Open access 4 Aug 2004 646
6 A SNAIL1–SMAD3/4 transcriptional repressor complex promotes TGF-β mediated epithelial–mesenchymal transition C. Theresa Vincent, Etienne P.A. Neve, Jill R. Johnson et al. · Nature Cell Biology Open access 13 Jul 2009 646
7 Nonviral gene therapy: promises and challenges S Li, Leaf Huang · Gene Therapy 2000 615
8 Cutting Edge: TIGIT Has T Cell-Intrinsic Inhibitory Functions Nicole Joller, Jason P. Hafler, Boel Brynedal et al. · The Journal of Immunology Open access 3 Jan 2011 581
9 Nonviral Vectors in the New Millennium: Delivery Barriers in Gene Transfer Makiya Nishikawa, Leaf Huang · Human Gene Therapy 20 May 2001 576
10 Enhanced Gαq signaling: A common pathway mediates cardiac hypertrophy and apoptotic heart failure John W. Adams, Yoshihito Sakata, Michael G. Davis et al. · Proceedings of the National Academy of Sciences Open access 18 Aug 1998 535
11 Trans-ethnic association study of blood pressure determinants in over 750,000 individuals Understanding Society Scientific Group et al. · Nature Genetics Open access100 authors 19 Dec 2018 512
12 ABT-378, a Highly Potent Inhibitor of the Human Immunodeficiency Virus Protease Hing Leung Sham et al. · Antimicrobial Agents and Chemotherapy Open access Dec 1998 473
13 PI3K/Akt/mTOR pathway as a target for cancer therapy Daniel Morgensztern, Howard L. McLeod · Anti-Cancer Drugs 11 Aug 2005 472
14 Characterization of Foxp3+CD4+CD25+ and IL-10-Secreting CD4+CD25+ T Cells during Cure of Colitis Holm H. Uhlig, Janine L. Coombes, Christian Mottet et al. · The Journal of Immunology Open access Nov 2006 454
15 The Pharmacogene Variation (PharmVar) Consortium: Incorporation of the Human Cytochrome P450 ( CYP ) Allele Nomenclature Database Andrea Gaedigk, Magnus Ingelman‐Sundberg, Neil Miller et al. · Clinical Pharmacology & Therapeutics Open access 14 Nov 2017 436
16 Favipiravir: Pharmacokinetics and Concerns About Clinical Trials for 2019‐nCoV Infection Yin‐Xiao Du, Xiaoping Chen · Clinical Pharmacology & Therapeutics 4 Apr 2020 429
17 Finerenone, a Novel Selective Nonsteroidal Mineralocorticoid Receptor Antagonist Protects From Rat Cardiorenal Injury Peter Kolkhof, Martina Delbeck, Axel Kretschmer et al. · Journal of Cardiovascular Pharmacology 11 Mar 2014 427
18 An Important Role for Type III Interferon (IFN-λ/IL-28) in TLR-Induced Antiviral Activity Nina Ank, Marie Beck Iversen, Christina Bartholdy et al. · The Journal of Immunology Feb 2008 427
19 Expression cloning and signaling properties of the rat glucagon receptor L. Jelinek, Si Lok, Gilad Rosenberg et al. · Science 12 Mar 1993 401
20 Nomenclature for human CYP2D6 alleles Ann K. Daly, Jürgen Brockmöller, Franck Broly et al. · Pharmacogenetics Jun 1996 400
21 Large-scale structure of genomic methylation patterns Robert A. Rollins, Fatemeh G. Haghighi, John R. Edwards et al. · Genome Research Open access 19 Dec 2005 384
22 Epidemiology of esophageal cancer in 2020 and projections to 2030 and 2040 Chunquan Liu, Yun‐Lei Ma, Qi Qin et al. · Thoracic Cancer Open access 8 Dec 2022 370
23 Polymeric Micelles: Nanocarriers for Cancer-Targeted Drug Delivery Yifei Zhang, Yixian Huang, Song Li · AAPS PharmSciTech Open access 3 Apr 2014 367
24 Comprehensive elaboration of the cGAS-STING signaling axis in cancer development and immunotherapy Juyan Zheng, Junluan Mo, Tao Zhu et al. · Molecular Cancer Open access 27 Aug 2020 347
25 JAK/STAT pathway: Extracellular signals, diseases, immunity, and therapeutic regimens Qian Hu, Qihui Bian, Ding‐Chao Rong et al. · Frontiers in Bioengineering and Biotechnology Open access 23 Feb 2023 339
26 Nintedanib: From Discovery to the Clinic Gerald J. Roth, Rudolf F. Binder, Florian Colbatzky et al. · Journal of Medicinal Chemistry Open access 4 Dec 2014 338
27 Cutting Edge: IL-21 Is a Switch Factor for the Production of IgG1 and IgG3 by Human B Cells Jérôme Pène, Jean‐François Gauchat, Sandrine Lécart et al. · The Journal of Immunology May 2004 317
28 The Vanilloid Receptor TRPV1 Is Tonically Activated In Vivo and Involved in Body Temperature Regulation Narender R. Gavva, Anthony W. Bannon, Sekhar Surapaneni et al. · Journal of Neuroscience Open access 28 Mar 2007 314
29 Implementing Pharmacogenomics in Europe: Design and Implementation Strategy of the Ubiquitous Pharmacogenomics Consortium Cathelijne H. van der Wouden et al. · Clinical Pharmacology & Therapeutics Open access 27 Dec 2016 308
30 Immunoglobulin deposition on biomolecule corona determines complement opsonization efficiency of preclinical and clinical nanoparticles Vivian Pham Vu, Geoffrey B. Gifford, Fangfang Chen et al. · Nature Nanotechnology Open access 30 Dec 2018 307
31 A Novel Role for the Dioxin Receptor in Fatty Acid Metabolism and Hepatic Steatosis Jung Hoon Lee, Taira Wada, Maria Febbraio et al. · Gastroenterology Open access 18 Mar 2010 282
32 Genetic polymorphism of CYP2C9 and its effect on warfarin maintenance dose requirement in patients undergoing anticoagulation therapy Hirokazu Furuya, Pedro M. Fernández‐Salguero, W. Larry Gregory et al. · Pharmacogenetics Dec 1995 280
33 MALAT1: a potential biomarker in cancer Zhixing Li, Qiong-Ni Zhu, Haibo Zhang et al. · Cancer Management and Research Open access Dec 2018 275
34 Evaluation of dosing strategy for pembrolizumab for oncology indications Tomoko Freshwater, Anna Georgieva Kondic, Malidi Ahamadi et al. · Journal for ImmunoTherapy of Cancer Open access 9 May 2017 268
35 IL-21 Enhances and Sustains CD8+ T Cell Responses to Achieve Durable Tumor Immunity: Comparative Evaluation of IL-2, IL-15, and IL-21 A. P. Moroz, Cheryl Eppolito, Qingsheng Li et al. · The Journal of Immunology Jul 2004 267
36 Mode of action and human relevance analysis for nuclear receptor-mediated liver toxicity: A case study with phenobarbital as a model constitutive androstane receptor (CAR) activator Clifford R. Elcombe, Richard C. Peffer, Douglas C. Wolf et al. · Critical Reviews in Toxicology Open access 4 Nov 2013 266
37 Role of BCRP 421C>A polymorphism on rosuvastatin pharmacokinetics in healthy Chinese males Wei Zhang, Bangning Yu, Yijing He et al. · Clinica Chimica Acta 14 May 2006 265
38 Glycemic variability: adverse clinical outcomes and how to improve it? Zheng Gang Zhou, Bao Sun, Shiqiong Huang et al. · Cardiovascular Diabetology Open access 4 Jul 2020 264
39 PARP1 promotes nucleotide excision repair through DDB2 stabilization and recruitment of ALC1 Alex Pines, Mischa G. Vrouwe, Jurgen A. F. Marteijn et al. · The Journal of Cell Biology Open access 8 Oct 2012 260
40 The NuRD chromatin–remodeling complex regulates signaling and repair of DNA damage Godelieve Smeenk, Wouter W. Wiegant, Hans C. J. Vrolijk et al. · The Journal of Cell Biology Open access 30 Aug 2010 248
41 A Novel Constitutive Androstane Receptor-Mediated and CYP3A-Independent Pathway of Bile Acid Detoxification Simrat P. S. Saini, Junichiro Sonoda, Li Xu et al. · Molecular Pharmacology 23 Jan 2004 248
42 Roles of circular RNAs in immune regulation and autoimmune diseases Zheng Gang Zhou, Bao Sun, Shiqiong Huang et al. · Cell Death and Disease Open access 26 Jun 2019 244
43 Pharmacogenomics of drug-metabolizing enzymes: a recent update on clinical implications and endogenous effects Sarah C. Sim, Marina Kacevska, Magnus Ingelman‐Sundberg · The Pharmacogenomics Journal 23 Oct 2012 244
44 In Vivo Knockdown of Pathogenic Proteins via Specific and Nongenetic Inhibitor of Apoptosis Protein (IAP)-dependent Protein Erasers (SNIPERs) Nobumichi Ohoka, Keiichiro Okuhira, Masahiro Ito et al. · Journal of Biological Chemistry Open access 3 Feb 2017 241
45 MicroRNA-30c inhibits human breast tumour chemotherapy resistance by regulating TWF1 and IL-11 Jessica Bockhorn, Rachel Dalton, Chika Nwachukwu et al. · Nature Communications Open access 22 Jan 2013 239
46 The Constitutive Androstane Receptor Is an Anti-obesity Nuclear Receptor That Improves Insulin Sensitivity Jie Gao, Jinhan He, Yonggong Zhai et al. · Journal of Biological Chemistry Open access 18 Jul 2009 237
47 Low- and high-level transgenic expression of β 2 -adrenergic receptors differentially affect cardiac hypertrophy and function in Gαq-overexpressing mice Gerald W. Dorn, Nicole M. Tepe, John N. Lorenz et al. · Proceedings of the National Academy of Sciences Open access 25 May 1999 231
48 The N-end rule pathway: emerging functions and molecular principles of substrate recognition Shashikanth M. Sriram, Bo Yeon Kim, Yong Tae Kwon · Nature Reviews Molecular Cell Biology Review 21 Oct 2011 229
49 THE MAIN ROLE OF UGT1A9 IN THE HEPATIC METABOLISM OF MYCOPHENOLIC ACID AND THE EFFECTS OF NATURALLY OCCURRING VARIANTS Olivier Bernard, Chantal Guillemette · Drug Metabolism and Disposition 21 Jul 2004 228
50 Constitutive activities of estrogen-related receptors: Transcriptional regulation of metabolism by the ERR pathways in health and disease Janice M. Huss, Wojciech G. Garbacz, Wen Li Xie · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease Open access 24 Jun 2015 226

Citations are OpenAlex's own counts, from its 2026-09-23 snapshot, so the ranking can differ from Google Scholar or Web of Science. A paper is listed for an institution when any of its authors gave it as an affiliation; retracted papers and papers whose citation count cannot be traced to citing works are left out, and a preprint and the article it became are shown once. Release dates are OpenAlex's: where a source gave only a month or a year, that is what is shown. How the lists are chosen.